Berger N, van der Wel T, Hirschmugl B, Baernthaler T, Gindlhuber J, Fawzy N, Eichmann T, Birner-Gruenberger R, Zimmermann R, van der Stelt M, Wadsack C (2023)
Inhibition of diacylglycerol lipase beta modulates lipid and endocannabinoid levels in the ex vivo human placenta
Front Endocrinol (Lausanne) 14: 1092024
Bradic I, Kuentzel KB, Honeder S, Grabner GF, Vujic N, Zimmermann R, Birner-Gruenberger R, Kratky D (2022)
Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases
Mol Metab
Eisner H, Riegler-Berket L, Gamez CFR, Sagmeister T, Chalhoub G, Darnhofer B, Jazleena PJ, Birner-Gruenberger R, Pavkov-Keller T, Haemmerle G, Schoiswohl G, Oberer M (2022)
The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1
Int J Mol Sci 23:
Schittmayer M, Vujic N, Darnhofer B, Korbelius M, Honeder S, Kratky D, Birner-Gruenberger R (2020)
Spatially resolved activity-based proteomic profiles of the murine small intestinal lipases
Mol Cell Proteomics 19: 2104
Wallace PW, Haernvall K, Ribitsch D, Zitzenbacher S, Schittmayer M, Steinkellner G, Gruber K, Guebitz GM, Birner-Gruenberger R (2017)
PpEst is a novel PBAT degrading polyesterase identified by proteomic screening of Pseudomonas pseudoalcaligenes
Applied Microbiology & Biotechnology 101: 2291
Aschauer P, Rengachari S, Lichtenegger J, Schittmayer M, Das KM, Mayer N, Breinbauer R, Birner-Gruenberger R, Gruber CC, Zimmermann R, Gruber K, Oberer M (2016)
Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p
Biochimica & Biophysica Acta 1861: 462
Radovic B, Vujic N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D (2016)
Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice
Diabetologia 59: 1743
Trieb M, Horvath A, Birner-Gruenberger R, Spindelboeck W, Stadlbauer V, Taschler U, Curcic S, Stauber RE, Holzer M, Pasterk L, Heinemann A, Marsche G (2016)
Liver disease alters high-density lipoprotein composition, metabolism and function
Biochimica & Biophysica Acta 1861: 630
Birner-Gruenberger R, Breinbauer R (2015)
Weighing the proteasome for covalent modifications
Chemical Biology 22: 315
Leypold M, Wallace PW, Kljajic M, Schittmayer M, Pletz J, Illaszewicz-Trattner C, Guebitz GM, Birner-Gruenberger R, Breinbauer R (2015)
A robust and simple protocol for the synthesis of arylfluorophosphonates
Tetrahedron Letters 56: 5619
Sahu-Osen A, Montero-Moran G, Schittmayer M, Fritz K, Dinh A, Chang YF, McMahon D, Boeszoermenyi A, Cornaciu I, Russell D, Oberer M, Carman GM, Birner-Gruenberger R, Brasaemle DL (2015)
CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization
J Lipid Res 56: 109
Rengachari S, Aschauer P, Schittmayer M, Mayer N, Gruber K, Breinbauer R, Birner-Gruenberger R, Dreveny I, Oberer M (2013)
Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase
Journal of Biological Chemistry 288: 31093
Sreckovic I, Birner-Gruenberger R, Obrist B, Stojakovic T, Scharnagl H, Holzer M, Scholler M, Philipose S, Marsche G, Lang U, Desoye G, Wadsack C (2013)
Distinct composition of human fetal HDL attenuates its anti-oxidative capacity
Biochimica & Biophysica Acta 1831: 737
Birner-Gruenberger R, Bickmeyer I, Lange J, Hehlert P, Hermetter A, Kollroser M, Rechberger GN, Kuhnlein RP (2012)
Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster a-Esterase-7
Insect Biochemistry & Molecular Biology 42: 220
Birner-Gruenberger R, Darnhofer B, Chen WQ, Monje FJ, Lubec G (2012)
Proteomic characterization of the abdominal ganglion of Aplysia californica-a protein resource for neuroscience
Proteomics 12: 2482
Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R (2012)
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase
Cell Metab 15: 691
Ribitsch D, Heumann S, Karl W, Gerlach J, Leber R, Birner-Gruenberger R, Gruber K, Eiteljoerg I, Remler P, Siegert P, Lange J, Maurer KH, Berg G, Guebitz GM, Schwab H (2012)
Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli
J Biotechnol 157: 140
Schittmayer M, Birner-Gruenberger R (2012)
Lipolytic proteomics
Mass Spectrom Rev 31: 570
Viertler M, Schittmayer M, Birner-Gruenberger R (2012)
Activity based subcellular resolution imaging of lipases
Bioorganic & Medicinal Chemistry 20: 628
Ribitsch D, Heumann S, Trotscha E, Herrero Acero E, Greimel K, Leber R, Birner-Gruenberger R, Deller S, Eiteljoerg I, Remler P, Weber T, Siegert P, Maurer KH, Donelli I, Freddi G, Schwab H, Guebitz GM (2011)
Hydrolysis of polyethyleneterephthalate by p-nitrobenzylesterase from Bacillus subtilis
Biotechnol Prog 27: 951
Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Frohlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D (2010)
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363
J Lipid Res 51: 2896
Schicher M, Morak M, Birner-Gruenberger R, Kayer H, Stojcic B, Rechberger G, Kollroser M, Hermetter A (2010)
Functional proteomic analysis of lipases and esterases in cultured human adipocytes
J Proteome Res 9: 6334
Morak M, Schmidinger H, Krempl P, Rechberger G, Kollroser M, Birner-Gruenberger R, Hermetter A (2009)
Differential activity-based gel electrophoresis for comparative analysis of lipolytic and esterolytic activities
J Lipid Res 50: 1281
Schicher M, Jesse I, Birner-Gruenberger R (2009)
Activity-based profiling of lipases in living cells
Methods Mol Biol 580: 251
Schittmayer M, Birner-Gruenberger R (2009)
Functional proteomics in lipid research: lipases, lipid droplets and lipoproteins
J Proteomics 72: 1006
Birner-Gruenberger R, Susani-Etzerodt H, Kollroser M, Rechberger GN, Hermetter A (2008)
Lipolytic and esterolytic activity-based profiling of murine liver
Proteomics 8: 3645
Hermann M, Kietzmann MU, Ivancic M, Zenzmaier C, Luiten RG, Skranc W, Wubbolts M, Winkler M, Birner-Gruenberger R, Pichler H, Schwab H (2008)
Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst
J Biotechnol 133: 301
Birner-Gruenberger R, Hermetter A (2007)
Activity-based proteomics of lipolytic enzymes
Curr Drug Discov Technol 4: 1
Schmidinger H, Hermetter A, Birner-Gruenberger R (2006)
Activity-based proteomics: enzymatic activity profiling in complex proteomes
Amino Acids 30: 333
Schmidinger H, Susani-Etzerodt H, Birner-Gruenberger R, Hermetter A (2006)
Inhibitor and protein microarrays for activity-based recognition of lipolytic enzymes
Chembiochem 7: 527
Susani-Etzerodt H, Schmidinger H, Riesenhuber G, Birner-Gruenberger R, Hermetter A (2006)
A versatile library of activity-based probes for fluorescence detection and/or affinity isolation of lipolytic enzymes
Chemistry & Physic of Lipids 144: 60
Birner-Gruenberger R, Susani-Etzerodt H, Waldhuber M, Riesenhuber G, Schmidinger H, Rechberger G, Kollroser M, Strauss JG, Lass A, Zimmermann R, Haemmerle G, Zechner R, Hermetter A (2005)
The lipolytic proteome of mouse adipose tissue
Mol Cell Proteomics 4: 1710
Schmidinger H, Birner-Gruenberger R, Riesenhuber G, Saf R, Susani-Etzerodt H, Hermetter A (2005)
Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases
Chembiochem 6: 1776