Elfsmark L, gren L, Akfur C, Jonasson S (2022) <br />Ammonia exposure by intratracheal instillation causes severe and deteriorating lung injury and vascular effects in mice<br /><i>Inhal Toxicol</i> <b>34</b>: 145<br /><br />Lindgren C, Forsgren N, Hoster N, Akfur C, Artursson E, Edvinsson L, Svensson R, Worek F, Ekstrom, Linusson A (2022) <br />Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase<br /><i>Chemistry</i> <br /><br />Allgardsson A, David Andersson C, Akfur C, Worek F, Linusson A, Ekstrom F (2017) <br />An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet<br /><i>Molecules</i> <b>22</b>: <br /><br />Allgardsson A, Berg L, Akfur C, Hornberg A, Worek F, Linusson A, Ekstrom F (2016) <br />Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6<br /><i>Proc Natl Acad Sci U S A</i> <b>113</b>: 5514<br /><br />Andersson CD, Hillgren JM, Lindgren C, Qian W, Akfur C, Berg L, Ekstrom F, Linusson A (2015) <br />Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase<br /><i>J Comput Aided Mol Des</i> <b>29</b>: 199<br /><br />Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian W, Ekstrom F, Linusson A (2013) <br />Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors<br /><i>Journal of Medicinal Chemistry</i> <b>56</b>: 7615<br /><br />Artursson E, Andersson PO, Akfur C, Linusson A, Borjegren S, Ekstrom F (2013) <br />Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: possible implications for the HI-6 antidote substrate specificity<br /><i>Biochemical Pharmacology</i> <b>85</b>: 1389<br /><br />Artursson E, Akfur C, Hornberg A, Worek F, Ekstrom F (2009) <br />Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis<br /><i>Toxicology</i> <b>265</b>: 108<br /><br />Ekstrom F, Akfur C, Tunemalm AK, Lundberg S (2006) <br />Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase<br /><i>Biochemistry</i> <b>45</b>: 74<br /><br />Ekstrom F, Pang YP, Boman M, Artursson E, Akfur C, Borjegren S (2006) <br />Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates<br /><i>Biochemical Pharmacology</i> <b>72</b>: 597<br /><br />