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Paper(s) concerning Tacrine

68 reference(s) found.
Listing paper details in reverse chronological order.
We are grateful to Keith Bradnam for improvment of this script

    Title: Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery
    Dileep KV, Ihara K, Mishima-Tsumagari C, Kukimoto-Niino M, Yonemochi M, Hanada K, Shirouzu M, Zhang KYJ
    Ref: Int J Biol Macromol, 210:172, 2022 : PubMed


    Title: Kinetic analysis of the toxicological effect of tacrine (Cognex) on human retinal acetylcholinesterase activity
    Alhomida AS, Al-Rajhi AA, Kamal MA, Al-Jafari AA
    Ref: Toxicology, 147:33, 2000 : PubMed


    Title: Huprine X is a Novel High-Affinity Inhibitor of Acetylcholinesterase That Is of Interest for Treatment of Alzheimer's Disease
    Camps P, Cusack B, Mallender WD, Achab RE, Morral J, Munoz-Torrero D, Rosenberry TL
    Ref: Molecular Pharmacology, 57:409, 2000 : PubMed


    Title: Mass psychogenic illness attributed to toxic exposure at a high school
    Heuser G
    Ref: N Engl J Med, 342:1674; author reply 1675, 2000 : PubMed


    Title: Combining tacrine with milameline reverses a scopolamine-induced impairment of continuous performance in rhesus monkeys
    Callahan MJ
    Ref: Psychopharmacology (Berl), 144:234, 1999 : PubMed


    Title: In vivo PET study of cerebral [11C] methyl- tetrahydroaminoacridine distribution and kinetics in healthy human subjects
    Traykov L, Tavitian B, Jobert A, Boller F, Forette F, Crouzel C, Di Giamberardino L, Pappata S
    Ref: Eur Journal of Neurology, 6:273, 1999 : PubMed


    Title: Syntheses of benzoquinolizidine and benzoindolizidine derivatives as anti-amnesic agents
    Zhao S, Totleben MJ, Freeman JP, Bacon CL, Fox GB, O'Driscoll E, Foley AG, Kelly J, Farrell U and Szmuszkovicz J <2 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 7:1637, 1999 : PubMed


    Title: Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release
    Allal C, Lazartigues E, Tran MA, Brefel-Courbon C, Gharib C, Montastruc JL, Rascol O
    Ref: European Journal of Pharmacology, 348:191, 1998 : PubMed


    Title: Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease
    Badia A, Banos JE, Camps P, Contreras J, Gorbig DM, Munoz-Torrero D, Simon M, Vivas NM
    Ref: Bioorganic & Medicinal Chemistry, 6:427, 1998 : PubMed


    Title: Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities
    Cheng DH, Tang XC
    Ref: Pharmacol Biochem Behav, 60:377, 1998 : PubMed


    Title: Inhibition of cholinesterase-associated aryl acylamidase activity by anticholinesterase agents: focus on drugs potentially effective in Alzheimer's disease
    Costagli C, Galli A
    Ref: Biochemical Pharmacology, 55:1733, 1998 : PubMed


    Title: Responses induced by tacrine in neuronal and non-neuronal cell lines
    De Ferrari GV, Von Bernhardi R, Calderon FH, Luza SC, Inestrosa NC
    Ref: Journal of Neuroscience Research, 52:435, 1998 : PubMed


    Title: Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: from tacrine to future applications
    Giacobini E
    Ref: Neurochem Int, 32:413, 1998 : PubMed


    Title: Effect of subchronic treatment with metrifonate and tacrine on brain cholinergic function in aged F344 rats
    Giovannini MG, Scali C, Bartolini L, Schmidt B, Pepeu G
    Ref: European Journal of Pharmacology, 354:17, 1998 : PubMed


    Title: Safety of tacrine: clinical trials, treatment IND, and postmarketing experience
    Gracon SI, Knapp MJ, Berghoff WG, Pierce M, DeJong R, Lobbestael SJ, Symons J, Dombey SL, Luscombe FA, Kraemer D
    Ref: Alzheimer Disease & Associated Disorders, 12:93, 1998 : PubMed


    Title: Penetration of tacrine into cerebrospinal fluid in patients with Alzheimer's disease
    Grothe DR, Piscitelli SC, Dukoff R, Fullerton T, Sunderland T, Molchan SE
    Ref: J Clin Psychopharmacol, 18:78, 1998 : PubMed


    Title: Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats
    Meyer EM, King MA, Meyers C
    Ref: Brain Research, 786:252, 1998 : PubMed


    Title: Functional and subcellular organelle changes in isolated rat and human hepatocytes induced by tetrahydroaminoacridine
    Monteith DK, Theiss JC, Haskins JR, de la Iglesia FA
    Ref: Archives of Toxicology, 72:147, 1998 : PubMed


    Title: Effects of AF102B and tacrine on delayed match-to-sample in monkeys
    O'Neill J, Fitten LJ, Siembieda D, Halgren E, Kim E, Fisher A, Perryman K
    Ref: Prog Neuropsychopharmacol Biological Psychiatry, 22:665, 1998 : PubMed


    Title: Shuttle-box avoidance learning in mice: improvement by combined glucose and tacrine
    Pavone F, Capone F, Battaglia M, Sansone M
    Ref: Neurobiol Learn Mem, 69:204, 1998 : PubMed


    Title: Tetrahydroaminoacridine improves the recency effect in Alzheimer's disease
    Riekkinen M, Soininen H, Riekkinen P, Sr., Kuikka J, Laakso M, Helkala EL, Partanen J, Riekkinen P, Jr.
    Ref: Neuroscience, 83:471, 1998 : PubMed


    Title: Tetrahydroaminoacridine, a cholinesterase inhibitor, and D-cycloserine, a partial NMDA receptor-associated glycine site agonist, enhances acquisition of spatial navigation
    Riekkinen P, Jr., Ikonen S, Riekkinen M
    Ref: Neuroreport, 9:1633, 1998 : PubMed


    Title: Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells
    Svensson AL, Nordberg A
    Ref: Neuroreport, 9:1519, 1998 : PubMed


    Title: Capillary zone electrophoretic determination of some drugs against Alzheimer's disease
    Vargas MG, Havel J, Patocka J
    Ref: Journal of Chromatography A, 802:121, 1998 : PubMed


    Title: Reversal of scopolamine-induced deficits in radial maze performance by (-)-huperzine A: comparison with E2020 and tacrine
    Wang T, Tang XC
    Ref: European Journal of Pharmacology, 349:137, 1998 : PubMed


    Title: Sensitivity of bovine retinal acetylcholinesterase (E.C. toward tacrine: kinetic characterization
    Al-Jafari AA, Kamal MA, Alhomida AS
    Ref: J Biochem Mol Toxicol, 12:245, 1998 : PubMed


    Title: Effects of 9-amino-1,2,3,4-tetrahydroacridine (THA) on ATP diphosphohydrolase (EC and 5'-nucleotidase (EC from rat brain synaptosomes
    Bonan CD, Battastini AM, Schetinger MR, Moreira CM, Frassetto SS, Dias RD, Sarkis JJ
    Ref: General Pharmacology, 28:761, 1997 : PubMed


    Title: Motor dysfunction produced by tacrine administration in rats
    Carriero DL, Outslay G, Mayorga AJ, Aberman J, Gianutsos G, Salamone JD
    Ref: Pharmacol Biochem Behav, 58:851, 1997 : PubMed


    Title: Tremulous jaw movements induced by the acetylcholinesterase inhibitor tacrine: effects of antiparkinsonian drugs
    Cousins MS, Carriero DL, Salamone JD
    Ref: European Journal of Pharmacology, 322:137, 1997 : PubMed


    Title: [Advantages in long-term treatment with Cognex in Alzheimer disease]
    Gracon S, Smith F, Shokry A
    Ref: Schweiz Rundsch Med Prax, 86:1350, 1997 : PubMed


    Title: The effect of several putative cognition enhancers on a water maze acquisition deficit produced by pCPA + scopolamine combination treatment
    Harder JA, Kelly ME
    Ref: Pharmacol Biochem Behav, 56:657, 1997 : PubMed


    Title: The effects of chronic tacrine therapy on d-tubocurarine blockade in the soleus and tibialis muscles of the rat
    Ibebunjo C, Donati F, Fox GS, Eshelby D, Tchervenkov JI
    Ref: Anesthesia & Analgesia, 85:431, 1997 : PubMed


    Title: Combined cholinergic and 5-HT2 receptor activation suppresses thalamocortical oscillations in aged rats
    Jakala P, Riekkinen P, Jr.
    Ref: Pharmacol Biochem Behav, 56:713, 1997 : PubMed


    Title: Effects of NIK-247 on cholinesterase and scopolamine-induced amnesia [published erratum appears in Methods Find Exp Clin Pharmacol 1997 Jun;19(5):364]
    Kojima J, Nakajima K, Ochiai M, Nakayama K
    Ref: Methods Find Exp Clin Pharmacol, 19:245, 1997 : PubMed


    Title: Effects of cholinesterase inhibitors on the secretion of beta-amyloid precursor protein in cell cultures
    Lahiri DK, Farlow MR, Nurnberger JI, Jr., Greig NH
    Ref: Annals of the New York Academy of Sciences, 826:416, 1997 : PubMed


    Title: Alzheimer's disease: an overview for the pharmacist
    McGuffey EC
    Ref: J Am Pharm Assoc, 3:347, 1997 : PubMed


    Title: Prevention of amitriptyline-induced avoidance impairment by tacrine in mice
    Pavone F, Battaglia M, Sansone M
    Ref: Behavioural Brain Research, 89:229, 1997 : PubMed


    Title: Effect of tetrahydroaminoacridine, a cholinesterase inhibitor, on cognitive performance following experimental brain injury
    Pike BR, Hamm RJ, Temple MD, Buck DL, Lyeth BG
    Ref: Journal of Neurotrauma, 14:897, 1997 : PubMed


    Title: Studies on a new series of THA analogues: effects of the aromatic residues that line the gorge of AChE
    Pomponi M, Marta M, Colella A, Sacchi S, Patamia M, Gatta F, Capone F, Oliverio A, Pavone F
    Ref: FEBS Letters, 409:155, 1997 : PubMed


    Title: Metabolic disposition of the cognition activator tacrine in rats, dogs, and humans. Species comparisons
    Pool WF, Reily MD, Bjorge SM, Woolf TF
    Ref: Drug Metabolism & Disposition: The Biological Fate of Chemicals, 25:590, 1997 : PubMed


    Title: Frontal dysfunction blocks the therapeutic effect of THA on attention in Alzheimer's disease
    Riekkinen P, Jr., Riekkinen M, Soininen H, Kuikka J, Laakso M, Riekkinen P, Sr.
    Ref: Neuroreport, 8:1845, 1997 : PubMed


    Title: Enhanced performance of spatial and visual recognition memory tasks by the selective acetylcholinesterase inhibitor E2020 in rhesus monkeys
    Rupniak NM, Tye SJ, Field MJ
    Ref: Psychopharmacology, 131:406, 1997 : PubMed


    Title: Pharmacological basis of drug therapy of Alzheimer's disease
    Sharma A, Parikh V, Singh M
    Ref: Indian J Exp Biol, 35:1146, 1997 : PubMed


    Title: Functional activation of cerebral blood flow abolished by scopolamine is reversed by cognitive enhancers associated with cholinesterase inhibition: a positron emission tomography study in unanesthetized monkeys
    Tsukada H, Kakiuchi T, Ando I, Ouchi Y
    Ref: Journal of Pharmacology & Experimental Therapeutics, 281:1408, 1997 : PubMed


    Title: The effect of cytochromes P4501A induction and inhibition on the disposition of the cognition activator tacrine in rat hepatic preparations
    Bezek S, Kukan M, Pool WF, Woolf TF
    Ref: Xenobiotica, 26:935, 1996 : PubMed


    Title: Huperzine A, a novel promising acetylcholinesterase inhibitor
    Cheng DH, Ren H, Tang XC
    Ref: Neuroreport, 8:97, 1996 : PubMed


    Title: Inhibition of tacrine oral clearance by cimetidine
    Forgue ST, Reece PA, Sedman AJ, deVries TM
    Ref: Clinical Pharmacology & Therapeutics, 59:444, 1996 : PubMed


    Title: An enriched-population, double-blind, placebo-controlled, crossover study of tacrine and lecithin in Alzheimer's disease. The Tacrine 970-6 Study Group
    Foster NL, Petersen RC, Gracon SI, Lewis K
    Ref: Dementia, 7:260, 1996 : PubMed


    Title: Allosteric regulation of the binding of [3H]acetylcholine to m2 muscarinic receptors
    Gnagey AL, Ellis J
    Ref: Biochemical Pharmacology, 52:1767, 1996 : PubMed


    Title: Effects of tacrine (THA) on spatial reference memory and cholinergic enzymes in specific rat brain regions
    Jackson JJ, Soliman MR
    Ref: Life Sciences, 58:47, 1996 : PubMed


    Title: Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis
    Loewenstein-Lichtenstein Y, Glick D, Gluzman N, Sternfeld M, Zakut H, Soreq H
    Ref: Molecular Pharmacology, 50:1423, 1996 : PubMed


    Title: [Pharma-clinics. Drug of the month. Tacrine (Cognex)]
    Scheen AJ
    Ref: Rev Med Liege, 51:379, 1996 : PubMed


    Title: [Alzheimer disease cannot be treated with Cognex]
    Shafazand M
    Ref: Lakartidningen, 93:1406, 1996 : PubMed


    Title: Cholinesterase inhibitors proposed for treating dementia in Alzheimer's disease: selectivity toward human brain acetylcholinesterase compared with butyrylcholinesterase
    Pacheco G, Palacios-Esquivel R, Moss DE
    Ref: Journal of Pharmacology & Experimental Therapeutics, 274:767, 1995 : PubMed


    Title: Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library
    Pirrung MC, Chau JH, Chen J
    Ref: Chemistry & Biology, 2:621, 1995 : PubMed


    Title: [New therapeutic prospects in Alzheimer disease]
    Rouhart F
    Ref: Rev Med Interne, 16:860, 1995 : PubMed


    Title: MKC-231, a choline uptake enhancer, ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice
    Murai S, Saito H, Abe E, Masuda Y, Odashima J, Itoh T
    Ref: Journal of Neural Transmission General Section, 98:1, 1994 : PubMed


    Title: The next generation of cholinesterase inhibitors
    Adem A
    Ref: Acta Neurologica Scandinavica Supplementum, 149:10, 1993 : PubMed


    Title: Changes of rat blood and tissue cholinesterases following administration of tacrine derivatives in vivo
    Bajgar J, Skopec F
    Ref: Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity, 36:73, 1993 : PubMed


    Title: Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex
    Messamore E, Warpman U, Ogane N, Giacobini E
    Ref: Neuropharmacology, 32:745, 1993 : PubMed


    Title: Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors
    Radic Z, Pickering NA, Vellom DC, Camp S, Taylor P
    Ref: Biochemistry, 32:12074, 1993 : PubMed


    Title: In vitro protection of acetylcholinesterase and butyrylcholinesterase by tetrahydroaminoacridine. Comparison with physostigmine
    Galli A, Mori F, Gori I, Lucherini M
    Ref: Biochemical Pharmacology, 43:2427, 1992 : PubMed


    Title: Preferential inhibition of acetylcholinesterase molecular forms in rat brain
    Ogane N, Giacobini E, Messamore E
    Ref: Neurochemical Research, 17:489, 1992 : PubMed


    Title: Effects of tacrine, velnacrine (HP029), suronacrine (HP128), and 3,4-diaminopyridine on skeletal neuromuscular transmission in vitro
    Braga MF, Harvey AL, Rowan EG
    Ref: British Journal of Pharmacology, 102:909, 1991 : PubMed


    Title: Reversibility of the inhibition of acetylcholinesterase by tacrine
    Dawson RM
    Ref: Neuroscience Letters, 118:85, 1990 : PubMed


    Title: The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro
    Hunter AJ, Murray TK, Jones JA, Cross AJ, Green AR
    Ref: British Journal of Pharmacology, 98:79, 1989 : PubMed


    Title: The mechanism of tetrahydroaminoacridine-evoked release of endogenous 5-hydroxytryptamine and dopamine from rat brain tissue prisms
    Robinson TN, De Souza RJ, Cross AJ, Green AR
    Ref: British Journal of Pharmacology, 98:1127, 1989 : PubMed


    Title: Inhibitory effect of 1,2,3,4-tetrahydro-9-aminoacridine on the depolarization-induced release of GABA from cerebral cortex
    de Belleroche J, Gardiner IM
    Ref: British Journal of Pharmacology, 94:1017, 1988 : PubMed


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