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| Title : A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network - Cheng_2022_Acta.Pharmacol.Sin__ |
| Author(s) : Cheng R , Fujinaga M , Yang J , Rong J , Haider A , Ogasawara D , Van RS , Shao T , Chen Z , Zhang X , Calderon Leon ER , Zhang Y , Mori W , Kumata K , Yamasaki T , Xie L , Sun S , Wang L , Ran C , Shao Y , Cravatt B , Josephson L , Zhang MR , Liang SH |
| Ref : Acta Pharmacol Sin , : , 2022 |
| Abstract : Cheng_2022_Acta.Pharmacol.Sin__ |
| ESTHER : Cheng_2022_Acta.Pharmacol.Sin__ |
| PubMedSearch : Cheng_2022_Acta.Pharmacol.Sin__ |
| PubMedID: 35513432 |
| Gene_locus related to this paper: human-MGLL |
| Title : First-in-human in vivo undefined imaging and quantification of monoacylglycerol lipase in the brain: a PET study with (18)F-T-401 - Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ |
| Author(s) : Takahata K , Seki C , Kimura Y , Kubota M , Ichise M , Sano Y , Yamamoto Y , Tagai K , Shimada H , Kitamura S , Matsuoka K , Endo H , Shinotoh H , Kawamura K , Zhang MR , Takado Y , Higuchi M |
| Ref : Eur J Nucl Med Mol Imaging , : , 2022 |
| Abstract : Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ |
| ESTHER : Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ |
| PubMedSearch : Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ |
| PubMedID: 35022846 |
| Gene_locus related to this paper: human-MGLL |
| Title : Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold - Rong_2021_J.Med.Chem__ |
| Author(s) : Rong J , Mori W , Xia X , Schafroth MA , Zhao C , Van RS , Yamasaki T , Chen J , Xiao Z , Haider A , Ogasawara D , Hiraishi A , Shao T , Zhang Y , Chen Z , Pang F , Hu K , Xie L , Fujinaga M , Kumata K , Gou Y , Fang Y , Gu S , Wei H , Bao L , Xu H , Collier TL , Shao Y , Carson RE , Cravatt BF , Wang L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Rong_2021_J.Med.Chem__ |
| ESTHER : Rong_2021_J.Med.Chem__ |
| PubMedSearch : Rong_2021_J.Med.Chem__ |
| PubMedID: 34569803 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping - Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| Author(s) : Chen Z , Mori W , Rong J , Schafroth MA , Shao T , Van RS , Ogasawara D , Yamasaki T , Hiraishi A , Hatori A , Chen J , Zhang Y , Hu K , Fujinaga M , Sun J , Yu Q , Collier TL , Shao Y , Cravatt BF , Josephson L , Zhang MR , Liang SH |
| Ref : Acta Pharm Sin B , 11 :1686 , 2021 |
| Abstract : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| ESTHER : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| PubMedSearch : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| PubMedID: 34221877 |
| Gene_locus related to this paper: human-MGLL |
| Title : Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study - Yamasaki_2021_Theranostics_11_9492 |
| Author(s) : Yamasaki T , Hatori A , Zhang Y , Mori W , Kurihara Y , Ogawa M , Wakizaka H , Rong J , Wang L , Liang S , Zhang MR |
| Ref : Theranostics , 11 :9492 , 2021 |
| Abstract : Yamasaki_2021_Theranostics_11_9492 |
| ESTHER : Yamasaki_2021_Theranostics_11_9492 |
| PubMedSearch : Yamasaki_2021_Theranostics_11_9492 |
| PubMedID: 34646382 |
| Title : Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development - Hou_2021_J.Med.Chem_64_123 |
| Author(s) : Hou L , Rong J , Haider A , Ogasawara D , Varlow C , Schafroth MA , Mu L , Gan J , Xu H , Fowler CJ , Zhang MR , Vasdev N , Ametamey S , Cravatt BF , Wang L , Liang SH |
| Ref : Journal of Medicinal Chemistry , 64 :123 , 2021 |
| Abstract : Hou_2021_J.Med.Chem_64_123 |
| ESTHER : Hou_2021_J.Med.Chem_64_123 |
| PubMedSearch : Hou_2021_J.Med.Chem_64_123 |
| PubMedID: 33379862 |
| Title : Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[(11)C]carboxylate - Mori_2019_Bioorg.Med.Chem_27_3568 |
| Author(s) : Mori W , Hatori A , Zhang Y , Kurihara Y , Yamasaki T , Xie L , Kumata K , Hu K , Fujinaga M , Zhang MR |
| Ref : Bioorganic & Medicinal Chemistry , 27 :3568 , 2019 |
| Abstract : Mori_2019_Bioorg.Med.Chem_27_3568 |
| ESTHER : Mori_2019_Bioorg.Med.Chem_27_3568 |
| PubMedSearch : Mori_2019_Bioorg.Med.Chem_27_3568 |
| PubMedID: 31278005 |
| Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336 |
| Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019 |
| Abstract : Chen_2019_J.Med.Chem_62_3336 |
| ESTHER : Chen_2019_J.Med.Chem_62_3336 |
| PubMedSearch : Chen_2019_J.Med.Chem_62_3336 |
| PubMedID: 30829483 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase - Hattori_2019_J.Med.Chem_62_2362 |
| Author(s) : Hattori Y , Aoyama K , Maeda J , Arimura N , Takahashi Y , Sasaki M , Fujinaga M , Seki C , Nagai Y , Kawamura K , Yamasaki T , Zhang MR , Higuchi M , Koike T |
| Ref : Journal of Medicinal Chemistry , 62 :2362 , 2019 |
| Abstract : Hattori_2019_J.Med.Chem_62_2362 |
| ESTHER : Hattori_2019_J.Med.Chem_62_2362 |
| PubMedSearch : Hattori_2019_J.Med.Chem_62_2362 |
| PubMedID: 30753069 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes - Chen_2019_J.Med.Chem_62_8866 |
| Author(s) : Chen Z , Mori W , Fu H , Schafroth MA , Hatori A , Shao T , Zhang G , Van RS , Zhang Y , Hu K , Fujinaga M , Wang L , Belov V , Ogasawara D , Giffenig P , Deng X , Rong J , Yu Q , Zhang X , Papisov MI , Shao Y , Collier TL , Ma JA , Cravatt BF , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :8866 , 2019 |
| Abstract : Chen_2019_J.Med.Chem_62_8866 |
| ESTHER : Chen_2019_J.Med.Chem_62_8866 |
| PubMedSearch : Chen_2019_J.Med.Chem_62_8866 |
| PubMedID: 31518130 |
| Title : Aspirin Attenuates the Bioactivation of and Platelet Response to Vicagrel in Mice - Jia_2018_J.Cardiovasc.Pharmacol_72_252 |
| Author(s) : Jia YM , Gu TT , Ji JZ , Tai T , Zhang MR , Huang BB , Zhou H , Mi QY , Xie HG |
| Ref : J Cardiovasc Pharmacol , 72 :252 , 2018 |
| Abstract : Jia_2018_J.Cardiovasc.Pharmacol_72_252 |
| ESTHER : Jia_2018_J.Cardiovasc.Pharmacol_72_252 |
| PubMedSearch : Jia_2018_J.Cardiovasc.Pharmacol_72_252 |
| PubMedID: 30358688 |
| Title : First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [(11)C]SAR127303 - Yamasaki_2018_Neuroimage_176_313 |
| Author(s) : Yamasaki T , Mori W , Zhang Y , Hatori A , Fujinaga M , Wakizaka H , Kurihara Y , Wang L , Nengaki N , Ohya T , Liang SH , Zhang MR |
| Ref : Neuroimage , 176 :313 , 2018 |
| Abstract : Yamasaki_2018_Neuroimage_176_313 |
| ESTHER : Yamasaki_2018_Neuroimage_176_313 |
| PubMedSearch : Yamasaki_2018_Neuroimage_176_313 |
| PubMedID: 29738910 |
| Title : Voxel-Based Acetylcholinesterase PET Study in Early and Late Onset Alzheimer's Disease - Hirano_2018_J.Alzheimers.Dis_62_1539 |
| Author(s) : Hirano S , Shinotoh H , Shimada H , Ota T , Sato K , Tanaka N , Zhang MR , Higuchi M , Fukushi K , Irie T , Kuwabara S , Suhara T |
| Ref : J Alzheimers Dis , 62 :1539 , 2018 |
| Abstract : Hirano_2018_J.Alzheimers.Dis_62_1539 |
| ESTHER : Hirano_2018_J.Alzheimers.Dis_62_1539 |
| PubMedSearch : Hirano_2018_J.Alzheimers.Dis_62_1539 |
| PubMedID: 29562505 |
| Title : Human UGT2B7 is the major isoform responsible for the glucuronidation of clopidogrel carboxylate - Ji_2018_Biopharm.Drug.Dispos_39_88 |
| Author(s) : Ji JZ , Huang BB , Gu TT , Tai T , Zhou H , Jia YM , Mi QY , Zhang MR , Xie HG |
| Ref : Biopharmaceutics & Drug Disposition , 39 :88 , 2018 |
| Abstract : Ji_2018_Biopharm.Drug.Dispos_39_88 |
| ESTHER : Ji_2018_Biopharm.Drug.Dispos_39_88 |
| PubMedSearch : Ji_2018_Biopharm.Drug.Dispos_39_88 |
| PubMedID: 29240983 |
| Title : In Vitro and in Vivo Evaluation of (11)C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies - Cheng_2018_J.Med.Chem_61_2278 |
| Author(s) : Cheng R , Mori W , Ma L , Alhouayek M , Hatori A , Zhang Y , Ogasawara D , Yuan G , Chen Z , Zhang X , Shi H , Yamasaki T , Xie L , Kumata K , Fujinaga M , Nagai Y , Minamimoto T , Svensson M , Wang L , Du Y , Ondrechen MJ , Vasdev N , Cravatt BF , Fowler C , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 61 :2278 , 2018 |
| Abstract : Cheng_2018_J.Med.Chem_61_2278 |
| ESTHER : Cheng_2018_J.Med.Chem_61_2278 |
| PubMedSearch : Cheng_2018_J.Med.Chem_61_2278 |
| PubMedID: 29481079 |
| Title : Dementia with Lewy bodies can be well-differentiated from Alzheimer's disease by measurement of brain acetylcholinesterase activity-a [(11) C]MP4A PET study - Shimada_2015_Int.J.Geriatr.Psychiatry_30_1105 |
| Author(s) : Shimada H , Hirano S , Sinotoh H , Ota T , Tanaka N , Sato K , Yamada M , Fukushi K , Irie T , Zhang MR , Higuchi M , Kuwabara S , Suhara T |
| Ref : Int J Geriatr Psychiatry , 30 :1105 , 2015 |
| Abstract : Shimada_2015_Int.J.Geriatr.Psychiatry_30_1105 |
| ESTHER : Shimada_2015_Int.J.Geriatr.Psychiatry_30_1105 |
| PubMedSearch : Shimada_2015_Int.J.Geriatr.Psychiatry_30_1105 |
| PubMedID: 26280153 |
| Title : PET probes for imaging brain acetylcholinesterase - Kikuchi_2013_J.Labelled.Comp.Radiopharm_56_172 |
| Author(s) : Kikuchi T , Okamura T , Zhang MR , Irie T |
| Ref : J Labelled Comp Radiopharm , 56 :172 , 2013 |
| Abstract : Kikuchi_2013_J.Labelled.Comp.Radiopharm_56_172 |
| ESTHER : Kikuchi_2013_J.Labelled.Comp.Radiopharm_56_172 |
| PubMedSearch : Kikuchi_2013_J.Labelled.Comp.Radiopharm_56_172 |
| PubMedID: 24285323 |
| Title : A method to predict the ratio of the tracer conversion rate to the tracer back-diffusion rate of an irreversible-type radiotracer in humans by preclinical evaluations - Ohya_2012_Nucl.Med.Commun_33_1019 |
| Author(s) : Ohya T , Zhang MR , Fukumura T , Fukushi K , Kikuchi T , Irie T |
| Ref : Nucl Med Commun , 33 :1019 , 2012 |
| Abstract : Ohya_2012_Nucl.Med.Commun_33_1019 |
| ESTHER : Ohya_2012_Nucl.Med.Commun_33_1019 |
| PubMedSearch : Ohya_2012_Nucl.Med.Commun_33_1019 |
| PubMedID: 22850605 |
| Title : Effect of radiolabeled metabolite elimination from the brain on the accuracy of cerebral enzyme activity estimation using positron emission tomography with substrate tracers - Ohya_2011_Neuroimage_56_1105 |
| Author(s) : Ohya T , Okamura T , Nagai Y , Fukushi K , Irie T , Suhara T , Zhang MR , Fukumura T , Kikuchi T |
| Ref : Neuroimage , 56 :1105 , 2011 |
| Abstract : Ohya_2011_Neuroimage_56_1105 |
| ESTHER : Ohya_2011_Neuroimage_56_1105 |
| PubMedSearch : Ohya_2011_Neuroimage_56_1105 |
| PubMedID: 21324368 |
| Title : In vivo evaluation of N-[18F]fluoroethylpiperidin-4ylmethyl acetate in rats compared with MP4A as a probe for measuring cerebral acetylcholinesterase activity - Kikuchi_2010_Synapse_64_209 |
| Author(s) : Kikuchi T , Okamura T , Zhang MR , Fukushi K , Irie T |
| Ref : Synapse , 64 :209 , 2010 |
| Abstract : Kikuchi_2010_Synapse_64_209 |
| ESTHER : Kikuchi_2010_Synapse_64_209 |
| PubMedSearch : Kikuchi_2010_Synapse_64_209 |
| PubMedID: 19862687 |
| Title : Cerebral acetylcholinesterase imaging: development of the radioprobes - Kikuchi_2007_Curr.Top.Med.Chem_7_1790 |
| Author(s) : Kikuchi T , Okamura T , Fukushi K , Takahashi K , Toyohara J , Okada M , Zhang MR , Irie T |
| Ref : Curr Top Med Chem , 7 :1790 , 2007 |
| Abstract : Kikuchi_2007_Curr.Top.Med.Chem_7_1790 |
| ESTHER : Kikuchi_2007_Curr.Top.Med.Chem_7_1790 |
| PubMedSearch : Kikuchi_2007_Curr.Top.Med.Chem_7_1790 |
| PubMedID: 17979787 |
| Title : N-[18F] fluoroethylpiperidin-4ylmethyl acetate, a novel lipophilic acetylcholine analogue for PET measurement of brain acetylcholinesterase activity - Kikuchi_2005_J.Med.Chem_48_2577 |
| Author(s) : Kikuchi T , Zhang MR , Ikota N , Fukushi K , Okamura T , Suzuki K , Arano Y , Irie T |
| Ref : Journal of Medicinal Chemistry , 48 :2577 , 2005 |
| Abstract : Kikuchi_2005_J.Med.Chem_48_2577 |
| ESTHER : Kikuchi_2005_J.Med.Chem_48_2577 |
| PubMedSearch : Kikuchi_2005_J.Med.Chem_48_2577 |
| PubMedID: 15801847 |
| Title : N-[18F]fluoroethylpiperidin-4-ylmethyl butyrate: a novel radiotracer for quantifying brain butyrylcholinesterase activity by positron emission tomography - Kikuchi_2004_Bioorg.Med.Chem.Lett_14_1927 |
| Author(s) : Kikuchi T , Zhang MR , Ikota N , Fukushi K , Okamura T , Suzuki K , Arano Y , Irie T |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1927 , 2004 |
| Abstract : Kikuchi_2004_Bioorg.Med.Chem.Lett_14_1927 |
| ESTHER : Kikuchi_2004_Bioorg.Med.Chem.Lett_14_1927 |
| PubMedSearch : Kikuchi_2004_Bioorg.Med.Chem.Lett_14_1927 |
| PubMedID: 15050629 |
| Title : N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo - Zhang_2003_Bioorg.Med.Chem_11_2519 |
| Author(s) : Zhang MR , Furutsuka K , Maeda J , Kikuchi T , Kida T , Okauchi T , Irie T , Suzuki K |
| Ref : Bioorganic & Medicinal Chemistry , 11 :2519 , 2003 |
| Abstract : Zhang_2003_Bioorg.Med.Chem_11_2519 |
| ESTHER : Zhang_2003_Bioorg.Med.Chem_11_2519 |
| PubMedSearch : Zhang_2003_Bioorg.Med.Chem_11_2519 |
| PubMedID: 12757720 |
| Title : Synthesis and preliminary evaluation of [18F]FEtP4A, a promising PET tracer for mapping acetylcholinesterase in vivo - Zhang_2002_Nucl.Med.Biol_29_463 |
| Author(s) : Zhang MR , Tsuchiyama A , Haradahira T , Furutsuka K , Yoshida Y , Kida T , Noguchi J , Irie T , Suzuki K |
| Ref : Nucl Med Biol , 29 :463 , 2002 |
| Abstract : Zhang_2002_Nucl.Med.Biol_29_463 |
| ESTHER : Zhang_2002_Nucl.Med.Biol_29_463 |
| PubMedSearch : Zhang_2002_Nucl.Med.Biol_29_463 |
| PubMedID: 12031881 |