Full name : Zaagsma Johan
First name : Johan
Mail : Dept of Molecular Pharmacology, University of Groningen, Groningen
Zip Code :
City :
Country : The Netherlands
Email :
Phone :
Fax :
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Directory :
| Title : Muscarinic receptors on airway mesenchymal cells: novel findings for an ancient target - Meurs_2013_Pulm.Pharmacol.Ther_26_145 |
| Author(s) : Meurs H , Dekkers BG , Maarsingh H , Halayko AJ , Zaagsma J , Gosens R |
| Ref : Pulm Pharmacol Ther , 26 :145 , 2013 |
| Abstract : Meurs_2013_Pulm.Pharmacol.Ther_26_145 |
| ESTHER : Meurs_2013_Pulm.Pharmacol.Ther_26_145 |
| PubMedSearch : Meurs_2013_Pulm.Pharmacol.Ther_26_145 |
| PubMedID: 22842340 |
| Title : Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD - Pera_2011_Eur.Respir.J_38_789 |
| Author(s) : Pera T , Zuidhof A , Valadas J , Smit M , Schoemaker RG , Gosens R , Maarsingh H , Zaagsma J , Meurs H |
| Ref : Eur Respir J , 38 :789 , 2011 |
| Abstract : Pera_2011_Eur.Respir.J_38_789 |
| ESTHER : Pera_2011_Eur.Respir.J_38_789 |
| PubMedSearch : Pera_2011_Eur.Respir.J_38_789 |
| PubMedID: 21349917 |
| Title : Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison - Bos_2007_Eur.Respir.J_30_653 |
| Author(s) : Bos IS , Gosens R , Zuidhof AB , Schaafsma D , Halayko AJ , Meurs H , Zaagsma J |
| Ref : Eur Respir J , 30 :653 , 2007 |
| Abstract : Bos_2007_Eur.Respir.J_30_653 |
| ESTHER : Bos_2007_Eur.Respir.J_30_653 |
| PubMedSearch : Bos_2007_Eur.Respir.J_30_653 |
| PubMedID: 17537779 |
| Title : Muscarinic receptor signaling in the pathophysiology of asthma and COPD - Gosens_2006_Respir.Res_7_73 |
| Author(s) : Gosens R , Zaagsma J , Meurs H , Halayko AJ |
| Ref : Respir Res , 7 :73 , 2006 |
| Abstract : Gosens_2006_Respir.Res_7_73 |
| ESTHER : Gosens_2006_Respir.Res_7_73 |
| PubMedSearch : Gosens_2006_Respir.Res_7_73 |
| PubMedID: 16684353 |
| Title : Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling - Gosens_2005_Am.J.Respir.Crit.Care.Med_171_1096 |
| Author(s) : Gosens R , Bos IS , Zaagsma J , Meurs H |
| Ref : American Journal of Respiratory & Critical Care Medicine , 171 :1096 , 2005 |
| Abstract : Gosens_2005_Am.J.Respir.Crit.Care.Med_171_1096 |
| ESTHER : Gosens_2005_Am.J.Respir.Crit.Care.Med_171_1096 |
| PubMedSearch : Gosens_2005_Am.J.Respir.Crit.Care.Med_171_1096 |
| PubMedID: 15695490 |
| Title : Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation - Maarsingh_2005_Respir.Res_6_23 |
| Author(s) : Maarsingh H , Tio MA , Zaagsma J , Meurs H |
| Ref : Respir Res , 6 :23 , 2005 |
| Abstract : Maarsingh_2005_Respir.Res_6_23 |
| ESTHER : Maarsingh_2005_Respir.Res_6_23 |
| PubMedSearch : Maarsingh_2005_Respir.Res_6_23 |
| PubMedID: 15748286 |
| Title : Acetylcholine: a novel regulator of airway smooth muscle remodelling? - Gosens_2004_Eur.J.Pharmacol_500_193 |
| Author(s) : Gosens R , Zaagsma J , Grootte Bromhaar M , Nelemans A , Meurs H |
| Ref : European Journal of Pharmacology , 500 :193 , 2004 |
| Abstract : Gosens_2004_Eur.J.Pharmacol_500_193 |
| ESTHER : Gosens_2004_Eur.J.Pharmacol_500_193 |
| PubMedSearch : Gosens_2004_Eur.J.Pharmacol_500_193 |
| PubMedID: 15464033 |
| Title : Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle - Gosens_2003_Am.J.Respir.Cell.Mol.Biol_28_257 |
| Author(s) : Gosens R , Nelemans SA , Grootte Bromhaar MM , McKay S , Zaagsma J , Meurs H |
| Ref : American Journal of Respiratory Cellular & Molecular Biology , 28 :257 , 2003 |
| Abstract : Gosens_2003_Am.J.Respir.Cell.Mol.Biol_28_257 |
| ESTHER : Gosens_2003_Am.J.Respir.Cell.Mol.Biol_28_257 |
| PubMedSearch : Gosens_2003_Am.J.Respir.Cell.Mol.Biol_28_257 |
| PubMedID: 12540494 |
| Title : Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity - Meurs_2000_Br.J.Pharmacol_130_1793 |
| Author(s) : Meurs H , Hamer MA , Pethe S , Vadon-Le Goff S , Boucher JL , Zaagsma J |
| Ref : British Journal of Pharmacology , 130 :1793 , 2000 |
| Abstract : Meurs_2000_Br.J.Pharmacol_130_1793 |
| ESTHER : Meurs_2000_Br.J.Pharmacol_130_1793 |
| PubMedSearch : Meurs_2000_Br.J.Pharmacol_130_1793 |
| PubMedID: 10952667 |
| Title : Effects of endogenous superoxide anion and nitric oxide on cholinergic constriction of normal and hyperreactive guinea pig airways - De Boer_1998_Am.J.Respir.Crit.Care.Med_158_1784 |
| Author(s) : De Boer J , Pouw FM , Zaagsma J , Meurs H |
| Ref : American Journal of Respiratory & Critical Care Medicine , 158 :1784 , 1998 |
| Abstract : De Boer_1998_Am.J.Respir.Crit.Care.Med_158_1784 |
| ESTHER : De Boer_1998_Am.J.Respir.Crit.Care.Med_158_1784 |
| PubMedSearch : De Boer_1998_Am.J.Respir.Crit.Care.Med_158_1784 |
| PubMedID: 9847268 |
| Title : Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea-pig lung strip and inhibition of acetylcholine release in the guinea-pig trachea with the selective muscarinic receptor antagonist tripitramine - Roffel_1997_Br.J.Pharmacol_122_133 |
| Author(s) : Roffel AF , Davids JH , Elzinga CR , Wolf D , Zaagsma J , Kilbinger H |
| Ref : British Journal of Pharmacology , 122 :133 , 1997 |
| Abstract : Roffel_1997_Br.J.Pharmacol_122_133 |
| ESTHER : Roffel_1997_Br.J.Pharmacol_122_133 |
| PubMedSearch : Roffel_1997_Br.J.Pharmacol_122_133 |
| PubMedID: 9298539 |
| Title : Poster: No involvement of M2 type receptors in direct contraction of guinea pig tracheal smooth muscle - |
| Author(s) : Roffel AF , Elzinga CR , Zaagsma J |
| Ref : Life Sciences , 60 :1192 , 1997 |
| PubMedID: |
| Title : Poster: Characterization of prejunctional inhibitory muscarinic autoreceptors in guinea pig trachea using tripitramine - |
| Author(s) : Zaagsma J , Roffel AF , Davids JH , Elzinga CR , Kilbinger H |
| Ref : Life Sciences , 60 :1195 , 1997 |
| PubMedID: |
| Title : Muscarinic control of airway function - Zaagsma_1997_Life.Sci_60(13-14)_1061 |
| Author(s) : Zaagsma J , Roffel AF , Meurs H |
| Ref : Life Sciences , 60 :1061 , 1997 |
| Abstract : Zaagsma_1997_Life.Sci_60(13-14)_1061 |
| ESTHER : Zaagsma_1997_Life.Sci_60(13-14)_1061 |
| PubMedSearch : Zaagsma_1997_Life.Sci_60(13-14)_1061 |
| PubMedID: 9121348 |
| Title : No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea - Roffel_1995_Br.J.Pharmacol_115_665 |
| Author(s) : Roffel AF , Meurs H , Elzinga CR , Zaagsma J |
| Ref : British Journal of Pharmacology , 115 :665 , 1995 |
| Abstract : Roffel_1995_Br.J.Pharmacol_115_665 |
| ESTHER : Roffel_1995_Br.J.Pharmacol_115_665 |
| PubMedSearch : Roffel_1995_Br.J.Pharmacol_115_665 |
| PubMedID: 7582488 |
| Title : Contribution of a cholinergic reflex mechanism to allergen-induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea-pigs - Santing_1995_Br.J.Pharmacol_114_414 |
| Author(s) : Santing RE , Pasman Y , Olymulder CG , Roffel AF , Meurs H , Zaagsma J |
| Ref : British Journal of Pharmacology , 114 :414 , 1995 |
| Abstract : Santing_1995_Br.J.Pharmacol_114_414 |
| ESTHER : Santing_1995_Br.J.Pharmacol_114_414 |
| PubMedSearch : Santing_1995_Br.J.Pharmacol_114_414 |
| PubMedID: 7881742 |
| Title : Selectivity profile of some recent muscarinic antagonists in bovine and guinea-pig trachea and heart - Roffel_1994_Arch.Int.Pharmacodyn.Ther_328_82 |
| Author(s) : Roffel AF , Hamstra JJ , Elzinga CR , Zaagsma J |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 328 :82 , 1994 |
| Abstract : Roffel_1994_Arch.Int.Pharmacodyn.Ther_328_82 |
| ESTHER : Roffel_1994_Arch.Int.Pharmacodyn.Ther_328_82 |
| PubMedSearch : Roffel_1994_Arch.Int.Pharmacodyn.Ther_328_82 |
| PubMedID: 7893193 |
| Title : Muscarinic M2 receptors do not participate in the functional antagonism between methacholine and isoprenaline in guinea pig tracheal smooth muscle - Roffel_1993_Eur.J.Pharmacol_249_235 |
| Author(s) : Roffel AF , Meurs H , Elzinga CR , Zaagsma J |
| Ref : European Journal of Pharmacology , 249 :235 , 1993 |
| Abstract : Roffel_1993_Eur.J.Pharmacol_249_235 |
| ESTHER : Roffel_1993_Eur.J.Pharmacol_249_235 |
| PubMedSearch : Roffel_1993_Eur.J.Pharmacol_249_235 |
| PubMedID: 8287906 |
| Title : Lack of coupling of muscarinic receptors to phosphoinositide metabolism and adenylyl cyclase in human lymphocytes and polymorphonuclear leukocytes: studies in healthy subjects and allergic asthmatic patients - Meurs_1993_Int.Arch.Allergy.Immunol_100_19 |
| Author(s) : Meurs H , Timmermans A , de Monchy JG , Zaagsma J , Kauffman HF |
| Ref : Int Arch Allergy Immunol , 100 :19 , 1993 |
| Abstract : Meurs_1993_Int.Arch.Allergy.Immunol_100_19 |
| ESTHER : Meurs_1993_Int.Arch.Allergy.Immunol_100_19 |
| PubMedSearch : Meurs_1993_Int.Arch.Allergy.Immunol_100_19 |
| PubMedID: 8381316 |
| Title : Positive cooperative interaction of quaternary anticholinergics with functional muscarinic receptors in bovine tracheal smooth muscle - Roffel_1991_Naunyn.Schmiedebergs.Arch.Pharmacol_343_252 |
| Author(s) : Roffel AF , Elzinga CR , Beltman W , van Tintelen EJ , Zaagsma J |
| Ref : Naunyn Schmiedebergs Arch Pharmacol , 343 :252 , 1991 |
| Abstract : Roffel_1991_Naunyn.Schmiedebergs.Arch.Pharmacol_343_252 |
| ESTHER : Roffel_1991_Naunyn.Schmiedebergs.Arch.Pharmacol_343_252 |
| PubMedSearch : Roffel_1991_Naunyn.Schmiedebergs.Arch.Pharmacol_343_252 |
| PubMedID: 1865928 |
| Title : Heterogeneous receptor binding of classical quaternary muscarinic antagonists. II. Modulation in bovine brain - Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_105 |
| Author(s) : Roffel AF , Ensing K , Elzinga CR , in 't Hout WG , van Tintelen EJ , de Zeeuw RA , Zaagsma J |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 314 :105 , 1991 |
| Abstract : Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_105 |
| ESTHER : Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_105 |
| PubMedSearch : Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_105 |
| PubMedID: 1824185 |
| Title : Heterogeneous receptor binding of classical quaternary muscarinic antagonists. I. Bovine tissue distribution - Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_90 |
| Author(s) : Roffel AF , Ensing K , in 't Hout WG , de Zeeuw RA , Zaagsma J |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 314 :90 , 1991 |
| Abstract : Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_90 |
| ESTHER : Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_90 |
| PubMedSearch : Roffel_1991_Arch.Int.Pharmacodyn.Ther_314_90 |
| PubMedID: 1824191 |
| Title : Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle - Roffel_1990_Pulm.Pharmacol_3_47 |
| Author(s) : Roffel AF , Elzinga CR , Zaagsma J |
| Ref : Pulm Pharmacol , 3 :47 , 1990 |
| Abstract : Roffel_1990_Pulm.Pharmacol_3_47 |
| ESTHER : Roffel_1990_Pulm.Pharmacol_3_47 |
| PubMedSearch : Roffel_1990_Pulm.Pharmacol_3_47 |
| PubMedID: 2152027 |
| Title : Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle - Roffel_1990_Br.J.Pharmacol_99_293 |
| Author(s) : Roffel AF , Meurs H , Elzinga CR , Zaagsma J |
| Ref : British Journal of Pharmacology , 99 :293 , 1990 |
| Abstract : Roffel_1990_Br.J.Pharmacol_99_293 |
| ESTHER : Roffel_1990_Br.J.Pharmacol_99_293 |
| PubMedSearch : Roffel_1990_Br.J.Pharmacol_99_293 |
| PubMedID: 2158372 |
| Title : Poster: Interaction of quaternary anticholinergics with muscarinic receptors in bovine guinea pig and human airway smooth muscle - |
| Author(s) : Roffel AF , Elzinga CR , Beitman W , van Tintelen EJ , Zaagsma J |
| Ref : Trends in Pharmacological Sciences , Suppl :112 , 1989 |
| PubMedID: |
| Title : Allosteric interactions of three muscarine antagonists at bovine tracheal smooth muscle and cardiac M2 receptors - Roffel_1989_Eur.J.Pharmacol_172_61 |
| Author(s) : Roffel AF , Elzinga CR , Meurs H , Zaagsma J |
| Ref : European Journal of Pharmacology , 172 :61 , 1989 |
| Abstract : Roffel_1989_Eur.J.Pharmacol_172_61 |
| ESTHER : Roffel_1989_Eur.J.Pharmacol_172_61 |
| PubMedSearch : Roffel_1989_Eur.J.Pharmacol_172_61 |
| PubMedID: 2714370 |
| Title : Muscarinic receptors in human airway smooth muscle are coupled to phosphoinositide metabolism - Meurs_1989_Eur.J.Pharmacol_164_369 |
| Author(s) : Meurs H , Timmermans A , Van Amsterdam RG , Brouwer F , Kauffman HF , Zaagsma J |
| Ref : European Journal of Pharmacology , 164 :369 , 1989 |
| Abstract : Meurs_1989_Eur.J.Pharmacol_164_369 |
| ESTHER : Meurs_1989_Eur.J.Pharmacol_164_369 |
| PubMedSearch : Meurs_1989_Eur.J.Pharmacol_164_369 |
| PubMedID: 2547640 |
| Title : Poster: Pharmacological and biochemical characterization of muscarinic receotors in human airway smooth muscle - |
| Author(s) : Zaagsma J , Meurs H , Timmermans A , Elzinga CR , Roffel AF |
| Ref : Trends in Pharmacological Sciences , Suppl :108 , 1989 |
| PubMedID: |
| Title : Muscarinic M2 receptors in bovine tracheal smooth muscle: discrepancies between binding and function - Roffel_1988_Eur.J.Pharmacol_153_73 |
| Author(s) : Roffel AF , Elzinga CR , Van Amsterdam RG , de Zeeuw RA , Zaagsma J |
| Ref : European Journal of Pharmacology , 153 :73 , 1988 |
| Abstract : Roffel_1988_Eur.J.Pharmacol_153_73 |
| ESTHER : Roffel_1988_Eur.J.Pharmacol_153_73 |
| PubMedSearch : Roffel_1988_Eur.J.Pharmacol_153_73 |
| PubMedID: 3215279 |
| Title : Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists - Meurs_1988_Eur.J.Pharmacol_156_271 |
| Author(s) : Meurs H , Roffel AF , Postema JB , Timmermans A , Elzinga CR , Kauffman HF , Zaagsma J |
| Ref : European Journal of Pharmacology , 156 :271 , 1988 |
| Abstract : Meurs_1988_Eur.J.Pharmacol_156_271 |
| ESTHER : Meurs_1988_Eur.J.Pharmacol_156_271 |
| PubMedSearch : Meurs_1988_Eur.J.Pharmacol_156_271 |
| PubMedID: 2467823 |