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| Title : Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models - Matsukawa_2023_JCI.Insight_8__e161282 |
| Author(s) : Matsukawa T , Yagi T , Uchida T , Sakai M , Mitsushima M , Naganuma T , Yano H , Inaba Y , Inoue H , Yanagida K , Uematsu M , Nakao K , Nakao H , Aiba A , Nagashima Y , Kubota T , Kubota N , Izumida Y , Yahagi N , Unoki-Kubota H , Kaburagi Y , Asahara SI , Kido Y , Shindou H , Itoh M , Ogawa Y , Minami S , Terauchi Y , Tobe K , Ueki K , Kasuga M , Matsumoto M |
| Ref : JCI Insight , 8 : , 2023 |
| Abstract : Matsukawa_2023_JCI.Insight_8__e161282 |
| ESTHER : Matsukawa_2023_JCI.Insight_8__e161282 |
| PubMedSearch : Matsukawa_2023_JCI.Insight_8__e161282 |
| PubMedID: 37681411 |
| Gene_locus related to this paper: human-FASN , mouse-FASN |
| Title : Role of Hormone-sensitive Lipase in Leptin-Promoted Fat Loss and Glucose Lowering - Takanashi_2017_J.Atheroscler.Thromb_24_1105 |
| Author(s) : Takanashi M , Taira Y , Okazaki S , Takase S , Kimura T , Li CC , Xu PF , Noda A , Sakata I , Kumagai H , Ikeda Y , Iizuka Y , Yahagi N , Shimano H , Osuga JI , Ishibashi S , Kadowaki T , Okazaki H |
| Ref : J Atheroscler Thromb , 24 :1105 , 2017 |
| Abstract : Takanashi_2017_J.Atheroscler.Thromb_24_1105 |
| ESTHER : Takanashi_2017_J.Atheroscler.Thromb_24_1105 |
| PubMedSearch : Takanashi_2017_J.Atheroscler.Thromb_24_1105 |
| PubMedID: 28413180 |
| Title : Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement - Ohta_2011_Biochem.Biophys.Res.Commun_404_254 |
| Author(s) : Ohta K , Sekiya M , Uozaki H , Igarashi M , Takase S , Kumagai M , Takanashi M , Takeuchi Y , Izumida Y , Kubota M , Nishi M , Okazaki H , Iizuka Y , Yahagi N , Yagyu H , Fukayama M , Kadowaki T , Ohashi K , Ishibashi S , Osuga J |
| Ref : Biochemical & Biophysical Research Communications , 404 :254 , 2011 |
| Abstract : Ohta_2011_Biochem.Biophys.Res.Commun_404_254 |
| ESTHER : Ohta_2011_Biochem.Biophys.Res.Commun_404_254 |
| PubMedSearch : Ohta_2011_Biochem.Biophys.Res.Commun_404_254 |
| PubMedID: 21111707 |
| Gene_locus related to this paper: human-LIPE , human-NCEH1 |
| Title : Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis - Sekiya_2009_Cell.Metab_10_219 |
| Author(s) : Sekiya M , Osuga J , Nagashima S , Ohshiro T , Igarashi M , Okazaki H , Takahashi M , Tazoe F , Wada T , Ohta K , Takanashi M , Kumagai M , Nishi M , Takase S , Yahagi N , Yagyu H , Ohashi K , Nagai R , Kadowaki T , Furukawa Y , Ishibashi S |
| Ref : Cell Metab , 10 :219 , 2009 |
| Abstract : Sekiya_2009_Cell.Metab_10_219 |
| ESTHER : Sekiya_2009_Cell.Metab_10_219 |
| PubMedSearch : Sekiya_2009_Cell.Metab_10_219 |
| PubMedID: 19723498 |
| Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1 |
| Title : Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages - Okazaki_2008_J.Biol.Chem_283_33357 |
| Author(s) : Okazaki H , Igarashi M , Nishi M , Sekiya M , Tajima M , Takase S , Takanashi M , Ohta K , Tamura Y , Okazaki S , Yahagi N , Ohashi K , Amemiya-Kudo M , Nakagawa Y , Nagai R , Kadowaki T , Osuga J , Ishibashi S |
| Ref : Journal of Biological Chemistry , 283 :33357 , 2008 |
| Abstract : Okazaki_2008_J.Biol.Chem_283_33357 |
| ESTHER : Okazaki_2008_J.Biol.Chem_283_33357 |
| PubMedSearch : Okazaki_2008_J.Biol.Chem_283_33357 |
| PubMedID: 18782767 |
| Gene_locus related to this paper: human-NCEH1 |
| Title : Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis - Sekiya_2008_J.Lipid.Res_49_1829 |
| Author(s) : Sekiya M , Osuga J , Yahagi N , Okazaki H , Tamura Y , Igarashi M , Takase S , Harada K , Okazaki S , Iizuka Y , Ohashi K , Yagyu H , Okazaki M , Gotoda T , Nagai R , Kadowaki T , Shimano H , Yamada N , Ishibashi S |
| Ref : J Lipid Res , 49 :1829 , 2008 |
| Abstract : Sekiya_2008_J.Lipid.Res_49_1829 |
| ESTHER : Sekiya_2008_J.Lipid.Res_49_1829 |
| PubMedSearch : Sekiya_2008_J.Lipid.Res_49_1829 |
| PubMedID: 18480494 |
| Title : Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis - Okazaki_2006_Diabetes_55_2091 |
| Author(s) : Okazaki H , Igarashi M , Nishi M , Tajima M , Sekiya M , Okazaki S , Yahagi N , Ohashi K , Tsukamoto K , Amemiya-Kudo M , Matsuzaka T , Shimano H , Yamada N , Aoki J , Morikawa R , Takanezawa Y , Arai H , Nagai R , Kadowaki T , Osuga J , Ishibashi S |
| Ref : Diabetes , 55 :2091 , 2006 |
| Abstract : Okazaki_2006_Diabetes_55_2091 |
| ESTHER : Okazaki_2006_Diabetes_55_2091 |
| PubMedSearch : Okazaki_2006_Diabetes_55_2091 |
| PubMedID: 16804080 |
| Title : Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob\/ob mice - Sekiya_2004_J.Biol.Chem_279_15084 |
| Author(s) : Sekiya M , Osuga J , Okazaki H , Yahagi N , Harada K , Shen WJ , Tamura Y , Tomita S , Iizuka Y , Ohashi K , Okazaki M , Sata M , Nagai R , Fujita T , Shimano H , Kraemer FB , Yamada N , Ishibashi S |
| Ref : Journal of Biological Chemistry , 279 :15084 , 2004 |
| Abstract : Sekiya_2004_J.Biol.Chem_279_15084 |
| ESTHER : Sekiya_2004_J.Biol.Chem_279_15084 |
| PubMedSearch : Sekiya_2004_J.Biol.Chem_279_15084 |
| PubMedID: 14752112 |
| Title : Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)\/Lep(ob) mice - Yahagi_2002_J.Biol.Chem_277_19353 |
| Author(s) : Yahagi N , Shimano H , Hasty AH , Matsuzaka T , Ide T , Yoshikawa T , Amemiya-Kudo M , Tomita S , Okazaki H , Tamura Y , Iizuka Y , Ohashi K , Osuga J , Harada K , Gotoda T , Nagai R , Ishibashi S , Yamada N |
| Ref : Journal of Biological Chemistry , 277 :19353 , 2002 |
| Abstract : Yahagi_2002_J.Biol.Chem_277_19353 |
| ESTHER : Yahagi_2002_J.Biol.Chem_277_19353 |
| PubMedSearch : Yahagi_2002_J.Biol.Chem_277_19353 |
| PubMedID: 11923308 |
| Title : Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity - Osuga_2000_Proc.Natl.Acad.Sci.U.S.A_97_787 |
| Author(s) : Osuga J , Ishibashi S , Oka T , Yagyu H , Tozawa R , Fujimoto A , Shionoiri F , Yahagi N , Kraemer FB , Tsutsumi O , Yamada N |
| Ref : Proc Natl Acad Sci U S A , 97 :787 , 2000 |
| Abstract : Osuga_2000_Proc.Natl.Acad.Sci.U.S.A_97_787 |
| ESTHER : Osuga_2000_Proc.Natl.Acad.Sci.U.S.A_97_787 |
| PubMedSearch : Osuga_2000_Proc.Natl.Acad.Sci.U.S.A_97_787 |
| PubMedID: 10639158 |
| Gene_locus related to this paper: human-LIPE , mouse-hslip |