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| Title : Intrinsically low open probability of alpha7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological temperatures - Williams_2012_Mol.Pharmacol_82_746 |
| Author(s) : Williams DK , Peng C , Kimbrell MR , Papke RL |
| Ref : Molecular Pharmacology , 82 :746 , 2012 |
| Abstract : Williams_2012_Mol.Pharmacol_82_746 |
| ESTHER : Williams_2012_Mol.Pharmacol_82_746 |
| PubMedSearch : Williams_2012_Mol.Pharmacol_82_746 |
| PubMedID: 22828799 |
| Title : Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations - Williams_2011_Biochem.Pharmacol_82(8)_915 |
| Author(s) : Williams DK , Wang J , Papke RL |
| Ref : Biochemical Pharmacology , 82 :915 , 2011 |
| Abstract : Williams_2011_Biochem.Pharmacol_82(8)_915 |
| ESTHER : Williams_2011_Biochem.Pharmacol_82(8)_915 |
| PubMedSearch : Williams_2011_Biochem.Pharmacol_82(8)_915 |
| PubMedID: 21575610 |
| Title : Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper - Papke_2011_Neuropharmacol_60_159 |
| Author(s) : Papke RL , Stokes C , Williams DK , Wang J , Horenstein NA |
| Ref : Neuropharmacology , 60 :159 , 2011 |
| Abstract : Papke_2011_Neuropharmacol_60_159 |
| ESTHER : Papke_2011_Neuropharmacol_60_159 |
| PubMedSearch : Papke_2011_Neuropharmacol_60_159 |
| PubMedID: 20650284 |
| Title : The effective opening of nicotinic acetylcholine receptors with single agonist binding sites - Williams_2011_J.Gen.Physiol_137_369 |
| Author(s) : Williams DK , Stokes C , Horenstein NA , Papke RL |
| Ref : Journal of General Physiology , 137 :369 , 2011 |
| Abstract : Williams_2011_J.Gen.Physiol_137_369 |
| ESTHER : Williams_2011_J.Gen.Physiol_137_369 |
| PubMedSearch : Williams_2011_J.Gen.Physiol_137_369 |
| PubMedID: 21444659 |
| Title : Investigation of the molecular mechanism of the alpha7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states - Williams_2011_Mol.Pharmacol_80_1013 |
| Author(s) : Williams DK , Wang J , Papke RL |
| Ref : Molecular Pharmacology , 80 :1013 , 2011 |
| Abstract : Williams_2011_Mol.Pharmacol_80_1013 |
| ESTHER : Williams_2011_Mol.Pharmacol_80_1013 |
| PubMedSearch : Williams_2011_Mol.Pharmacol_80_1013 |
| PubMedID: 21885620 |
| Title : Poster: Positive and negative cooperativity of agonist and allosteric modulator binding in alpha7 nAChR: Looking for the therapeutic window - |
| Author(s) : Papke RL , Williams DK , Wang J , Horenstein NA |
| Ref : Biochemical Pharmacology , 82 :1031 , 2011 |
| PubMedID: |