Full name : Wille Timo
First name : Timo
Mail : Bundeswehr Institute of Pharmacology and Toxicology, Munich
Zip Code :
City :
Country : Germany
Email : TimoWille@bundeswehr.org
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Fax :
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Directory :
| Title : AChE reactivation in Precision-cut lung slices following organophosphorus compound poisoning - Golitz_2023_Toxicol.Lett__ |
| Author(s) : Golitz F , Herbert J , Worek F , Wille T |
| Ref : Toxicol Lett , : , 2023 |
| Abstract : Golitz_2023_Toxicol.Lett__ |
| ESTHER : Golitz_2023_Toxicol.Lett__ |
| PubMedSearch : Golitz_2023_Toxicol.Lett__ |
| PubMedID: 38160862 |
| Title : The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents - Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| Author(s) : Keuler T , Lemke C , Elsinghorst PW , Iriepa I , Chioua M , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Wille T , Bartz U , Deuther-Conrad W , Marco-Contelles J , Gutschow M |
| Ref : ACS Pharmacol Transl Sci , 5 :1097 , 2022 |
| Abstract : Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| ESTHER : Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| PubMedSearch : Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| PubMedID: 36407962 |
| Title : Aminoalkoxy-substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase - Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| Author(s) : Elsinghorst PW , Wille T , Baric D , Mertens MD , Baumann M , Kuppers J , Gutschow M |
| Ref : Arch Pharm (Weinheim) , :e2200208 , 2022 |
| Abstract : Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| ESTHER : Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| PubMedSearch : Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| PubMedID: 35876340 |
| Title : Human HepaRG liver spheroids: cold storage protocol and study on pyridinium oxime-induced hepatotoxicity in vitro - Horn_2022_Chem.Biol.Interact__110285 |
| Author(s) : Horn G , Kranawetvogl T , John H , Weigel C , Rauen U , Worek F , Wille T |
| Ref : Chemico-Biological Interactions , :110285 , 2022 |
| Abstract : Horn_2022_Chem.Biol.Interact__110285 |
| ESTHER : Horn_2022_Chem.Biol.Interact__110285 |
| PubMedSearch : Horn_2022_Chem.Biol.Interact__110285 |
| PubMedID: 36442613 |
| Title : Release of protein-bound nerve agents by excess fluoride from whole blood: GC-MS\/MS method development, validation, and application to a real-life denatured blood sample - Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 |
| Author(s) : Koller M , Thiermann H , Worek F , Wille T |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1179 :122693 , 2021 |
| Abstract : Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 |
| ESTHER : Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 |
| PubMedSearch : Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 |
| PubMedID: 34171608 |
| Title : Post-VX exposure treatment of rats with engineered phosphotriesterases - Stigler_2021_Arch.Toxicol__ |
| Author(s) : Stigler L , Kohler A , Koller M , Job L , Escher B , Potschka H , Thiermann H , Skerra A , Worek F , Wille T |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : Stigler_2021_Arch.Toxicol__ |
| ESTHER : Stigler_2021_Arch.Toxicol__ |
| PubMedSearch : Stigler_2021_Arch.Toxicol__ |
| PubMedID: 34962578 |
| Title : Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense - Tigges_2021_Arch.Toxicol__ |
| Author(s) : Tigges J , Worek F , Thiermann H , Wille T |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : Tigges_2021_Arch.Toxicol__ |
| ESTHER : Tigges_2021_Arch.Toxicol__ |
| PubMedSearch : Tigges_2021_Arch.Toxicol__ |
| PubMedID: 34778934 |
| Title : Organophosphorus compounds and oximes: a critical review - Worek_2020_Arch.Toxicol_94_2275 |
| Author(s) : Worek F , Thiermann H , Wille T |
| Ref : Archives of Toxicology , 94 :2275 , 2020 |
| Abstract : Worek_2020_Arch.Toxicol_94_2275 |
| ESTHER : Worek_2020_Arch.Toxicol_94_2275 |
| PubMedSearch : Worek_2020_Arch.Toxicol_94_2275 |
| PubMedID: 32506210 |
| Title : A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making - Amend_2020_Arch.Toxicol__ |
| Author(s) : Amend N , Langgartner J , Siegert M , Kranawetvogl T , Koller M , John H , Pflugler C , Mogele-Schmid C , Worek F , Thiermann H , Wille T |
| Ref : Archives of Toxicology , : , 2020 |
| Abstract : Amend_2020_Arch.Toxicol__ |
| ESTHER : Amend_2020_Arch.Toxicol__ |
| PubMedSearch : Amend_2020_Arch.Toxicol__ |
| PubMedID: 32303803 |
| Title : In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase - Worek_2020_Molecules_25_ |
| Author(s) : Worek F , Thiermann H , Koller M , Wille T |
| Ref : Molecules , 25 : , 2020 |
| Abstract : Worek_2020_Molecules_25_ |
| ESTHER : Worek_2020_Molecules_25_ |
| PubMedSearch : Worek_2020_Molecules_25_ |
| PubMedID: 32630769 |
| Title : Diagnostics and treatment of nerve agent poisoning-current status and future developments - Amend_2020_Ann.N.Y.Acad.Sci__ |
| Author(s) : Amend N , Niessen KV , Seeger T , Wille T , Worek F , Thiermann H |
| Ref : Annals of the New York Academy of Sciences , : , 2020 |
| Abstract : Amend_2020_Ann.N.Y.Acad.Sci__ |
| ESTHER : Amend_2020_Ann.N.Y.Acad.Sci__ |
| PubMedSearch : Amend_2020_Ann.N.Y.Acad.Sci__ |
| PubMedID: 32198755 |
| Title : Early diagnosis of nerve agent exposure with a mobile test kit and implications for medical countermeasures: a trigger to react - Wille_2020_BMJ.Mil.Health__ |
| Author(s) : Wille T , Djordjevic S , Worek F , Thiermann H , Vucinic S |
| Ref : BMJ Mil Health , : , 2020 |
| Abstract : Wille_2020_BMJ.Mil.Health__ |
| ESTHER : Wille_2020_BMJ.Mil.Health__ |
| PubMedSearch : Wille_2020_BMJ.Mil.Health__ |
| PubMedID: 32086265 |
| Title : COPD and asthma therapeutics for supportive treatment in organophosphate poisoning - Herbert_2019_Clin.Toxicol.(Phila)__1 |
| Author(s) : Herbert J , Thiermann H , Worek F , Wille T |
| Ref : Clinical Toxicology (Phila) , :1 , 2019 |
| Abstract : Herbert_2019_Clin.Toxicol.(Phila)__1 |
| ESTHER : Herbert_2019_Clin.Toxicol.(Phila)__1 |
| PubMedSearch : Herbert_2019_Clin.Toxicol.(Phila)__1 |
| PubMedID: 30696282 |
| Title : Chromenones as Multineurotargeting Inhibitors of Human Enzymes - Lemke_2019_ACS.Omega_4_22161 |
| Author(s) : Lemke C , Christmann J , Yin J , Alonso JM , Serrano E , Chioua M , Ismaili L , Martinez-Grau MA , Beadle CD , Vetman T , Dato FM , Bartz U , Elsinghorst PW , Pietsch M , Muller CE , Iriepa I , Wille T , Marco-Contelles J , Gutschow M |
| Ref : ACS Omega , 4 :22161 , 2019 |
| Abstract : Lemke_2019_ACS.Omega_4_22161 |
| ESTHER : Lemke_2019_ACS.Omega_4_22161 |
| PubMedSearch : Lemke_2019_ACS.Omega_4_22161 |
| PubMedID: 31891098 |
| Title : The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM) - Amend_2019_Toxicol.Lett_308_1 |
| Author(s) : Amend N , Thiermann H , Worek F , Wille T |
| Ref : Toxicol Lett , 308 :1 , 2019 |
| Abstract : Amend_2019_Toxicol.Lett_308_1 |
| ESTHER : Amend_2019_Toxicol.Lett_308_1 |
| PubMedSearch : Amend_2019_Toxicol.Lett_308_1 |
| PubMedID: 30858091 |
| Title : Human small bowel as model for poisoning with organophosphorus compounds - Marquart_2019_Toxicol.In.Vitro_57_76 |
| Author(s) : Marquart K , Prokopchuk O , Wilhelm D , Worek F , Thiermann H , Martignoni ME , Wille T |
| Ref : Toxicol In Vitro , 57 :76 , 2019 |
| Abstract : Marquart_2019_Toxicol.In.Vitro_57_76 |
| ESTHER : Marquart_2019_Toxicol.In.Vitro_57_76 |
| PubMedSearch : Marquart_2019_Toxicol.In.Vitro_57_76 |
| PubMedID: 30763608 |
| Title : Effect of cholinergic crisis on the potency of different emergency anaesthesia protocols in soman-poisoned rats - Marquart_2018_Clin.Toxicol.(Phila)__1 |
| Author(s) : Marquart K , Herbert J , Amend N , Thiermann H , Worek F , Wille T |
| Ref : Clinical Toxicology (Phila) , :1 , 2018 |
| Abstract : Marquart_2018_Clin.Toxicol.(Phila)__1 |
| ESTHER : Marquart_2018_Clin.Toxicol.(Phila)__1 |
| PubMedSearch : Marquart_2018_Clin.Toxicol.(Phila)__1 |
| PubMedID: 30307341 |
| Title : Human small bowel as a useful tool to investigate smooth muscle effects of potential therapeutics in organophosphate poisoning - Marquart_2018_Toxicol.Lett_293_235 |
| Author(s) : Marquart K , Prokopchuk O , Worek F , Thiermann H , Martignoni ME , Wille T |
| Ref : Toxicol Lett , 293 :235 , 2018 |
| Abstract : Marquart_2018_Toxicol.Lett_293_235 |
| ESTHER : Marquart_2018_Toxicol.Lett_293_235 |
| PubMedSearch : Marquart_2018_Toxicol.Lett_293_235 |
| PubMedID: 29154801 |
| Title : The oximes HI-6 and MMB-4 fail to reactivate soman-inhibited human and guinea pig AChE: A kinetic in vitro study - Worek_2018_Toxicol.Lett_293_216 |
| Author(s) : Worek F , Thiermann H , Wille T |
| Ref : Toxicol Lett , 293 :216 , 2018 |
| Abstract : Worek_2018_Toxicol.Lett_293_216 |
| ESTHER : Worek_2018_Toxicol.Lett_293_216 |
| PubMedSearch : Worek_2018_Toxicol.Lett_293_216 |
| PubMedID: 28993240 |
| Title : Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6 - Wille_2017_Arch.Toxicol_91_1309 |
| Author(s) : Wille T , von der Wellen J , Thiermann H , Worek F |
| Ref : Archives of Toxicology , 91 :1309 , 2017 |
| Abstract : Wille_2017_Arch.Toxicol_91_1309 |
| ESTHER : Wille_2017_Arch.Toxicol_91_1309 |
| PubMedSearch : Wille_2017_Arch.Toxicol_91_1309 |
| PubMedID: 27358236 |
| Title : Application of the Ugi Multicomponent Reaction in the Synthesis of Reactivators of Nerve Agent Inhibited Acetylcholinesterase - de Koning_2017_J.Med.Chem_60_9376 |
| Author(s) : De Koning MC , Joosen MJ , Worek F , Nachon F , van Grol M , Klaassen SD , Alkema DPW , Wille T , de Bruijn HM |
| Ref : Journal of Medicinal Chemistry , 60 :9376 , 2017 |
| Abstract : de Koning_2017_J.Med.Chem_60_9376 |
| ESTHER : de Koning_2017_J.Med.Chem_60_9376 |
| PubMedSearch : de Koning_2017_J.Med.Chem_60_9376 |
| PubMedID: 29091431 |
| Title : Catalytic bioscavengers in nerve agent poisoning: A promising approach? - Worek_2016_Toxicol.Lett_244_143 |
| Author(s) : Worek F , Thiermann H , Wille T |
| Ref : Toxicol Lett , 244 :143 , 2016 |
| Abstract : Worek_2016_Toxicol.Lett_244_143 |
| ESTHER : Worek_2016_Toxicol.Lett_244_143 |
| PubMedSearch : Worek_2016_Toxicol.Lett_244_143 |
| PubMedID: 26200600 |
| Title : Blaptica dubia as sentinels for exposure to chemical warfare agents - a pilot study - Worek_2016_Toxicol.Lett_262_12 |
| Author(s) : Worek F , Seeger T , Neumaier K , Wille T , Thiermann H |
| Ref : Toxicol Lett , 262 :12 , 2016 |
| Abstract : Worek_2016_Toxicol.Lett_262_12 |
| ESTHER : Worek_2016_Toxicol.Lett_262_12 |
| PubMedSearch : Worek_2016_Toxicol.Lett_262_12 |
| PubMedID: 27639501 |
| Title : Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection - Wille_2016_Toxicol.Lett_258_198 |
| Author(s) : Wille T , Neumaier K , Koller M , Ehinger C , Aggarwal N , Ashani Y , Goldsmith M , Sussman JL , Tawfik DS , Thiermann H , Worek F |
| Ref : Toxicol Lett , 258 :198 , 2016 |
| Abstract : Wille_2016_Toxicol.Lett_258_198 |
| ESTHER : Wille_2016_Toxicol.Lett_258_198 |
| PubMedSearch : Wille_2016_Toxicol.Lett_258_198 |
| PubMedID: 27397758 |
| Title : Kinetics of pesticide degradation by human fresh frozen plasma (FFP) in vitro - von der Wellen_2016_Toxicol.Lett_244_124 |
| Author(s) : von der Wellen J , Bierwisch A , Worek F , Thiermann H , Wille T |
| Ref : Toxicol Lett , 244 :124 , 2016 |
| Abstract : von der Wellen_2016_Toxicol.Lett_244_124 |
| ESTHER : von der Wellen_2016_Toxicol.Lett_244_124 |
| PubMedSearch : von der Wellen_2016_Toxicol.Lett_244_124 |
| PubMedID: 26220518 |
| Title : Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase - Winter_2016_Toxicol.Lett_244_136 |
| Author(s) : Winter M , Wille T , Musilek K , Kuca K , Thiermann H , Worek F |
| Ref : Toxicol Lett , 244 :136 , 2016 |
| Abstract : Winter_2016_Toxicol.Lett_244_136 |
| ESTHER : Winter_2016_Toxicol.Lett_244_136 |
| PubMedSearch : Winter_2016_Toxicol.Lett_244_136 |
| PubMedID: 26210933 |
| Title : Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics - Worek_2016_Toxicology_350-352_25 |
| Author(s) : Worek F , Koller M , Thiermann H , Wille T |
| Ref : Toxicology , 350-352 :25 , 2016 |
| Abstract : Worek_2016_Toxicology_350-352_25 |
| ESTHER : Worek_2016_Toxicology_350-352_25 |
| PubMedSearch : Worek_2016_Toxicology_350-352_25 |
| PubMedID: 27153754 |
| Title : A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity - Mertens_2016_Toxicol.Lett_244_161 |
| Author(s) : Mertens MD , Bierwisch A , Li T , Gutschow M , Thiermann H , Wille T , Elsinghorst PW |
| Ref : Toxicol Lett , 244 :161 , 2016 |
| Abstract : Mertens_2016_Toxicol.Lett_244_161 |
| ESTHER : Mertens_2016_Toxicol.Lett_244_161 |
| PubMedSearch : Mertens_2016_Toxicol.Lett_244_161 |
| PubMedID: 26494253 |
| Title : On-site analysis of acetylcholinesterase and butyrylcholinesterase activity with the ChE check mobile test kit-Determination of reference values and their relevance for diagnosis of exposure to organophosphorus compounds - Worek_2016_Toxicol.Lett_249_22 |
| Author(s) : Worek F , Schilha M , Neumaier K , Aurbek N , Wille T , Thiermann H , Kehe K |
| Ref : Toxicol Lett , 249 :22 , 2016 |
| Abstract : Worek_2016_Toxicol.Lett_249_22 |
| ESTHER : Worek_2016_Toxicol.Lett_249_22 |
| PubMedSearch : Worek_2016_Toxicol.Lett_249_22 |
| PubMedID: 27033775 |
| Title : Kinetic analysis of interactions of amodiaquine with human cholinesterases and organophosphorus compounds - Bierwisch_2016_Toxicol.Lett_246_49 |
| Author(s) : Bierwisch A , Wille T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 246 :49 , 2016 |
| Abstract : Bierwisch_2016_Toxicol.Lett_246_49 |
| ESTHER : Bierwisch_2016_Toxicol.Lett_246_49 |
| PubMedSearch : Bierwisch_2016_Toxicol.Lett_246_49 |
| PubMedID: 26851641 |
| Title : Oximes in organophosphate poisoning: 60 years of hope and despair - Worek_2016_Chem.Biol.Interact_259_93 |
| Author(s) : Worek F , Thiermann H , Wille T |
| Ref : Chemico-Biological Interactions , 259 :93 , 2016 |
| Abstract : Worek_2016_Chem.Biol.Interact_259_93 |
| ESTHER : Worek_2016_Chem.Biol.Interact_259_93 |
| PubMedSearch : Worek_2016_Chem.Biol.Interact_259_93 |
| PubMedID: 27125761 |
| Title : Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase - Horn_2015_Arch.Toxicol_89_405 |
| Author(s) : Horn G , Wille T , Musilek K , Kuca K , Thiermann H , Worek F |
| Ref : Archives of Toxicology , 89 :405 , 2015 |
| Abstract : Horn_2015_Arch.Toxicol_89_405 |
| ESTHER : Horn_2015_Arch.Toxicol_89_405 |
| PubMedSearch : Horn_2015_Arch.Toxicol_89_405 |
| PubMedID: 24912784 |
| Title : Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes - Worek_2015_Toxicol.In.Vitro_30_514 |
| Author(s) : Worek F , Herkert NM , Koller M , Thiermann H , Wille T |
| Ref : Toxicol In Vitro , 30 :514 , 2015 |
| Abstract : Worek_2015_Toxicol.In.Vitro_30_514 |
| ESTHER : Worek_2015_Toxicol.In.Vitro_30_514 |
| PubMedSearch : Worek_2015_Toxicol.In.Vitro_30_514 |
| PubMedID: 26368669 |
| Title : Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro - Worek_2014_Arch.Toxicol_88_1257 |
| Author(s) : Worek F , Seeger T , Goldsmith M , Ashani Y , Leader H , Sussman JL , Tawfik DS , Thiermann H , Wille T |
| Ref : Archives of Toxicology , 88 :1257 , 2014 |
| Abstract : Worek_2014_Arch.Toxicol_88_1257 |
| ESTHER : Worek_2014_Arch.Toxicol_88_1257 |
| PubMedSearch : Worek_2014_Arch.Toxicol_88_1257 |
| PubMedID: 24477626 |
| Title : In vitro kinetics of nerve agent degradation by fresh frozen plasma (FFP) - Wille_2014_Arch.Toxicol_88_301 |
| Author(s) : Wille T , Thiermann H , Worek F |
| Ref : Archives of Toxicology , 88 :301 , 2014 |
| Abstract : Wille_2014_Arch.Toxicol_88_301 |
| ESTHER : Wille_2014_Arch.Toxicol_88_301 |
| PubMedSearch : Wille_2014_Arch.Toxicol_88_301 |
| PubMedID: 24057572 |
| Title : Effectiveness of a substituted beta-cyclodextrin to prevent cyclosarin toxicity in vivo - Worek_2014_Toxicol.Lett_226_222 |
| Author(s) : Worek F , Seeger T , Zengerle M , Kubik S , Thiermann H , Wille T |
| Ref : Toxicol Lett , 226 :222 , 2014 |
| Abstract : Worek_2014_Toxicol.Lett_226_222 |
| ESTHER : Worek_2014_Toxicol.Lett_226_222 |
| PubMedSearch : Worek_2014_Toxicol.Lett_226_222 |
| PubMedID: 24561299 |
| Title : Adaptation of a dynamic in vitro model with real-time determination of butyrylcholinesterase activity in the presence of cyclosarin and an oxime - Worek_2014_Toxicol.In.Vitro_29_162 |
| Author(s) : Worek F , Horn G , Wille T , Thiermann H |
| Ref : Toxicol In Vitro , 29 :162 , 2014 |
| Abstract : Worek_2014_Toxicol.In.Vitro_29_162 |
| ESTHER : Worek_2014_Toxicol.In.Vitro_29_162 |
| PubMedSearch : Worek_2014_Toxicol.In.Vitro_29_162 |
| PubMedID: 25450746 |
| Title : Functionalized cyclodextrins bearing an alpha nucleophile - A promising way to degrade nerve agents - Estour_2013_Chem.Biol.Interact_203_202 |
| Author(s) : Estour F , Letort S , Muller S , Kalakuntla RK , Le Provost R , Wille T , Reiter G , Worek F , Lafont O , Gouhier G |
| Ref : Chemico-Biological Interactions , 203 :202 , 2013 |
| Abstract : Estour_2013_Chem.Biol.Interact_203_202 |
| ESTHER : Estour_2013_Chem.Biol.Interact_203_202 |
| PubMedSearch : Estour_2013_Chem.Biol.Interact_203_202 |
| PubMedID: 23123247 |
| Title : Investigation of kinetic interactions between approved oximes and human acetylcholinesterase inhibited by pesticide carbamates - Wille_2013_Chem.Biol.Interact_206_569 |
| Author(s) : Wille T , Kaltenbach L , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :569 , 2013 |
| Abstract : Wille_2013_Chem.Biol.Interact_206_569 |
| ESTHER : Wille_2013_Chem.Biol.Interact_206_569 |
| PubMedSearch : Wille_2013_Chem.Biol.Interact_206_569 |
| PubMedID: 23962483 |
| Title : New modified beta-cyclodextrin derivatives as detoxifying agents of chemical warfare agents (I). Synthesis and preliminary screening: Evaluation of the detoxification using a half-quantitative enzymatic assay - Kalakuntla_2013_Toxicol.Lett_216_200 |
| Author(s) : Kalakuntla RK , Wille T , Le Provost R , Letort S , Reiter G , Muller S , Thiermann H , Worek F , Gouhier G , Lafont O , Estour F |
| Ref : Toxicol Lett , 216 :200 , 2013 |
| Abstract : Kalakuntla_2013_Toxicol.Lett_216_200 |
| ESTHER : Kalakuntla_2013_Toxicol.Lett_216_200 |
| PubMedSearch : Kalakuntla_2013_Toxicol.Lett_216_200 |
| PubMedID: 23201439 |
| Title : Fourteenth International Medical Chemical Defence Conference 2013 Translation of experimental research for improved treatment of chemical warfare agents - |
| Author(s) : Wille T , Worek F , Thiermann H |
| Ref : Chemico-Biological Interactions , 206 :433 , 2013 |
| PubMedID: 23920049 |
| Title : Structural requirements for effective oximes - Evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes - Worek_2013_Chem.Biol.Interact_203_125 |
| Author(s) : Worek F , Wille T , Koller M , Thiermann H |
| Ref : Chemico-Biological Interactions , 203 :125 , 2013 |
| Abstract : Worek_2013_Chem.Biol.Interact_203_125 |
| ESTHER : Worek_2013_Chem.Biol.Interact_203_125 |
| PubMedSearch : Worek_2013_Chem.Biol.Interact_203_125 |
| PubMedID: 22827894 |
| Title : Investigations of kinetic interactions between lipid emulsions, hydroxyethyl starch or dextran and organophosphorus compounds - Von Der Wellen_2013_Clin.Toxicol.(Phila)_51_918 |
| Author(s) : von der Wellen J , Worek F , Thiermann H , Wille T |
| Ref : Clinical Toxicology (Phila) , 51 :918 , 2013 |
| Abstract : Von Der Wellen_2013_Clin.Toxicol.(Phila)_51_918 |
| ESTHER : Von Der Wellen_2013_Clin.Toxicol.(Phila)_51_918 |
| PubMedSearch : Von Der Wellen_2013_Clin.Toxicol.(Phila)_51_918 |
| PubMedID: 24199642 |
| Title : Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships - Worek_2012_Biochem.Pharmacol_83_1700 |
| Author(s) : Worek F , Wille T , Koller M , Thiermann H |
| Ref : Biochemical Pharmacology , 83 :1700 , 2012 |
| Abstract : Worek_2012_Biochem.Pharmacol_83_1700 |
| ESTHER : Worek_2012_Biochem.Pharmacol_83_1700 |
| PubMedSearch : Worek_2012_Biochem.Pharmacol_83_1700 |
| PubMedID: 22649796 |
| Title : In vitro detoxification of cyclosarin (GF) by modified cyclodextrins - Muller_2011_Toxicol.Lett_200_53 |
| Author(s) : Muller S , Koller M , Le Provost R , Lafont O , Estour F , Wille T , Thiermann H , Worek F , Reiter G |
| Ref : Toxicol Lett , 200 :53 , 2011 |
| Abstract : Muller_2011_Toxicol.Lett_200_53 |
| ESTHER : Muller_2011_Toxicol.Lett_200_53 |
| PubMedSearch : Muller_2011_Toxicol.Lett_200_53 |
| PubMedID: 21035528 |
| Title : In vitro kinetic interactions of DEET, pyridostigmine and organophosphorus pesticides with human cholinesterases - Wille_2011_Chem.Biol.Interact_190_79 |
| Author(s) : Wille T , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 190 :79 , 2011 |
| Abstract : Wille_2011_Chem.Biol.Interact_190_79 |
| ESTHER : Wille_2011_Chem.Biol.Interact_190_79 |
| PubMedSearch : Wille_2011_Chem.Biol.Interact_190_79 |
| PubMedID: 21354413 |
| Title : In vitro kinetic interactions of DEET, pyridostigmine and organophosphorus pesticides with human cholinesterases - Response to the letter to the editor - |
| Author(s) : Wille T , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 193 :108 , 2011 |
| PubMedID: |
| Title : Pre- and post-treatment effect of physostigmine on soman-inhibited human erythrocyte and muscle acetylcholinesterase in vitro - Herkert_2011_Toxicol.Appl.Pharmacol_253_7 |
| Author(s) : Herkert NM , Schulz S , Wille T , Thiermann H , Hatz RA , Worek F |
| Ref : Toxicol Appl Pharmacol , 253 :7 , 2011 |
| Abstract : Herkert_2011_Toxicol.Appl.Pharmacol_253_7 |
| ESTHER : Herkert_2011_Toxicol.Appl.Pharmacol_253_7 |
| PubMedSearch : Herkert_2011_Toxicol.Appl.Pharmacol_253_7 |
| PubMedID: 21402092 |
| Title : Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase - Worek_2011_Toxicol.Lett_200_19 |
| Author(s) : Worek F , Aurbek N , Wille T , Eyer P , Thiermann H |
| Ref : Toxicol Lett , 200 :19 , 2011 |
| Abstract : Worek_2011_Toxicol.Lett_200_19 |
| ESTHER : Worek_2011_Toxicol.Lett_200_19 |
| PubMedSearch : Worek_2011_Toxicol.Lett_200_19 |
| PubMedID: 20971170 |
| Title : Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach - Worek_2011_J.Enzyme.Inhib.Med.Chem_26_303 |
| Author(s) : Worek F , Aurbek N , Wille T , Eyer P , Thiermann H |
| Ref : J Enzyme Inhib Med Chem , 26 :303 , 2011 |
| Abstract : Worek_2011_J.Enzyme.Inhib.Med.Chem_26_303 |
| ESTHER : Worek_2011_J.Enzyme.Inhib.Med.Chem_26_303 |
| PubMedSearch : Worek_2011_J.Enzyme.Inhib.Med.Chem_26_303 |
| PubMedID: 20807085 |
| Title : Optimized strategies to synthesize beta-cyclodextrin-oxime conjugates as a new generation of organophosphate scavengers - Le Provost_2011_Org.Biomol.Chem_9_3026 |
| Author(s) : Le Provost R , Wille T , Louise L , Masurier N , Muller S , Reiter G , Renard PY , Lafont O , Worek F , Estour F |
| Ref : Org Biomol Chem , 9 :3026 , 2011 |
| Abstract : Le Provost_2011_Org.Biomol.Chem_9_3026 |
| ESTHER : Le Provost_2011_Org.Biomol.Chem_9_3026 |
| PubMedSearch : Le Provost_2011_Org.Biomol.Chem_9_3026 |
| PubMedID: 21373706 |
| Title : Evaluation of 6,6'-dithionicotinic acid as alternative chromogen in a modified Ellman method--comparison in various species - Wille_2011_Toxicol.Mech.Methods_21_533 |
| Author(s) : Wille T , Thiermann H , Worek F |
| Ref : Toxicol Mech Methods , 21 :533 , 2011 |
| Abstract : Wille_2011_Toxicol.Mech.Methods_21_533 |
| ESTHER : Wille_2011_Toxicol.Mech.Methods_21_533 |
| PubMedSearch : Wille_2011_Toxicol.Mech.Methods_21_533 |
| PubMedID: 21470076 |
| Title : Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: a modified kinetic approach - Worek_2010_Toxicol.Appl.Pharmacol_249_231 |
| Author(s) : Worek F , Wille T , Aurbek N , Eyer P , Thiermann H |
| Ref : Toxicol Appl Pharmacol , 249 :231 , 2010 |
| Abstract : Worek_2010_Toxicol.Appl.Pharmacol_249_231 |
| ESTHER : Worek_2010_Toxicol.Appl.Pharmacol_249_231 |
| PubMedSearch : Worek_2010_Toxicol.Appl.Pharmacol_249_231 |
| PubMedID: 20888357 |
| Title : Development of a high-throughput screening for nerve agent detoxifying materials using a fully-automated robot-assisted biological assay - Wille_2010_Toxicol.In.Vitro_24_1026 |
| Author(s) : Wille T , Thiermann H , Worek F |
| Ref : Toxicol In Vitro , 24 :1026 , 2010 |
| Abstract : Wille_2010_Toxicol.In.Vitro_24_1026 |
| ESTHER : Wille_2010_Toxicol.In.Vitro_24_1026 |
| PubMedSearch : Wille_2010_Toxicol.In.Vitro_24_1026 |
| PubMedID: 19961920 |
| Title : Kinetic analysis of interactions between alkylene-linked bis-pyridiniumaldoximes and human acetylcholinesterases inhibited by various organophosphorus compounds - Wille_2010_Biochem.Pharmacol_80_941 |
| Author(s) : Wille T , Ekstrom F , Lee JC , Pang YP , Thiermann H , Worek F |
| Ref : Biochemical Pharmacology , 80 :941 , 2010 |
| Abstract : Wille_2010_Biochem.Pharmacol_80_941 |
| ESTHER : Wille_2010_Biochem.Pharmacol_80_941 |
| PubMedSearch : Wille_2010_Biochem.Pharmacol_80_941 |
| PubMedID: 20510679 |
| Title : Detoxification of nerve agents by a substituted beta-cyclodextrin: application of a modified biological assay - Wille_2009_Toxicology_265_96 |
| Author(s) : Wille T , Tenberken O , Reiter G , Muller S , Le Provost R , Lafont O , Estour F , Thiermann H , Worek F |
| Ref : Toxicology , 265 :96 , 2009 |
| Abstract : Wille_2009_Toxicology_265_96 |
| ESTHER : Wille_2009_Toxicology_265_96 |
| PubMedSearch : Wille_2009_Toxicology_265_96 |
| PubMedID: 19800384 |