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| Title : Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis - Ghosh_2018_J.Med.Chem_61_4561 |
| Author(s) : Ghosh AK , P RN , Kovela S , Rao KV , Brindisi M , Osswald HL , Amano M , Aoki M , Agniswamy J , Wang YF , Weber IT , Mitsuya H |
| Ref : Journal of Medicinal Chemistry , 61 :4561 , 2018 |
| Abstract : Ghosh_2018_J.Med.Chem_61_4561 |
| ESTHER : Ghosh_2018_J.Med.Chem_61_4561 |
| PubMedSearch : Ghosh_2018_J.Med.Chem_61_4561 |
| PubMedID: 29763303 |
| Title : Crystal structure of the Geobacillus stearothermophilus carboxylesterase Est55 and its activation of prodrug CPT-11 - Liu_2007_J.Mol.Biol_367_212 |
| Author(s) : Liu P , Ewis HE , Tai PC , Lu CD , Weber IT |
| Ref : Journal of Molecular Biology , 367 :212 , 2007 |
| Abstract : Liu_2007_J.Mol.Biol_367_212 |
| ESTHER : Liu_2007_J.Mol.Biol_367_212 |
| PubMedSearch : Liu_2007_J.Mol.Biol_367_212 |
| PubMedID: 17239398 |
| Gene_locus related to this paper: geost-est50 |
| Title : Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance - Ghosh_2006_J.Med.Chem_49_5252 |
| Author(s) : Ghosh AK , Sridhar PR , Leshchenko S , Hussain AK , Li J , Kovalevsky AY , Walters DE , Wedekind JE , Grum-Tokars V , Das D , Koh Y , Maeda K , Gatanaga H , Weber IT , Mitsuya H |
| Ref : Journal of Medicinal Chemistry , 49 :5252 , 2006 |
| Abstract : Ghosh_2006_J.Med.Chem_49_5252 |
| ESTHER : Ghosh_2006_J.Med.Chem_49_5252 |
| PubMedSearch : Ghosh_2006_J.Med.Chem_49_5252 |
| PubMedID: 16913714 |
| Title : Covalent reaction intermediate revealed in crystal structure of the Geobacillus stearothermophilus carboxylesterase Est30 - Liu_2004_J.Mol.Biol_342_551 |
| Author(s) : Liu P , Wang YF , Ewis HE , Abdelal AT , Lu CD , Harrison RW , Weber IT |
| Ref : Journal of Molecular Biology , 342 :551 , 2004 |
| Abstract : Liu_2004_J.Mol.Biol_342_551 |
| ESTHER : Liu_2004_J.Mol.Biol_342_551 |
| PubMedSearch : Liu_2004_J.Mol.Biol_342_551 |
| PubMedID: 15327954 |
| Gene_locus related to this paper: geost-est30 |
| Title : Crystallization and preliminary X-ray diffraction data for the carboxylesterase Est30 from Bacillus stearothermophilus - Liu_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_1472 |
| Author(s) : Liu P , Wang YF , Ewis HE , Abdelal A , Lu CD , Weber IT |
| Ref : Acta Crystallographica D Biol Crystallogr , 59 :1472 , 2003 |
| Abstract : Liu_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_1472 |
| ESTHER : Liu_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_1472 |
| PubMedSearch : Liu_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_1472 |
| PubMedID: 12876355 |
| Gene_locus related to this paper: geost-est30 |