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| Title : Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, beta-secretase, and amyloid beta aggregation as potential treatment of Alzheimer's disease - Zareba_2023_Eur.J.Med.Chem_261_115832 |
| Author(s) : Zareba P , Latka K , Mazur G , Gryzlo B , Pasieka A , Godyn J , Panek D , Skrzypczak-Wiercioch A , Hofner GC , Latacz G , Maj M , Espargaro A , Sabate R , Jozwiak K , Wanner KT , Salat K , Malawska B , Kulig K , Bajda M |
| Ref : Eur Journal of Medicinal Chemistry , 261 :115832 , 2023 |
| Abstract : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| ESTHER : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| PubMedSearch : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| PubMedID: 37837674 |
| Title : A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment - Kaiser_2022_Toxicol.Lett_373_160 |
| Author(s) : Kaiser J , Gertzen CGW , Bernauer T , Hofner G , Niessen KV , Seeger T , Paintner FF , Wanner KT , Worek F , Thiermann H , Gohlke H |
| Ref : Toxicol Lett , 373 :160 , 2022 |
| Abstract : Kaiser_2022_Toxicol.Lett_373_160 |
| ESTHER : Kaiser_2022_Toxicol.Lett_373_160 |
| PubMedSearch : Kaiser_2022_Toxicol.Lett_373_160 |
| PubMedID: 36503818 |
| Title : New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling - Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| Author(s) : Wein T , Wanner KT , Rappengluck S , Sichler S , Niessen KV , Seeger T , Worek F , Thiermann H |
| Ref : Curr Comput Aided Drug Des , 15 :104 , 2019 |
| Abstract : Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| ESTHER : Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| PubMedSearch : Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| PubMedID: 29968541 |
| Title : Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_2653 |
| Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT |
| Ref : ChemMedChem , 13 :2653 , 2018 |
| Abstract : Rappengluck_2018_ChemMedChem_13_2653 |
| ESTHER : Rappengluck_2018_ChemMedChem_13_2653 |
| PubMedSearch : Rappengluck_2018_ChemMedChem_13_2653 |
| PubMedID: 30362667 |
| Title : Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_1806 |
| Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT |
| Ref : ChemMedChem , 13 :1806 , 2018 |
| Abstract : Rappengluck_2018_ChemMedChem_13_1806 |
| ESTHER : Rappengluck_2018_ChemMedChem_13_1806 |
| PubMedSearch : Rappengluck_2018_ChemMedChem_13_1806 |
| PubMedID: 29974635 |
| Title : In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers - Niessen_2018_Toxicol.Lett_293_190 |
| Author(s) : Niessen KV , Seeger T , Rappengluck S , Wein T , Hofner G , Wanner KT , Thiermann H , Worek F |
| Ref : Toxicol Lett , 293 :190 , 2018 |
| Abstract : Niessen_2018_Toxicol.Lett_293_190 |
| ESTHER : Niessen_2018_Toxicol.Lett_293_190 |
| PubMedSearch : Niessen_2018_Toxicol.Lett_293_190 |
| PubMedID: 29024789 |
| Title : Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor - Sichler_2018_Toxicol.Lett_293_172 |
| Author(s) : Sichler S , Hofner G , Rappengluck S , Wein T , Niessen KV , Seeger T , Worek F , Thiermann H , Paintner FF , Wanner KT |
| Ref : Toxicol Lett , 293 :172 , 2018 |
| Abstract : Sichler_2018_Toxicol.Lett_293_172 |
| ESTHER : Sichler_2018_Toxicol.Lett_293_172 |
| PubMedSearch : Sichler_2018_Toxicol.Lett_293_172 |
| PubMedID: 29146291 |
| Title : Counteracting desensitization of human alpha7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning - Scheffel_2018_Toxicol.Lett_293_149 |
| Author(s) : Scheffel C , Niessen KV , Rappengluck S , Wanner KT , Thiermann H , Worek F , Seeger T |
| Ref : Toxicol Lett , 293 :149 , 2018 |
| Abstract : Scheffel_2018_Toxicol.Lett_293_149 |
| ESTHER : Scheffel_2018_Toxicol.Lett_293_149 |
| PubMedSearch : Scheffel_2018_Toxicol.Lett_293_149 |
| PubMedID: 29248576 |
| Title : Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human alpha7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis - Scheffel_2018_Toxicol.Lett_293_157 |
| Author(s) : Scheffel C , Niessen KV , Rappengluck S , Wanner KT , Thiermann H , Worek F , Seeger T |
| Ref : Toxicol Lett , 293 :157 , 2018 |
| Abstract : Scheffel_2018_Toxicol.Lett_293_157 |
| ESTHER : Scheffel_2018_Toxicol.Lett_293_157 |
| PubMedSearch : Scheffel_2018_Toxicol.Lett_293_157 |
| PubMedID: 29191791 |
| Title : Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor - Wein_2018_Toxicol.Lett_293_184 |
| Author(s) : Wein T , Hofner G , Rappengluck S , Sichler S , Niessen KV , Seeger T , Worek F , Thiermann H , Wanner KT |
| Ref : Toxicol Lett , 293 :184 , 2018 |
| Abstract : Wein_2018_Toxicol.Lett_293_184 |
| ESTHER : Wein_2018_Toxicol.Lett_293_184 |
| PubMedSearch : Wein_2018_Toxicol.Lett_293_184 |
| PubMedID: 29097222 |