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Author Report for: Vincent JP

No contact information in database for Vincent JP

    Title: Design of a potent, selective and brain penetrant inhibitor of Wnt-deactivating enzyme Notum by optimization of a crystallographic fragment hit
    Willis NJ, Mahy W, Sipthorp J, Zhao Y, Woodward HL, Atkinson BN, Bayle ED, Svensson F, Frew S and Fish PV <14 more author(s)>
    Ref: Journal of Medicinal Chemistry, 65:7212, 2022 : PubMed


    Title: Structural Analysis and Development of Notum Fragment Screening Hits
    Zhao Y, Mahy W, Willis NJ, Woodward HL, Steadman D, Bayle ED, Atkinson BN, Sipthorp J, Vecchia L and Jones EY <11 more author(s)>
    Ref: ACS Chem Neurosci, 13:2060, 2022 : PubMed


    Title: Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
    Bayle ED, Svensson F, Atkinson BN, Steadman D, Willis NJ, Woodward HL, Whiting P, Vincent JP, Fish PV
    Ref: Journal of Medicinal Chemistry, :, 2021 : PubMed


    Title: NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
    Flanagan DJ, Pentinmikko N, Luopajarvi K, Willis NJ, Gilroy K, Raven AP, McGarry L, Englund JI, Webb AT and Sansom OJ <26 more author(s)>
    Ref: Nature, :, 2021 : PubMed


    Title: Notum Deacylates Octanoylated Ghrelin
    Zhao Y, Schuhmacher LN, Roberts M, Kakugawa S, Bineva-Todd G, Howell S, O'Reilly N, Perret C, Snijders AP and Jones EY <1 more author(s)>
    Ref: Mol Metab, :101201, 2021 : PubMed


    Title: 5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit
    Mahy W, Willis NJ, Zhao Y, Woodward HL, Svensson F, Sipthorp J, Vecchia L, Ruza RR, Hillier J and Fish PV <8 more author(s)>
    Ref: Journal of Medicinal Chemistry, 63:12942, 2020 : PubMed


    Title: Notum deacylates Wnt proteins to suppress signalling activity
    Kakugawa S, Langton PF, Zebisch M, Howell SA, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N and Vincent JP <2 more author(s)>
    Ref: Nature, 519:187, 2015 : PubMed


    Title: Cholinesterases display genuine arylacylamidase activity but are totally devoid of intrinsic peptidase activities
    Checler F, Grassi J, Vincent JP
    Ref: Journal of Neurochemistry, 62:756, 1994 : PubMed


    Title: Monoclonal antibodies allow precipitation of esterasic but not peptidasic activities associated with butyrylcholinesterase
    Checler F, Grassi J, Masson P, Vincent JP
    Ref: Journal of Neurochemistry, 55:750, 1990 : PubMed


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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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