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| Title : Pralidoxime-like reactivator with increased lipophilicity - Molecular modeling and in vitro study - Kuca_2023_Chem.Biol.Interact_14ChEPon_110734 |
| Author(s) : Kuca K , Valle da Silva JA , Nepovimova E , Pham NL , Wu W , Valis M , Wu Q , Franca TCC |
| Ref : Chemico-Biological Interactions , :110734 , 2023 |
| Abstract : Kuca_2023_Chem.Biol.Interact_14ChEPon_110734 |
| ESTHER : Kuca_2023_Chem.Biol.Interact_14ChEPon_110734 |
| PubMedSearch : Kuca_2023_Chem.Biol.Interact_14ChEPon_110734 |
| PubMedID: 37788753 |
| Title : The measured CSF\/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24h after donepezil treatment in patients with Alzheimer's disease - Valis_2023_Biomed.Pharmacother_159_114223 |
| Author(s) : Valis M , Dlabkova A , Hort J , Angelucci F , Pejchal J , Kuca K , Pavelek Z , Karasova JZ , Novotny M |
| Ref : Biomed Pharmacother , 159 :114223 , 2023 |
| Abstract : Valis_2023_Biomed.Pharmacother_159_114223 |
| ESTHER : Valis_2023_Biomed.Pharmacother_159_114223 |
| PubMedSearch : Valis_2023_Biomed.Pharmacother_159_114223 |
| PubMedID: 36630846 |
| Title : The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs - Tsianou_2023_PLoS.One_18_e0286386 |
| Author(s) : Tsianou CC , Kvetina J , Radochova V , Kohoutova D , Rejchrt S , Valis M , Karasova JZ , Tacheci I , Knoblochova V , Soukup O , Bures J |
| Ref : PLoS ONE , 18 :e0286386 , 2023 |
| Abstract : Tsianou_2023_PLoS.One_18_e0286386 |
| ESTHER : Tsianou_2023_PLoS.One_18_e0286386 |
| PubMedSearch : Tsianou_2023_PLoS.One_18_e0286386 |
| PubMedID: 37262057 |
| Title : Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities - Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| Author(s) : Chrienova Z , Nepovimova E , Andrys R , Dolezal R , Janockova J , Muckova L , Fabova L , Soukup O , Oleksak P , Valis M , Korabecny J , Marco-Contelles J , Kuca K |
| Ref : J Enzyme Inhib Med Chem , 37 :2605 , 2022 |
| Abstract : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| ESTHER : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| PubMedSearch : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| PubMedID: 36131624 |
| Title : Dextran Sodium Sulphate-Induced Gastrointestinal Injury Further Aggravates the Impact of Galantamine on the Gastric Myoelectric Activity in Experimental Pigs - Bures_2021_Pharmaceuticals.(Basel)_14_ |
| Author(s) : Bures J , Tacheci I , Kvetina J , Radochova V , Kohoutova D , Valis M , Rejchrt S , Knoblochova V , Karasova JZ |
| Ref : Pharmaceuticals (Basel) , 14 : , 2021 |
| Abstract : Bures_2021_Pharmaceuticals.(Basel)_14_ |
| ESTHER : Bures_2021_Pharmaceuticals.(Basel)_14_ |
| PubMedSearch : Bures_2021_Pharmaceuticals.(Basel)_14_ |
| PubMedID: 34207410 |
| Title : Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimes drugs dealing with cholinergic, amyloid and mitochondrial systems - Nepovimova_2020_Bioorg.Chem_107_104596 |
| Author(s) : Nepovimova E , Svobodova L , Dolezal R , Hepnarova V , Junova L , Jun D , Korabecny J , Kucera T , Gazova Z , Motykova K , Kubackova J , Bednarikova Z , Janockova J , Jesus C , Cortes L , Pina J , Rostohar D , Serpa C , Soukup O , Aitken L , Hughes RE , Musilek K , Muckova L , Jost P , Chvojkova M , Vales K , Valis M , Chrienova Z , Chalupova K , Kuca K |
| Ref : Bioorg Chem , 107 :104596 , 2020 |
| Abstract : Nepovimova_2020_Bioorg.Chem_107_104596 |
| ESTHER : Nepovimova_2020_Bioorg.Chem_107_104596 |
| PubMedSearch : Nepovimova_2020_Bioorg.Chem_107_104596 |
| PubMedID: 33421953 |
| Title : Ligand-Based Virtual Screening, Molecular Docking, Molecular Dynamics, and MM-PBSA Calculations towards the Identification of Potential Novel Ricin Inhibitors - Botelho_2020_Toxins.(Basel)_12_ |
| Author(s) : Botelho FD , Dos Santos MC , Goncalves ADS , Kuca K , Valis M , LaPlante SR , Franca TCC , de Almeida J |
| Ref : Toxins (Basel) , 12 : , 2020 |
| Abstract : Botelho_2020_Toxins.(Basel)_12_ |
| ESTHER : Botelho_2020_Toxins.(Basel)_12_ |
| PubMedSearch : Botelho_2020_Toxins.(Basel)_12_ |
| PubMedID: 33256167 |
| Title : Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease - Chalupova_2019_Eur.J.Med.Chem_168_491 |
| Author(s) : Chalupova K , Korabecny J , Bartolini M , Monti B , Lamba D , Caliandro R , Pesaresi A , Brazzolotto X , Gastellier AJ , Nachon F , Pejchal J , Jarosova M , Hepnarova V , Jun D , Hrabinova M , Dolezal R , Karasova JZ , Mzik M , Kristofikova Z , Misik J , Muckova L , Jost P , Soukup O , Benkova M , Setnicka V , Habartova L , Chvojkova M , Kleteckova L , Vales K , Mezeiova E , Uliassi E , Valis M , Nepovimova E , Bolognesi ML , Kuca K |
| Ref : Eur Journal of Medicinal Chemistry , 168 :491 , 2019 |
| Abstract : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| ESTHER : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| PubMedSearch : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| PubMedID: 30851693 |
| Gene_locus related to this paper: torca-ACHE |
| Title : N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer's Disease Therapy - Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| Author(s) : Nepovimova E , Korabecny J , Hepnarova V , Jun D , Dolezal R , Muckova L , Jost P , Soukup O , Janockova J , Pham NL , Nguyen TD , Valis M , Kuca K |
| Ref : Curr Alzheimer Res , 16 :333 , 2019 |
| Abstract : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| ESTHER : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| PubMedSearch : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| PubMedID: 30873921 |
| Title : Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon - de Paula_2018_Molecules_23_ |
| Author(s) : de Paula RL , de Almeida JSFD , Cavalcante SFA , Goncalves AS , Simas ABC , Franca TCC , Valis M , Kuca K , Nepovimova E , Granjeiro JM |
| Ref : Molecules , 23 : , 2018 |
| Abstract : de Paula_2018_Molecules_23_ |
| ESTHER : de Paula_2018_Molecules_23_ |
| PubMedSearch : de Paula_2018_Molecules_23_ |
| PubMedID: 30424582 |
| Title : A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase - Kuca_2018_BMC.Pharmacol.Toxicol_19_8 |
| Author(s) : Kuca K , Musilek K , Jun D , Karasova JZ , Nepovimova E , Soukup O , Hrabinova M , Mikler J , Franca TCC , da Cunha EFF , de Castro AA , Valis M , Ramalho TC |
| Ref : BMC Pharmacol Toxicol , 19 :8 , 2018 |
| Abstract : Kuca_2018_BMC.Pharmacol.Toxicol_19_8 |
| ESTHER : Kuca_2018_BMC.Pharmacol.Toxicol_19_8 |
| PubMedSearch : Kuca_2018_BMC.Pharmacol.Toxicol_19_8 |
| PubMedID: 29467029 |
| Title : Treatment of behavioral and psychological symptoms of dementias with psychopharmaceuticals: a review - Masopust_2018_Neuropsychiatr.Dis.Treat_14_1211 |
| Author(s) : Masopust J , Protopopova D , Valis M , Pavelek Z , Klimova B |
| Ref : Neuropsychiatr Dis Treat , 14 :1211 , 2018 |
| Abstract : Masopust_2018_Neuropsychiatr.Dis.Treat_14_1211 |
| ESTHER : Masopust_2018_Neuropsychiatr.Dis.Treat_14_1211 |
| PubMedSearch : Masopust_2018_Neuropsychiatr.Dis.Treat_14_1211 |
| PubMedID: 29785112 |
| Title : Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings - Kuca_2018_Drug.Des.Devel.Ther_12_505 |
| Author(s) : Kuca K , Karasova JZ , Soukup O , Kassa J , Novotna E , Sepsova V , Horova A , Pejchal J , Hrabinova M , Vodakova E , Jun D , Nepovimova E , Valis M , Musilek K |
| Ref : Drug Des Devel Ther , 12 :505 , 2018 |
| Abstract : Kuca_2018_Drug.Des.Devel.Ther_12_505 |
| ESTHER : Kuca_2018_Drug.Des.Devel.Ther_12_505 |
| PubMedSearch : Kuca_2018_Drug.Des.Devel.Ther_12_505 |
| PubMedID: 29563775 |
| Title : Effect of donepezil in Alzheimer disease can be measured by a computerized human analog of the Morris water maze - Hort_2014_Neurodegener.Dis_13_192 |
| Author(s) : Hort J , Andel R , Mokrisova I , Gazova I , Amlerova J , Valis M , Coulson EJ , Harrison J , Windisch M , Laczo J |
| Ref : Neurodegener Dis , 13 :192 , 2014 |
| Abstract : Hort_2014_Neurodegener.Dis_13_192 |
| ESTHER : Hort_2014_Neurodegener.Dis_13_192 |
| PubMedSearch : Hort_2014_Neurodegener.Dis_13_192 |
| PubMedID: 24192578 |