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| Title : Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships - Amend_2024_Toxicology__153741 |
| Author(s) : Amend N , Timperley CM , Bird M , Green AC , Worek F , Seeger T |
| Ref : Toxicology , :153741 , 2024 |
| Abstract : Amend_2024_Toxicology__153741 |
| ESTHER : Amend_2024_Toxicology__153741 |
| PubMedSearch : Amend_2024_Toxicology__153741 |
| PubMedID: 38311098 |
| Title : The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives - Voros_2024_Chem.Biol.Interact__110973 |
| Author(s) : Voros C , Dias J , Timperley CM , Nachon F , Brown RCD , Baati R |
| Ref : Chemico-Biological Interactions , :110973 , 2024 |
| Abstract : Voros_2024_Chem.Biol.Interact__110973 |
| ESTHER : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedSearch : Voros_2024_Chem.Biol.Interact__110973 |
| PubMedID: 38574837 |
| Title : Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice - Kassa_2022_Toxics_10_ |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxics , 10 : , 2022 |
| Abstract : Kassa_2022_Toxics_10_ |
| ESTHER : Kassa_2022_Toxics_10_ |
| PubMedSearch : Kassa_2022_Toxics_10_ |
| PubMedID: 35448453 |
| Title : Reply to Comment on Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - Timperley_2021_J.Chem.Educ_98_1468 |
| Author(s) : Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 98 :1468 , 2021 |
| Abstract : Timperley_2021_J.Chem.Educ_98_1468 |
| ESTHER : Timperley_2021_J.Chem.Educ_98_1468 |
| PubMedSearch : Timperley_2021_J.Chem.Educ_98_1468 |
| PubMedID: |
| Title : Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR - Epstein_2021_Toxicol.Lett__ |
| Author(s) : Epstein M , Bali K , Piggot TJ , Green AC , Timperley CM , Bird M , Tattersall JEH , Bermudez I , Biggin PC |
| Ref : Toxicol Lett , : , 2021 |
| Abstract : Epstein_2021_Toxicol.Lett__ |
| ESTHER : Epstein_2021_Toxicol.Lett__ |
| PubMedSearch : Epstein_2021_Toxicol.Lett__ |
| PubMedID: 33482275 |
| Title : Nomenclature, Chemical Abstracts Service Numbers, Isomer Enumeration, Ring Strain, and Stereochemistry: What Does Any of This Have to Do with an International Chemical Disarmament and Nonproliferation Treaty? - |
| Author(s) : Pontes , Schneider J , Brud P , Benderitter L , Fourie B , Tang C , Timperley CM , Forman JE |
| Ref : Journal of Chemical Education , 97 :1715 , 2020 |
| PubMedID: |
| Title : Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment - Kassa_2020_Toxicol.Mech.Methods_30_703 |
| Author(s) : Kassa J , Timperley CM , Bird M , Green AC , Tattersall JEH |
| Ref : Toxicol Mech Methods , 30 :703 , 2020 |
| Abstract : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| ESTHER : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| PubMedSearch : Kassa_2020_Toxicol.Mech.Methods_30_703 |
| PubMedID: 32878547 |
| Title : Assessment of false transmitters as treatments for nerve agent poisoning - Whitmore_2020_Toxicol.Lett_321_21 |
| Author(s) : Whitmore C , Lindsay CD , Bird M , Gore SJ , Rice H , Williams RL , Timperley CM , Green AC |
| Ref : Toxicol Lett , 321 :21 , 2020 |
| Abstract : Whitmore_2020_Toxicol.Lett_321_21 |
| ESTHER : Whitmore_2020_Toxicol.Lett_321_21 |
| PubMedSearch : Whitmore_2020_Toxicol.Lett_321_21 |
| PubMedID: 31830555 |
| Title : Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig - Price_2016_Toxicol.Lett_244_154 |
| Author(s) : Price ME , Docx CJ , Rice H , Fairhall SJ , Poole SJ , Bird M , Whiley L , Flint DP , Green AC , Timperley CM , Tattersall JE |
| Ref : Toxicol Lett , 244 :154 , 2016 |
| Abstract : Price_2016_Toxicol.Lett_244_154 |
| ESTHER : Price_2016_Toxicol.Lett_244_154 |
| PubMedSearch : Price_2016_Toxicol.Lett_244_154 |
| PubMedID: 26325216 |
| Title : Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice - Kassa_2016_Toxicol.Mech.Methods_26_334 |
| Author(s) : Kassa J , Pohanka M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Mech Methods , 26 :334 , 2016 |
| Abstract : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| ESTHER : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| PubMedSearch : Kassa_2016_Toxicol.Mech.Methods_26_334 |
| PubMedID: 27097774 |
| Title : Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines - Ring_2015_PLoS.One_10_e0135811 |
| Author(s) : Ring A , Strom BO , Turner SR , Timperley CM , Bird M , Green AC , Chad JE , Worek F , Tattersall JE |
| Ref : PLoS ONE , 10 :e0135811 , 2015 |
| Abstract : Ring_2015_PLoS.One_10_e0135811 |
| ESTHER : Ring_2015_PLoS.One_10_e0135811 |
| PubMedSearch : Ring_2015_PLoS.One_10_e0135811 |
| PubMedID: 26274808 |
| Title : Toxicity and medical countermeasure studies on the organophosphorus nerve agents VM and VX - Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| Author(s) : Rice H , Dalton CH , Price ME , Graham SJ , Green AC , Jenner J , Groombridge HJ , Timperley CM |
| Ref : Proc Math Phys Eng Sci , 471 :20140891 , 2015 |
| Abstract : Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| ESTHER : Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| PubMedSearch : Rice_2015_Proc.Math.Phys.Eng.Sci_471_20140891 |
| PubMedID: 27547080 |
| Title : Evidence of VX nerve agent use from contaminated white mustard plants - Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| Author(s) : Gravett MR , Hopkins FB , Self AJ , Webb AJ , Timperley CM , Baker MJ |
| Ref : Proc Math Phys Eng Sci , 470 :20140076 , 2014 |
| Abstract : Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| ESTHER : Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| PubMedSearch : Gravett_2014_Proc.Math.Phys.Eng.Sci_470_20140076 |
| PubMedID: 25104906 |
| Title : Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length - Niessen_2013_Chem.Biol.Interact_206_545 |
| Author(s) : Niessen KV , Seeger T , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :545 , 2013 |
| Abstract : Niessen_2013_Chem.Biol.Interact_206_545 |
| ESTHER : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedSearch : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedID: 24157926 |
| Title : Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ) - Niessen_2012_Drug.Test.Anal_4_292 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Drug Test Anal , 4 :292 , 2012 |
| Abstract : Niessen_2012_Drug.Test.Anal_4_292 |
| ESTHER : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedSearch : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedID: 22362630 |
| Title : Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro - Seeger_2012_Toxicology_294_80 |
| Author(s) : Seeger T , Eichhorn M , Lindner M , Niessen KV , Tattersall JE , Timperley CM , Bird M , Green AC , Thiermann H , Worek F |
| Ref : Toxicology , 294 :80 , 2012 |
| Abstract : Seeger_2012_Toxicology_294_80 |
| ESTHER : Seeger_2012_Toxicology_294_80 |
| PubMedSearch : Seeger_2012_Toxicology_294_80 |
| PubMedID: 22349640 |
| Title : 1,1'-(Propane-1,3-diyl)bis(4-tert-butylpyridinium) di(methanesulfonate) protects guinea pigs from soman poisoning when used as part of a combined therapy - Timperley_2012_Medchemcomm_3_352 |
| Author(s) : Timperley CM , Bird M , Green C , Price ME , Chad JE , Turner SR , Tattersall JEH |
| Ref : Medchemcomm , 3 :352 , 2012 |
| Abstract : Timperley_2012_Medchemcomm_3_352 |
| ESTHER : Timperley_2012_Medchemcomm_3_352 |
| PubMedSearch : Timperley_2012_Medchemcomm_3_352 |
| PubMedID: |
| Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891 |
| Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O |
| Ref : Chemical Research in Toxicology , 24 :1891 , 2011 |
| Abstract : Duysen_2011_Chem.Res.Toxicol_24_1891 |
| ESTHER : Duysen_2011_Chem.Res.Toxicol_24_1891 |
| PubMedSearch : Duysen_2011_Chem.Res.Toxicol_24_1891 |
| PubMedID: 21875074 |
| Gene_locus related to this paper: mouse-Ces1c |
| Title : Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist - Turner_2011_Toxicol.Lett_206_105 |
| Author(s) : Turner SR , Chad JE , Price M , Timperley CM , Bird M , Green AC , Tattersall JE |
| Ref : Toxicol Lett , 206 :105 , 2011 |
| Abstract : Turner_2011_Toxicol.Lett_206_105 |
| ESTHER : Turner_2011_Toxicol.Lett_206_105 |
| PubMedSearch : Turner_2011_Toxicol.Lett_206_105 |
| PubMedID: 21641979 |
| Title : Interaction of bispyridinium compounds with the orthosteric binding site of human alpha7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs) - Niessen_2011_Toxicol.Lett_206_100 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 206 :100 , 2011 |
| Abstract : Niessen_2011_Toxicol.Lett_206_100 |
| ESTHER : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedSearch : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedID: 21703337 |
| Title : Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase - Blum_2008_Biochemistry_47_5216 |
| Author(s) : Blum MM , Timperley CM , Williams GR , Thiermann H , Worek F |
| Ref : Biochemistry , 47 :5216 , 2008 |
| Abstract : Blum_2008_Biochemistry_47_5216 |
| ESTHER : Blum_2008_Biochemistry_47_5216 |
| PubMedSearch : Blum_2008_Biochemistry_47_5216 |
| PubMedID: 18396898 |
| Title : Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents - Briseno-Roa_2006_J.Med.Chem_49_246 |
| Author(s) : Briseno-Roa L , Hill J , Notman S , Sellers D , Smith AP , Timperley CM , Wetherell J , Williams NH , Williams GR , Fersht AR , Griffiths AD |
| Ref : Journal of Medicinal Chemistry , 49 :246 , 2006 |
| Abstract : Briseno-Roa_2006_J.Med.Chem_49_246 |
| ESTHER : Briseno-Roa_2006_J.Med.Chem_49_246 |
| PubMedSearch : Briseno-Roa_2006_J.Med.Chem_49_246 |
| PubMedID: 16392809 |
| Title : Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry - Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| Author(s) : Barr JD , Bell AJ , Bird M , Mundy JL , Murrell J , Timperley CM , Watts P , Ferrante F |
| Ref : J Am Soc Mass Spectrom , 16 :515 , 2005 |
| Abstract : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| ESTHER : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedSearch : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedID: 15792720 |