Full name : Sugimoto Hachiro
First name : Hachiro
Mail : Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501
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Country : Japan
Email : hsugimot@pharm.kyoto-u.ac.jp
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| Title : The study of ghrelin deacylation enzymes - Satou_2012_Methods.Enzymol_514_165 |
| Author(s) : Satou M , Sugimoto H |
| Ref : Methods Enzymol , 514 :165 , 2012 |
| Abstract : Satou_2012_Methods.Enzymol_514_165 |
| ESTHER : Satou_2012_Methods.Enzymol_514_165 |
| PubMedSearch : Satou_2012_Methods.Enzymol_514_165 |
| PubMedID: 22975053 |
| Title : Understanding the functional significance of ghrelin processing and degradation - Satou_2011_Peptides_32_2183 |
| Author(s) : Satou M , Nakamura Y , Ando H , Sugimoto H |
| Ref : Peptides , 32 :2183 , 2011 |
| Abstract : Satou_2011_Peptides_32_2183 |
| ESTHER : Satou_2011_Peptides_32_2183 |
| PubMedSearch : Satou_2011_Peptides_32_2183 |
| PubMedID: 21763742 |
| Title : Cadmium reduces adipocyte size and expression levels of adiponectin and Peg1\/Mest in adipose tissue - Kawakami_2010_Toxicology_267_20 |
| Author(s) : Kawakami T , Sugimoto H , Furuichi R , Kadota Y , Inoue M , Setsu K , Suzuki S , Sato M |
| Ref : Toxicology , 267 :20 , 2010 |
| Abstract : Kawakami_2010_Toxicology_267_20 |
| ESTHER : Kawakami_2010_Toxicology_267_20 |
| PubMedSearch : Kawakami_2010_Toxicology_267_20 |
| PubMedID: 19666079 |
| Title : Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors - Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| Author(s) : Takahashi J , Hijikuro I , Kihara T , Murugesh MG , Fuse S , Kunimoto R , Tsumura Y , Akaike A , Niidome T , Okuno Y , Takahashi T , Sugimoto H |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1718 , 2010 |
| Abstract : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| ESTHER : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| PubMedSearch : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| PubMedID: 20137934 |
| Title : Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors - Shen_2010_Br.J.Pharmacol_161_127 |
| Author(s) : Shen H , Kihara T , Hongo H , Wu X , Kem WR , Shimohama S , Akaike A , Niidome T , Sugimoto H |
| Ref : British Journal of Pharmacology , 161 :127 , 2010 |
| Abstract : Shen_2010_Br.J.Pharmacol_161_127 |
| ESTHER : Shen_2010_Br.J.Pharmacol_161_127 |
| PubMedSearch : Shen_2010_Br.J.Pharmacol_161_127 |
| PubMedID: 20718745 |
| Title : [Development of anti-Alzheimer's disease drug based on beta-amyloid hypothesis] - Sugimoto_2010_Yakugaku.Zasshi_130_521 |
| Author(s) : Sugimoto H |
| Ref : Yakugaku Zasshi , 130 :521 , 2010 |
| Abstract : Sugimoto_2010_Yakugaku.Zasshi_130_521 |
| ESTHER : Sugimoto_2010_Yakugaku.Zasshi_130_521 |
| PubMedSearch : Sugimoto_2010_Yakugaku.Zasshi_130_521 |
| PubMedID: 20371996 |
| Title : Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors - Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| Author(s) : Takahashi J , Hijikuro I , Kihara T , Murugesh MG , Fuse S , Tsumura Y , Akaike A , Niidome T , Takahashi T , Sugimoto H |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1721 , 2010 |
| Abstract : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| ESTHER : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| PubMedSearch : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| PubMedID: 20137941 |
| Title : Mechanisms of chronic nicotine treatment-induced enhancement of the sensitivity of cortical neurons to the neuroprotective effect of donepezil in cortical neurons - Takada-Takatori_2010_J.Pharmacol.Sci_112_265 |
| Author(s) : Takada-Takatori Y , Kume T , Izumi Y , Niidome T , Fujii T , Sugimoto H , Akaike A |
| Ref : J Pharmacol Sci , 112 :265 , 2010 |
| Abstract : Takada-Takatori_2010_J.Pharmacol.Sci_112_265 |
| ESTHER : Takada-Takatori_2010_J.Pharmacol.Sci_112_265 |
| PubMedSearch : Takada-Takatori_2010_J.Pharmacol.Sci_112_265 |
| PubMedID: 20173312 |
| Title : Roles of nicotinic receptors in acetylcholinesterase inhibitor-induced neuroprotection and nicotinic receptor up-regulation - Takada-Takatori_2009_Biol.Pharm.Bull_32_318 |
| Author(s) : Takada-Takatori Y , Kume T , Izumi Y , Ohgi Y , Niidome T , Fujii T , Sugimoto H , Akaike A |
| Ref : Biol Pharm Bull , 32 :318 , 2009 |
| Abstract : Takada-Takatori_2009_Biol.Pharm.Bull_32_318 |
| ESTHER : Takada-Takatori_2009_Biol.Pharm.Bull_32_318 |
| PubMedSearch : Takada-Takatori_2009_Biol.Pharm.Bull_32_318 |
| PubMedID: 19252271 |
| Title : Thioesterase activity and subcellular localization of acylprotein thioesterase 1\/lysophospholipase 1 - Hirano_2009_Biochim.Biophys.Acta_1791_797 |
| Author(s) : Hirano T , Kishi M , Sugimoto H , Taguchi R , Obinata H , Ohshima N , Tatei K , Izumi T |
| Ref : Biochimica & Biophysica Acta , 1791 :797 , 2009 |
| Abstract : Hirano_2009_Biochim.Biophys.Acta_1791_797 |
| ESTHER : Hirano_2009_Biochim.Biophys.Acta_1791_797 |
| PubMedSearch : Hirano_2009_Biochim.Biophys.Acta_1791_797 |
| PubMedID: 19439193 |
| Title : Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe\/PS1dE9 mouse model of Alzheimer's disease - Goto_2008_Eur.J.Pharmacol_583_84 |
| Author(s) : Goto Y , Niidome T , Hongo H , Akaike A , Kihara T , Sugimoto H |
| Ref : European Journal of Pharmacology , 583 :84 , 2008 |
| Abstract : Goto_2008_Eur.J.Pharmacol_583_84 |
| ESTHER : Goto_2008_Eur.J.Pharmacol_583_84 |
| PubMedSearch : Goto_2008_Eur.J.Pharmacol_583_84 |
| PubMedID: 18282567 |
| Title : Mechanisms of alpha7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment - Takada-Takatori_2008_Eur.J.Pharmacol_590_150 |
| Author(s) : Takada-Takatori Y , Kume T , Ohgi Y , Fujii T , Niidome T , Sugimoto H , Akaike A |
| Ref : European Journal of Pharmacology , 590 :150 , 2008 |
| Abstract : Takada-Takatori_2008_Eur.J.Pharmacol_590_150 |
| ESTHER : Takada-Takatori_2008_Eur.J.Pharmacol_590_150 |
| PubMedSearch : Takada-Takatori_2008_Eur.J.Pharmacol_590_150 |
| PubMedID: 18585378 |
| Title : Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil - Takada-Takatori_2008_J.Neurosci.Res_86_3575 |
| Author(s) : Takada-Takatori Y , Kume T , Ohgi Y , Izumi Y , Niidome T , Fujii T , Sugimoto H , Akaike A |
| Ref : Journal of Neuroscience Research , 86 :3575 , 2008 |
| Abstract : Takada-Takatori_2008_J.Neurosci.Res_86_3575 |
| ESTHER : Takada-Takatori_2008_J.Neurosci.Res_86_3575 |
| PubMedSearch : Takada-Takatori_2008_J.Neurosci.Res_86_3575 |
| PubMedID: 18655200 |
| Title : The new approach in development of anti-Alzheimer's disease drugs via the cholinergic hypothesis - Sugimoto_2008_Chem.Biol.Interact_175_204 |
| Author(s) : Sugimoto H |
| Ref : Chemico-Biological Interactions , 175 :204 , 2008 |
| Abstract : Sugimoto_2008_Chem.Biol.Interact_175_204 |
| ESTHER : Sugimoto_2008_Chem.Biol.Interact_175_204 |
| PubMedSearch : Sugimoto_2008_Chem.Biol.Interact_175_204 |
| PubMedID: 18577377 |
| Title : [New approaches for the development of anti-Alzheimer's disease drugs based on the cholinergic hypothesis and amyloid hypothesis] - |
| Author(s) : Sugimoto H |
| Ref : Nihon Yakurigaku Zasshi , 131 :338 , 2008 |
| PubMedID: 18480562 |
| Title : Donepezil potentiates nerve growth factor-induced neurite outgrowth in PC12 cells - Oda_2007_J.Pharmacol.Sci_104_349 |
| Author(s) : Oda T , Kume T , Katsuki H , Niidome T , Sugimoto H , Akaike A |
| Ref : J Pharmacol Sci , 104 :349 , 2007 |
| Abstract : Oda_2007_J.Pharmacol.Sci_104_349 |
| ESTHER : Oda_2007_J.Pharmacol.Sci_104_349 |
| PubMedSearch : Oda_2007_J.Pharmacol.Sci_104_349 |
| PubMedID: 17675796 |
| Title : Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity - Takada-Takatori_2006_Eur.J.Pharmacol_549_19 |
| Author(s) : Takada-Takatori Y , Kume T , Sugimoto M , Katsuki H , Niidome T , Sugimoto H , Fujii T , Okabe S , Akaike A |
| Ref : European Journal of Pharmacology , 549 :19 , 2006 |
| Abstract : Takada-Takatori_2006_Eur.J.Pharmacol_549_19 |
| ESTHER : Takada-Takatori_2006_Eur.J.Pharmacol_549_19 |
| PubMedSearch : Takada-Takatori_2006_Eur.J.Pharmacol_549_19 |
| PubMedID: 16996497 |
| Title : Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade - Takada-Takatori_2006_Neuropharmacol_51_474 |
| Author(s) : Takada-Takatori Y , Kume T , Sugimoto M , Katsuki H , Sugimoto H , Akaike A |
| Ref : Neuropharmacology , 51 :474 , 2006 |
| Abstract : Takada-Takatori_2006_Neuropharmacol_51_474 |
| ESTHER : Takada-Takatori_2006_Neuropharmacol_51_474 |
| PubMedSearch : Takada-Takatori_2006_Neuropharmacol_51_474 |
| PubMedID: 16762377 |
| Title : Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons - Kume_2005_Eur.J.Pharmacol_527_77 |
| Author(s) : Kume T , Sugimoto M , Takada Y , Yamaguchi T , Yonezawa A , Katsuki H , Sugimoto H , Akaike A |
| Ref : European Journal of Pharmacology , 527 :77 , 2005 |
| Abstract : Kume_2005_Eur.J.Pharmacol_527_77 |
| ESTHER : Kume_2005_Eur.J.Pharmacol_527_77 |
| PubMedSearch : Kume_2005_Eur.J.Pharmacol_527_77 |
| PubMedID: 16313899 |
| Title : [Scope and limitations of acetylcholinesterase inhibitors] - Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163 |
| Author(s) : Sugimoto H |
| Ref : Nihon Yakurigaku Zasshi , 124 :163 , 2004 |
| Abstract : Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163 |
| ESTHER : Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163 |
| PubMedSearch : Sugimoto_2004_Nihon.Yakurigaku.Zasshi_124_163 |
| PubMedID: 15333989 |
| Title : Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons - Takada_2003_J.Pharmacol.Exp.Ther_306_772 |
| Author(s) : Takada Y , Yonezawa A , Kume T , Katsuki H , Kaneko S , Sugimoto H , Akaike A |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 306 :772 , 2003 |
| Abstract : Takada_2003_J.Pharmacol.Exp.Ther_306_772 |
| ESTHER : Takada_2003_J.Pharmacol.Exp.Ther_306_772 |
| PubMedSearch : Takada_2003_J.Pharmacol.Exp.Ther_306_772 |
| PubMedID: 12734391 |
| Title : Research and development of donepezil hydrochloride, a new type of acetylcholinesterase inhibitor - Sugimoto_2002_Jpn.J.Pharmacol_89_7 |
| Author(s) : Sugimoto H , Ogura H , Arai Y , Limura Y , Yamanishi Y |
| Ref : Japanese Journal of Pharmacology , 89 :7 , 2002 |
| Abstract : Sugimoto_2002_Jpn.J.Pharmacol_89_7 |
| ESTHER : Sugimoto_2002_Jpn.J.Pharmacol_89_7 |
| PubMedSearch : Sugimoto_2002_Jpn.J.Pharmacol_89_7 |
| PubMedID: 12083745 |
| Title : Donepezil hydrochloride: a treatment drug for Alzheimer's disease - Sugimoto_2001_Chem.Rec_1_63 |
| Author(s) : Sugimoto H |
| Ref : Chem Rec , 1 :63 , 2001 |
| Abstract : Sugimoto_2001_Chem.Rec_1_63 |
| ESTHER : Sugimoto_2001_Chem.Rec_1_63 |
| PubMedSearch : Sugimoto_2001_Chem.Rec_1_63 |
| PubMedID: 11893059 |
| Title : Donepezil Hydrochloride (E2020) and Other Acetylcholinesterase Inhibitors - Sugimoto_2000_Curr.Med.Chem_7_303 |
| Author(s) : Sugimoto H , Iimura Y , Kawakami Y , Yamanishi Y |
| Ref : Curr Med Chem , 7 :303 , 2000 |
| Abstract : Sugimoto_2000_Curr.Med.Chem_7_303 |
| ESTHER : Sugimoto_2000_Curr.Med.Chem_7_303 |
| PubMedSearch : Sugimoto_2000_Curr.Med.Chem_7_303 |
| PubMedID: 10637367 |
| Title : Synthesis and biological evaluation of 1-(4-[18F]fluorobenzyl)-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine for in vivo studies of acetylcholinesterase - Lee_2000_Nucl.Med.Biol_27_741 |
| Author(s) : Lee SY , Choe YS , Sugimoto H , Kim SE , Hwang SH , Lee K , Choi Y , Lee J , Kim B |
| Ref : Nucl Med Biol , 27 :741 , 2000 |
| Abstract : Lee_2000_Nucl.Med.Biol_27_741 |
| ESTHER : Lee_2000_Nucl.Med.Biol_27_741 |
| PubMedSearch : Lee_2000_Nucl.Med.Biol_27_741 |
| PubMedID: 11150705 |
| Title : [Discovery and development of donepezil hydrochloride for the treatment of Alzheimer's disease] - Sugimoto_1999_Yakugaku.Zasshi_119_101 |
| Author(s) : Sugimoto H , Yamanishi Y , Ogura H , Iimura Y , Yamatsu K |
| Ref : Yakugaku Zasshi , 119 :101 , 1999 |
| Abstract : Sugimoto_1999_Yakugaku.Zasshi_119_101 |
| ESTHER : Sugimoto_1999_Yakugaku.Zasshi_119_101 |
| PubMedSearch : Sugimoto_1999_Yakugaku.Zasshi_119_101 |
| PubMedID: 10067428 |
| Title : The dimer and trimer of 3-hydroxybutyrate oligomer as a precursor of ketone bodies for nutritional care - Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321 |
| Author(s) : Tasaki O , Hiraide A , Shiozaki T , Yamamura H , Ninomiya N , Sugimoto H |
| Ref : JPEN J Parenter Enteral Nutr , 23 :321 , 1999 |
| Abstract : Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321 |
| ESTHER : Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321 |
| PubMedSearch : Tasaki_1999_JPEN.J.Parenter.Enteral.Nutr_23_321 |
| PubMedID: 10574479 |
| Title : Sequence, expression in Escherichia coli, and characterization of lysophospholipase II - Toyoda_1999_Biochim.Biophys.Acta_1437_182 |
| Author(s) : Toyoda T , Sugimoto H , Yamashita S |
| Ref : Biochimica & Biophysica Acta , 1437 :182 , 1999 |
| Abstract : Toyoda_1999_Biochim.Biophys.Acta_1437_182 |
| ESTHER : Toyoda_1999_Biochim.Biophys.Acta_1437_182 |
| PubMedSearch : Toyoda_1999_Biochim.Biophys.Acta_1437_182 |
| PubMedID: 10064901 |
| Gene_locus related to this paper: mouse-lypla2 |
| Title : Purification, cDNA cloning, and regulation of lysophospholipase from rat liver - Sugimoto_1996_J.Biol.Chem_271_7705 |
| Author(s) : Sugimoto H , Hayashi H , Yamashita S |
| Ref : Journal of Biological Chemistry , 271 :7705 , 1996 |
| Abstract : Sugimoto_1996_J.Biol.Chem_271_7705 |
| ESTHER : Sugimoto_1996_J.Biol.Chem_271_7705 |
| PubMedSearch : Sugimoto_1996_J.Biol.Chem_271_7705 |
| PubMedID: 8631810 |
| Gene_locus related to this paper: ratno-lypla1a |
| Title : The simulated binding of (+\/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]m eth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyses - Inoue_1996_J.Med.Chem_39_4460 |
| Author(s) : Inoue A , Kawai T , Wakita M , Iimura Y , Sugimoto H , Kawakami Y |
| Ref : Journal of Medicinal Chemistry , 39 :4460 , 1996 |
| Abstract : Inoue_1996_J.Med.Chem_39_4460 |
| ESTHER : Inoue_1996_J.Med.Chem_39_4460 |
| PubMedSearch : Inoue_1996_J.Med.Chem_39_4460 |
| PubMedID: 8893840 |
| Title : The rationale for E2020 as a potent acetylcholinesterase inhibitor - Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| Author(s) : Kawakami Y , Inoue A , Kawai T , Wakita M , Sugimoto H , Hopfinger AJ |
| Ref : Bioorganic & Medicinal Chemistry , 4 :1429 , 1996 |
| Abstract : Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| ESTHER : Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| PubMedSearch : Kawakami_1996_Bioorg.Med.Chem_4_1429 |
| PubMedID: 8894101 |
| Title : Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2- yl)methyl]piperidine hydrochloride and related compounds - Sugimoto_1995_J.Med.Chem_38_4821 |
| Author(s) : Sugimoto H , Iimura Y , Yamanishi Y , Yamatsu K |
| Ref : Journal of Medicinal Chemistry , 38 :4821 , 1995 |
| Abstract : Sugimoto_1995_J.Med.Chem_38_4821 |
| ESTHER : Sugimoto_1995_J.Med.Chem_38_4821 |
| PubMedSearch : Sugimoto_1995_J.Med.Chem_38_4821 |
| PubMedID: 7490731 |
| Title : Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-(2-phthalimidoethyl)piperidine and related derivatives - Sugimoto_1992_J.Med.Chem_35_4542 |
| Author(s) : Sugimoto H , Tsuchiya Y , Sugumi H , Higurashi K , Karibe N , Iimura Y , Sasaki A , Araki S , Yamanishi Y , Yamatsu K |
| Ref : Journal of Medicinal Chemistry , 35 :4542 , 1992 |
| Abstract : Sugimoto_1992_J.Med.Chem_35_4542 |
| ESTHER : Sugimoto_1992_J.Med.Chem_35_4542 |
| PubMedSearch : Sugimoto_1992_J.Med.Chem_35_4542 |
| PubMedID: 1469686 |
| Title : Novel piperidine derivatives. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[2-(N-benzoylamino)ethyl]piperidine derivatives - Sugimoto_1990_J.Med.Chem_33_1880 |
| Author(s) : Sugimoto H , Tsuchiya Y , Sugumi H , Higurashi K , Karibe N , Iimura Y , Sasaki A , Kawakami Y , Nakamura T , Araki S , Yamanishi Y , Yamatsu K |
| Ref : Journal of Medicinal Chemistry , 33 :1880 , 1990 |
| Abstract : Sugimoto_1990_J.Med.Chem_33_1880 |
| ESTHER : Sugimoto_1990_J.Med.Chem_33_1880 |
| PubMedSearch : Sugimoto_1990_J.Med.Chem_33_1880 |
| PubMedID: 2362265 |