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| Title : Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach - Ryan_2017_Br.J.Pharmacol_174_2209 |
| Author(s) : Ryan A , Polycarpou E , Lack NA , Evangelopoulos D , Sieg C , Halman A , Bhakta S , Eleftheriadou O , McHugh TD , Keany S , Lowe ED , Ballet R , Abuhammad A , Jacobs WR, Jr. , Ciulli A , Sim E |
| Ref : British Journal of Pharmacology , 174 :2209 , 2017 |
| Abstract : Ryan_2017_Br.J.Pharmacol_174_2209 |
| ESTHER : Ryan_2017_Br.J.Pharmacol_174_2209 |
| PubMedSearch : Ryan_2017_Br.J.Pharmacol_174_2209 |
| PubMedID: 28380256 |
| Gene_locus related to this paper: myctu-Rv3569c |
| Title : Mechanism-based inhibition of HsaD: a C-C bond hydrolase essential for survival of Mycobacterium tuberculosis in macrophage - Ryan_2014_FEMS.Microbiol.Lett_350_42 |
| Author(s) : Ryan A , Keany S , Eleftheriadou O , Ballet R , Cheng HY , Sim E |
| Ref : FEMS Microbiology Letters , 350 :42 , 2014 |
| Abstract : Ryan_2014_FEMS.Microbiol.Lett_350_42 |
| ESTHER : Ryan_2014_FEMS.Microbiol.Lett_350_42 |
| PubMedSearch : Ryan_2014_FEMS.Microbiol.Lett_350_42 |
| PubMedID: 24164668 |
| Title : Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism - Lack_2010_J.Biol.Chem_285_434 |
| Author(s) : Lack NA , Yam KC , Lowe ED , Horsman GP , Owen RL , Sim E , Eltis LD |
| Ref : Journal of Biological Chemistry , 285 :434 , 2010 |
| Abstract : Lack_2010_J.Biol.Chem_285_434 |
| ESTHER : Lack_2010_J.Biol.Chem_285_434 |
| PubMedSearch : Lack_2010_J.Biol.Chem_285_434 |
| PubMedID: 19875455 |
| Gene_locus related to this paper: myctu-Rv3569c |
| Title : Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis - Lack_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_2 |
| Author(s) : Lack N , Lowe ED , Liu J , Eltis LD , Noble ME , Sim E , Westwood IM |
| Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 64 :2 , 2008 |
| Abstract : Lack_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_2 |
| ESTHER : Lack_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_2 |
| PubMedSearch : Lack_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_2 |
| PubMedID: 18097091 |
| Gene_locus related to this paper: myctu-Rv3569c |
| Title : A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages - Van der Geize_2007_Proc.Natl.Acad.Sci.U.S.A_104_1947 |
| Author(s) : Van der Geize R , Yam K , Heuser T , Wilbrink MH , Hara H , Anderton MC , Sim E , Dijkhuizen L , Davies JE , Mohn WW , Eltis LD |
| Ref : Proc Natl Acad Sci U S A , 104 :1947 , 2007 |
| Abstract : Van der Geize_2007_Proc.Natl.Acad.Sci.U.S.A_104_1947 |
| ESTHER : Van der Geize_2007_Proc.Natl.Acad.Sci.U.S.A_104_1947 |
| PubMedSearch : Van der Geize_2007_Proc.Natl.Acad.Sci.U.S.A_104_1947 |
| PubMedID: 17264217 |
| Gene_locus related to this paper: myctu-Rv3569c |