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| Title : A novel series of [3.2.1] azabicyclic biaryl ethers as alpha3beta4 and alpha6\/4beta4 nicotinic receptor agonists - Lowe_2010_Bioorg.Med.Chem.Lett_20_4749 |
| Author(s) : Lowe JA, 3rd , DeNinno SL , Coe JW , Zhang L , Mente S , Hurst RS , Mather RJ , Ward KM , Shrikhande A , Rollema H , Johnson DE , Horner W , Gorczyca R , Tingley FD, 3rd , Kozak R , Majchrzak MJ , Tritto T , Sadlier J , Shaffer CL , Ellerbrock B , Osgood SM , MacDougall MC , McDowell LL |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :4749 , 2010 |
| Abstract : Lowe_2010_Bioorg.Med.Chem.Lett_20_4749 |
| ESTHER : Lowe_2010_Bioorg.Med.Chem.Lett_20_4749 |
| PubMedSearch : Lowe_2010_Bioorg.Med.Chem.Lett_20_4749 |
| PubMedID: 20663668 |
| Title : Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence - Rollema_2010_Br.J.Pharmacol_160_334 |
| Author(s) : Rollema H , Shrikhande A , Ward KM , Tingley FD, 3rd , Coe JW , O'Neill BT , Tseng E , Wang EQ , Mather RJ , Hurst RS , Williams KE , De Vries M , Cremers T , Bertrand S , Bertrand D |
| Ref : British Journal of Pharmacology , 160 :334 , 2010 |
| Abstract : Rollema_2010_Br.J.Pharmacol_160_334 |
| ESTHER : Rollema_2010_Br.J.Pharmacol_160_334 |
| PubMedSearch : Rollema_2010_Br.J.Pharmacol_160_334 |
| PubMedID: 20331614 |
| Title : Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates--subtype selective, high affinity alpha7 nicotinic acetylcholine receptor agonists - O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| Author(s) : O'Donnell CJ , Peng L , O'Neill BT , Arnold EP , Mather RJ , Sands SB , Shrikhande A , Lebel LA , Spracklin DK , Nedza FM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4747 , 2009 |
| Abstract : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| ESTHER : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| PubMedSearch : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| PubMedID: 19576766 |
| Title : Poster: Preclinical properties of the alpha4\/beta2 nAChR partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence - |
| Author(s) : Rollema H , Shrikhande A , Ward KM , Coe JW , Tseng E , Wang EQ , De Vries M , Cremers THIF , Bertrand S , Bertrand D |
| Ref : Biochemical Pharmacology , 78 :918 , 2009 |
| PubMedID: |
| Title : Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect - Rollema_2009_Eur.J.Pharmacol_605_114 |
| Author(s) : Rollema H , Guanowsky V , Mineur YS , Shrikhande A , Coe JW , Seymour PA , Picciotto MR |
| Ref : European Journal of Pharmacology , 605 :114 , 2009 |
| Abstract : Rollema_2009_Eur.J.Pharmacol_605_114 |
| ESTHER : Rollema_2009_Eur.J.Pharmacol_605_114 |
| PubMedSearch : Rollema_2009_Eur.J.Pharmacol_605_114 |
| PubMedID: 19168054 |
| Title : Poster: Low efficacy partial agonists of the alpha4\/beta2 nicotinic acetylcholine receptor (nAChR). Does functional efficacy govern in vivo response? - |
| Author(s) : Coe JW , Brooks PR , Wirtz MC , Vetelino MG , Arnold EP , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley Iii FD , ONeill BT , Rollema H |
| Ref : Biochemical Pharmacology , 78 :919 , 2009 |
| PubMedID: |
| Title : Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation - Coe_2005_J.Med.Chem_48_3474 |
| Author(s) : Coe JW , Brooks PR , Vetelino MG , Wirtz MC , Arnold EP , Huang J , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Heym JH , Schaeffer E , Rollema H , Lu Y , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley FD, 3rd , O'Neill BT |
| Ref : Journal of Medicinal Chemistry , 48 :3474 , 2005 |
| Abstract : Coe_2005_J.Med.Chem_48_3474 |
| ESTHER : Coe_2005_J.Med.Chem_48_3474 |
| PubMedSearch : Coe_2005_J.Med.Chem_48_3474 |
| PubMedID: 15887955 |