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Title : The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors - Graham_2012_Bioorg.Med.Chem.Lett_22_658 |
Author(s) : Graham TH , Shen HC , Liu W , Xiong Y , Verras A , Bleasby K , Bhatt UR , Chabin RM , Chen D , Chen Q , Garcia-Calvo M , Geissler WM , He H , Lassman ME , Shen Z , Tong X , Tung EC , Xie D , Xu S , Colletti SL , Tata JR , Hale JJ , Pinto S , Shen DM |
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :658 , 2012 |
Abstract : Graham_2012_Bioorg.Med.Chem.Lett_22_658 |
ESTHER : Graham_2012_Bioorg.Med.Chem.Lett_22_658 |
PubMedSearch : Graham_2012_Bioorg.Med.Chem.Lett_22_658 |
PubMedID: 22079761 |
Gene_locus related to this paper: human-PRCP |
Title : Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications - |
Author(s) : Shen HC , Hammock BD |
Ref : Journal of Medicinal Chemistry , 55 :1789 , 2012 |
PubMedID: 22168898 |
Title : Discovery of benzimidazole pyrrolidinyl amides as prolylcarboxypeptidase inhibitors - Shen_2011_Bioorg.Med.Chem.Lett_21_1299 |
Author(s) : Shen HC , Ding FX , Zhou C , Xiong Y , Verras A , Chabin RM , Xu S , Tong X , Xie D , Lassman ME , Bhatt UR , Garcia-Calvo MM , Geissler W , Shen Z , Chen D , SinhaRoy R , Hale JJ , Tata JR , Pinto S , Shen DM , Colletti SL |
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :1299 , 2011 |
Abstract : Shen_2011_Bioorg.Med.Chem.Lett_21_1299 |
ESTHER : Shen_2011_Bioorg.Med.Chem.Lett_21_1299 |
PubMedSearch : Shen_2011_Bioorg.Med.Chem.Lett_21_1299 |
PubMedID: 21315588 |
Gene_locus related to this paper: human-PRCP |
Title : Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement - Shen_2009_J.Med.Chem_52_5009 |
Author(s) : Shen HC , Ding FX , Wang S , Deng Q , Zhang X , Chen Y , Zhou G , Xu S , Chen HS , Tong X , Tong V , Mitra K , Kumar S , Tsai C , Stevenson AS , Pai LY , Alonso-Galicia M , Chen X , Soisson SM , Roy S , Zhang B , Tata JR , Berger JP , Colletti SL |
Ref : Journal of Medicinal Chemistry , 52 :5009 , 2009 |
Abstract : Shen_2009_J.Med.Chem_52_5009 |
ESTHER : Shen_2009_J.Med.Chem_52_5009 |
PubMedSearch : Shen_2009_J.Med.Chem_52_5009 |
PubMedID: 19645482 |
Title : Synthesis of dihydroxanthone derivatives and evaluation of their inhibitory activity against acetylcholinesterase: unique structural analogs of tacrine based on the BCD-ring of arisugacin - Degen_1999_Bioorg.Med.Chem.Lett_9_973 |
Author(s) : Degen SJ , Mueller KL , Shen HC , Mulder JA , Golding GM , Wei LL , Zificsak CA , Neeno-Eckwall A , Hsung RP |
Ref : Bioorganic & Medicinal Chemistry Lett , 9 :973 , 1999 |
Abstract : Degen_1999_Bioorg.Med.Chem.Lett_9_973 |
ESTHER : Degen_1999_Bioorg.Med.Chem.Lett_9_973 |
PubMedSearch : Degen_1999_Bioorg.Med.Chem.Lett_9_973 |
PubMedID: 10230623 |