Full name : Servent Denis
First name : Denis
Mail : CEA Saclay Dept d'Ingenierie et d'Etudes des Proteines - Bat 152, 91191 Gif sur Yvette
Zip Code :
City :
Country : France
Email : denis.servent@cea.fr
Phone : 33 1 69085202
Fax : 33 169089071
Website : \/\/ibitecs.cea.fr\/drf\/ibitecs\/Pages\/services\/simopro\/ltmb.aspx
Directory :
| Title : Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor - Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010 |
| Author(s) : Cieslikiewicz-Bouet M , Naldi M , Bartolini M , Perez B , Servent D , Jean L , Araoz R , Renard PY |
| Ref : Biochemical Pharmacology , :114010 , 2020 |
| Abstract : Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010 |
| ESTHER : Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010 |
| PubMedSearch : Cieslikiewicz-Bouet_2020_Biochem.Pharmacol__114010 |
| PubMedID: 32360492 |
| Title : The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions - Kessler_2017_J.Neurochem_142 Suppl 2_7 |
| Author(s) : Kessler P , Marchot P , Silva M , Servent D |
| Ref : Journal of Neurochemistry , 142 Suppl 2 :7 , 2017 |
| Abstract : Kessler_2017_J.Neurochem_142 Suppl 2_7 |
| ESTHER : Kessler_2017_J.Neurochem_142 Suppl 2_7 |
| PubMedSearch : Kessler_2017_J.Neurochem_142 Suppl 2_7 |
| PubMedID: 28326549 |
| Title : Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors - Molgo_2017_J.Neurochem_142 Suppl 2_41 |
| Author(s) : Molgo J , Marchot P , Araoz R , Benoit E , Iorga BI , Zakarian A , Taylor P , Bourne Y , Servent D |
| Ref : Journal of Neurochemistry , 142 Suppl 2 :41 , 2017 |
| Abstract : Molgo_2017_J.Neurochem_142 Suppl 2_41 |
| ESTHER : Molgo_2017_J.Neurochem_142 Suppl 2_41 |
| PubMedSearch : Molgo_2017_J.Neurochem_142 Suppl 2_41 |
| PubMedID: 28326551 |
| Title : The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases - Abd-Ella_2015_PLoS.One_10_e0126406 |
| Author(s) : Abd-Ella A , Stankiewicz M , Mikulska K , Nowak W , Pennetier C , Goulu M , Fruchart-Gaillard C , Licznar P , Apaire-Marchais V , List O , Corbel V , Servent D , Lapied B |
| Ref : PLoS ONE , 10 :e0126406 , 2015 |
| Abstract : Abd-Ella_2015_PLoS.One_10_e0126406 |
| ESTHER : Abd-Ella_2015_PLoS.One_10_e0126406 |
| PubMedSearch : Abd-Ella_2015_PLoS.One_10_e0126406 |
| PubMedID: 25961834 |
| Title : Poster: Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of alpha7 nicotinic acetylcholine receptor - |
| Author(s) : Araoz R , Bouet m , Bartolini M , Coquelle N , Colletier JP , Servent D , Molgo J , Jean L , Renard PY |
| Ref : Biochemical Pharmacology , 97 :621 , 2015 |
| PubMedID: |
| Title : Poster: Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives - |
| Author(s) : Araoz R , Hess P , Pelissier F , Benoit E , Servent D , Zakarian A , Molgo J |
| Ref : Biochemical Pharmacology , 97 :622 , 2015 |
| PubMedID: |
| Title : Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha7 from Muscle alpha1(2)betagammadelta nAChRs - Bourne_2015_Structure_23_1106 |
| Author(s) : Bourne Y , Sulzenbacher G , Radic Z , Araoz R , Reynaud M , Benoit E , Zakarian A , Servent D , Molgo J , Taylor P , Marchot P |
| Ref : Structure , 23 :1106 , 2015 |
| Abstract : Bourne_2015_Structure_23_1106 |
| ESTHER : Bourne_2015_Structure_23_1106 |
| PubMedSearch : Bourne_2015_Structure_23_1106 |
| PubMedID: 26004441 |
| Title : Neonicotinoid binding, toxicity and expression of nicotinic acetylcholine receptor subunits in the aphid Acyrthosiphon pisum - Taillebois_2014_PLoS.One_9_e96669 |
| Author(s) : Taillebois E , Beloula A , Quinchard S , Jaubert-Possamai S , Daguin A , Servent D , Tagu D , Thany SH , Tricoire-Leignel H |
| Ref : PLoS ONE , 9 :e96669 , 2014 |
| Abstract : Taillebois_2014_PLoS.One_9_e96669 |
| ESTHER : Taillebois_2014_PLoS.One_9_e96669 |
| PubMedSearch : Taillebois_2014_PLoS.One_9_e96669 |
| PubMedID: 24801634 |
| Title : Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors - Fruchart-Gaillard_2012_PLoS.One_7_e39166 |
| Author(s) : Fruchart-Gaillard C , Mourier G , Blanchet G , Vera L , Gilles N , Menez R , Marcon E , Stura EA , Servent D |
| Ref : PLoS ONE , 7 :e39166 , 2012 |
| Abstract : Fruchart-Gaillard_2012_PLoS.One_7_e39166 |
| ESTHER : Fruchart-Gaillard_2012_PLoS.One_7_e39166 |
| PubMedSearch : Fruchart-Gaillard_2012_PLoS.One_7_e39166 |
| PubMedID: 22720062 |
| Title : G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors - Maiga_2012_Toxicon_59_487 |
| Author(s) : Maiga A , Mourier G , Quinton L , Rouget C , Gales C , Denis C , Lluel P , Senard JM , Palea S , Servent D , Gilles N |
| Ref : Toxicon , 59 :487 , 2012 |
| Abstract : Maiga_2012_Toxicon_59_487 |
| ESTHER : Maiga_2012_Toxicon_59_487 |
| PubMedSearch : Maiga_2012_Toxicon_59_487 |
| PubMedID: 21419153 |
| Title : Total synthesis of pinnatoxins A and G and revision of the mode of action of pinnatoxin A - Araoz_2011_J.Am.Chem.Soc_133_10499 |
| Author(s) : Araoz R , Servent D , Molgo J , Iorga BI , Fruchart-Gaillard C , Benoit E , Gu Z , Stivala C , Zakarian A |
| Ref : Journal of the American Chemical Society , 133 :10499 , 2011 |
| Abstract : Araoz_2011_J.Am.Chem.Soc_133_10499 |
| ESTHER : Araoz_2011_J.Am.Chem.Soc_133_10499 |
| PubMedSearch : Araoz_2011_J.Am.Chem.Soc_133_10499 |
| PubMedID: 21644584 |
| Title : Muscarinic toxins - Servent_2011_Toxicon_58_455 |
| Author(s) : Servent D , Blanchet G , Mourier G , Marquer C , Marcon E , Fruchart-Gaillard C |
| Ref : Toxicon , 58 :455 , 2011 |
| Abstract : Servent_2011_Toxicon_58_455 |
| ESTHER : Servent_2011_Toxicon_58_455 |
| PubMedSearch : Servent_2011_Toxicon_58_455 |
| PubMedID: 21906611 |
| Title : Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor - Marquer_2011_J.Biol.Chem_286_31661 |
| Author(s) : Marquer C , Fruchart-Gaillard C , Letellier G , Marcon E , Mourier G , Zinn-Justin S , Menez A , Servent D , Gilquin B |
| Ref : Journal of Biological Chemistry , 286 :31661 , 2011 |
| Abstract : Marquer_2011_J.Biol.Chem_286_31661 |
| ESTHER : Marquer_2011_J.Biol.Chem_286_31661 |
| PubMedSearch : Marquer_2011_J.Biol.Chem_286_31661 |
| PubMedID: 21685390 |
| Title : Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism - Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076 |
| Author(s) : Bourne Y , Radic Z , Araoz R , Talley TT , Benoit E , Servent D , Taylor P , Molgo J , Marchot P |
| Ref : Proc Natl Acad Sci U S A , 107 :6076 , 2010 |
| Abstract : Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076 |
| ESTHER : Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076 |
| PubMedSearch : Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076 |
| PubMedID: 20224036 |
| Title : Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor - Quinton_2010_Br.J.Pharmacol_159_316 |
| Author(s) : Quinton L , Girard E , Maiga A , Rekik M , Lluel P , Masuyer G , Larregola M , Marquer C , Ciolek J , Magnin T , Wagner R , Molgo J , Thai R , Fruchart-Gaillard C , Mourier G , Chamot-Rooke J , Menez A , Palea S , Servent D , Gilles N |
| Ref : British Journal of Pharmacology , 159 :316 , 2010 |
| Abstract : Quinton_2010_Br.J.Pharmacol_159_316 |
| ESTHER : Quinton_2010_Br.J.Pharmacol_159_316 |
| PubMedSearch : Quinton_2010_Br.J.Pharmacol_159_316 |
| PubMedID: 20015090 |
| Title : Influence of MT7 toxin on the oligomerization state of the M1 muscarinic receptor - Marquer_2010_Biol.Cell_102_409 |
| Author(s) : Marquer C , Fruchart-Gaillard C , Mourier G , Grandjean O , Girard E , le Maire M , Brown S , Servent D |
| Ref : Biology of the cell , 102 :409 , 2010 |
| Abstract : Marquer_2010_Biol.Cell_102_409 |
| ESTHER : Marquer_2010_Biol.Cell_102_409 |
| PubMedSearch : Marquer_2010_Biol.Cell_102_409 |
| PubMedID: 20170475 |
| Title : Muscarinic toxins: tools for the study of the pharmacological and functional properties of muscarinic receptors - Servent_2009_J.Neurochem_109_1193 |
| Author(s) : Servent D , Fruchart-Gaillard C |
| Ref : Journal of Neurochemistry , 109 :1193 , 2009 |
| Abstract : Servent_2009_J.Neurochem_109_1193 |
| ESTHER : Servent_2009_J.Neurochem_109_1193 |
| PubMedSearch : Servent_2009_J.Neurochem_109_1193 |
| PubMedID: 19457160 |
| Title : Different interactions between MT7 toxin and the human muscarinic M1 receptor in its free and N-methylscopolamine-occupied states - Fruchart-Gaillard_2008_Mol.Pharmacol_74_1554 |
| Author(s) : Fruchart-Gaillard C , Mourier G , Marquer C , Stura E , Birdsall NJ , Servent D |
| Ref : Molecular Pharmacology , 74 :1554 , 2008 |
| Abstract : Fruchart-Gaillard_2008_Mol.Pharmacol_74_1554 |
| ESTHER : Fruchart-Gaillard_2008_Mol.Pharmacol_74_1554 |
| PubMedSearch : Fruchart-Gaillard_2008_Mol.Pharmacol_74_1554 |
| PubMedID: 18784346 |
| Title : Identification of various allosteric interaction sites on M1 muscarinic receptor using 125I-Met35-oxidized muscarinic toxin 7 - Fruchart-Gaillard_2006_Mol.Pharmacol_69_1641 |
| Author(s) : Fruchart-Gaillard C , Mourier G , Marquer C , Menez A , Servent D |
| Ref : Molecular Pharmacology , 69 :1641 , 2006 |
| Abstract : Fruchart-Gaillard_2006_Mol.Pharmacol_69_1641 |
| ESTHER : Fruchart-Gaillard_2006_Mol.Pharmacol_69_1641 |
| PubMedSearch : Fruchart-Gaillard_2006_Mol.Pharmacol_69_1641 |
| PubMedID: 16439611 |
| Title : How three-finger-fold toxins interact with various cholinergic receptors - Fruchart-Gaillard_2006_J.Mol.Neurosci_30_7 |
| Author(s) : Fruchart-Gaillard C , Mourier G , Marquer C , Menez A , Servent D |
| Ref : Journal of Molecular Neuroscience , 30 :7 , 2006 |
| Abstract : Fruchart-Gaillard_2006_J.Mol.Neurosci_30_7 |
| ESTHER : Fruchart-Gaillard_2006_J.Mol.Neurosci_30_7 |
| PubMedSearch : Fruchart-Gaillard_2006_J.Mol.Neurosci_30_7 |
| PubMedID: 17192604 |
| Title : Pharmacological and structural characterization of the interaction of snake toxins with nicotinic acetylcholine receptors. - |
| Author(s) : Servent D , Fruchart-Gaillard C , Menez A |
| Ref : Cholinergic Mechanisms, CRC Press :27 , 2004 |
| PubMedID: |
| Title : Chemical synthesis of MT1 and MT7 muscarinic toxins: critical role of Arg-34 in their interaction with M1 muscarinic receptor - Mourier_2003_Mol.Pharmacol_63_26 |
| Author(s) : Mourier G , Dutertre S , Fruchart-Gaillard C , Menez A , Servent D |
| Ref : Molecular Pharmacology , 63 :26 , 2003 |
| Abstract : Mourier_2003_Mol.Pharmacol_63_26 |
| ESTHER : Mourier_2003_Mol.Pharmacol_63_26 |
| PubMedSearch : Mourier_2003_Mol.Pharmacol_63_26 |
| PubMedID: 12488533 |
| Title : Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor - Fruchart-Gaillard_2002_Proc.Natl.Acad.Sci.U.S.A_99_3216 |
| Author(s) : Fruchart-Gaillard C , Gilquin B , Antil-Delbeke S , Le Novere N , Tamiya T , Corringer PJ , Changeux JP , Menez A , Servent D |
| Ref : Proc Natl Acad Sci U S A , 99 :3216 , 2002 |
| Abstract : Fruchart-Gaillard_2002_Proc.Natl.Acad.Sci.U.S.A_99_3216 |
| ESTHER : Fruchart-Gaillard_2002_Proc.Natl.Acad.Sci.U.S.A_99_3216 |
| PubMedSearch : Fruchart-Gaillard_2002_Proc.Natl.Acad.Sci.U.S.A_99_3216 |
| PubMedID: 11867717 |
| Title : A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken alpha7 nicotinic acetylcholine receptors - Poh_2002_Eur.J.Biochem_269_4247 |
| Author(s) : Poh SL , Mourier G , Thai R , Armugam A , Molgo J , Servent D , Jeyaseelan K , Menez A |
| Ref : European Journal of Biochemistry , 269 :4247 , 2002 |
| Abstract : Poh_2002_Eur.J.Biochem_269_4247 |
| ESTHER : Poh_2002_Eur.J.Biochem_269_4247 |
| PubMedSearch : Poh_2002_Eur.J.Biochem_269_4247 |
| PubMedID: 12199703 |
| Title : Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor - Antil-Delbeke_2000_J.Biol.Chem_275_29594 |
| Author(s) : Antil-Delbeke S , Gaillard C , Tamiya T , Corringer PJ , Changeux JP , Servent D , Menez A |
| Ref : Journal of Biological Chemistry , 275 :29594 , 2000 |
| Abstract : Antil-Delbeke_2000_J.Biol.Chem_275_29594 |
| ESTHER : Antil-Delbeke_2000_J.Biol.Chem_275_29594 |
| PubMedSearch : Antil-Delbeke_2000_J.Biol.Chem_275_29594 |
| PubMedID: 10852927 |
| Title : Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors - Servent_2000_Eur.J.Pharmacol_393_197 |
| Author(s) : Servent D , Antil-Delbeke S , Gaillard C , Corringer PJ , Changeux JP , Menez A |
| Ref : European Journal of Pharmacology , 393 :197 , 2000 |
| Abstract : Servent_2000_Eur.J.Pharmacol_393_197 |
| ESTHER : Servent_2000_Eur.J.Pharmacol_393_197 |
| PubMedSearch : Servent_2000_Eur.J.Pharmacol_393_197 |
| PubMedID: 10771013 |
| Title : Relative spatial position of a snake neurotoxin and the reduced disulfide bond alpha (Cys192-Cys193) at the alpha gamma interface of the nicotinic acetylcholine receptor - Michalet_2000_J.Biol.Chem_275_25608 |
| Author(s) : Michalet S , Teixeira F , Gilquin B , Mourier G , Servent D , Drevet P , Binder P , Tzartos SJ , Menez A , Kessler P |
| Ref : Journal of Biological Chemistry , 275 :25608 , 2000 |
| Abstract : Michalet_2000_J.Biol.Chem_275_25608 |
| ESTHER : Michalet_2000_J.Biol.Chem_275_25608 |
| PubMedSearch : Michalet_2000_J.Biol.Chem_275_25608 |
| PubMedID: 10807914 |
| Title : Chemical engineering of a three-fingered toxin with anti-alpha7 neuronal acetylcholine receptor activity - Mourier_2000_Protein.Eng_13_217 |
| Author(s) : Mourier G , Servent D , Zinn-Justin S , Menez A |
| Ref : Protein Engineering , 13 :217 , 2000 |
| Abstract : Mourier_2000_Protein.Eng_13_217 |
| ESTHER : Mourier_2000_Protein.Eng_13_217 |
| PubMedSearch : Mourier_2000_Protein.Eng_13_217 |
| PubMedID: 10775664 |
| Title : Two novel alpha-conotoxins isolated from the venom of Conus consor: isolation, synthesis and binding on the Torpedo nicotinic acetylcholine receptor - |
| Author(s) : Favreau P , Legall F , Servent D , Menez A , Molgo J , Letourneux Y |
| Ref : Journal de Physiologie (Paris) , 92 :430 , 1998 |
| PubMedID: |
| Title : How do snake curaremimetic toxins discriminate between nicotinic acetylcholine receptor subtypes - Servent_1998_Toxicol.Lett_102-103_199 |
| Author(s) : Servent D , Mourier G , Antil S , Menez A |
| Ref : Toxicol Lett , 102-103 :199 , 1998 |
| Abstract : Servent_1998_Toxicol.Lett_102-103_199 |
| ESTHER : Servent_1998_Toxicol.Lett_102-103_199 |
| PubMedSearch : Servent_1998_Toxicol.Lett_102-103_199 |
| PubMedID: 10022254 |
| Title : Artificial toxins to explore new receptors? - |
| Author(s) : Menez A , Mourier G , Kessler P , Ducancel F , Bertrand D , Corringer PJ , Changeux JP , Servent D |
| Ref : Journal de Physiologie (Paris) , 92 :468 , 1998 |
| PubMedID: |
| Title : An engineered short-chain toxin with higher affinity for the neuronalalpha7 receptor - |
| Author(s) : Servent D , Antil S , Mourier G , Corringer PJ , Menez A |
| Ref : Journal de Physiologie (Paris) , 92 :490 , 1998 |
| PubMedID: |
| Title : Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha7 nicotinic receptor - Servent_1997_J.Biol.Chem_272_24279 |
| Author(s) : Servent D , Winckler-Dietrich V , Hu HY , Kessler P , Drevet P , Bertrand D , Menez A |
| Ref : Journal of Biological Chemistry , 272 :24279 , 1997 |
| Abstract : Servent_1997_J.Biol.Chem_272_24279 |
| ESTHER : Servent_1997_J.Biol.Chem_272_24279 |
| PubMedSearch : Servent_1997_J.Biol.Chem_272_24279 |
| PubMedID: 9305882 |