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| Title : Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer's Disease Mouse Model upon Irradiation - Scheiner_2022_J.Am.Chem.Soc__ |
| Author(s) : Scheiner M , Sink A , Hoffmann M , Vrigneau C , Endres E , Carles A , Sotriffer C , Maurice T , Decker M |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : Scheiner_2022_J.Am.Chem.Soc__ |
| ESTHER : Scheiner_2022_J.Am.Chem.Soc__ |
| PubMedSearch : Scheiner_2022_J.Am.Chem.Soc__ |
| PubMedID: 35138833 |
| Title : Azobioisosteres of Curcumin with Pronounced Activity against Amyloid Aggregation, Intracellular Oxidative Stress, and Neuroinflammation - Hofmann_2021_Chemistry_27_6015 |
| Author(s) : Hofmann J , Ginex T , Espargaro A , Scheiner M , Gunesch S , Arago M , Stigloher C , Sabate R , Luque FJ , Decker M |
| Ref : Chemistry , 27 :6015 , 2021 |
| Abstract : Hofmann_2021_Chemistry_27_6015 |
| ESTHER : Hofmann_2021_Chemistry_27_6015 |
| PubMedSearch : Hofmann_2021_Chemistry_27_6015 |
| PubMedID: 33666306 |
| Title : Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model - Scheiner_2021_J.Med.Chem_64_9302 |
| Author(s) : Scheiner M , Hoffmann M , He F , Poeta E , Chatonnet A , Monti B , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 64(13): :9302 , 2021 |
| Abstract : Scheiner_2021_J.Med.Chem_64_9302 |
| ESTHER : Scheiner_2021_J.Med.Chem_64_9302 |
| PubMedSearch : Scheiner_2021_J.Med.Chem_64_9302 |
| PubMedID: 34152756 |
| Title : From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects - Pont_2021_Eur.J.Med.Chem_225_113779 |
| Author(s) : Pont C , Ginex T , Grinan-Ferre C , Scheiner M , Mattellone A , Martinez N , Arce EM , Soriano-Fernandez Y , Naldi M , De Simone A , Barenys M , Gomez-Catalan J , Perez B , Sabate R , Andrisano V , Loza MI , Brea J , Bartolini M , Bolognesi ML , Decker M , Pallas M , Luque FJ , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113779 , 2021 |
| Abstract : Pont_2021_Eur.J.Med.Chem_225_113779 |
| ESTHER : Pont_2021_Eur.J.Med.Chem_225_113779 |
| PubMedSearch : Pont_2021_Eur.J.Med.Chem_225_113779 |
| PubMedID: 34418785 |
| Title : Photopharmacology on Acetylcholinesterase: Novel Photoswitchable Inhibitors with Improved Pharmacological Profiles - Scheiner_2021_ChemPhotoChem_5_149 |
| Author(s) : Scheiner M , Sink A , Spatz P , Endres E , Decker M |
| Ref : ChemPhotoChem , 5 :149 , 2021 |
| Abstract : Scheiner_2021_ChemPhotoChem_5_149 |
| ESTHER : Scheiner_2021_ChemPhotoChem_5_149 |
| PubMedSearch : Scheiner_2021_ChemPhotoChem_5_149 |
| PubMedID: |
| Title : Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo - Hofmann_2020_Chemistry_26_7299 |
| Author(s) : Hofmann J , Fayez S , Scheiner M , Hoffmann M , Oerter S , Appelt-Menzel A , Maher P , Maurice T , Bringmann G , Decker M |
| Ref : Chemistry , 26 :7299 , 2020 |
| Abstract : Hofmann_2020_Chemistry_26_7299 |
| ESTHER : Hofmann_2020_Chemistry_26_7299 |
| PubMedSearch : Hofmann_2020_Chemistry_26_7299 |
| PubMedID: 32358806 |
| Title : Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands - Rodriguez-Soacha_2019_Eur.J.Med.Chem_180_690 |
| Author(s) : Rodriguez-Soacha DA , Scheiner M , Decker M |
| Ref : Eur Journal of Medicinal Chemistry , 180 :690 , 2019 |
| Abstract : Rodriguez-Soacha_2019_Eur.J.Med.Chem_180_690 |
| ESTHER : Rodriguez-Soacha_2019_Eur.J.Med.Chem_180_690 |
| PubMedSearch : Rodriguez-Soacha_2019_Eur.J.Med.Chem_180_690 |
| PubMedID: 31401465 |
| Title : Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer's Disease Mouse Model - Hoffmann_2019_J.Med.Chem_62_9116 |
| Author(s) : Hoffmann M , Stiller C , Endres E , Scheiner M , Gunesch S , Sotriffer C , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 62 :9116 , 2019 |
| Abstract : Hoffmann_2019_J.Med.Chem_62_9116 |
| ESTHER : Hoffmann_2019_J.Med.Chem_62_9116 |
| PubMedSearch : Hoffmann_2019_J.Med.Chem_62_9116 |
| PubMedID: 31609115 |
| Title : Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo - Scheiner_2019_J.Med.Chem_62_9078 |
| Author(s) : Scheiner M , Dolles D , Gunesch S , Hoffmann M , Nabissi M , Marinelli O , Naldi M , Bartolini M , Petralla S , Poeta E , Monti B , Falkeis C , Vieth M , Hubner H , Gmeiner P , Maitra R , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 62 :9078 , 2019 |
| Abstract : Scheiner_2019_J.Med.Chem_62_9078 |
| ESTHER : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedSearch : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedID: 31609608 |
| Title : Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2 R Ligands To Combat Neurodegenerative Disorders - Dolles_2016_ChemMedChem_11_1270 |
| Author(s) : Dolles D , Nimczick M , Scheiner M , Ramler J , Stadtmuller P , Sawatzky E , Drakopoulos A , Sotriffer C , Wittmann HJ , Strasser A , Decker M |
| Ref : ChemMedChem , 11 :1270 , 2016 |
| Abstract : Dolles_2016_ChemMedChem_11_1270 |
| ESTHER : Dolles_2016_ChemMedChem_11_1270 |
| PubMedSearch : Dolles_2016_ChemMedChem_11_1270 |
| PubMedID: 26548365 |