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| Title : 1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling - Kasnanen_2013_Eur.J.Pharm.Sci_49_423 |
| Author(s) : Kasnanen H , Minkkila A , Taupila S , Patel JZ , Parkkari T , Lahtela-Kakkonen M , Saario SM , Nevalainen T , Poso A |
| Ref : Eur J Pharm Sci , 49 :423 , 2013 |
| Abstract : Kasnanen_2013_Eur.J.Pharm.Sci_49_423 |
| ESTHER : Kasnanen_2013_Eur.J.Pharm.Sci_49_423 |
| PubMedSearch : Kasnanen_2013_Eur.J.Pharm.Sci_49_423 |
| PubMedID: 23557840 |
| Gene_locus related to this paper: human-MGLL |
| Title : The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors - Savinainen_2012_Acta.Physiol.(Oxf)_204_267 |
| Author(s) : Savinainen JR , Saario SM , Laitinen JT |
| Ref : Acta Physiol (Oxf) , 204 :267 , 2012 |
| Abstract : Savinainen_2012_Acta.Physiol.(Oxf)_204_267 |
| ESTHER : Savinainen_2012_Acta.Physiol.(Oxf)_204_267 |
| PubMedSearch : Savinainen_2012_Acta.Physiol.(Oxf)_204_267 |
| PubMedID: 21418147 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Discovery and development of endocannabinoid-hydrolyzing enzyme inhibitors - Minkkila_2010_Curr.Top.Med.Chem_10_828 |
| Author(s) : Minkkila A , Saario SM , Nevalainen T |
| Ref : Curr Top Med Chem , 10 :828 , 2010 |
| Abstract : Minkkila_2010_Curr.Top.Med.Chem_10_828 |
| ESTHER : Minkkila_2010_Curr.Top.Med.Chem_10_828 |
| PubMedSearch : Minkkila_2010_Curr.Top.Med.Chem_10_828 |
| PubMedID: 20370710 |
| Title : Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors - |
| Author(s) : Minkkila A , Savinainen JR , Kasnanen H , Xhaard H , Nevalainen T , Laitinen JT , Poso A , Leppanen J , Saario SM |
| Ref : ChemMedChem , 4 :1253 , 2009 |
| PubMedID: 19472270 |
| Title : Design, synthesis, and in vitro evaluation of carbamate derivatives of 2-benzoxazolyl- and 2-benzothiazolyl-(3-hydroxyphenyl)-methanones as novel fatty acid amide hydrolase inhibitors - Myllymaki_2007_J.Med.Chem_50_4236 |
| Author(s) : Myllymaki MJ , Saario SM , Kataja AO , Castillo-Melendez JA , Nevalainen T , Juvonen RO , Jarvinen T , Koskinen AM |
| Ref : Journal of Medicinal Chemistry , 50 :4236 , 2007 |
| Abstract : Myllymaki_2007_J.Med.Chem_50_4236 |
| ESTHER : Myllymaki_2007_J.Med.Chem_50_4236 |
| PubMedSearch : Myllymaki_2007_J.Med.Chem_50_4236 |
| PubMedID: 17665899 |
| Title : Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors - Saario_2007_Basic.Clin.Pharmacol.Toxicol_101_287 |
| Author(s) : Saario SM , Laitinen JT |
| Ref : Basic Clin Pharmacol Toxicol , 101 :287 , 2007 |
| Abstract : Saario_2007_Basic.Clin.Pharmacol.Toxicol_101_287 |
| ESTHER : Saario_2007_Basic.Clin.Pharmacol.Toxicol_101_287 |
| PubMedSearch : Saario_2007_Basic.Clin.Pharmacol.Toxicol_101_287 |
| PubMedID: 17910610 |
| Title : Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system - Saario_2006_J.Med.Chem_49_4650 |
| Author(s) : Saario SM , Poso A , Juvonen RO , Jarvinen T , Salo-Ahen OM |
| Ref : Journal of Medicinal Chemistry , 49 :4650 , 2006 |
| Abstract : Saario_2006_J.Med.Chem_49_4650 |
| ESTHER : Saario_2006_J.Med.Chem_49_4650 |
| PubMedSearch : Saario_2006_J.Med.Chem_49_4650 |
| PubMedID: 16854070 |
| Title : Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes - Saario_2005_Chem.Biol_12_649 |
| Author(s) : Saario SM , Salo OM , Nevalainen T , Poso A , Laitinen JT , Jarvinen T , Niemi R |
| Ref : Chemical Biology , 12 :649 , 2005 |
| Abstract : Saario_2005_Chem.Biol_12_649 |
| ESTHER : Saario_2005_Chem.Biol_12_649 |
| PubMedSearch : Saario_2005_Chem.Biol_12_649 |
| PubMedID: 15975510 |
| Title : Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes - Saario_2004_Biochem.Pharmacol_67_1381 |
| Author(s) : Saario SM , Savinainen JR , Laitinen JT , Jarvinen T , Niemi R |
| Ref : Biochemical Pharmacology , 67 :1381 , 2004 |
| Abstract : Saario_2004_Biochem.Pharmacol_67_1381 |
| ESTHER : Saario_2004_Biochem.Pharmacol_67_1381 |
| PubMedSearch : Saario_2004_Biochem.Pharmacol_67_1381 |
| PubMedID: 15013854 |