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| Title : Effect of the acyl-group length on the chemoselectivity of the lipase-catalyzed acylation of propranolol-a computational study - Doerr_2021_J.Mol.Model_27_198 |
| Author(s) : Doerr M , Romero A , Daza MC |
| Ref : J Mol Model , 27 :198 , 2021 |
| Abstract : Doerr_2021_J.Mol.Model_27_198 |
| ESTHER : Doerr_2021_J.Mol.Model_27_198 |
| PubMedSearch : Doerr_2021_J.Mol.Model_27_198 |
| PubMedID: 34115202 |
| Gene_locus related to this paper: canar-LipB |
| Title : Highlights of ASS234: a novel and promising therapeutic agent for Alzheimer's disease therapy - Romero_2020_Neural.Regen.Res_15_30 |
| Author(s) : Romero A , Marco-Contelles J , Ramos E |
| Ref : Neural Regen Res , 15 :30 , 2020 |
| Abstract : Romero_2020_Neural.Regen.Res_15_30 |
| ESTHER : Romero_2020_Neural.Regen.Res_15_30 |
| PubMedSearch : Romero_2020_Neural.Regen.Res_15_30 |
| PubMedID: 31535639 |
| Title : New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer s disease endowed with neurogenic properties - Estrada-Valencia_2019_J.Enzyme.Inhib.Med.Chem_34_712 |
| Author(s) : Estrada-Valencia M , Herrera-Arozamena C , Perez C , Vina D , Morales-Garcia JA , Perez-Castillo A , Ramos E , Romero A , Laurini E , Pricl S , Rodriguez-Franco MI |
| Ref : J Enzyme Inhib Med Chem , 34 :712 , 2019 |
| Abstract : Estrada-Valencia_2019_J.Enzyme.Inhib.Med.Chem_34_712 |
| ESTHER : Estrada-Valencia_2019_J.Enzyme.Inhib.Med.Chem_34_712 |
| PubMedSearch : Estrada-Valencia_2019_J.Enzyme.Inhib.Med.Chem_34_712 |
| PubMedID: 31852270 |
| Title : QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy - Ramos_2019_Molecules_24_ |
| Author(s) : Ramos E , Palomino-Antolin A , Bartolini M , Iriepa I , Moraleda I , Diez-Iriepa D , Samadi A , Cortina CV , Chioua M , Egea J , Romero A , Marco-Contelles J |
| Ref : Molecules , 24 : , 2019 |
| Abstract : Ramos_2019_Molecules_24_ |
| ESTHER : Ramos_2019_Molecules_24_ |
| PubMedSearch : Ramos_2019_Molecules_24_ |
| PubMedID: 30999586 |
| Title : Neurotoxicity of organophosphate pesticides could reduce the ability of fish to escape predation under low doses of exposure - Sandoval-Herrera_2019_Sci.Rep_9_10530 |
| Author(s) : Sandoval-Herrera N , Mena F , Espinoza M , Romero A |
| Ref : Sci Rep , 9 :10530 , 2019 |
| Abstract : Sandoval-Herrera_2019_Sci.Rep_9_10530 |
| ESTHER : Sandoval-Herrera_2019_Sci.Rep_9_10530 |
| PubMedSearch : Sandoval-Herrera_2019_Sci.Rep_9_10530 |
| PubMedID: 31324839 |
| Title : Effect of Synergists on Deltamethrin Resistance in the Common Bed Bug (Hemiptera: Cimicidae) - Gonzalez-Morales_2019_J.Econ.Entomol_112_786 |
| Author(s) : Gonzalez-Morales MA , Romero A |
| Ref : J Econ Entomol , 112 :786 , 2019 |
| Abstract : Gonzalez-Morales_2019_J.Econ.Entomol_112_786 |
| ESTHER : Gonzalez-Morales_2019_J.Econ.Entomol_112_786 |
| PubMedSearch : Gonzalez-Morales_2019_J.Econ.Entomol_112_786 |
| PubMedID: 30535372 |
| Title : Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease - Estrada_2018_Eur.J.Med.Chem_156_534 |
| Author(s) : Estrada Valencia M , Herrera-Arozamena C , de Andres L , Perez C , Morales-Garcia JA , Perez-Castillo A , Ramos E , Romero A , Vina D , Yanez M , Laurini E , Pricl S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 156 :534 , 2018 |
| Abstract : Estrada_2018_Eur.J.Med.Chem_156_534 |
| ESTHER : Estrada_2018_Eur.J.Med.Chem_156_534 |
| PubMedSearch : Estrada_2018_Eur.J.Med.Chem_156_534 |
| PubMedID: 30025348 |
| Title : Recent Developments on Multi-Target-Directed Tacrines for Alzheimer's Disease. I. The Pyranotacrines - Romero_2017_Curr.Top.Med.Chem_17_3328 |
| Author(s) : Romero A , Marco-Contelles J |
| Ref : Curr Top Med Chem , 17 :3328 , 2017 |
| Abstract : Romero_2017_Curr.Top.Med.Chem_17_3328 |
| ESTHER : Romero_2017_Curr.Top.Med.Chem_17_3328 |
| PubMedSearch : Romero_2017_Curr.Top.Med.Chem_17_3328 |
| PubMedID: 29332586 |
| Title : The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease - Serrano_2017_J.Psychiatry.Neurosci_42_59 |
| Author(s) : Serrano MP , Herrero-Labrador R , Futch HS , Serrano J , Romero A , Fernandez AP , Samadi A , Unzeta M , Marco-Contelles J , Martinez-Murillo R |
| Ref : J Psychiatry Neurosci , 42 :59 , 2017 |
| Abstract : Serrano_2017_J.Psychiatry.Neurosci_42_59 |
| ESTHER : Serrano_2017_J.Psychiatry.Neurosci_42_59 |
| PubMedSearch : Serrano_2017_J.Psychiatry.Neurosci_42_59 |
| PubMedID: 27636528 |
| Title : ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy - Marco-Contelles_2016_Front.Neurosci_10_294 |
| Author(s) : Marco-Contelles J , Unzeta M , Bolea I , Esteban G , Ramsay RR , Romero A , Martinez-Murillo R , Carreiras MC , Ismaili L |
| Ref : Front Neurosci , 10 :294 , 2016 |
| Abstract : Marco-Contelles_2016_Front.Neurosci_10_294 |
| ESTHER : Marco-Contelles_2016_Front.Neurosci_10_294 |
| PubMedSearch : Marco-Contelles_2016_Front.Neurosci_10_294 |
| PubMedID: 27445665 |
| Title : Upregulation of Antioxidant Enzymes by ASS234, a Multitarget Directed Propargylamine for Alzheimer's Disease Therapy - |
| Author(s) : Ramos E , Romero A , Marco-Contelles J , Del Pino J |
| Ref : CNS Neurosci Ther , 22 :799 , 2016 |
| PubMedID: 27380946 |
| Title : New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties - Estrada_2016_Eur.J.Med.Chem_121_376 |
| Author(s) : Estrada M , Herrera-Arozamena C , Perez C , Vina D , Romero A , Morales-Garcia JA , Perez-Castillo A , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 121 :376 , 2016 |
| Abstract : Estrada_2016_Eur.J.Med.Chem_121_376 |
| ESTHER : Estrada_2016_Eur.J.Med.Chem_121_376 |
| PubMedSearch : Estrada_2016_Eur.J.Med.Chem_121_376 |
| PubMedID: 27267007 |
| Title : The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators - Benchekroun_2016_J.Med.Chem_59_9967 |
| Author(s) : Benchekroun M , Romero A , Egea J , Leon R , Michalska P , Buendia I , Jimeno ML , Jun D , Janockova J , Sepsova V , Soukup O , Bautista-Aguilera OM , Refouvelet B , Ouari O , Marco-Contelles J , Ismaili L |
| Ref : Journal of Medicinal Chemistry , 59 :9967 , 2016 |
| Abstract : Benchekroun_2016_J.Med.Chem_59_9967 |
| ESTHER : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedSearch : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedID: 27736061 |
| Title : High Levels of Resistance in the Common Bed Bug, Cimex lectularius (Hemiptera: Cimicidae), to Neonicotinoid Insecticides - Romero_2016_J.Med.Entomol_53_727 |
| Author(s) : Romero A , Anderson TD |
| Ref : Journal of Medical Entomology , 53 :727 , 2016 |
| Abstract : Romero_2016_J.Med.Entomol_53_727 |
| ESTHER : Romero_2016_J.Med.Entomol_53_727 |
| PubMedSearch : Romero_2016_J.Med.Entomol_53_727 |
| PubMedID: 26823499 |
| Title : Novel tacrine-grafted ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic Acid hybrids - Benchekroun_2015_ChemMedChem_10_523 |
| Author(s) : Benchekroun M , Bartolini M , Egea J , Romero A , Soriano E , Pudlo M , Luzet V , Andrisano V , Jimeno ML , Lopez MG , Wehle S , Gharbi T , Refouvelet B , de Andres L , Herrera-Arozamena C , Monti B , Bolognesi ML , Rodriguez-Franco MI , Decker M , Marco-Contelles J , Ismaili L |
| Ref : ChemMedChem , 10 :523 , 2015 |
| Abstract : Benchekroun_2015_ChemMedChem_10_523 |
| ESTHER : Benchekroun_2015_ChemMedChem_10_523 |
| PubMedSearch : Benchekroun_2015_ChemMedChem_10_523 |
| PubMedID: 25537267 |
| Title : Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease - Wang_2014_Eur.J.Med.Chem_80_543 |
| Author(s) : Wang L , Esteban G , Ojima M , Bautista-Aguilera OM , Inokuchi T , Moraleda I , Iriepa I , Samadi A , Youdim MB , Romero A , Soriano E , Herrero R , Fernandez Fernandez AP , Ricardo Martinez M , Marco-Contelles J , Unzeta M |
| Ref : Eur Journal of Medicinal Chemistry , 80 :543 , 2014 |
| Abstract : Wang_2014_Eur.J.Med.Chem_80_543 |
| ESTHER : Wang_2014_Eur.J.Med.Chem_80_543 |
| PubMedSearch : Wang_2014_Eur.J.Med.Chem_80_543 |
| PubMedID: 24813882 |
| Title : Wnt signaling pathway, a potential target for Alzheimer's disease treatment, is activated by a novel multitarget compound ASS234 - |
| Author(s) : Del Pino J , Ramos E , Aguilera OM , Marco-Contelles J , Romero A |
| Ref : CNS Neurosci Ther , 20 :568 , 2014 |
| PubMedID: 24712554 |
| Title : New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease - Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| Author(s) : Lopez-Iglesias B , Perez C , Morales-Garcia JA , Alonso-Gil S , Perez-Castillo A , Romero A , Lopez MG , Villarroya M , Conde S , Rodriguez-Franco MI |
| Ref : Journal of Medicinal Chemistry , 57 :3773 , 2014 |
| Abstract : Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| ESTHER : Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| PubMedSearch : Lopez-Iglesias_2014_J.Med.Chem_57_3773 |
| PubMedID: 24738476 |
| Title : Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease - Cherif_2014_Future.Med.Chem_6_1883 |
| Author(s) : Cherif O , Allouche F , Chabchoub F , Chioua M , Soriano E , Yanez M , Cacabelos R , Romero A , Lopez MG , Marco-Contelles J |
| Ref : Future Med Chem , 6 :1883 , 2014 |
| Abstract : Cherif_2014_Future.Med.Chem_6_1883 |
| ESTHER : Cherif_2014_Future.Med.Chem_6_1883 |
| PubMedSearch : Cherif_2014_Future.Med.Chem_6_1883 |
| PubMedID: 25495982 |
| Title : PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice - Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| Author(s) : Lorrio S , Romero A , Gonzalez-Lafuente L , Lajarin-Cuesta R , Martinez-Sanz FJ , Estrada M , Samadi A , Marco-Contelles J , Rodriguez-Franco MI , Villarroya M , Lopez MG , de los Rios C |
| Ref : ACS Chem Neurosci , 4 :1267 , 2013 |
| Abstract : Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| ESTHER : Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| PubMedSearch : Lorrio_2013_ACS.Chem.Neurosci_4_1267 |
| PubMedID: 23763493 |
| Title : Nontoxic and neuroprotective beta-naphthotacrines for Alzheimer's disease - Esquivias-Perez_2013_Chem.Res.Toxicol_26_986 |
| Author(s) : Esquivias-Perez M , Maalej E , Romero A , Chabchoub F , Samadi A , Marco-Contelles J , Oset-Gasque MJ |
| Ref : Chemical Research in Toxicology , 26 :986 , 2013 |
| Abstract : Esquivias-Perez_2013_Chem.Res.Toxicol_26_986 |
| ESTHER : Esquivias-Perez_2013_Chem.Res.Toxicol_26_986 |
| PubMedSearch : Esquivias-Perez_2013_Chem.Res.Toxicol_26_986 |
| PubMedID: 23676090 |
| Title : Structure-activity relationship of a new series of reversible dual monoacylglycerol lipase\/fatty acid amide hydrolase inhibitors - Cisneros_2012_J.Med.Chem_55_824 |
| Author(s) : Cisneros JA , Bjorklund E , Gonzalez-Gil I , Hu Y , Canales A , Medrano FJ , Romero A , Ortega-Gutierrez S , Fowler CJ , Lopez-Rodriguez ML |
| Ref : Journal of Medicinal Chemistry , 55 :824 , 2012 |
| Abstract : Cisneros_2012_J.Med.Chem_55_824 |
| ESTHER : Cisneros_2012_J.Med.Chem_55_824 |
| PubMedSearch : Cisneros_2012_J.Med.Chem_55_824 |
| PubMedID: 22185522 |
| Title : N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease - Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Romero A , Del Barrio L , Martin-de-Saavedra MD , Egea J , Leon R , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 46 :2224 , 2011 |
| Abstract : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| ESTHER : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedSearch : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedID: 21420206 |
| Title : Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by alpha7 and beta2* nicotinic stimulation - Del Barrio_2011_Toxicol.Sci_123_193 |
| Author(s) : Del Barrio L , Martin-de-Saavedra MD , Romero A , Parada E , Egea J , Avila J , McIntosh JM , Wonnacott S , Lopez MG |
| Ref : Toxicol Sci , 123 :193 , 2011 |
| Abstract : Del Barrio_2011_Toxicol.Sci_123_193 |
| ESTHER : Del Barrio_2011_Toxicol.Sci_123_193 |
| PubMedSearch : Del Barrio_2011_Toxicol.Sci_123_193 |
| PubMedID: 21715663 |
| Title : Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives - Silva_2011_Eur.J.Med.Chem_46_4676 |
| Author(s) : Silva D , Chioua M , Samadi A , Carmo Carreiras M , Jimeno ML , Mendes E , Rios Cde L , Romero A , Villarroya M , Lopez MG , Marco-Contelles J |
| Ref : Eur Journal of Medicinal Chemistry , 46 :4676 , 2011 |
| Abstract : Silva_2011_Eur.J.Med.Chem_46_4676 |
| ESTHER : Silva_2011_Eur.J.Med.Chem_46_4676 |
| PubMedSearch : Silva_2011_Eur.J.Med.Chem_46_4676 |
| PubMedID: 21715067 |
| Title : Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles - Samadi_2010_Bioorg.Med.Chem_18_5861 |
| Author(s) : Samadi A , Marco-Contelles J , Soriano E , Alvarez-Perez M , Chioua M , Romero A , Gonzalez-Lafuente L , Gandia L , Roda JM , Lopez MG , Villarroya M , Garcia AG , Rios Cde L |
| Ref : Bioorganic & Medicinal Chemistry , 18 :5861 , 2010 |
| Abstract : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| ESTHER : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| PubMedSearch : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| PubMedID: 20656495 |
| Title : Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives - de Los Rios_2010_J.Med.Chem_53_5129 |
| Author(s) : de los Rios C , Egea J , Marco-Contelles J , Leon R , Samadi A , Iriepa I , Moraleda I , Galvez E , Garcia AG , Lopez MG , Villarroya M , Romero A |
| Ref : Journal of Medicinal Chemistry , 53 :5129 , 2010 |
| Abstract : de Los Rios_2010_J.Med.Chem_53_5129 |
| ESTHER : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedSearch : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedID: 20575555 |
| Title : Insight into the Sialome of the Bed Bug, Cimex lectularius - Francischetti_2010_J.Proteome.Res_9_3820 |
| Author(s) : Francischetti IM , Calvo E , Andersen JF , Pham VM , Favreau AJ , Barbian KD , Romero A , Valenzuela JG , Ribeiro JM |
| Ref : J Proteome Res , 9 :3820 , 2010 |
| Abstract : Francischetti_2010_J.Proteome.Res_9_3820 |
| ESTHER : Francischetti_2010_J.Proteome.Res_9_3820 |
| PubMedSearch : Francischetti_2010_J.Proteome.Res_9_3820 |
| PubMedID: 20441151 |
| Title : Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells - Romero_2010_J.Pineal.Res_49_141 |
| Author(s) : Romero A , Egea J , Garcia AG , Lopez MG |
| Ref : J Pineal Res , 49 :141 , 2010 |
| Abstract : Romero_2010_J.Pineal.Res_49_141 |
| ESTHER : Romero_2010_J.Pineal.Res_49_141 |
| PubMedSearch : Romero_2010_J.Pineal.Res_49_141 |
| PubMedID: 20536682 |
| Title : Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family - Medrano_1998_EMBO.J_17_1 |
| Author(s) : Medrano FJ , Alonso J , Garcia JL , Romero A , Bode W , Gomis-Ruth FX |
| Ref : EMBO Journal , 17 :1 , 1998 |
| Abstract : Medrano_1998_EMBO.J_17_1 |
| ESTHER : Medrano_1998_EMBO.J_17_1 |
| PubMedSearch : Medrano_1998_EMBO.J_17_1 |
| PubMedID: 9427736 |
| Gene_locus related to this paper: xanca-impep |