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| Title : Focused rational iterative site-specific mutagenesis (FRISM) - Li_2020_Methods.Enzymol_643_225 |
| Author(s) : Li D , Wu Q , Reetz MT |
| Ref : Methods Enzymol , 643 :225 , 2020 |
| Abstract : Li_2020_Methods.Enzymol_643_225 |
| ESTHER : Li_2020_Methods.Enzymol_643_225 |
| PubMedSearch : Li_2020_Methods.Enzymol_643_225 |
| PubMedID: 32896283 |
| Title : Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters - Xu_2019_J.Am.Chem.Soc_141_7934 |
| Author(s) : Xu J , Cen Y , Singh W , Fan J , Wu L , Lin X , Zhou J , Huang M , Reetz MT , Wu Q |
| Ref : Journal of the American Chemical Society , 141 :7934 , 2019 |
| Abstract : Xu_2019_J.Am.Chem.Soc_141_7934 |
| ESTHER : Xu_2019_J.Am.Chem.Soc_141_7934 |
| PubMedSearch : Xu_2019_J.Am.Chem.Soc_141_7934 |
| PubMedID: 31023008 |
| Gene_locus related to this paper: canar-LipB |
| Title : Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution - Cen_2019_Nat.Commun_10_3198 |
| Author(s) : Cen Y , Singh W , Arkin M , Moody TS , Huang M , Zhou J , Wu Q , Reetz MT |
| Ref : Nat Commun , 10 :3198 , 2019 |
| Abstract : Cen_2019_Nat.Commun_10_3198 |
| ESTHER : Cen_2019_Nat.Commun_10_3198 |
| PubMedSearch : Cen_2019_Nat.Commun_10_3198 |
| PubMedID: 31324776 |
| Gene_locus related to this paper: canar-LipB |
| Title : Directed Evolution of Artificial Metalloenzymes: A Universal Means to Tune the Selectivity of Transition Metal Catalysts? - Reetz_2019_Acc.Chem.Res_52_336 |
| Author(s) : Reetz MT |
| Ref : Acc Chem Res , 52 :336 , 2019 |
| Abstract : Reetz_2019_Acc.Chem.Res_52_336 |
| ESTHER : Reetz_2019_Acc.Chem.Res_52_336 |
| PubMedSearch : Reetz_2019_Acc.Chem.Res_52_336 |
| PubMedID: 30689339 |
| Title : A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes - Cadet_2018_Sci.Rep_8_16757 |
| Author(s) : Cadet F , Fontaine N , Li G , Sanchis J , Ng Fuk Chong M , Pandjaitan R , Vetrivel I , Offmann B , Reetz MT |
| Ref : Sci Rep , 8 :16757 , 2018 |
| Abstract : Cadet_2018_Sci.Rep_8_16757 |
| ESTHER : Cadet_2018_Sci.Rep_8_16757 |
| PubMedSearch : Cadet_2018_Sci.Rep_8_16757 |
| PubMedID: 30425279 |
| Title : (1)H, (13)C and (15)N resonance assignments of wild-type Bacillus subtilis Lipase A and its mutant evolved towards thermostability - Augustyniak_2013_Biomol.NMR.Assign_7_249 |
| Author(s) : Augustyniak W , Wienk H , Boelens R , Reetz MT |
| Ref : Biomol NMR Assign , 7 :249 , 2013 |
| Abstract : Augustyniak_2013_Biomol.NMR.Assign_7_249 |
| ESTHER : Augustyniak_2013_Biomol.NMR.Assign_7_249 |
| PubMedSearch : Augustyniak_2013_Biomol.NMR.Assign_7_249 |
| PubMedID: 22996591 |
| Title : Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm - Feng_2012_Chemistry_18_5646 |
| Author(s) : Feng X , Sanchis J , Reetz MT , Rabitz H |
| Ref : Chemistry , 18 :5646 , 2012 |
| Abstract : Feng_2012_Chemistry_18_5646 |
| ESTHER : Feng_2012_Chemistry_18_5646 |
| PubMedSearch : Feng_2012_Chemistry_18_5646 |
| PubMedID: 22434591 |
| Title : Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention - Augustyniak_2012_Protein.Sci_21_487 |
| Author(s) : Augustyniak W , Brzezinska AA , Pijning T , Wienk H , Boelens R , Dijkstra BW , Reetz MT |
| Ref : Protein Science , 21 :487 , 2012 |
| Abstract : Augustyniak_2012_Protein.Sci_21_487 |
| ESTHER : Augustyniak_2012_Protein.Sci_21_487 |
| PubMedSearch : Augustyniak_2012_Protein.Sci_21_487 |
| PubMedID: 22267088 |
| Gene_locus related to this paper: bacsu-lip |
| Title : Revisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis - Prasad_2011_Chemphyschem_12_1550 |
| Author(s) : Prasad S , Bocola M , Reetz MT |
| Ref : Chemphyschem , 12 :1550 , 2011 |
| Abstract : Prasad_2011_Chemphyschem_12_1550 |
| ESTHER : Prasad_2011_Chemphyschem_12_1550 |
| PubMedSearch : Prasad_2011_Chemphyschem_12_1550 |
| PubMedID: 21472964 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution - Reetz_2011_Chembiochem_12_1529 |
| Author(s) : Reetz MT , Zheng H |
| Ref : Chembiochem , 12 :1529 , 2011 |
| Abstract : Reetz_2011_Chembiochem_12_1529 |
| ESTHER : Reetz_2011_Chembiochem_12_1529 |
| PubMedSearch : Reetz_2011_Chembiochem_12_1529 |
| PubMedID: 21567703 |
| Gene_locus related to this paper: aspa1-aneh |
| Title : Manipulating the stereoselectivity of limonene epoxide hydrolase by directed evolution based on iterative saturation mutagenesis - Zheng_2010_J.Am.Chem.Soc_132_15744 |
| Author(s) : Zheng H , Reetz MT |
| Ref : Journal of the American Chemical Society , 132 :15744 , 2010 |
| Abstract : Zheng_2010_J.Am.Chem.Soc_132_15744 |
| ESTHER : Zheng_2010_J.Am.Chem.Soc_132_15744 |
| PubMedSearch : Zheng_2010_J.Am.Chem.Soc_132_15744 |
| PubMedID: 20958062 |
| Title : Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method - Reetz_2010_Chem.Commun.(Camb)_46_8657 |
| Author(s) : Reetz MT , Soni P , Fernandez L , Gumulya Y , Carballeira JD |
| Ref : Chem Commun (Camb) , 46 :8657 , 2010 |
| Abstract : Reetz_2010_Chem.Commun.(Camb)_46_8657 |
| ESTHER : Reetz_2010_Chem.Commun.(Camb)_46_8657 |
| PubMedSearch : Reetz_2010_Chem.Commun.(Camb)_46_8657 |
| PubMedID: 20957255 |
| Title : Knowledge-guided laboratory evolution of protein thermolability - Reetz_2009_Biotechnol.Bioeng_102_1712 |
| Author(s) : Reetz MT , Soni P , Fernandez L |
| Ref : Biotechnol Bioeng , 102 :1712 , 2009 |
| Abstract : Reetz_2009_Biotechnol.Bioeng_102_1712 |
| ESTHER : Reetz_2009_Biotechnol.Bioeng_102_1712 |
| PubMedSearch : Reetz_2009_Biotechnol.Bioeng_102_1712 |
| PubMedID: 19072845 |
| Title : Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage - Reetz_2009_J.Am.Chem.Soc_131_7334 |
| Author(s) : Reetz MT , Bocola M , Wang LW , Sanchis J , Cronin A , Arand M , Zou J , Archelas A , Bottalla AL , Naworyta A , Mowbray SL |
| Ref : Journal of the American Chemical Society , 131 :7334 , 2009 |
| Abstract : Reetz_2009_J.Am.Chem.Soc_131_7334 |
| ESTHER : Reetz_2009_J.Am.Chem.Soc_131_7334 |
| PubMedSearch : Reetz_2009_J.Am.Chem.Soc_131_7334 |
| PubMedID: 19469578 |
| Gene_locus related to this paper: aspni-hyl1 |
| Title : A genetic selection system for evolving enantioselectivity of enzymes - Reetz_2008_Chem.Commun.(Camb)__5502 |
| Author(s) : Reetz MT , Hobenreich H , Soni P , Fernandez L |
| Ref : Chem Commun (Camb) , :5502 , 2008 |
| Abstract : Reetz_2008_Chem.Commun.(Camb)__5502 |
| ESTHER : Reetz_2008_Chem.Commun.(Camb)__5502 |
| PubMedSearch : Reetz_2008_Chem.Commun.(Camb)__5502 |
| PubMedID: 18997932 |
| Gene_locus related to this paper: canar-LipB |
| Title : Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates - Sanchis_2008_Appl.Microbiol.Biotechnol_81_387 |
| Author(s) : Sanchis J , Fernandez L , Carballeira JD , Drone J , Gumulya Y , Hobenreich H , Kahakeaw D , Kille S , Lohmer R , Peyralans JJ , Podtetenieff J , Prasad S , Soni P , Taglieber A , Wu S , Zilly FE , Reetz MT |
| Ref : Applied Microbiology & Biotechnology , 81 :387 , 2008 |
| Abstract : Sanchis_2008_Appl.Microbiol.Biotechnol_81_387 |
| ESTHER : Sanchis_2008_Appl.Microbiol.Biotechnol_81_387 |
| PubMedSearch : Sanchis_2008_Appl.Microbiol.Biotechnol_81_387 |
| PubMedID: 18820909 |
| Title : Learning from directed evolution: Further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity - Reetz_2007_Chembiochem_8_106 |
| Author(s) : Reetz MT , Puls M , Carballeira JD , Vogel A , Jaeger KE , Eggert T , Thiel W , Bocola M , Otte N |
| Ref : Chembiochem , 8 :106 , 2007 |
| Abstract : Reetz_2007_Chembiochem_8_106 |
| ESTHER : Reetz_2007_Chembiochem_8_106 |
| PubMedSearch : Reetz_2007_Chembiochem_8_106 |
| PubMedID: 17133645 |
| Title : Expanding the substrate scope of enzymes: combining mutations obtained by CASTing - Reetz_2006_Chemistry_12_6031 |
| Author(s) : Reetz MT , Carballeira JD , Peyralans J , Hobenreich H , Maichele A , Vogel A |
| Ref : Chemistry , 12 :6031 , 2006 |
| Abstract : Reetz_2006_Chemistry_12_6031 |
| ESTHER : Reetz_2006_Chemistry_12_6031 |
| PubMedSearch : Reetz_2006_Chemistry_12_6031 |
| PubMedID: 16789057 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space - Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236 |
| Author(s) : Reetz MT , Wang LW , Bocola M |
| Ref : Angew Chem Int Ed Engl , 45 :1236 , 2006 |
| Abstract : Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236 |
| ESTHER : Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236 |
| PubMedSearch : Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236 |
| PubMedID: 16411254 |
| Gene_locus related to this paper: aspni-hyl1 |
| Title : Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection - Droge_2006_Chembiochem_7_149 |
| Author(s) : Droge MJ , Boersma YL , van Pouderoyen G , Vrenken TE , Ruggeberg CJ , Reetz MT , Dijkstra BW , Quax WJ |
| Ref : Chembiochem , 7 :149 , 2006 |
| Abstract : Droge_2006_Chembiochem_7_149 |
| ESTHER : Droge_2006_Chembiochem_7_149 |
| PubMedSearch : Droge_2006_Chembiochem_7_149 |
| PubMedID: 16342303 |
| Gene_locus related to this paper: bacsu-lip |
| Title : Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test - Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 |
| Author(s) : Reetz MT , Bocola M , Carballeira JD , Zha D , Vogel A |
| Ref : Angew Chem Int Ed Engl , 44 :4192 , 2005 |
| Abstract : Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 |
| ESTHER : Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 |
| PubMedSearch : Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 |
| PubMedID: 15929154 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Multiplex-PCR-based recombination as a novel high-fidelity method for directed evolution - Eggert_2005_Chembiochem_6_1062 |
| Author(s) : Eggert T , Funke SA , Rao NM , Acharya P , Krumm H , Reetz MT , Jaeger KE |
| Ref : Chembiochem , 6 :1062 , 2005 |
| Abstract : Eggert_2005_Chembiochem_6_1062 |
| ESTHER : Eggert_2005_Chembiochem_6_1062 |
| PubMedSearch : Eggert_2005_Chembiochem_6_1062 |
| PubMedID: 15880674 |
| Title : Liquid poly(ethylene glycol) and supercritical carbon dioxide as a biphasic solvent system for lipase-catalyzed esterification - Reetz_2004_Chem.Commun.(Camb)__2750 |
| Author(s) : Reetz MT , Wiesenhofer W |
| Ref : Chem Commun (Camb) , :2750 , 2004 |
| Abstract : Reetz_2004_Chem.Commun.(Camb)__2750 |
| ESTHER : Reetz_2004_Chem.Commun.(Camb)__2750 |
| PubMedSearch : Reetz_2004_Chem.Commun.(Camb)__2750 |
| PubMedID: 15568099 |
| Title : Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity - Bocola_2004_Chembiochem_5_214 |
| Author(s) : Bocola M , Otte N , Jaeger KE , Reetz MT , Thiel W |
| Ref : Chembiochem , 5 :214 , 2004 |
| Abstract : Bocola_2004_Chembiochem_5_214 |
| ESTHER : Bocola_2004_Chembiochem_5_214 |
| PubMedSearch : Bocola_2004_Chembiochem_5_214 |
| PubMedID: 14760743 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications - Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 |
| Author(s) : Reetz MT |
| Ref : Proc Natl Acad Sci U S A , 101 :5716 , 2004 |
| Abstract : Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 |
| ESTHER : Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 |
| PubMedSearch : Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 |
| PubMedID: 15079053 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution - Reetz_2004_Org.Lett_6_177 |
| Author(s) : Reetz MT , Torre C , Eipper A , Lohmer R , Hermes M , Brunner B , Maichele A , Bocola M , Arand M , Cronin A , Genzel Y , Archelas A , Furstoss R |
| Ref : Org Lett , 6 :177 , 2004 |
| Abstract : Reetz_2004_Org.Lett_6_177 |
| ESTHER : Reetz_2004_Org.Lett_6_177 |
| PubMedSearch : Reetz_2004_Org.Lett_6_177 |
| PubMedID: 14723522 |
| Gene_locus related to this paper: aspni-hyl1 |
| Title : Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor - Droge_2003_J.Biotechnol_101_19 |
| Author(s) : Droge MJ , Ruggeberg CJ , van der Sloot AM , Schimmel J , Dijkstra DS , Verhaert RM , Reetz MT , Quax WJ |
| Ref : J Biotechnol , 101 :19 , 2003 |
| Abstract : Droge_2003_J.Biotechnol_101_19 |
| ESTHER : Droge_2003_J.Biotechnol_101_19 |
| PubMedSearch : Droge_2003_J.Biotechnol_101_19 |
| PubMedID: 12523966 |
| Title : Lipases as practical biocatalysts - Reetz_2002_Curr.Opin.Chem.Biol_6_145 |
| Author(s) : Reetz MT |
| Ref : Curr Opin Chemical Biology , 6 :145 , 2002 |
| Abstract : Reetz_2002_Curr.Opin.Chem.Biol_6_145 |
| ESTHER : Reetz_2002_Curr.Opin.Chem.Biol_6_145 |
| PubMedSearch : Reetz_2002_Curr.Opin.Chem.Biol_6_145 |
| PubMedID: 12038997 |
| Title : Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis - |
| Author(s) : Reetz MT , Wilensek S , Zha D , Jaeger KE |
| Ref : Angew Chem Int Ed Engl , 40 :3589 , 2001 |
| PubMedID: 11592190 |
| Title : Directed evolution and the creation of enantioselective biocatalysts - Jaeger_2001_Appl.Microbiol.Biotechnol_55_519 |
| Author(s) : Jaeger KE , Eggert T , Eipper A , Reetz MT |
| Ref : Applied Microbiology & Biotechnology , 55 :519 , 2001 |
| Abstract : Jaeger_2001_Appl.Microbiol.Biotechnol_55_519 |
| ESTHER : Jaeger_2001_Appl.Microbiol.Biotechnol_55_519 |
| PubMedSearch : Jaeger_2001_Appl.Microbiol.Biotechnol_55_519 |
| PubMedID: 11414315 |
| Title : Application of directed evolution in the development of enantioselective enzymes - Reetz_2000_Pure.Appl.Chem_72_1615 |
| Author(s) : Reetz MT |
| Ref : Pure Appl Chem , 72 :1615 , 2000 |
| Abstract : Reetz_2000_Pure.Appl.Chem_72_1615 |
| ESTHER : Reetz_2000_Pure.Appl.Chem_72_1615 |
| PubMedSearch : Reetz_2000_Pure.Appl.Chem_72_1615 |
| PubMedID: |
| Title : Directed evolution of an enantioselective lipase - Liebeton_2000_Chem.Biol_7_709 |
| Author(s) : Liebeton K , Zonta A , Schimossek K , Nardini M , Lang D , Dijkstra BW , Reetz MT , Jaeger KE |
| Ref : Chemical Biology , 7 :709 , 2000 |
| Abstract : Liebeton_2000_Chem.Biol_7_709 |
| ESTHER : Liebeton_2000_Chem.Biol_7_709 |
| PubMedSearch : Liebeton_2000_Chem.Biol_7_709 |
| PubMedID: 10980451 |
| Title : Directed evolution of enantioselective enzymes for organic chemistry - Jaeger_2000_Curr.Opin.Chem.Biol_4_68 |
| Author(s) : Jaeger KE , Reetz MT |
| Ref : Curr Opin Chemical Biology , 4 :68 , 2000 |
| Abstract : Jaeger_2000_Curr.Opin.Chem.Biol_4_68 |
| ESTHER : Jaeger_2000_Curr.Opin.Chem.Biol_4_68 |
| PubMedSearch : Jaeger_2000_Curr.Opin.Chem.Biol_4_68 |
| PubMedID: 10679373 |
| Title : Enantioselective enzymes for organic synthesis created by directed evolution - Reetz_2000_Chemistry_6_407 |
| Author(s) : Reetz MT , Jaeger KE |
| Ref : Chemistry , 6 :407 , 2000 |
| Abstract : Reetz_2000_Chemistry_6_407 |
| ESTHER : Reetz_2000_Chemistry_6_407 |
| PubMedSearch : Reetz_2000_Chemistry_6_407 |
| PubMedID: 10747404 |
| Title : Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases - Jaeger_1999_Annu.Rev.Microbiol_53_315 |
| Author(s) : Jaeger KE , Dijkstra BW , Reetz MT |
| Ref : Annu Rev Microbiol , 53 :315 , 1999 |
| Abstract : Jaeger_1999_Annu.Rev.Microbiol_53_315 |
| ESTHER : Jaeger_1999_Annu.Rev.Microbiol_53_315 |
| PubMedSearch : Jaeger_1999_Annu.Rev.Microbiol_53_315 |
| PubMedID: 10547694 |
| Title : Microbial lipases form versatile tools for biotechnology - Jaeger_1998_Trends.Biotechnol_16_396 |
| Author(s) : Jaeger KE , Reetz MT |
| Ref : Trends Biotechnol , 16 :396 , 1998 |
| Abstract : Jaeger_1998_Trends.Biotechnol_16_396 |
| ESTHER : Jaeger_1998_Trends.Biotechnol_16_396 |
| PubMedSearch : Jaeger_1998_Trends.Biotechnol_16_396 |
| PubMedID: 9744114 |
| Title : Overexpression, immobilization and biotechnological application of Pseudomonas lipases - Reetz_1998_Chem.Phys.Lipids_93_3 |
| Author(s) : Reetz MT , Jaeger KE |
| Ref : Chemistry & Physic of Lipids , 93 :3 , 1998 |
| Abstract : Reetz_1998_Chem.Phys.Lipids_93_3 |
| ESTHER : Reetz_1998_Chem.Phys.Lipids_93_3 |
| PubMedSearch : Reetz_1998_Chem.Phys.Lipids_93_3 |
| PubMedID: 9720245 |