Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
Title : Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Pei_2006_J.Med.Chem_49_6439 |
Author(s) : Pei Z , Li X , von Geldern TW , Madar DJ , Longenecker K , Yong H , Lubben TH , Stewart KD , Zinker BA , Backes BJ , Judd AS , Mulhern M , Ballaron SJ , Stashko MA , Mika AK , Beno DW , Reinhart GA , Fryer RM , Preusser LC , Kempf-Grote AJ , Sham HL , Trevillyan JM |
Ref : Journal of Medicinal Chemistry , 49 :6439 , 2006 |
Abstract : Pei_2006_J.Med.Chem_49_6439 |
ESTHER : Pei_2006_J.Med.Chem_49_6439 |
PubMedSearch : Pei_2006_J.Med.Chem_49_6439 |
PubMedID: 17064063 |
Gene_locus related to this paper: human-DPP4 |
Title : ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders - Rueter_2004_CNS.Drug.Rev_10_167 |
Author(s) : Rueter LE , Anderson DJ , Briggs CA , Donnelly-Roberts D , Gintant GA , Gopalakrishnan M , Lin NH , Osinski MA , Reinhart GA , Buckley MJ , Martin RL , McDermott JS , Preusser LC , Seifert TR , Su Z , Cox BF , Decker MW , Sullivan JP |
Ref : CNS Drug Rev , 10 :167 , 2004 |
Abstract : Rueter_2004_CNS.Drug.Rev_10_167 |
ESTHER : Rueter_2004_CNS.Drug.Rev_10_167 |
PubMedSearch : Rueter_2004_CNS.Drug.Rev_10_167 |
PubMedID: 15179445 |