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| Title : (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrr olidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor - Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| Author(s) : Ammirati MJ , Andrews KM , Boyer DD , Brodeur AM , Danley DE , Doran SD , Hulin B , Liu S , McPherson RK , Orena SJ , Parker JC , Polivkova J , Qiu X , Soglia CB , Treadway JL , VanVolkenburg MA , Wilder DC , Piotrowski DW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :1991 , 2009 |
| Abstract : Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| ESTHER : Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| PubMedSearch : Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| PubMedID: 19275964 |
| Gene_locus related to this paper: human-DPP4 |
| Title : cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization - Wright_2006_J.Med.Chem_49_3068 |
| Author(s) : Wright SW , Ammirati MJ , Andrews KM , Brodeur AM , Danley DE , Doran SD , Lillquist JS , McClure LD , McPherson RK , Orena SJ , Parker JC , Polivkova J , Qiu X , Soeller WC , Soglia CB , Treadway JL , VanVolkenburg MA , Wang H , Wilder DC , Olson TV |
| Ref : Journal of Medicinal Chemistry , 49 :3068 , 2006 |
| Abstract : Wright_2006_J.Med.Chem_49_3068 |
| ESTHER : Wright_2006_J.Med.Chem_49_3068 |
| PubMedSearch : Wright_2006_J.Med.Chem_49_3068 |
| PubMedID: 16722626 |