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Author Report for: Perez C

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    Title: Using underwater currents as an occupational enrichment method to improve the stress status in rainbow trout
    Villalba AM, De la Llave-Propin A, de la Fuente J, Perez C, de Chavarri EG, Diaz MT, Cabezas A, Gonzalez-Garoz R, Torrent F and Bermejo-Poza R <1 more author(s)>
    Ref: Fish Physiol Biochem, :, 2023 : PubMed

            

    Title: Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
    Codony S, Entrena JM, Calvo-Tusell C, Jora B, Gonzalez-Cano R, Osuna S, Corpas R, Morisseau C, Perez B and Vazquez S <13 more author(s)>
    Ref: Journal of Medicinal Chemistry, 65:13660, 2022 : PubMed

            

    Title: Multitarget drugs as potential therapeutic agents for alzheimer's disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors
    Gonzalez-Naranjo P, Perez C, Gonzalez-Sanchez M, Gironda-Martinez A, Ulzurrun E, Bartolome F, Rubio-Fernandez M, Martin-Requero A, Campillo NE, Paez JA
    Ref: J Enzyme Inhib Med Chem, 37:2348, 2022 : PubMed

            

    Title: From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
    Codony S, Calvo-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Perez C, Rodriguez-Franco MI and Vazquez S <8 more author(s)>
    Ref: Journal of Medicinal Chemistry, :, 2021 : PubMed

            

    Title: The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage
    Jin N, Matter WF, Michael LF, Qian Y, Gheyi T, Cano L, Perez C, Lafuente C, Broughton HB, Espada A
    Ref: ACS Chemical Biology, :, 2021 : PubMed

            

    Title: 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis
    Codony S, Pujol E, Pizarro J, Feixas F, Valverde E, Loza MI, Brea JM, Saez E, Oyarzabal J and Vazquez S <9 more author(s)>
    Ref: Journal of Medicinal Chemistry, 63:9237, 2020 : PubMed

            

    Title: Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations
    Nunez-Borque E, Gonzalez-Naranjo P, Bartolome F, Alquezar C, Reinares-Sebastian A, Perez C, Ceballos ML, Paez JA, Campillo NE, Martin-Requero A
    Ref: Molecular Neurobiology, :, 2020 : PubMed

            

    Title: Physio-metabolic response of rainbow trout during prolonged food deprivation before slaughter
    Bermejo-Poza R, Fernandez-Muela M, de la Fuente J, Perez C, de Chavarri EG, Diaz MT, Torrent F, Villarroel M
    Ref: Fish Physiol Biochem, 45:253, 2019 : PubMed

            

    Title: New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer s disease endowed with neurogenic properties
    Estrada-Valencia M, Herrera-Arozamena C, Perez C, Vina D, Morales-Garcia JA, Perez-Castillo A, Ramos E, Romero A, Laurini E and Rodriguez-Franco MI <1 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 34:712, 2019 : PubMed

            

    Title: Indazolylketones as new multitarget cannabinoid drugs
    Gonzalez-Naranjo P, Perez-Macias N, Perez C, Roca C, Vaca G, Giron R, Sanchez-Robles E, Martin-Fontelles MI, de Ceballos ML and Paez JA <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 166:90, 2019 : PubMed

            

    Title: Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease
    de Andrade P, Mantoani SP, Goncalves Nunes PS, Magadan CR, Perez C, Xavier DJ, Hojo ETS, Campillo NE, Martinez A, Carvalho I
    Ref: Bioorganic & Medicinal Chemistry, 27:931, 2019 : PubMed

            

    Title: Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors
    Chierrito TPC, Pedersoli-Mantoani S, Roca C, Sebastian-Perez V, Martinez-Gonzalez L, Perez DI, Perez C, Canales A, Canada FJ and Martinez A <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 145:431, 2018 : PubMed

            

    Title: Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease
    Del Cerro P, Alquezar C, Bartolome F, Gonzalez-Naranjo P, Perez C, Carro E, Paez JA, Campillo NE, Martin-Requero A
    Ref: CNS Drugs, 32:579, 2018 : PubMed

            

    Title: Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease
    Estrada Valencia M, Herrera-Arozamena C, de Andres L, Perez C, Morales-Garcia JA, Perez-Castillo A, Ramos E, Romero A, Vina D and Rodriguez-Franco MI <3 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 156:534, 2018 : PubMed

            

    Title: Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors
    Reis J, Cagide F, Valencia ME, Teixeira J, Bagetta D, Perez C, Uriarte E, Oliveira PJ, Ortuso F and Borges F <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 158:781, 2018 : PubMed

            

    Title: Identification of new allosteric sites and modulators of AChE through computational and experimental tools
    Roca C, Requena C, Sebastian-Perez V, Malhotra S, Radoux C, Perez C, Martinez A, Antonio Paez J, Blundell TL, Campillo NE
    Ref: J Enzyme Inhib Med Chem, 33:1034, 2018 : PubMed

            

    Title: From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease
    Chierrito TPC, Mantoani SP, Roca C, Requena C, Sebastian-Perez V, Castillo WO, Moreira NCS, Perez C, Sakamoto-Hojo ET and Carvalho I <5 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 139:773, 2017 : PubMed

            

    Title: 3-(Benzyloxy)-1-(5-[18F]fluoropentyl)-5-nitro-1H-indazole: a PET radiotracer to measure acetylcholinesterase in brain
    Fernandez S, Giglio J, Reyes AL, Damian A, Perez C, Perez DI, Gonzalez M, Oliver P, Rey A and Cerecetto H <1 more author(s)>
    Ref: Future Med Chem, 9:983, 2017 : PubMed

            

    Title: Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia
    Monjas L, Arce MP, Leon R, Egea J, Perez C, Villarroya M, Lopez MG, Gil C, Conde S, Rodriguez-Franco MI
    Ref: Eur Journal of Medicinal Chemistry, 130:60, 2017 : PubMed

            

    Title: Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets
    Chlebek J, De Simone A, Hostalkova A, Opletal L, Perez C, Perez DI, Havlikova L, Cahlikova L, Andrisano V
    Ref: Fitoterapia, 109:241, 2016 : PubMed

            

    Title: New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties
    Estrada M, Herrera-Arozamena C, Perez C, Vina D, Romero A, Morales-Garcia JA, Perez-Castillo A, Rodriguez-Franco MI
    Ref: Eur Journal of Medicinal Chemistry, 121:376, 2016 : PubMed

            

    Title: New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with sigma-1 agonism and beta-secretase inhibition
    Estrada M, Perez C, Soriano E, Laurini E, Romano M, Pricl S, Morales-Garcia JA, Perez-Castillo A, Rodriguez-Franco MI
    Ref: Future Med Chem, 8:1191, 2016 : PubMed

            

    Title: Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease
    Gonzalez-Naranjo P, Perez-Macias N, Campillo NE, Perez C, Aran VJ, Giron R, Sanchez-Robles E, Martin MI, Gomez-Canas M and Paez JA <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 73:56, 2014 : PubMed

            

    Title: New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease
    Lopez-Iglesias B, Perez C, Morales-Garcia JA, Alonso-Gil S, Perez-Castillo A, Romero A, Lopez MG, Villarroya M, Conde S, Rodriguez-Franco MI
    Ref: Journal of Medicinal Chemistry, 57:3773, 2014 : PubMed

            

    Title: Multipotent, permeable drug ASS234 inhibits Abeta aggregation, possesses antioxidant properties and protects from Abeta-induced apoptosis in vitro
    Bolea I, Gella A, Monjas L, Perez C, Rodriguez-Franco MI, Marco-Contelles J, Samadi A, Unzeta M
    Ref: Curr Alzheimer Res, 10:797, 2013 : PubMed

            

    Title: Multitarget cannabinoids as novel strategy for Alzheimer disease
    Gonzalez-Naranjo P, Campillo NE, Perez C, Paez JA
    Ref: Curr Alzheimer Res, 10:229, 2013 : PubMed

            

    Title: Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease
    Samadi A, de la Fuente Revenga M, Perez C, Iriepa I, Moraleda I, Rodriguez-Franco MI, Marco-Contelles J
    Ref: Eur Journal of Medicinal Chemistry, 67:64, 2013 : PubMed

            

    Title: Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-beta-induced neurotoxicity
    Silva D, Chioua M, Samadi A, Agostinho P, Garcao P, Lajarin-Cuesta R, de los Rios C, Iriepa I, Moraleda I and Carmo Carreiras M <5 more author(s)>
    Ref: ACS Chem Neurosci, 4:547, 2013 : PubMed

            

    Title: New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and beta-amyloid-reducing properties
    Fernandez-Bachiller MI, Perez C, Monjas L, Rademann J, Rodriguez-Franco MI
    Ref: Journal of Medicinal Chemistry, 55:1303, 2012 : PubMed

            

    Title: Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling
    Samadi A, Estrada M, Perez C, Rodriguez-Franco MI, Iriepa I, Moraleda I, Chioua M, Marco-Contelles J
    Ref: Eur Journal of Medicinal Chemistry, 57C:296, 2012 : PubMed

            

    Title: N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease
    Gonzalez-Munoz GC, Arce MP, Lopez B, Perez C, Romero A, Del Barrio L, Martin-de-Saavedra MD, Egea J, Leon R and Rodriguez-Franco MI <4 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 46:2224, 2011 : PubMed

            

    Title: Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties
    Fernandez-Bachiller MI, Perez C, Gonzalez-Munoz GC, Conde S, Lopez MG, Villarroya M, Garcia AG, Rodriguez-Franco MI
    Ref: Journal of Medicinal Chemistry, 53:4927, 2010 : PubMed

            

    Title: Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases
    Gonzalez-Munoz GC, Arce MP, Lopez B, Perez C, Villarroya M, Lopez MG, Garcia AG, Conde S, Rodriguez-Franco MI
    Ref: Eur Journal of Medicinal Chemistry, 45:6152, 2010 : PubMed

            

    Title: Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease
    Arce MP, Rodriguez-Franco MI, Gonzalez-Munoz GC, Perez C, Lopez B, Villarroya M, Lopez MG, Garcia AG, Conde S
    Ref: Journal of Medicinal Chemistry, 52:7249, 2009 : PubMed

            

    Title: Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties
    Fernandez-Bachiller MI, Perez C, Campillo NE, Paez JA, Gonzalez-Munoz GC, Usan P, Garcia-Palomero E, Lopez MG, Villarroya M and Rodriguez-Franco MI <2 more author(s)>
    Ref: ChemMedChem, 4:828, 2009 : PubMed

            

    Title: Novel tacrine-melatonin hybrids as dual-acting drugs for Alzheimer disease, with improved acetylcholinesterase inhibitory and antioxidant properties
    Rodriguez-Franco MI, Fernandez-Bachiller MI, Perez C, Hernandez-Ledesma B, Bartolome B
    Ref: Journal of Medicinal Chemistry, 49:459, 2006 : PubMed

            

    Title: Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase
    Rodriguez-Franco MI, Fernandez-Bachiller MI, Perez C, Castro A, Martinez A
    Ref: Bioorganic & Medicinal Chemistry, 13:6795, 2005 : PubMed

            

    Title: Lipase-catalysed synthesis of new acetylcholinesterase inhibitors: N-benzylpiperidine aminoacid derivatives
    Martinez A, Lanot C, Perez C, Castro A, Lopez-Serrano P, Conde S
    Ref: Bioorganic & Medicinal Chemistry, 8:731, 2000 : PubMed

            

    Title: Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties
    Rodriguez-Franco MI, Dorronsoro I, Martinez A, Perez C, Badia A, Banos JE
    Ref: Arch Pharm (Weinheim), 333:118, 2000 : PubMed

            

    Title: bldA-dependent expression of the Streptomyces exfoliatus M11 lipase gene (lipA) is mediated by the product of a contiguous gene, lipR, encoding a putative transcriptional activator
    Servin-Gonzalez L, Castro C, Perez C, Rubio M, Valdez F
    Ref: Journal of Bacteriology, 179:7816, 1997 : PubMed

            

    Title: Sequence of the Streptomyces albus G lipase-encoding gene reveals the presence of a prokaryotic lipase family
    Cruz H, Perez C, Wellington E, Castro C, Servin-Gonzalez L
    Ref: Gene, 144:141, 1994 : PubMed

            

    Title: Cloning, characterization, and expression in Streptomyces lividans 66 of an extracellular lipase-encoding gene from Streptomyces sp. M11
    Perez C, Juarez K, Garcia-Castells E, Soberon G, Servin-Gonzalez L
    Ref: Gene, 123:109, 1993 : PubMed

            


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