Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
| Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008 |
| Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA |
| Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018 |
| Abstract : McAllister_2018_J.Med.Chem_61_3008 |
| ESTHER : McAllister_2018_J.Med.Chem_61_3008 |
| PubMedSearch : McAllister_2018_J.Med.Chem_61_3008 |
| PubMedID: 29498843 |
| Gene_locus related to this paper: human-MGLL |
| Title : Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase - Butler_2017_J.Med.Chem_60_9860 |
| Author(s) : Butler CR , Beck EM , Harris A , Huang Z , McAllister LA , Am Ende CW , Fennell K , Foley TL , Fonseca K , Hawrylik SJ , Johnson DS , Knafels JD , Mente S , Noell GS , Pandit J , Phillips TB , Piro JR , Rogers BN , Samad TA , Wang J , Wan S , Brodney MA |
| Ref : Journal of Medicinal Chemistry , 60 :9860 , 2017 |
| Abstract : Butler_2017_J.Med.Chem_60_9860 |
| ESTHER : Butler_2017_J.Med.Chem_60_9860 |
| PubMedSearch : Butler_2017_J.Med.Chem_60_9860 |
| PubMedID: 29148769 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism - Ahn_2016_ACS.Chem.Biol_11_2529 |
| Author(s) : Ahn K , Boehm M , Brown MF , Calloway J , Che Y , Chen J , Fennell KF , Geoghegan KF , Gilbert AM , Gutierrez JA , Kalgutkar AS , Lanba A , Limberakis C , Magee TV , O'Doherty I , Oliver R , Pabst B , Pandit J , Parris K , Pfefferkorn JA , Rolph TP , Patel R , Schuff B , Shanmugasundaram V , Starr JT , Varghese AH , Vera NB , Vernochet C , Yan J |
| Ref : ACS Chemical Biology , 11 :2529 , 2016 |
| Abstract : Ahn_2016_ACS.Chem.Biol_11_2529 |
| ESTHER : Ahn_2016_ACS.Chem.Biol_11_2529 |
| PubMedSearch : Ahn_2016_ACS.Chem.Biol_11_2529 |
| PubMedID: 27391855 |
| Gene_locus related to this paper: human-LYPLAL1 |
| Title : Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis - Pandit_2000_J.Biol.Chem_275_30610 |
| Author(s) : Pandit J , Danley DE , Schulte GK , Mazzalupo S , Pauly TA , Hayward CM , Hamanaka ES , Thompson JF , Harwood HJ |
| Ref : Journal of Biological Chemistry , 275 :30610 , 2000 |
| Abstract : Pandit_2000_J.Biol.Chem_275_30610 |
| ESTHER : Pandit_2000_J.Biol.Chem_275_30610 |
| PubMedSearch : Pandit_2000_J.Biol.Chem_275_30610 |
| PubMedID: 10896663 |