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| Title : A Sensitive and Versatile Fluorescent Activity Assay for ABHD6 - Savinainen_2016_Methods.Mol.Biol_1412_169 |
| Author(s) : Savinainen JR , Navia-Paldanius D , Laitinen JT |
| Ref : Methods Mol Biol , 1412 :169 , 2016 |
| Abstract : Savinainen_2016_Methods.Mol.Biol_1412_169 |
| ESTHER : Savinainen_2016_Methods.Mol.Biol_1412_169 |
| PubMedSearch : Savinainen_2016_Methods.Mol.Biol_1412_169 |
| PubMedID: 27245903 |
| Title : A Sensitive and Versatile Fluorescent Activity Assay for ABHD12 - Savinainen_2016_Methods.Mol.Biol_1412_179 |
| Author(s) : Savinainen JR , Navia-Paldanius D , Laitinen JT |
| Ref : Methods Mol Biol , 1412 :179 , 2016 |
| Abstract : Savinainen_2016_Methods.Mol.Biol_1412_179 |
| ESTHER : Savinainen_2016_Methods.Mol.Biol_1412_179 |
| PubMedSearch : Savinainen_2016_Methods.Mol.Biol_1412_179 |
| PubMedID: 27245904 |
| Title : Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha\/beta-hydrolase domain containing 11 (ABHD11) - Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 |
| Author(s) : Navia-Paldanius D , Patel JZ , Lopez Navarro M , Jakupovic H , Goffart S , Pasonen-Seppanen S , Nevalainen TJ , Jaaskelainen T , Laitinen T , Laitinen JT , Savinainen JR |
| Ref : Eur J Pharm Sci , 93 :253 , 2016 |
| Abstract : Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 |
| ESTHER : Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 |
| PubMedSearch : Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 |
| PubMedID: 27544863 |
| Gene_locus related to this paper: human-ABHD11 |
| Title : In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)m ethanone (JJKK-048) - Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| Author(s) : Aaltonen N , Kedzierska E , Orzelska-Gorka J , Lehtonen M , Navia-Paldanius D , Jakupovic H , Savinainen JR , Nevalainen T , Laitinen JT , Parkkari T , Gynther M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 359 :62 , 2016 |
| Abstract : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| ESTHER : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| PubMedSearch : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| PubMedID: 27451409 |
| Title : Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors - Patel_2015_ChemMedChem_10_253 |
| Author(s) : Patel JZ , Nevalainen TJ , Savinainen JR , Adams Y , Laitinen T , Runyon RS , Vaara M , Ahenkorah S , Kaczor AA , Navia-Paldanius D , Gynther M , Aaltonen N , Joharapurkar AA , Jain MR , Haka AS , Maxfield FR , Laitinen JT , Parkkari T |
| Ref : ChemMedChem , 10 :253 , 2015 |
| Abstract : Patel_2015_ChemMedChem_10_253 |
| ESTHER : Patel_2015_ChemMedChem_10_253 |
| PubMedSearch : Patel_2015_ChemMedChem_10_253 |
| PubMedID: 25504894 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi\/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase - Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| Author(s) : Navia-Paldanius D , Aaltonen N , Lehtonen M , Savinainen JR , Taschler U , Radner FP , Zimmermann R , Laitinen JT |
| Ref : Eur J Pharm Sci , 77 :180 , 2015 |
| Abstract : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| ESTHER : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| PubMedSearch : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| PubMedID: 26070239 |
| Title : Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors - Patel_2015_Bioorg.Med.Chem_23_6335 |
| Author(s) : Patel JZ , van Bruchem J , Laitinen T , Kaczor AA , Navia-Paldanius D , Parkkari T , Savinainen JR , Laitinen JT , Nevalainen TJ |
| Ref : Bioorganic & Medicinal Chemistry , 23 :6335 , 2015 |
| Abstract : Patel_2015_Bioorg.Med.Chem_23_6335 |
| ESTHER : Patel_2015_Bioorg.Med.Chem_23_6335 |
| PubMedSearch : Patel_2015_Bioorg.Med.Chem_23_6335 |
| PubMedID: 26344596 |
| Title : Loratadine analogues as MAGL inhibitors - Patel_2015_Bioorg.Med.Chem.Lett_25_1436 |
| Author(s) : Patel JZ , Ahenkorah S , Vaara M , Staszewski M , Adams Y , Laitinen T , Navia-Paldanius D , Parkkari T , Savinainen JR , Walczynski K , Laitinen JT , Nevalainen TJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 25 :1436 , 2015 |
| Abstract : Patel_2015_Bioorg.Med.Chem.Lett_25_1436 |
| ESTHER : Patel_2015_Bioorg.Med.Chem.Lett_25_1436 |
| PubMedSearch : Patel_2015_Bioorg.Med.Chem.Lett_25_1436 |
| PubMedID: 25752982 |
| Title : Discovery of Triterpenoids as Reversible Inhibitors of alpha\/beta-hydrolase Domain Containing 12 (ABHD12) - Parkkari_2014_PLoS.One_9_e98286 |
| Author(s) : Parkkari T , Haavikko R , Laitinen T , Navia-Paldanius D , Rytilahti R , Vaara M , Lehtonen M , Alakurtti S , Yli-Kauhaluoma J , Nevalainen T , Savinainen JR , Laitinen JT |
| Ref : PLoS ONE , 9 :e98286 , 2014 |
| Abstract : Parkkari_2014_PLoS.One_9_e98286 |
| ESTHER : Parkkari_2014_PLoS.One_9_e98286 |
| PubMedSearch : Parkkari_2014_PLoS.One_9_e98286 |
| PubMedID: 24879289 |
| Gene_locus related to this paper: human-ABHD12 |
| Title : Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5\/ABHD16A) - Savinainen_2014_PLoS.One_9_e109869 |
| Author(s) : Savinainen JR , Patel JZ , Parkkari T , Navia-Paldanius D , Marjamaa JJ , Laitinen T , Nevalainen T , Laitinen JT |
| Ref : PLoS ONE , 9 :e109869 , 2014 |
| Abstract : Savinainen_2014_PLoS.One_9_e109869 |
| ESTHER : Savinainen_2014_PLoS.One_9_e109869 |
| PubMedSearch : Savinainen_2014_PLoS.One_9_e109869 |
| PubMedID: 25290914 |
| Gene_locus related to this paper: human-ABHD16A , mouse-Abhd16a |
| Title : Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL) - Savinainen_2014_Mol.Pharmacol_86_522 |
| Author(s) : Savinainen JR , Kansanen E , Pantsar T , Navia-Paldanius D , Parkkari T , Lehtonen M , Laitinen T , Nevalainen T , Poso A , Levonen AL , Laitinen JT |
| Ref : Molecular Pharmacology , 86 :522 , 2014 |
| Abstract : Savinainen_2014_Mol.Pharmacol_86_522 |
| ESTHER : Savinainen_2014_Mol.Pharmacol_86_522 |
| PubMedSearch : Savinainen_2014_Mol.Pharmacol_86_522 |
| PubMedID: 25140003 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency - Laitinen_2014_Mol.Pharmacol_85_510 |
| Author(s) : Laitinen T , Navia-Paldanius D , Rytilahti R , Marjamaa JJ , Karizkova J , Parkkari T , Pantsar T , Poso A , Laitinen JT , Savinainen JR |
| Ref : Molecular Pharmacology , 85 :510 , 2014 |
| Abstract : Laitinen_2014_Mol.Pharmacol_85_510 |
| ESTHER : Laitinen_2014_Mol.Pharmacol_85_510 |
| PubMedSearch : Laitinen_2014_Mol.Pharmacol_85_510 |
| PubMedID: 24368842 |
| Gene_locus related to this paper: human-MGLL |
| Title : Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) - Korhonen_2014_Bioorg.Med.Chem_22_6694 |
| Author(s) : Korhonen J , Kuusisto A , van Bruchem J , Patel JZ , Laitinen T , Navia-Paldanius D , Laitinen JT , Savinainen JR , Parkkari T , Nevalainen TJ |
| Ref : Bioorganic & Medicinal Chemistry , 22 :6694 , 2014 |
| Abstract : Korhonen_2014_Bioorg.Med.Chem_22_6694 |
| ESTHER : Korhonen_2014_Bioorg.Med.Chem_22_6694 |
| PubMedSearch : Korhonen_2014_Bioorg.Med.Chem_22_6694 |
| PubMedID: 25282655 |
| Title : Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase - Aaltonen_2013_Chem.Biol_20_379 |
| Author(s) : Aaltonen N , Savinainen JR , Ribas CR , Ronkko J , Kuusisto A , Korhonen J , Navia-Paldanius D , Hayrinen J , Takabe P , Kasnanen H , Pantsar T , Laitinen T , Lehtonen M , Pasonen-Seppanen S , Poso A , Nevalainen T , Laitinen JT |
| Ref : Chemical Biology , 20 :379 , 2013 |
| Abstract : Aaltonen_2013_Chem.Biol_20_379 |
| ESTHER : Aaltonen_2013_Chem.Biol_20_379 |
| PubMedSearch : Aaltonen_2013_Chem.Biol_20_379 |
| PubMedID: 23521796 |
| Gene_locus related to this paper: human-MGLL |
| Title : Biochemical and pharmacological characterization of human alpha\/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12) - Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| Author(s) : Navia-Paldanius D , Savinainen JR , Laitinen JT |
| Ref : J Lipid Res , 53 :2413 , 2012 |
| Abstract : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| ESTHER : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| PubMedSearch : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| PubMedID: 22969151 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 |