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| Title : Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]py ridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778) - Devasthale_2013_J.Med.Chem_56_7343 |
| Author(s) : Devasthale P , Wang Y , Wang W , Fevig J , Feng J , Wang A , Harrity T , Egan D , Morgan N , Cap M , Fura A , Klei HE , Kish K , Weigelt C , Sun L , Levesque P , Moulin F , Li YX , Zahler R , Kirby MS , Hamann LG |
| Ref : Journal of Medicinal Chemistry , 56 :7343 , 2013 |
| Abstract : Devasthale_2013_J.Med.Chem_56_7343 |
| ESTHER : Devasthale_2013_J.Med.Chem_56_7343 |
| PubMedSearch : Devasthale_2013_J.Med.Chem_56_7343 |
| PubMedID: 23964740 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Presence or absence of at least one epsilon 4 allele and gender are not predictive for the response to donepezil treatment in Alzheimer's disease - Rigaud_2002_Pharmacogenet_12_415 |
| Author(s) : Rigaud AS , Traykov L , Latour F , Couderc R , Moulin F , Forette F |
| Ref : Pharmacogenetics , 12 :415 , 2002 |
| Abstract : Rigaud_2002_Pharmacogenet_12_415 |
| ESTHER : Rigaud_2002_Pharmacogenet_12_415 |
| PubMedSearch : Rigaud_2002_Pharmacogenet_12_415 |
| PubMedID: 12142731 |
| Title : The apolipoprotein E epsilon4 allele and the response to tacrine therapy in Alzheimer's disease - Rigaud_2000_Clin.Chem.Lab.Med_38_205 |
| Author(s) : Rigaud AS , Traykov L , Caputo L , Guelfi MC , Latour F , Couderc R , Moulin F , de Rotrou J , Forette F , Boller F |
| Ref : Clinical Chemistry & Laboratory Medicine , 38 :205 , 2000 |
| Abstract : Rigaud_2000_Clin.Chem.Lab.Med_38_205 |
| ESTHER : Rigaud_2000_Clin.Chem.Lab.Med_38_205 |
| PubMedSearch : Rigaud_2000_Clin.Chem.Lab.Med_38_205 |
| PubMedID: 10886308 |