Full name : Moreland David W
First name : David W
Mail : Pfizer Global Research and Development, Ann Arbor, MI
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Country : USA
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| Title : Poster: Benzoxazine isoquinolines as M4 selective muscarinic receptor antagonists - |
| Author(s) : Schwarz RD , Bohme TM , Augelli-Szafran CE , Moreland DW |
| Ref : Life Sciences , 68 :2626 , 2001 |
| PubMedID: |
| Title : CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology - Tecle_2000_Pharm.Acta.Helv_74_141 |
| Author(s) : Tecle H , Schwarz RD , Barrett SD , Callahan MJ , Caprathe BW , Davis RE , Doyle P , Emmerling M , Lauffer DJ , Mirzadegan T , Moreland DW , Lipiniski W , Nelson C , Raby C , Spencer C , Spiegel K , Thomas AJ , Jaen JC |
| Ref : Pharm Acta Helv , 74 :141 , 2000 |
| Abstract : Tecle_2000_Pharm.Acta.Helv_74_141 |
| ESTHER : Tecle_2000_Pharm.Acta.Helv_74_141 |
| PubMedSearch : Tecle_2000_Pharm.Acta.Helv_74_141 |
| PubMedID: 10812951 |
| Title : Identification and characterization of m1 selective muscarinic receptor antagonists1 - Augelli-Szafran_1999_J.Med.Chem_42_356 |
| Author(s) : Augelli-Szafran CE , Blankley CJ , Jaen JC , Moreland DW , Nelson CB , Penvose-Yi JR , Schwarz RD , Thomas AJ |
| Ref : Journal of Medicinal Chemistry , 42 :356 , 1999 |
| Abstract : Augelli-Szafran_1999_J.Med.Chem_42_356 |
| ESTHER : Augelli-Szafran_1999_J.Med.Chem_42_356 |
| PubMedSearch : Augelli-Szafran_1999_J.Med.Chem_42_356 |
| PubMedID: 9986705 |
| Title : Identification and characterization of m4 selective muscarinic antagonists - Augelli-Szafran_1998_Bioorg.Med.Chem.Lett_8_1991 |
| Author(s) : Augelli-Szafran CE , Jaen JC , Moreland DW , Nelson CB , Penvose-Yi JR , Schwarz RD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :1991 , 1998 |
| Abstract : Augelli-Szafran_1998_Bioorg.Med.Chem.Lett_8_1991 |
| ESTHER : Augelli-Szafran_1998_Bioorg.Med.Chem.Lett_8_1991 |
| PubMedSearch : Augelli-Szafran_1998_Bioorg.Med.Chem.Lett_8_1991 |
| PubMedID: 9873472 |
| Title : Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist - Tecle_1998_J.Med.Chem_41_2524 |
| Author(s) : Tecle H , Barrett SD , Lauffer DJ , Augelli-Szafran C , Brann MR , Callahan MJ , Caprathe BW , Davis RE , Doyle PD , Eubanks D , Lipiniski W , Mirzadegan T , Moos WH , Moreland DW , Nelson CB , Pavia MR , Raby C , Schwarz RD , Spencer CJ , Thomas AJ , Jaen JC |
| Ref : Journal of Medicinal Chemistry , 41 :2524 , 1998 |
| Abstract : Tecle_1998_J.Med.Chem_41_2524 |
| ESTHER : Tecle_1998_J.Med.Chem_41_2524 |
| PubMedSearch : Tecle_1998_J.Med.Chem_41_2524 |
| PubMedID: 9651157 |
| Title : Poster: Identification and characterization of m4 selective muscarinic antagonists - |
| Author(s) : Augelli-Szafran CE , Moreland DW , Nelson CB , Penvose-Yi JR , Schwarz RD , Jaen JC |
| Ref : Life Sciences , 60 :1168 , 1997 |
| PubMedID: |
| Title : In vitro and in vivo evaluation of the subtype-selective muscarinic agonist PD 151832 - Jaen_1995_Life.Sci_56(11-12)_845 |
| Author(s) : Jaen JC , Barrett S , Brann M , Callahan M , Davis R , Doyle P , Eubanks D , Lauffer DJ , Lauffer L , Lipinski W , Moreland DW , Nelson C , Raby C , Schwarz RD , Spencer CJ , Tecle H |
| Ref : Life Sciences , 56(11-12) :845 , 1995 |
| Abstract : Jaen_1995_Life.Sci_56(11-12)_845 |
| ESTHER : Jaen_1995_Life.Sci_56(11-12)_845 |
| PubMedSearch : Jaen_1995_Life.Sci_56(11-12)_845 |
| PubMedID: 10188784 |
| Title : Mutations of aspartate 103 in the Hm2 receptor and alterations in receptor binding properties of muscarinic agonists - Schwarz_1995_Life.Sci_56(11-12)_923 |
| Author(s) : Schwarz RD , Spencer CJ , Jaen JC , Mirzadegan T , Moreland DW , Tecle H , Thomas AJ |
| Ref : Life Sciences , 56(11-12) :923 , 1995 |
| Abstract : Schwarz_1995_Life.Sci_56(11-12)_923 |
| ESTHER : Schwarz_1995_Life.Sci_56(11-12)_923 |
| PubMedSearch : Schwarz_1995_Life.Sci_56(11-12)_923 |
| PubMedID: 10188794 |
| Title : Poster: Aryleneyne 1-azabicyclo[2.2.1]heptan-3-one oximes: Potent muscarinic agonists - |
| Author(s) : Tecle H , Lauffer DJ , Davis RE , Mirzadegan T , Moreland DW , Schwarz RD , Thomas AJ , Raby C , Jaen JC |
| Ref : Life Sciences , 56(11-12) :1003 , 1995 |
| PubMedID: |
| Title : Poster: Identification and characterization of m1 selective muscarinic antagonists - |
| Author(s) : Augelli-Szafran CE , Blankley CJ , Jaen JC , Moreland DW , Nelson CB , Penvose JR , Schwarz RD , Thomas AJ |
| Ref : Life Sciences , 56(11-12) :1017 , 1995 |
| PubMedID: |
| Title : Poster: Effect of mutating aspart ate 103 to glutamate or asparagine in the Hm2 subtype on binding of agonists and antagonists of varied pKa and subtype selectivity - |
| Author(s) : Spencer CJ , Schwarz RD , Moreland DW , Thomas AJ , Tecle H |
| Ref : Life Sciences , 56(11-12) :1020 , 1995 |
| PubMedID: |
| Title : Synthesis and SAR of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists - Tecle_1993_Life.Sci_52(5-6)_505 |
| Author(s) : Tecle H , Lauffer DJ , Mirzadegan T , Moos WH , Moreland DW , Pavia MR , Schwarz RD , Davis RE |
| Ref : Life Sciences , 52 :505 , 1993 |
| Abstract : Tecle_1993_Life.Sci_52(5-6)_505 |
| ESTHER : Tecle_1993_Life.Sci_52(5-6)_505 |
| PubMedSearch : Tecle_1993_Life.Sci_52(5-6)_505 |
| PubMedID: 8382765 |
| Title : Poster: A model for ligand binding at the muscarinic cholinergic receptor - |
| Author(s) : Moreland DW |
| Ref : Life Sciences , 52(5-6) :559 , 1993 |
| PubMedID: |