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| Title : 1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists - Ward_1998_J.Med.Chem_41_379 |
| Author(s) : Ward JS , Merritt L , Calligaro DO , Bymaster FP , Shannon HE , Mitch CH , Whitesitt CA , Brunsting D , Sheardown MJ , Olesen PH , Swedberg MD , Jeppesen L , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 41 :379 , 1998 |
| Abstract : Ward_1998_J.Med.Chem_41_379 |
| ESTHER : Ward_1998_J.Med.Chem_41_379 |
| PubMedSearch : Ward_1998_J.Med.Chem_41_379 |
| PubMedID: 9464368 |
| Title : Poster: The tetrahydropyridine ring confers optimal M-1 selectivity and blood brain barrier penetration among hexyloxy-1,2,5-thiadiazole azacycles - |
| Author(s) : Ward JS , Merritt L , Stratford R , Brown TJ , Wijayaratne R , Szewczyk SP , Calligaro DO , Bymaster FP , Shannon HE , Mitch CH , Johnson DW , Wikel JH , Olesen PH , Sheardown MJ , Swedberg MD , Sauerberg P |
| Ref : Life Sciences , 60 :1165 , 1997 |
| PubMedID: |
| Title : Poster: 3-(3-Hexyloxypyrazinyl)quinuclidine as a functionally selective M1 agonist - |
| Author(s) : Ward JS , Merritt L , Calligaro DO , Bymaster FP , Shannon HE , Sawyer BD , Mitch CH , Sheardown MJ , Olesen PH , Suzdak PD , Swedberg MD , Sauerberg P |
| Ref : Life Sciences , 56(11-12) :1003 , 1995 |
| PubMedID: |
| Title : Functionally selective M1 muscarinic agonists. 3. Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles - Ward_1995_J.Med.Chem_38_3469 |
| Author(s) : Ward JS , Merritt L , Calligaro DO , Bymaster FP , Shannon HE , Sawyer BD , Mitch CH , Deeter JB , Peters SC , Sheardown MJ , Olesen PH , Swedberg MD , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 38 :3469 , 1995 |
| Abstract : Ward_1995_J.Med.Chem_38_3469 |
| ESTHER : Ward_1995_J.Med.Chem_38_3469 |
| PubMedSearch : Ward_1995_J.Med.Chem_38_3469 |
| PubMedID: 7658434 |
| Title : Poster: Synthesis and structure-activity relationship of 3-(pyrazinyl)- 1, 2, 5, 6-tetrahydro-1-methylpyridines. Construction of a molecular model for the M-1 pharmacophore - |
| Author(s) : Ward JS , Merritt L , Klimkowski VJ , Lamb ML , Mitch CH , Bymaster FP , Sawyer BD , Shannon HE , Olesen PH , Honore T , Sheardown MJ , Sauerberg P |
| Ref : Life Sciences , 52(5-6) :549 , 1993 |
| PubMedID: |
| Title : Poster: Electronic requirements in a series of arecoline derivatives for muscarinic receptor-stimulated phosphoinositide metabolism in the rat brain - |
| Author(s) : Hoss WP , Ngur DO , Roknich S , Mitch CH , Quimby SJ , Ward JS , Merritt L , Sauerberg P , Messer WS, Jr. |
| Ref : Life Sciences , 52(5-6) :552 , 1993 |
| PubMedID: |
| Title : Novel functional M1 selective muscarinic agonists. 2. Synthesis and structure-activity relationships of 3-pyrazinyl-1,2,5,6-tetrahydro-1-methylpyridines. Construction of a molecular model for the M1 pharmacophore - Ward_1992_J.Med.Chem_35_4011 |
| Author(s) : Ward JS , Merritt L , Klimkowski VJ , Lamb ML , Mitch CH , Bymaster FP , Sawyer BD , Shannon HE , Olesen PH , Honore T , Sheardown MJ , Sauerberg P |
| Ref : Journal of Medicinal Chemistry , 35 :4011 , 1992 |
| Abstract : Ward_1992_J.Med.Chem_35_4011 |
| ESTHER : Ward_1992_J.Med.Chem_35_4011 |
| PubMedSearch : Ward_1992_J.Med.Chem_35_4011 |
| PubMedID: 1433209 |
| Title : Steric and electronic requirements for muscarinic receptor-stimulated phosphoinositide turnover in the CNS in a series of arecoline bioisosteres - Ngur_1992_Biochem.Biophys.Res.Commun_187_1389 |
| Author(s) : Ngur D , Roknich S , Mitch CH , Quimby SJ , Ward JS , Merritt L , Sauerberg P , Messer WS, Jr. , Hoss WP |
| Ref : Biochemical & Biophysical Research Communications , 187 :1389 , 1992 |
| Abstract : Ngur_1992_Biochem.Biophys.Res.Commun_187_1389 |
| ESTHER : Ngur_1992_Biochem.Biophys.Res.Commun_187_1389 |
| PubMedSearch : Ngur_1992_Biochem.Biophys.Res.Commun_187_1389 |
| PubMedID: 1329735 |