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| Title : Atherosclerotic plaque inflammation varies between vascular sites and correlates with response to inhibition of lipoprotein-associated phospholipase A2 - Fenning_2015_J.Am.Heart.Assoc_4_ |
| Author(s) : Fenning RS , Burgert ME , Hamamdzic D , Peyster EG , Mohler ER , Kangovi S , Jucker BM , Lenhard SC , Macphee CH , Wilensky RL |
| Ref : J Am Heart Assoc , 4 : , 2015 |
| Abstract : Fenning_2015_J.Am.Heart.Assoc_4_ |
| ESTHER : Fenning_2015_J.Am.Heart.Assoc_4_ |
| PubMedSearch : Fenning_2015_J.Am.Heart.Assoc_4_ |
| PubMedID: 25672369 |
| Title : Platelet aggregation unchanged by lipoprotein-associated phospholipase A inhibition: results from an in vitro study and two randomized phase I trials - Shaddinger_2014_PLoS.One_9_e83094 |
| Author(s) : Shaddinger BC , Xu Y , Roger JH , Macphee CH , Handel M , Baidoo CA , Magee M , Lepore JJ , Sprecher DL |
| Ref : PLoS ONE , 9 :e83094 , 2014 |
| Abstract : Shaddinger_2014_PLoS.One_9_e83094 |
| ESTHER : Shaddinger_2014_PLoS.One_9_e83094 |
| PubMedSearch : Shaddinger_2014_PLoS.One_9_e83094 |
| PubMedID: 24475026 |
| Title : Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial - Johnson_2014_PLoS.One_9_e89034 |
| Author(s) : Johnson JL , Shi Y , Snipes R , Janmohamed S , Rolfe TE , Davis B , Postle A , Macphee CH |
| Ref : PLoS ONE , 9 :e89034 , 2014 |
| Abstract : Johnson_2014_PLoS.One_9_e89034 |
| ESTHER : Johnson_2014_PLoS.One_9_e89034 |
| PubMedSearch : Johnson_2014_PLoS.One_9_e89034 |
| PubMedID: 24586490 |
| Title : Lipoprotein-associated phospholipase A(2) and atherosclerosis - Wilensky_2009_Curr.Opin.Lipidol_20_415 |
| Author(s) : Wilensky RL , Macphee CH |
| Ref : Curr Opin Lipidol , 20 :415 , 2009 |
| Abstract : Wilensky_2009_Curr.Opin.Lipidol_20_415 |
| ESTHER : Wilensky_2009_Curr.Opin.Lipidol_20_415 |
| PubMedSearch : Wilensky_2009_Curr.Opin.Lipidol_20_415 |
| PubMedID: 19667981 |
| Title : Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development - Wilensky_2008_Nat.Med_14_1059 |
| Author(s) : Wilensky RL , Shi Y , Mohler ER, 3rd , Hamamdzic D , Burgert ME , Li J , Postle A , Fenning RS , Bollinger JG , Hoffman BE , Pelchovitz DJ , Yang J , Mirabile RC , Webb CL , Zhang L , Zhang P , Gelb MH , Walker MC , Zalewski A , Macphee CH |
| Ref : Nat Med , 14 :1059 , 2008 |
| Abstract : Wilensky_2008_Nat.Med_14_1059 |
| ESTHER : Wilensky_2008_Nat.Med_14_1059 |
| PubMedSearch : Wilensky_2008_Nat.Med_14_1059 |
| PubMedID: 18806801 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2 - Blackie_2003_Bioorg.Med.Chem.Lett_13_1067 |
| Author(s) : Blackie JA , Bloomer JC , Brown MJ , Cheng HY , Hammond B , Hickey DM , Ife RJ , Leach CA , Lewis VA , Macphee CH , Milliner KJ , Moores KE , Pinto IL , Smith SA , Stansfield IG , Stanway SJ , Taylor MA , Theobald CJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 13 :1067 , 2003 |
| Abstract : Blackie_2003_Bioorg.Med.Chem.Lett_13_1067 |
| ESTHER : Blackie_2003_Bioorg.Med.Chem.Lett_13_1067 |
| PubMedSearch : Blackie_2003_Bioorg.Med.Chem.Lett_13_1067 |
| PubMedID: 12643913 |
| Title : The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2 - Boyd_2001_Bioorg.Med.Chem.Lett_11_701 |
| Author(s) : Boyd HF , Hammond B , Hickey DM , Ife RJ , Leach CA , Lewis VA , Macphee CH , Milliner KJ , Pinto IL , Smith SA , Stansfield IG , Theobald CJ , Whittaker CM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 11 :701 , 2001 |
| Abstract : Boyd_2001_Bioorg.Med.Chem.Lett_11_701 |
| ESTHER : Boyd_2001_Bioorg.Med.Chem.Lett_11_701 |
| PubMedSearch : Boyd_2001_Bioorg.Med.Chem.Lett_11_701 |
| PubMedID: 11266173 |
| Title : Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group - Packard_2000_N.Engl.J.Med_343_1148 |
| Author(s) : Packard CJ , O'Reilly DS , Caslake MJ , McMahon AD , Ford I , Cooney J , Macphee CH , Suckling KE , Krishna M , Wilkinson FE , Rumley A , Lowe GD |
| Ref : N Engl J Med , 343 :1148 , 2000 |
| Abstract : Packard_2000_N.Engl.J.Med_343_1148 |
| ESTHER : Packard_2000_N.Engl.J.Med_343_1148 |
| PubMedSearch : Packard_2000_N.Engl.J.Med_343_1148 |
| PubMedID: 11036120 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : 2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2 - Boyd_2000_Bioorg.Med.Chem.Lett_10_395 |
| Author(s) : Boyd HF , Flynn ST , Hickey DM , Ife RJ , Jones M , Leach CA , Macphee CH , Milliner KJ , Rawlings DA , Slingsby BP , Smith SA , Stansfield IG , Tew DG , Theobald CJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 10 :395 , 2000 |
| Abstract : Boyd_2000_Bioorg.Med.Chem.Lett_10_395 |
| ESTHER : Boyd_2000_Bioorg.Med.Chem.Lett_10_395 |
| PubMedSearch : Boyd_2000_Bioorg.Med.Chem.Lett_10_395 |
| PubMedID: 10714508 |
| Title : Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor - MacPhee_1999_Biochem.J_338 ( Pt 2)_479 |
| Author(s) : Macphee CH , Moores KE , Boyd HF , Dhanak D , Ife RJ , Leach CA , Leake DS , Milliner KJ , Patterson RA , Suckling KE , Tew DG , Hickey DM |
| Ref : Biochemical Journal , 338 ( Pt 2) :479 , 1999 |
| Abstract : MacPhee_1999_Biochem.J_338 ( Pt 2)_479 |
| ESTHER : MacPhee_1999_Biochem.J_338 ( Pt 2)_479 |
| PubMedSearch : MacPhee_1999_Biochem.J_338 ( Pt 2)_479 |
| PubMedID: 10024526 |
| Title : Expression, purification and characterization of a human serine-dependent phospholipase A2 with high specificity for oxidized phospholipids and platelet activating factor - Rice_1998_Biochem.J_330 ( Pt 3)_1309 |
| Author(s) : Rice SQ , Southan C , Boyd HF , Terrett JA , Macphee CH , Moores K , Gloger IS , Tew DG |
| Ref : Biochemical Journal , 330 ( Pt 3) :1309 , 1998 |
| Abstract : Rice_1998_Biochem.J_330 ( Pt 3)_1309 |
| ESTHER : Rice_1998_Biochem.J_330 ( Pt 3)_1309 |
| PubMedSearch : Rice_1998_Biochem.J_330 ( Pt 3)_1309 |
| PubMedID: 9494101 |
| Gene_locus related to this paper: human-PAFAH2 |
| Title : Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia - Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| Author(s) : Bell R , Collier DA , Rice SQ , Roberts GW , Macphee CH , Kerwin RW , Price J , Gloger IS |
| Ref : Biochemical & Biophysical Research Communications , 241 :630 , 1997 |
| Abstract : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| ESTHER : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| PubMedSearch : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| PubMedID: 9434759 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins - Tew_1996_Arterioscler.Thromb.Vasc.Biol_16_591 |
| Author(s) : Tew DG , Southan C , Rice SQ , Lawrence MP , Li H , Boyd HF , Moores K , Gloger IS , Macphee CH |
| Ref : Arterioscler Thromb Vasc Biol , 16 :591 , 1996 |
| Abstract : Tew_1996_Arterioscler.Thromb.Vasc.Biol_16_591 |
| ESTHER : Tew_1996_Arterioscler.Thromb.Vasc.Biol_16_591 |
| PubMedSearch : Tew_1996_Arterioscler.Thromb.Vasc.Biol_16_591 |
| PubMedID: 8624782 |
| Gene_locus related to this paper: human-PLA2G7 |