Report for Lester HA

General

Full name : Lester Henry A

First name : Henry A

Mail : California Institute of Technology, Division of Biology, Pasadena, California 91125

Zip Code :

City :

Country : USA

Email : lester@caltech.edu

Phone :

Fax :

Website : \/\/www.bbe.caltech.edu\/content\/henry-lester

Directory :

References (165)

Title : Protein profiling in the habenula after chronic (-)-menthol exposure in mice - Mulcahy_2021_J.Neurochem__
Author(s) : Mulcahy MJ , Huard SM , Paulo JA , Wang JH , McKinney S , Marks MJ , Henderson BJ , Lester HA
Ref : Journal of Neurochemistry , : , 2021
Abstract : Mulcahy_2021_J.Neurochem__
ESTHER : Mulcahy_2021_J.Neurochem__
PubMedSearch : Mulcahy_2021_J.Neurochem__
PubMedID: 34407206

Title : Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type alpha-synuclein - Subramaniam_2018_Neurobiol.Dis_117_170
Author(s) : Subramaniam SR , Magen I , Bove N , Zhu C , Lemesre V , Dutta G , Elias CJ , Lester HA , Chesselet MF
Ref : Neurobiol Dis , 117 :170 , 2018
Abstract : Subramaniam_2018_Neurobiol.Dis_117_170
ESTHER : Subramaniam_2018_Neurobiol.Dis_117_170
PubMedSearch : Subramaniam_2018_Neurobiol.Dis_117_170
PubMedID: 29859873

Title : Granulocytes as models for human protein marker identification following nicotine exposure - Mulcahy_2017_J.Neurochem_142 Suppl 2_151
Author(s) : Mulcahy MJ , Lester HA
Ref : Journal of Neurochemistry , 142 Suppl 2 :151 , 2017
Abstract : Mulcahy_2017_J.Neurochem_142 Suppl 2_151
ESTHER : Mulcahy_2017_J.Neurochem_142 Suppl 2_151
PubMedSearch : Mulcahy_2017_J.Neurochem_142 Suppl 2_151
PubMedID: 28791704

Title : Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity alpha4beta2, and Increases alpha5alpha4beta2, Nicotinic Receptor Surface Expression - Nichols_2016_PLoS.One_11_e0158032
Author(s) : Nichols WA , Henderson BJ , Marotta CB , Yu CY , Richards C , Dougherty DA , Lester HA , Cohen BN
Ref : PLoS ONE , 11 :e0158032 , 2016
Abstract : Nichols_2016_PLoS.One_11_e0158032
ESTHER : Nichols_2016_PLoS.One_11_e0158032
PubMedSearch : Nichols_2016_PLoS.One_11_e0158032
PubMedID: 27336596

Title : Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons - Srinivasan_2016_J.Neurosci_36_65
Author(s) : Srinivasan R , Henley BM , Henderson BJ , Indersmitten T , Cohen BN , Kim CH , McKinney S , Deshpande P , Xiao C , Lester HA
Ref : Journal of Neuroscience , 36 :65 , 2016
Abstract : Srinivasan_2016_J.Neurosci_36_65
ESTHER : Srinivasan_2016_J.Neurosci_36_65
PubMedSearch : Srinivasan_2016_J.Neurosci_36_65
PubMedID: 26740650

Title : Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward - Henderson_2016_J.Neurosci_36_2957
Author(s) : Henderson BJ , Wall TR , Henley BM , Kim CH , Nichols WA , Moaddel R , Xiao C , Lester HA
Ref : Journal of Neuroscience , 36 :2957 , 2016
Abstract : Henderson_2016_J.Neurosci_36_2957
ESTHER : Henderson_2016_J.Neurosci_36_2957
PubMedSearch : Henderson_2016_J.Neurosci_36_2957
PubMedID: 26961950

Title : An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in alpha7 Nicotinic Acetylcholine Receptors - Marotta_2015_Chem.Biol_22_1063
Author(s) : Marotta CB , Lester HA , Dougherty DA
Ref : Chemical Biology , 22 :1063 , 2015
Abstract : Marotta_2015_Chem.Biol_22_1063
ESTHER : Marotta_2015_Chem.Biol_22_1063
PubMedSearch : Marotta_2015_Chem.Biol_22_1063
PubMedID: 26211363

Title : Heterologous expression and nonsense suppression provide insights into agonist behavior at alpha6beta2 nicotinic acetylcholine receptors - Post_2015_Neuropharmacol_97_376
Author(s) : Post MR , Limapichat W , Lester HA , Dougherty DA
Ref : Neuropharmacology , 97 :376 , 2015
Abstract : Post_2015_Neuropharmacol_97_376
ESTHER : Post_2015_Neuropharmacol_97_376
PubMedSearch : Post_2015_Neuropharmacol_97_376
PubMedID: 25908401

Title : The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function - Sinkus_2015_Neuropharmacol_96_274
Author(s) : Sinkus ML , Graw S , Freedman R , Ross RG , Lester HA , Leonard S
Ref : Neuropharmacology , 96 :274 , 2015
Abstract : Sinkus_2015_Neuropharmacol_96_274
ESTHER : Sinkus_2015_Neuropharmacol_96_274
PubMedSearch : Sinkus_2015_Neuropharmacol_96_274
PubMedID: 25701707

Title : The nicotinic alpha6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2\/3 receptors - Wieskopf_2015_Sci.Transl.Med_7_287ra72
Author(s) : Wieskopf JS , Mathur J , Limapichat W , Post MR , Al-Qazzaz M , Sorge RE , Martin LJ , Zaykin DV , Smith SB , Freitas K , Austin JS , Dai F , Zhang J , Marcovitz J , Tuttle AH , Slepian PM , Clarke S , Drenan RM , Janes J , Al Sharari S , Segall SK , Aasvang EK , Lai W , Bittner R , Richards CI , Slade GD , Kehlet H , Walker J , Maskos U , Changeux JP , Devor M , Maixner W , Diatchenko L , Belfer I , Dougherty DA , Su AI , Lummis SC , Damaj MI , Lester HA , Patapoutian A , Mogil JS
Ref : Sci Transl Med , 7 :287ra72 , 2015
Abstract : Wieskopf_2015_Sci.Transl.Med_7_287ra72
ESTHER : Wieskopf_2015_Sci.Transl.Med_7_287ra72
PubMedSearch : Wieskopf_2015_Sci.Transl.Med_7_287ra72
PubMedID: 25972004

Title : Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus - Xiao_2015_J.Neurosci_35_3734
Author(s) : Xiao C , Miwa JM , Henderson BJ , Wang Y , Deshpande P , McKinney SL , Lester HA
Ref : Journal of Neuroscience , 35 :3734 , 2015
Abstract : Xiao_2015_J.Neurosci_35_3734
ESTHER : Xiao_2015_J.Neurosci_35_3734
PubMedSearch : Xiao_2015_J.Neurosci_35_3734
PubMedID: 25740504

Title : Inside-out neuropharmacology of nicotinic drugs - Henderson_2015_Neuropharmacol_96_178
Author(s) : Henderson BJ , Lester HA
Ref : Neuropharmacology , 96 :178 , 2015
Abstract : Henderson_2015_Neuropharmacol_96_178
ESTHER : Henderson_2015_Neuropharmacol_96_178
PubMedSearch : Henderson_2015_Neuropharmacol_96_178
PubMedID: 25660637

Title : Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors - Henderson_2014_J.Gen.Physiol_143_51
Author(s) : Henderson BJ , Srinivasan R , Nichols WA , Dilworth CN , Gutierrez DF , Mackey ED , McKinney S , Drenan RM , Richards CI , Lester HA
Ref : Journal of General Physiology , 143 :51 , 2014
Abstract : Henderson_2014_J.Gen.Physiol_143_51
ESTHER : Henderson_2014_J.Gen.Physiol_143_51
PubMedSearch : Henderson_2014_J.Gen.Physiol_143_51
PubMedID: 24378908

Title : The duplicated alpha7 subunits assemble and form functional nicotinic receptors with the full-length alpha7 - Wang_2014_J.Biol.Chem_289_26451
Author(s) : Wang Y , Xiao C , Indersmitten T , Freedman R , Leonard S , Lester HA
Ref : Journal of Biological Chemistry , 289 :26451 , 2014
Abstract : Wang_2014_J.Biol.Chem_289_26451
ESTHER : Wang_2014_J.Biol.Chem_289_26451
PubMedSearch : Wang_2014_J.Biol.Chem_289_26451
PubMedID: 25056953

Title : Lynx1 Shifts alpha4beta2 Nicotinic Receptor Subunit Stoichiometry by Affecting Assembly in the Endoplasmic Reticulum - Nichols_2014_J.Biol.Chem_289_31423
Author(s) : Nichols WA , Henderson BJ , Yu C , Parker RL , Richards CI , Lester HA , Miwa JM
Ref : Journal of Biological Chemistry , 289 :31423 , 2014
Abstract : Nichols_2014_J.Biol.Chem_289_31423
ESTHER : Nichols_2014_J.Biol.Chem_289_31423
PubMedSearch : Nichols_2014_J.Biol.Chem_289_31423
PubMedID: 25193667

Title : lynx1 Supports Neuronal Health in the Mouse Dorsal Striatum During Aging: an Ultrastructural Investigation - Kobayashi_2014_J.Mol.Neurosci_53_525
Author(s) : Kobayashi A , Parker RL , Wright AP , Brahem H , Ku P , Oliver KM , Walz A , Lester HA , Miwa JM
Ref : Journal of Molecular Neuroscience , 53 :525 , 2014
Abstract : Kobayashi_2014_J.Mol.Neurosci_53_525
ESTHER : Kobayashi_2014_J.Mol.Neurosci_53_525
PubMedSearch : Kobayashi_2014_J.Mol.Neurosci_53_525
PubMedID: 25027556

Title : Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease - Srinivasan_2014_Pharmacol.Res_83_20
Author(s) : Srinivasan R , Henderson BJ , Lester HA , Richards CI
Ref : Pharmacol Res , 83 :20 , 2014
Abstract : Srinivasan_2014_Pharmacol.Res_83_20
ESTHER : Srinivasan_2014_Pharmacol.Res_83_20
PubMedSearch : Srinivasan_2014_Pharmacol.Res_83_20
PubMedID: 24593907

Title : Probing the non-canonical interface for agonist interaction with an alpha5 containing nicotinic acetylcholine receptor - Marotta_2014_Neuropharmacol_77_342
Author(s) : Marotta CB , Dilworth CN , Lester HA , Dougherty DA
Ref : Neuropharmacology , 77 :342 , 2014
Abstract : Marotta_2014_Neuropharmacol_77_342
ESTHER : Marotta_2014_Neuropharmacol_77_342
PubMedSearch : Marotta_2014_Neuropharmacol_77_342
PubMedID: 24144909

Title : An Unusual Pattern of Ligand-Receptor Interactions for the alpha7 Nicotinic Acetylcholine Receptor, with Implications for the Binding of Varenicline - Van Arnam_2013_Mol.Pharmacol_84_201
Author(s) : Van Arnam EB , Blythe EE , Lester HA , Dougherty DA
Ref : Molecular Pharmacology , 84 :201 , 2013
Abstract : Van Arnam_2013_Mol.Pharmacol_84_201
ESTHER : Van Arnam_2013_Mol.Pharmacol_84_201
PubMedSearch : Van Arnam_2013_Mol.Pharmacol_84_201
PubMedID: 23680636

Title : Mice expressing the ADNFLE valine 287 leucine mutation of the Beta2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function - O'Neill_2013_Pharmacol.Biochem.Behav_103_603
Author(s) : O'Neill HC , Laverty DC , Patzlaff NE , Cohen BN , Fonck C , McKinney S , McIntosh JM , Lindstrom JM , Lester HA , Grady SR , Marks MJ
Ref : Pharmacol Biochem Behav , 103 :603 , 2013
Abstract : O'Neill_2013_Pharmacol.Biochem.Behav_103_603
ESTHER : O'Neill_2013_Pharmacol.Biochem.Behav_103_603
PubMedSearch : O'Neill_2013_Pharmacol.Biochem.Behav_103_603
PubMedID: 23123803

Title : Binding interactions with the complementary subunit of nicotinic receptors - Blum_2013_J.Biol.Chem_288_6991
Author(s) : Blum AP , Van Arnam EB , German LA , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 288 :6991 , 2013
Abstract : Blum_2013_J.Biol.Chem_288_6991
ESTHER : Blum_2013_J.Biol.Chem_288_6991
PubMedSearch : Blum_2013_J.Biol.Chem_288_6991
PubMedID: 23349463

Title : Transcriptional regulation by nicotine in dopaminergic neurons - Henley_2013_Biochem.Pharmacol_86(8)_1074
Author(s) : Henley BM , Williams BA , Srinivasan R , Cohen BN , Xiao C , Mackey ED , Wold BJ , Lester HA
Ref : Biochemical Pharmacology , 86 :1074 , 2013
Abstract : Henley_2013_Biochem.Pharmacol_86(8)_1074
ESTHER : Henley_2013_Biochem.Pharmacol_86(8)_1074
PubMedSearch : Henley_2013_Biochem.Pharmacol_86(8)_1074
PubMedID: 23939186

Title : alpha7beta2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their alpha7-alpha7 interfaces - Murray_2012_Mol.Pharmacol_81_175
Author(s) : Murray TA , Bertrand D , Papke RL , George AA , Pantoja R , Srinivasan R , Liu Q , Wu J , Whiteaker P , Lester HA , Lukas RJ
Ref : Molecular Pharmacology , 81 :175 , 2012
Abstract : Murray_2012_Mol.Pharmacol_81_175
ESTHER : Murray_2012_Mol.Pharmacol_81_175
PubMedSearch : Murray_2012_Mol.Pharmacol_81_175
PubMedID: 22039094

Title : Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations - Drenan_2012_Pharmacol.Rev_64_869
Author(s) : Drenan RM , Lester HA
Ref : Pharmacol Rev , 64 :869 , 2012
Abstract : Drenan_2012_Pharmacol.Rev_64_869
ESTHER : Drenan_2012_Pharmacol.Rev_64_869
PubMedSearch : Drenan_2012_Pharmacol.Rev_64_869
PubMedID: 22885704

Title : alpha6* nicotinic acetylcholine receptor expression and function in a visual salience circuit - Mackey_2012_J.Neurosci_32_10226
Author(s) : Mackey ED , Engle SE , Kim MR , O'Neill HC , Wageman CR , Patzlaff NE , Wang Y , Grady SR , McIntosh JM , Marks MJ , Lester HA , Drenan RM
Ref : Journal of Neuroscience , 32 :10226 , 2012
Abstract : Mackey_2012_J.Neurosci_32_10226
ESTHER : Mackey_2012_J.Neurosci_32_10226
PubMedSearch : Mackey_2012_J.Neurosci_32_10226
PubMedID: 22836257

Title : Forster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic alpha4beta2 - Srinivasan_2012_Int.J.Mol.Sci_13_10022
Author(s) : Srinivasan R , Richards CI , Dilworth C , Moss FJ , Dougherty DA , Lester HA
Ref : Int J Mol Sci , 13 :10022 , 2012
Abstract : Srinivasan_2012_Int.J.Mol.Sci_13_10022
ESTHER : Srinivasan_2012_Int.J.Mol.Sci_13_10022
PubMedSearch : Srinivasan_2012_Int.J.Mol.Sci_13_10022
PubMedID: 22949846

Title : Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response - Srinivasan_2012_Mol.Pharmacol_81_759
Author(s) : Srinivasan R , Richards CI , Xiao C , Rhee D , Pantoja R , Dougherty DA , Miwa JM , Lester HA
Ref : Molecular Pharmacology , 81 :759 , 2012
Abstract : Srinivasan_2012_Mol.Pharmacol_81_759
ESTHER : Srinivasan_2012_Mol.Pharmacol_81_759
PubMedSearch : Srinivasan_2012_Mol.Pharmacol_81_759
PubMedID: 22379121

Title : Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor - Puskar_2012_ACS.Chem.Biol_7_841
Author(s) : Puskar NL , Lester HA , Dougherty DA
Ref : ACS Chemical Biology , 7 :841 , 2012
Abstract : Puskar_2012_ACS.Chem.Biol_7_841
ESTHER : Puskar_2012_ACS.Chem.Biol_7_841
PubMedSearch : Puskar_2012_ACS.Chem.Biol_7_841
PubMedID: 22296725

Title : Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior - Cohen_2012_Neurosci_200_31
Author(s) : Cohen BN , Mackey ED , Grady SR , McKinney S , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA , Drenan RM
Ref : Neuroscience , 200 :31 , 2012
Abstract : Cohen_2012_Neurosci_200_31
ESTHER : Cohen_2012_Neurosci_200_31
PubMedSearch : Cohen_2012_Neurosci_200_31
PubMedID: 22079576

Title : Variations in binding among several agonists at two stoichiometries of the neuronal, alpha4beta2 nicotinic receptor - Tavares_2012_J.Am.Chem.Soc_134_11474
Author(s) : Tavares Xda S , Blum AP , Nakamura DT , Puskar NL , Shanata JA , Lester HA , Dougherty DA
Ref : J Am Chem Soc , 134 :11474 , 2012
Abstract : Tavares_2012_J.Am.Chem.Soc_134_11474
ESTHER : Tavares_2012_J.Am.Chem.Soc_134_11474
PubMedSearch : Tavares_2012_J.Am.Chem.Soc_134_11474
PubMedID: 22716019

Title : Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction - Miwa_2012_Physiology.(Bethesda)_27_187
Author(s) : Miwa JM , Lester HA , Walz A
Ref : Physiology (Bethesda) , 27 :187 , 2012
Abstract : Miwa_2012_Physiology.(Bethesda)_27_187
ESTHER : Miwa_2012_Physiology.(Bethesda)_27_187
PubMedSearch : Miwa_2012_Physiology.(Bethesda)_27_187
PubMedID: 22875450

Title : Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures - Richards_2012_Nano.Lett_12_3690
Author(s) : Richards CI , Luong K , Srinivasan R , Turner SW , Dougherty DA , Korlach J , Lester HA
Ref : Nano Lett , 12 :3690 , 2012
Abstract : Richards_2012_Nano.Lett_12_3690
ESTHER : Richards_2012_Nano.Lett_12_3690
PubMedSearch : Richards_2012_Nano.Lett_12_3690
PubMedID: 22668081

Title : Characterizing functional alpha6beta2 nicotinic acetylcholine receptors in vitro: mutant beta2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells - Xiao_2011_Biochem.Pharmacol_82(8)_852
Author(s) : Xiao C , Srinivasan R , Drenan RM , Mackey ED , McIntosh JM , Lester HA
Ref : Biochemical Pharmacology , 82 :852 , 2011
Abstract : Xiao_2011_Biochem.Pharmacol_82(8)_852
ESTHER : Xiao_2011_Biochem.Pharmacol_82(8)_852
PubMedSearch : Xiao_2011_Biochem.Pharmacol_82(8)_852
PubMedID: 21609715

Title : Evidence for an extended hydrogen bond network in the binding site of the nicotinic receptor: role of the vicinal disulfide of the alpha1 subunit - Blum_2011_J.Biol.Chem_286_32251
Author(s) : Blum AP , Gleitsman KR , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 286 :32251 , 2011
Abstract : Blum_2011_J.Biol.Chem_286_32251
ESTHER : Blum_2011_J.Biol.Chem_286_32251
PubMedSearch : Blum_2011_J.Biol.Chem_286_32251
PubMedID: 21757705

Title : Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor - Lummis_2011_J.Pharmacol.Exp.Ther_339_125
Author(s) : Lummis SC , Thompson AJ , Bencherif M , Lester HA
Ref : Journal of Pharmacology & Experimental Therapeutics , 339 :125 , 2011
Abstract : Lummis_2011_J.Pharmacol.Exp.Ther_339_125
ESTHER : Lummis_2011_J.Pharmacol.Exp.Ther_339_125
PubMedSearch : Lummis_2011_J.Pharmacol.Exp.Ther_339_125
PubMedID: 21775477

Title : Poster: alpha6* nAChR expression and function in brain areas influencing DA transmission probed with alpha6-GFP transgenic mice -
Author(s) : Drenan RM , Mackey EDW , Grady SR , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA
Ref : Biochemical Pharmacology , 82 :1035 , 2011
PubMedID:

Title : A cation-pi interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists - Pless_2011_Mol.Pharmacol_79_742
Author(s) : Pless SA , Hanek AP , Price KL , Lynch JW , Lester HA , Dougherty DA , Lummis SC
Ref : Molecular Pharmacology , 79 :742 , 2011
Abstract : Pless_2011_Mol.Pharmacol_79_742
ESTHER : Pless_2011_Mol.Pharmacol_79_742
PubMedSearch : Pless_2011_Mol.Pharmacol_79_742
PubMedID: 21266487

Title : Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning - Srinivasan_2011_J.Gen.Physiol_137_59
Author(s) : Srinivasan R , Pantoja R , Moss FJ , Mackey ED , Son CD , Miwa JM , Lester HA
Ref : Journal of General Physiology , 137 :59 , 2011
Abstract : Srinivasan_2011_J.Gen.Physiol_137_59
ESTHER : Srinivasan_2011_J.Gen.Physiol_137_59
PubMedSearch : Srinivasan_2011_J.Gen.Physiol_137_59
PubMedID: 21187334

Title : Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes - Puskar_2011_J.Biol.Chem_286_14618
Author(s) : Puskar NL , Xiu X , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 286 :14618 , 2011
Abstract : Puskar_2011_J.Biol.Chem_286_14618
ESTHER : Puskar_2011_J.Biol.Chem_286_14618
PubMedSearch : Puskar_2011_J.Biol.Chem_286_14618
PubMedID: 21343288

Title : Poster: Lynx1 balances neuronal activity through nicotinic acetylcholine receptor modulation -
Author(s) : Parker RL , Rhee DS , Lester HA , Miwa JM
Ref : Biochemical Pharmacology , 82 :1037 , 2011
PubMedID:

Title : Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses - Miwa_2011_Neuron_70_20
Author(s) : Miwa JM , Freedman R , Lester HA
Ref : Neuron , 70 :20 , 2011
Abstract : Miwa_2011_Neuron_70_20
ESTHER : Miwa_2011_Neuron_70_20
PubMedSearch : Miwa_2011_Neuron_70_20
PubMedID: 21482353

Title : Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the beta2 nicotinic receptor - Xu_2011_Mol.Psychiatry_16_1048
Author(s) : Xu J , Cohen BN , Zhu Y , Dziewczapolski G , Panda S , Lester HA , Heinemann SF , Contractor A
Ref : Mol Psychiatry , 16 :1048 , 2011
Abstract : Xu_2011_Mol.Psychiatry_16_1048
ESTHER : Xu_2011_Mol.Psychiatry_16_1048
PubMedSearch : Xu_2011_Mol.Psychiatry_16_1048
PubMedID: 20603624

Title : Trafficking of alpha4* nicotinic receptors revealed by superecliptic phluorin: effects of a beta4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine - Richards_2011_J.Biol.Chem_286_31241
Author(s) : Richards CI , Srinivasan R , Xiao C , Mackey ED , Miwa JM , Lester HA
Ref : Journal of Biological Chemistry , 286 :31241 , 2011
Abstract : Richards_2011_J.Biol.Chem_286_31241
ESTHER : Richards_2011_J.Biol.Chem_286_31241
PubMedSearch : Richards_2011_J.Biol.Chem_286_31241
PubMedID: 21768117

Title : Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors - Grady_2010_Neuropharmacol_58_1054
Author(s) : Grady SR , Drenan RM , Breining SR , Yohannes D , Wageman CR , Fedorov NB , McKinney S , Whiteaker P , Bencherif M , Lester HA , Marks MJ
Ref : Neuropharmacology , 58 :1054 , 2010
Abstract : Grady_2010_Neuropharmacol_58_1054
ESTHER : Grady_2010_Neuropharmacol_58_1054
PubMedSearch : Grady_2010_Neuropharmacol_58_1054
PubMedID: 20114055

Title : Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors - Drenan_2010_J.Neurosci_30_9877
Author(s) : Drenan RM , Grady SR , Steele AD , McKinney S , Patzlaff NE , McIntosh JM , Marks MJ , Miwa JM , Lester HA
Ref : Journal of Neuroscience , 30 :9877 , 2010
Abstract : Drenan_2010_J.Neurosci_30_9877
ESTHER : Drenan_2010_J.Neurosci_30_9877
PubMedSearch : Drenan_2010_J.Neurosci_30_9877
PubMedID: 20660270

Title : Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors - Limapichat_2010_J.Biol.Chem_285_8976
Author(s) : Limapichat W , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 285 :8976 , 2010
Abstract : Limapichat_2010_J.Biol.Chem_285_8976
ESTHER : Limapichat_2010_J.Biol.Chem_285_8976
PubMedSearch : Limapichat_2010_J.Biol.Chem_285_8976
PubMedID: 20068044

Title : Nicotinic pharmacophore: the pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH - Blum_2010_Proc.Natl.Acad.Sci.U.S.A_107_13206
Author(s) : Blum AP , Lester HA , Dougherty DA
Ref : Proc Natl Acad Sci U S A , 107 :13206 , 2010
Abstract : Blum_2010_Proc.Natl.Acad.Sci.U.S.A_107_13206
ESTHER : Blum_2010_Proc.Natl.Acad.Sci.U.S.A_107_13206
PubMedSearch : Blum_2010_Proc.Natl.Acad.Sci.U.S.A_107_13206
PubMedID: 20616056

Title : Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism - Zhao-Shea_2010_FASEB.J_24_49
Author(s) : Zhao-Shea R , Cohen BN , Just H , McClure-Begley TD , Whiteaker P , Grady SR , Salminen O , Gardner PD , Lester HA , Tapper AR
Ref : FASEB Journal , 24 :49 , 2010
Abstract : Zhao-Shea_2010_FASEB.J_24_49
ESTHER : Zhao-Shea_2010_FASEB.J_24_49
PubMedSearch : Zhao-Shea_2010_FASEB.J_24_49
PubMedID: 19720621

Title : Poster: Pharmacological chaperoning of nicotinic receptors begins in the endoplasmic reticulum: High-resolution imaging -
Author(s) : Pantoja R , Srinivasan R , Kadambi S , Mackey EDW , Tzlil S , Moss FJ , Lester HA
Ref : Biochemical Pharmacology , 78 :900 , 2009
PubMedID:

Title : Probing the role of backbone hydrogen bonding in a critical beta sheet of the extracellular domain of a cys-loop receptor - Gleitsman_2009_Chembiochem_10_1385
Author(s) : Gleitsman KR , Lester HA , Dougherty DA
Ref : Chembiochem , 10 :1385 , 2009
Abstract : Gleitsman_2009_Chembiochem_10_1385
ESTHER : Gleitsman_2009_Chembiochem_10_1385
PubMedSearch : Gleitsman_2009_Chembiochem_10_1385
PubMedID: 19405066

Title : Long-range coupling in an allosteric receptor revealed by mutant cycle analysis - Gleitsman_2009_Biophys.J_96_3168
Author(s) : Gleitsman KR , Shanata JA , Frazier SJ , Lester HA , Dougherty DA
Ref : Biophysical Journal , 96 :3168 , 2009
Abstract : Gleitsman_2009_Biophys.J_96_3168
ESTHER : Gleitsman_2009_Biophys.J_96_3168
PubMedSearch : Gleitsman_2009_Biophys.J_96_3168
PubMedID: 19383461

Title : Poster: Pharmacological chaperoning of nicotinic receptors begins in the endoplasmic reticulum: Compartments and stoichiometries -
Author(s) : Srinivasan R , Pantoja R , Kadambi S , Mackey EDW , Tzlil S , Moss FJ , Lester HA
Ref : Biochemical Pharmacology , 78 :900 , 2009
PubMedID:

Title : Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery - Lester_2009_AAPS.J_11_167
Author(s) : Lester HA , Xiao C , Srinivasan R , Son CD , Miwa JM , Pantoja R , Banghart MR , Dougherty DA , Goate AM , Wang JC
Ref : AAPS J , 11 :167 , 2009
Abstract : Lester_2009_AAPS.J_11_167
ESTHER : Lester_2009_AAPS.J_11_167
PubMedSearch : Lester_2009_AAPS.J_11_167
PubMedID: 19280351

Title : Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors - Pantoja_2009_Biophys.J_96_226
Author(s) : Pantoja R , Rodriguez EA , Dibas MI , Dougherty DA , Lester HA
Ref : Biophysical Journal , 96 :226 , 2009
Abstract : Pantoja_2009_Biophys.J_96_226
ESTHER : Pantoja_2009_Biophys.J_96_226
PubMedSearch : Pantoja_2009_Biophys.J_96_226
PubMedID: 19134478

Title : Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype - Breining_2009_Bioorg.Med.Chem.Lett_19_4359
Author(s) : Breining SR , Bencherif M , Grady SR , Whiteaker P , Marks MJ , Wageman CR , Lester HA , Yohannes D
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4359 , 2009
Abstract : Breining_2009_Bioorg.Med.Chem.Lett_19_4359
ESTHER : Breining_2009_Bioorg.Med.Chem.Lett_19_4359
PubMedSearch : Breining_2009_Bioorg.Med.Chem.Lett_19_4359
PubMedID: 19560354

Title : Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway - Xiao_2009_J.Neurosci_29_12428
Author(s) : Xiao C , Nashmi R , McKinney S , Cai H , McIntosh JM , Lester HA
Ref : Journal of Neuroscience , 29 :12428 , 2009
Abstract : Xiao_2009_J.Neurosci_29_12428
ESTHER : Xiao_2009_J.Neurosci_29_12428
PubMedSearch : Xiao_2009_J.Neurosci_29_12428
PubMedID: 19812319

Title : Nicotine binding to brain receptors requires a strong cation-pi interaction - Xiu_2009_Nature_458_534
Author(s) : Xiu X , Puskar NL , Shanata JA , Lester HA , Dougherty DA
Ref : Nature , 458 :534 , 2009
Abstract : Xiu_2009_Nature_458_534
ESTHER : Xiu_2009_Nature_458_534
PubMedSearch : Xiu_2009_Nature_458_534
PubMedID: 19252481

Title : Demonstration of functional alpha4-containing nicotinic receptors in the medial habenula - Fonck_2009_Neuropharmacol_56_247
Author(s) : Fonck C , Nashmi R , Salas R , Zhou C , Huang Q , De Biasi M , Lester RA , Lester HA
Ref : Neuropharmacology , 56 :247 , 2009
Abstract : Fonck_2009_Neuropharmacol_56_247
ESTHER : Fonck_2009_Neuropharmacol_56_247
PubMedSearch : Fonck_2009_Neuropharmacol_56_247
PubMedID: 18789953

Title : Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids - Torrice_2009_Proc.Natl.Acad.Sci.U.S.A_106_11919
Author(s) : Torrice MM , Bower KS , Lester HA , Dougherty DA
Ref : Proc Natl Acad Sci U S A , 106 :11919 , 2009
Abstract : Torrice_2009_Proc.Natl.Acad.Sci.U.S.A_106_11919
ESTHER : Torrice_2009_Proc.Natl.Acad.Sci.U.S.A_106_11919
PubMedSearch : Torrice_2009_Proc.Natl.Acad.Sci.U.S.A_106_11919
PubMedID: 19581583

Title : An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating - Gleitsman_2008_J.Biol.Chem_283_35638
Author(s) : Gleitsman KR , Kedrowski SM , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 283 :35638 , 2008
Abstract : Gleitsman_2008_J.Biol.Chem_283_35638
ESTHER : Gleitsman_2008_J.Biol.Chem_283_35638
PubMedSearch : Gleitsman_2008_J.Biol.Chem_283_35638
PubMedID: 18952603

Title : In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors - Drenan_2008_Neuron_60_123
Author(s) : Drenan RM , Grady SR , Whiteaker P , McClure-Begley TD , McKinney S , Miwa JM , Bupp S , Heintz N , McIntosh JM , Bencherif M , Marks MJ , Lester HA
Ref : Neuron , 60 :123 , 2008
Abstract : Drenan_2008_Neuron_60_123
ESTHER : Drenan_2008_Neuron_60_123
PubMedSearch : Drenan_2008_Neuron_60_123
PubMedID: 18940593

Title : Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled alpha6 and beta3 subunits - Drenan_2008_Mol.Pharmacol_73_27
Author(s) : Drenan RM , Nashmi R , Imoukhuede P , Just H , McKinney S , Lester HA
Ref : Molecular Pharmacology , 73 :27 , 2008
Abstract : Drenan_2008_Mol.Pharmacol_73_27
ESTHER : Drenan_2008_Mol.Pharmacol_73_27
PubMedSearch : Drenan_2008_Mol.Pharmacol_73_27
PubMedID: 17932221

Title : A stereochemical test of a proposed structural feature of the nicotinic acetylcholine receptor - Hanek_2008_J.Am.Chem.Soc_130_13216
Author(s) : Hanek AP , Lester HA , Dougherty DA
Ref : J Am Chem Soc , 130 :13216 , 2008
Abstract : Hanek_2008_J.Am.Chem.Soc_130_13216
ESTHER : Hanek_2008_J.Am.Chem.Soc_130_13216
PubMedSearch : Hanek_2008_J.Am.Chem.Soc_130_13216
PubMedID: 18781739

Title : Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic\/nicotinic modulation of respiratory rhythm - Shao_2008_J.Neurosci_28_519
Author(s) : Shao XM , Tan W , Xiu J , Puskar N , Fonck C , Lester HA , Feldman JL
Ref : Journal of Neuroscience , 28 :519 , 2008
Abstract : Shao_2008_J.Neurosci_28_519
ESTHER : Shao_2008_J.Neurosci_28_519
PubMedSearch : Shao_2008_J.Neurosci_28_519
PubMedID: 18184794

Title : Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path - Nashmi_2007_J.Neurosci_27_8202
Author(s) : Nashmi R , Xiao C , Deshpande P , McKinney S , Grady SR , Whiteaker P , Huang Q , McClure-Begley TD , Lindstrom JM , Labarca C , Collins AC , Marks MJ , Lester HA
Ref : Journal of Neuroscience , 27 :8202 , 2007
Abstract : Nashmi_2007_J.Neurosci_27_8202
ESTHER : Nashmi_2007_J.Neurosci_27_8202
PubMedSearch : Nashmi_2007_J.Neurosci_27_8202
PubMedID: 17670967

Title : Chemical-scale studies on the role of a conserved aspartate in preorganizing the agonist binding site of the nicotinic acetylcholine receptor - Cashin_2007_Biochemistry_46_630
Author(s) : Cashin AL , Torrice MM , McMenimen KA , Lester HA , Dougherty DA
Ref : Biochemistry , 46 :630 , 2007
Abstract : Cashin_2007_Biochemistry_46_630
ESTHER : Cashin_2007_Biochemistry_46_630
PubMedSearch : Cashin_2007_Biochemistry_46_630
PubMedID: 17223685

Title : Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation - Nashmi_2007_Biochem.Pharmacol_74(8)_1145
Author(s) : Nashmi R , Lester HA
Ref : Biochemical Pharmacology , 74 :1145 , 2007
Abstract : Nashmi_2007_Biochem.Pharmacol_74(8)_1145
ESTHER : Nashmi_2007_Biochem.Pharmacol_74(8)_1145
PubMedSearch : Nashmi_2007_Biochem.Pharmacol_74(8)_1145
PubMedID: 17662697

Title : Nicotine responses in hypersensitive and knockout alpha 4 mice account for tolerance to both hypothermia and locomotor suppression in wild-type mice - Tapper_2007_Physiol.Genomics_31_422
Author(s) : Tapper AR , McKinney SL , Marks MJ , Lester HA
Ref : Physiol Genomics , 31 :422 , 2007
Abstract : Tapper_2007_Physiol.Genomics_31_422
ESTHER : Tapper_2007_Physiol.Genomics_31_422
PubMedSearch : Tapper_2007_Physiol.Genomics_31_422
PubMedID: 17712039

Title : Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation - Teper_2007_J.Neurosci_27_10128
Author(s) : Teper Y , Whyte D , Cahir E , Lester HA , Grady SR , Marks MJ , Cohen BN , Fonck C , McClure-Begley TD , McIntosh JM , Labarca C , Lawrence A , Chen F , Gantois I , Davies PJ , Petrou S , Murphy M , Waddington J , Horne MK , Berkovic SF , Drago J
Ref : Journal of Neuroscience , 27 :10128 , 2007
Abstract : Teper_2007_J.Neurosci_27_10128
ESTHER : Teper_2007_J.Neurosci_27_10128
PubMedSearch : Teper_2007_J.Neurosci_27_10128
PubMedID: 17881519

Title : Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice - Damaj_2007_J.Pharmacol.Exp.Ther_321_1161
Author(s) : Damaj MI , Fonck C , Marks MJ , Deshpande P , Labarca C , Lester HA , Collins AC , Martin BR
Ref : Journal of Pharmacology & Experimental Therapeutics , 321 :1161 , 2007
Abstract : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161
ESTHER : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161
PubMedSearch : Damaj_2007_J.Pharmacol.Exp.Ther_321_1161
PubMedID: 17371806

Title : CNS localization of neuronal nicotinic receptors - Nashmi_2006_J.Mol.Neurosci_30_181
Author(s) : Nashmi R , Lester HA
Ref : Journal of Molecular Neuroscience , 30 :181 , 2006
Abstract : Nashmi_2006_J.Mol.Neurosci_30_181
ESTHER : Nashmi_2006_J.Mol.Neurosci_30_181
PubMedSearch : Nashmi_2006_J.Mol.Neurosci_30_181
PubMedID: 17192671

Title : Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons - Schwarz_2006_FASEB.J_20_935
Author(s) : Schwarz J , Schwarz SC , Dorigo O , Stutzer A , Wegner F , Labarca C , Deshpande P , Gil JS , Berk AJ , Lester HA
Ref : FASEB Journal , 20 :935 , 2006
Abstract : Schwarz_2006_FASEB.J_20_935
ESTHER : Schwarz_2006_FASEB.J_20_935
PubMedSearch : Schwarz_2006_FASEB.J_20_935
PubMedID: 16675851

Title : The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo - Miwa_2006_Neuron_51_587
Author(s) : Miwa JM , Stevens TR , King SL , Caldarone BJ , Ibanez-Tallon I , Xiao C , Fitzsimonds RM , Pavlides C , Lester HA , Picciotto MR , Heintz N
Ref : Neuron , 51 :587 , 2006
Abstract : Miwa_2006_Neuron_51_587
ESTHER : Miwa_2006_Neuron_51_587
PubMedSearch : Miwa_2006_Neuron_51_587
PubMedID: 16950157

Title : Mutations linked to autosomal dominant nocturnal frontal lobe epilepsy affect allosteric Ca2+ activation of the alpha 4 beta 2 nicotinic acetylcholine receptor - Rodrigues-Pinguet_2005_Mol.Pharmacol_68_487
Author(s) : Rodrigues-Pinguet NO , Pinguet TJ , Figl A , Lester HA , Cohen BN
Ref : Molecular Pharmacology , 68 :487 , 2005
Abstract : Rodrigues-Pinguet_2005_Mol.Pharmacol_68_487
ESTHER : Rodrigues-Pinguet_2005_Mol.Pharmacol_68_487
PubMedSearch : Rodrigues-Pinguet_2005_Mol.Pharmacol_68_487
PubMedID: 15901849

Title : A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor - Lummis_2005_Chem.Biol_12_993
Author(s) : Lummis SC , D LB , Harrison NJ , Lester HA , Dougherty DA
Ref : Chemical Biology , 12 :993 , 2005
Abstract : Lummis_2005_Chem.Biol_12_993
ESTHER : Lummis_2005_Chem.Biol_12_993
PubMedSearch : Lummis_2005_Chem.Biol_12_993
PubMedID: 16183023

Title : Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor - Cashin_2005_J.Am.Chem.Soc_127_350
Author(s) : Cashin AL , Petersson EJ , Lester HA , Dougherty DA
Ref : J Am Chem Soc , 127 :350 , 2005
Abstract : Cashin_2005_J.Am.Chem.Soc_127_350
ESTHER : Cashin_2005_J.Am.Chem.Soc_127_350
PubMedSearch : Cashin_2005_J.Am.Chem.Soc_127_350
PubMedID: 15631485

Title : A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors - Xiu_2005_J.Biol.Chem_280_41655
Author(s) : Xiu X , Hanek AP , Wang J , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 280 :41655 , 2005
Abstract : Xiu_2005_J.Biol.Chem_280_41655
ESTHER : Xiu_2005_J.Biol.Chem_280_41655
PubMedSearch : Xiu_2005_J.Biol.Chem_280_41655
PubMedID: 16216879

Title : Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors - Fonck_2005_J.Neurosci_25_11396
Author(s) : Fonck C , Cohen BN , Nashmi R , Whiteaker P , Wagenaar DA , Rodrigues-Pinguet N , Deshpande P , McKinney S , Kwoh S , Munoz J , Labarca C , Collins AC , Marks MJ , Lester HA
Ref : Journal of Neuroscience , 25 :11396 , 2005
Abstract : Fonck_2005_J.Neurosci_25_11396
ESTHER : Fonck_2005_J.Neurosci_25_11396
PubMedSearch : Fonck_2005_J.Neurosci_25_11396
PubMedID: 16339034

Title : Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit - Bhattacharya_2004_J.Neurosci_24_5537
Author(s) : Bhattacharya A , Dang H , Zhu QM , Schnegelsberg B , Rozengurt N , Cain G , Prantil R , Vorp DA , Guy N , Julius D , Ford AP , Lester HA , Cockayne DA
Ref : Journal of Neuroscience , 24 :5537 , 2004
Abstract : Bhattacharya_2004_J.Neurosci_24_5537
ESTHER : Bhattacharya_2004_J.Neurosci_24_5537
PubMedSearch : Bhattacharya_2004_J.Neurosci_24_5537
PubMedID: 15201326

Title : Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally - Orb_2004_Physiol.Genomics_18_299
Author(s) : Orb S , Wieacker J , Labarca C , Fonck C , Lester HA , Schwarz J
Ref : Physiol Genomics , 18 :299 , 2004
Abstract : Orb_2004_Physiol.Genomics_18_299
ESTHER : Orb_2004_Physiol.Genomics_18_299
PubMedSearch : Orb_2004_Physiol.Genomics_18_299
PubMedID: 15199190

Title : Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization - Tapper_2004_Science_306_1029
Author(s) : Tapper AR , McKinney SL , Nashmi R , Schwarz J , Deshpande P , Labarca C , Whiteaker P , Marks MJ , Collins AC , Lester HA
Ref : Science , 306 :1029 , 2004
Abstract : Tapper_2004_Science_306_1029
ESTHER : Tapper_2004_Science_306_1029
PubMedSearch : Tapper_2004_Science_306_1029
PubMedID: 15528443

Title : A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site - Dahan_2004_Proc.Natl.Acad.Sci.U.S.A_101_10195
Author(s) : Dahan DS , Dibas MI , Petersson EJ , Auyeung VC , Chanda B , Bezanilla F , Dougherty DA , Lester HA
Ref : Proc Natl Acad Sci U S A , 101 :10195 , 2004
Abstract : Dahan_2004_Proc.Natl.Acad.Sci.U.S.A_101_10195
ESTHER : Dahan_2004_Proc.Natl.Acad.Sci.U.S.A_101_10195
PubMedSearch : Dahan_2004_Proc.Natl.Acad.Sci.U.S.A_101_10195
PubMedID: 15218096

Title : Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometry - Leite_2003_Proc.Natl.Acad.Sci.U.S.A_100_13054
Author(s) : Leite JF , Blanton MP , Shahgholi M , Dougherty DA , Lester HA
Ref : Proc Natl Acad Sci U S A , 100 :13054 , 2003
Abstract : Leite_2003_Proc.Natl.Acad.Sci.U.S.A_100_13054
ESTHER : Leite_2003_Proc.Natl.Acad.Sci.U.S.A_100_13054
PubMedSearch : Leite_2003_Proc.Natl.Acad.Sci.U.S.A_100_13054
PubMedID: 14569028

Title : Investigation of apparent mass deviations in electrospray ionization tandem mass spectrometry of a benzophenone-labeled peptide - Leite_2003_Rapid.Commun.Mass.Spectrom_17_1677
Author(s) : Leite JF , Dougherty DA , Lester HA , Shahgholi M
Ref : Rapid Commun Mass Spectrom , 17 :1677 , 2003
Abstract : Leite_2003_Rapid.Commun.Mass.Spectrom_17_1677
ESTHER : Leite_2003_Rapid.Commun.Mass.Spectrom_17_1677
PubMedSearch : Leite_2003_Rapid.Commun.Mass.Spectrom_17_1677
PubMedID: 12872270

Title : Site-specific incorporation of unnatural amino acids into receptors expressed in Mammalian cells - Monahan_2003_Chem.Biol_10_573
Author(s) : Monahan SL , Lester HA , Dougherty DA
Ref : Chemical Biology , 10 :573 , 2003
Abstract : Monahan_2003_Chem.Biol_10_573
ESTHER : Monahan_2003_Chem.Biol_10_573
PubMedSearch : Monahan_2003_Chem.Biol_10_573
PubMedID: 12837390

Title : Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action - Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633
Author(s) : Lester HA , Fonck C , Tapper AR , McKinney S , Damaj MI , Balogh S , Owens J , Wehner JM , Collins AC , Labarca C
Ref : Curr Opin Drug Discov Devel , 6 :633 , 2003
Abstract : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633
ESTHER : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633
PubMedSearch : Lester_2003_Curr.Opin.Drug.Discov.Devel_6_633
PubMedID: 14579512

Title : Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons - Nashmi_2003_J.Neurosci_23_11554
Author(s) : Nashmi R , Dickinson ME , McKinney S , Jareb M , Labarca C , Fraser SE , Lester HA
Ref : Journal of Neuroscience , 23 :11554 , 2003
Abstract : Nashmi_2003_J.Neurosci_23_11554
ESTHER : Nashmi_2003_J.Neurosci_23_11554
PubMedSearch : Nashmi_2003_J.Neurosci_23_11554
PubMedID: 14684858

Title : Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response - Owens_2003_Alcohol.Clin.Exp.Res_27_1867
Author(s) : Owens JC , Balogh SA , McClure-Begley TD , Butt CM , Labarca C , Lester HA , Picciotto MR , Wehner JM , Collins AC
Ref : Alcohol Clin Exp Res , 27 :1867 , 2003
Abstract : Owens_2003_Alcohol.Clin.Exp.Res_27_1867
ESTHER : Owens_2003_Alcohol.Clin.Exp.Res_27_1867
PubMedSearch : Owens_2003_Alcohol.Clin.Exp.Res_27_1867
PubMedID: 14691373

Title : Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors - Fonck_2003_J.Neurosci_23_2582
Author(s) : Fonck C , Nashmi R , Deshpande P , Damaj MI , Marks MJ , Riedel A , Schwarz J , Collins AC , Labarca C , Lester HA
Ref : Journal of Neuroscience , 23 :2582 , 2003
Abstract : Fonck_2003_J.Neurosci_23_2582
ESTHER : Fonck_2003_J.Neurosci_23_2582
PubMedSearch : Fonck_2003_J.Neurosci_23_2582
PubMedID: 12684443

Title : Five ADNFLE mutations reduce the Ca2+ dependence of the mammalian alpha4beta2 acetylcholine response - Rodrigues-Pinguet_2003_J.Physiol_550_11
Author(s) : Rodrigues-Pinguet N , Jia L , Li M , Figl A , Klaassen A , Truong A , Lester HA , Cohen BN
Ref : The Journal of Physiology , 550 :11 , 2003
Abstract : Rodrigues-Pinguet_2003_J.Physiol_550_11
ESTHER : Rodrigues-Pinguet_2003_J.Physiol_550_11
PubMedSearch : Rodrigues-Pinguet_2003_J.Physiol_550_11
PubMedID: 12754307

Title : Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine - Beene_2002_Biochemistry_41_10262
Author(s) : Beene DL , Brandt GS , Zhong W , Zacharias NM , Lester HA , Dougherty DA
Ref : Biochemistry , 41 :10262 , 2002
Abstract : Beene_2002_Biochemistry_41_10262
ESTHER : Beene_2002_Biochemistry_41_10262
PubMedSearch : Beene_2002_Biochemistry_41_10262
PubMedID: 12162741

Title : Selective elimination of glutamate activation and introduction of fluorescent proteins into a Caenorhabditis elegans chloride channel - Li_2002_FEBS.Lett_528_77
Author(s) : Li P , Slimko EM , Lester HA
Ref : FEBS Letters , 528 :77 , 2002
Abstract : Li_2002_FEBS.Lett_528_77
ESTHER : Li_2002_FEBS.Lett_528_77
PubMedSearch : Li_2002_FEBS.Lett_528_77
PubMedID: 12297283

Title : A perturbed pK(a) at the binding site of the nicotinic acetylcholine receptor: implications for nicotine binding - Petersson_2002_J.Am.Chem.Soc_124_12662
Author(s) : Petersson EJ , Choi A , Dahan DS , Lester HA , Dougherty DA
Ref : J Am Chem Soc , 124 :12662 , 2002
Abstract : Petersson_2002_J.Am.Chem.Soc_124_12662
ESTHER : Petersson_2002_J.Am.Chem.Soc_124_12662
PubMedSearch : Petersson_2002_J.Am.Chem.Soc_124_12662
PubMedID: 12392404

Title : Neurobiology. Snails, synapses and smokers -
Author(s) : Dougherty DA , Lester HA
Ref : Nature , 411 :252 , 2001
PubMedID: 11357112

Title : The tethered agonist approach to mapping ion channel proteins--toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor - Li_2001_Chem.Biol_8_47
Author(s) : Li L , Zhong W , Zacharias N , Gibbs C , Lester HA , Dougherty DA
Ref : Chemical Biology , 8 :47 , 2001
Abstract : Li_2001_Chem.Biol_8_47
ESTHER : Li_2001_Chem.Biol_8_47
PubMedSearch : Li_2001_Chem.Biol_8_47
PubMedID: 11182318

Title : Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety - Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786
Author(s) : Labarca C , Schwarz J , Deshpande P , Schwarz S , Nowak MW , Fonck C , Nashmi R , Kofuji P , Dang H , Shi W , Fidan M , Khakh BS , Chen Z , Bowers BJ , Boulter J , Wehner JM , Lester HA
Ref : Proc Natl Acad Sci U S A , 98 :2786 , 2001
Abstract : Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786
ESTHER : Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786
PubMedSearch : Labarca_2001_Proc.Natl.Acad.Sci.U.S.A_98_2786
PubMedID: 11226318

Title : State-dependent cross-inhibition between transmitter-gated cation channels - Khakh_2000_Nature_406_405
Author(s) : Khakh BS , Zhou X , Sydes J , Galligan JJ , Lester HA
Ref : Nature , 406 :405 , 2000
Abstract : Khakh_2000_Nature_406_405
ESTHER : Khakh_2000_Nature_406_405
PubMedSearch : Khakh_2000_Nature_406_405
PubMedID: 10935636

Title : Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins - Kovoor_2000_J.Biol.Chem_275_3397
Author(s) : Kovoor A , Chen CK , He W , Wensel TG , Simon MI , Lester HA
Ref : Journal of Biological Chemistry , 275 :3397 , 2000
Abstract : Kovoor_2000_J.Biol.Chem_275_3397
ESTHER : Kovoor_2000_J.Biol.Chem_275_3397
PubMedSearch : Kovoor_2000_J.Biol.Chem_275_3397
PubMedID: 10652332

Title : Mapping disulfide connectivity using backbone ester hydrolysis - England_1999_Biochemistry_38_14409
Author(s) : England PM , Lester HA , Dougherty DA
Ref : Biochemistry , 38 :14409 , 1999
Abstract : England_1999_Biochemistry_38_14409
ESTHER : England_1999_Biochemistry_38_14409
PubMedSearch : England_1999_Biochemistry_38_14409
PubMedID: 10572015

Title : Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating - England_1999_Cell_96_89
Author(s) : England PM , Zhang Y , Dougherty DA , Lester HA
Ref : Cell , 96 :89 , 1999
Abstract : England_1999_Cell_96_89
ESTHER : England_1999_Cell_96_89
PubMedSearch : England_1999_Cell_96_89
PubMedID: 9989500

Title : From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor - Zhong_1998_Proc.Natl.Acad.Sci.U.S.A_95_12088
Author(s) : Zhong W , Gallivan JP , Zhang Y , Li L , Lester HA , Dougherty DA
Ref : Proc Natl Acad Sci U S A , 95 :12088 , 1998
Abstract : Zhong_1998_Proc.Natl.Acad.Sci.U.S.A_95_12088
ESTHER : Zhong_1998_Proc.Natl.Acad.Sci.U.S.A_95_12088
PubMedSearch : Zhong_1998_Proc.Natl.Acad.Sci.U.S.A_95_12088
PubMedID: 9770444

Title : Flash decaging of tyrosine sidechains in an ion channel - Miller_1998_Neuron_20_619
Author(s) : Miller JC , Silverman SK , England PM , Dougherty DA , Lester HA
Ref : Neuron , 20 :619 , 1998
Abstract : Miller_1998_Neuron_20_619
ESTHER : Miller_1998_Neuron_20_619
PubMedSearch : Miller_1998_Neuron_20_619
PubMedID: 9581754

Title : RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels - Doupnik_1997_Proc.Natl.Acad.Sci.U.S.A_94_10461
Author(s) : Doupnik CA , Davidson N , Lester HA , Kofuji P
Ref : Proc Natl Acad Sci U S A , 94 :10461 , 1997
Abstract : Doupnik_1997_Proc.Natl.Acad.Sci.U.S.A_94_10461
ESTHER : Doupnik_1997_Proc.Natl.Acad.Sci.U.S.A_94_10461
PubMedSearch : Doupnik_1997_Proc.Natl.Acad.Sci.U.S.A_94_10461
PubMedID: 9294233

Title : Expression and circular dichroism studies of the extracellular domain of the alpha subunit of the nicotinic acetylcholine receptor - West_1997_J.Biol.Chem_272_25468
Author(s) : West AP, Jr. , Bjorkman PJ , Dougherty DA , Lester HA
Ref : Journal of Biological Chemistry , 272 :25468 , 1997
Abstract : West_1997_J.Biol.Chem_272_25468
ESTHER : West_1997_J.Biol.Chem_272_25468
PubMedSearch : West_1997_J.Biol.Chem_272_25468
PubMedID: 9325259

Title : Site-specific, photochemical proteolysis applied to ion channels in vivo - England_1997_Proc.Natl.Acad.Sci.U.S.A_94_11025
Author(s) : England PM , Lester HA , Davidson N , Dougherty DA
Ref : Proc Natl Acad Sci U S A , 94 :11025 , 1997
Abstract : England_1997_Proc.Natl.Acad.Sci.U.S.A_94_11025
ESTHER : England_1997_Proc.Natl.Acad.Sci.U.S.A_94_11025
PubMedSearch : England_1997_Proc.Natl.Acad.Sci.U.S.A_94_11025
PubMedID: 9380753

Title : Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins - Gallivan JP_1997_Chem.Biol_4_739
Author(s) : Gallivan JP , Lester HA , Dougherty DA
Ref : Chemical Biology , 4 :739 , 1997
Abstract : Gallivan JP_1997_Chem.Biol_4_739
ESTHER : Gallivan JP_1997_Chem.Biol_4_739
PubMedSearch : Gallivan JP_1997_Chem.Biol_4_739
PubMedID: 9375252

Title : An engineered Tetrahymena tRNAGln for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression - Saks_1996_J.Biol.Chem_271_23169
Author(s) : Saks ME , Sampson JR , Nowak MW , Kearney PC , Du F , Abelson JN , Lester HA , Dougherty DA
Ref : Journal of Biological Chemistry , 271 :23169 , 1996
Abstract : Saks_1996_J.Biol.Chem_271_23169
ESTHER : Saks_1996_J.Biol.Chem_271_23169
PubMedSearch : Saks_1996_J.Biol.Chem_271_23169
PubMedID: 8798511

Title : Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits - Schreibmayer_1996_Nature_380_624
Author(s) : Schreibmayer W , Dessauer CW , Vorobiov D , Gilman AG , Lester HA , Davidson N , Dascal N
Ref : Nature , 380 :624 , 1996
Abstract : Schreibmayer_1996_Nature_380_624
ESTHER : Schreibmayer_1996_Nature_380_624
PubMedSearch : Schreibmayer_1996_Nature_380_624
PubMedID: 8602262

Title : A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation - Silverman_1996_Proc.Natl.Acad.Sci.U.S.A_93_15429
Author(s) : Silverman SK , Kofuji P , Dougherty DA , Davidson N , Lester HA
Ref : Proc Natl Acad Sci U S A , 93 :15429 , 1996
Abstract : Silverman_1996_Proc.Natl.Acad.Sci.U.S.A_93_15429
ESTHER : Silverman_1996_Proc.Natl.Acad.Sci.U.S.A_93_15429
PubMedSearch : Silverman_1996_Proc.Natl.Acad.Sci.U.S.A_93_15429
PubMedID: 8986828

Title : Voltage-jump relaxation kinetics for wild-type and chimeric beta subunits of neuronal nicotinic receptors - Figl_1996_J.Gen.Physiol_107_369
Author(s) : Figl A , Labarca C , Davidson N , Lester HA , Cohen BN
Ref : Journal of General Physiology , 107 :369 , 1996
Abstract : Figl_1996_J.Gen.Physiol_107_369
ESTHER : Figl_1996_J.Gen.Physiol_107_369
PubMedSearch : Figl_1996_J.Gen.Physiol_107_369
PubMedID: 8868048

Title : Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists - Kearney_1996_Mol.Pharmacol_50_1401
Author(s) : Kearney PC , Nowak MW , Zhong W , Silverman SK , Lester HA , Dougherty DA
Ref : Molecular Pharmacology , 50 :1401 , 1996
Abstract : Kearney_1996_Mol.Pharmacol_50_1401
ESTHER : Kearney_1996_Mol.Pharmacol_50_1401
PubMedSearch : Kearney_1996_Mol.Pharmacol_50_1401
PubMedID: 8913372

Title : Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9' position - Kearney_1996_Neuron_17_1221
Author(s) : Kearney PC , Zhang H , Zhong W , Dougherty DA , Lester HA
Ref : Neuron , 17 :1221 , 1996
Abstract : Kearney_1996_Neuron_17_1221
ESTHER : Kearney_1996_Neuron_17_1221
PubMedSearch : Kearney_1996_Neuron_17_1221
PubMedID: 8982168

Title : Activation of ion channels by acetylcholine: two contrasting transduction pathways -
Author(s) : Lester HA
Ref : Harvey Lect , 91 :79 , 1995
PubMedID: 9127987

Title : Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors - Cohen_1995_J.Gen.Physiol_105_745
Author(s) : Cohen BN , Figl A , Quick MW , Labarca C , Davidson N , Lester HA
Ref : Journal of General Physiology , 105 :745 , 1995
Abstract : Cohen_1995_J.Gen.Physiol_105_745
ESTHER : Cohen_1995_J.Gen.Physiol_105_745
PubMedSearch : Cohen_1995_J.Gen.Physiol_105_745
PubMedID: 7561742

Title : Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers - Kofuji_1995_Proc.Natl.Acad.Sci.U.S.A_92_6542
Author(s) : Kofuji P , Davidson N , Lester HA
Ref : Proc Natl Acad Sci U S A , 92 :6542 , 1995
Abstract : Kofuji_1995_Proc.Natl.Acad.Sci.U.S.A_92_6542
ESTHER : Kofuji_1995_Proc.Natl.Acad.Sci.U.S.A_92_6542
PubMedSearch : Kofuji_1995_Proc.Natl.Acad.Sci.U.S.A_92_6542
PubMedID: 7604029

Title : Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors - Labarca_1995_Nature_376_514
Author(s) : Labarca C , Nowak MW , Zhang H , Tang L , Deshpande P , Lester HA
Ref : Nature , 376 :514 , 1995
Abstract : Labarca_1995_Nature_376_514
ESTHER : Labarca_1995_Nature_376_514
PubMedSearch : Labarca_1995_Nature_376_514
PubMedID: 7637783

Title : Fast inhibition of inwardly rectifying K+ channels by multiple neurotransmitter receptors in oligodendroglia - Karschin_1994_Eur.J.Neurosci_6_1756
Author(s) : Karschin A , Wischmeyer E , Davidson N , Lester HA
Ref : European Journal of Neuroscience , 6 :1756 , 1994
Abstract : Karschin_1994_Eur.J.Neurosci_6_1756
ESTHER : Karschin_1994_Eur.J.Neurosci_6_1756
PubMedSearch : Karschin_1994_Eur.J.Neurosci_6_1756
PubMedID: 7874315

Title : Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes - Dascal_1993_Proc.Natl.Acad.Sci.U.S.A_90_6596
Author(s) : Dascal N , Lim NF , Schreibmayer W , Wang W , Davidson N , Lester HA
Ref : Proc Natl Acad Sci U S A , 90 :6596 , 1993
Abstract : Dascal_1993_Proc.Natl.Acad.Sci.U.S.A_90_6596
ESTHER : Dascal_1993_Proc.Natl.Acad.Sci.U.S.A_90_6596
PubMedSearch : Dascal_1993_Proc.Natl.Acad.Sci.U.S.A_90_6596
PubMedID: 8341673

Title : Potassium channels. The response to vagusstoff -
Author(s) : Lester HA , Dascal N
Ref : Nature , 364 :758 , 1993
PubMedID: 8355802

Title : Regions of beta 4.beta 2 subunit chimeras that contribute to the agonist selectivity of neuronal nicotinic receptors - Figl_1992_FEBS.Lett_308_245
Author(s) : Figl A , Cohen BN , Quick MW , Davidson N , Lester HA
Ref : FEBS Letters , 308 :245 , 1992
Abstract : Figl_1992_FEBS.Lett_308_245
ESTHER : Figl_1992_FEBS.Lett_308_245
PubMedSearch : Figl_1992_FEBS.Lett_308_245
PubMedID: 1505662

Title : Pharmacological and kinetic properties of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes - Charnet_1992_J.Physiol_450_375
Author(s) : Charnet P , Labarca C , Cohen BN , Davidson N , Lester HA , Pilar G
Ref : The Journal of Physiology , 450 :375 , 1992
Abstract : Charnet_1992_J.Physiol_450_375
ESTHER : Charnet_1992_J.Physiol_450_375
PubMedSearch : Charnet_1992_J.Physiol_450_375
PubMedID: 1359123

Title : Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission - Charnet_1992_Mol.Pharmacol_41_708
Author(s) : Charnet P , Labarca C , Lester HA
Ref : Molecular Pharmacology , 41 :708 , 1992
Abstract : Charnet_1992_Mol.Pharmacol_41_708
ESTHER : Charnet_1992_Mol.Pharmacol_41_708
PubMedSearch : Charnet_1992_Mol.Pharmacol_41_708
PubMedID: 1373800

Title : Tris+\/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region - Cohen_1992_J.Gen.Physiol_99_545
Author(s) : Cohen BN , Labarca C , Czyzyk L , Davidson N , Lester HA
Ref : Journal of General Physiology , 99 :545 , 1992
Abstract : Cohen_1992_J.Gen.Physiol_99_545
ESTHER : Cohen_1992_J.Gen.Physiol_99_545
PubMedSearch : Cohen_1992_J.Gen.Physiol_99_545
PubMedID: 1597678

Title : Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations - Cohen_1992_J.Gen.Physiol_100_373
Author(s) : Cohen BN , Labarca C , Davidson N , Lester HA
Ref : Journal of General Physiology , 100 :373 , 1992
Abstract : Cohen_1992_J.Gen.Physiol_100_373
ESTHER : Cohen_1992_J.Gen.Physiol_100_373
PubMedSearch : Cohen_1992_J.Gen.Physiol_100_373
PubMedID: 1431803

Title : Mutations affecting local anesthetic block of the nicotinic acetylcholine receptor ion channel -
Author(s) : Leonard RJ , Charnet P , Labarca C , Vogelaar NJ , Czyzyk L , Gouin A , Davidson N , Lester HA
Ref : NIDA Res Monogr , 111 :28 , 1991
PubMedID: 1723151

Title : Reverse pharmacology of the nicotinic acetylcholine receptor. Mapping the local anesthetic binding site - Leonard_1991_Ann.N.Y.Acad.Sci_625_588
Author(s) : Leonard RJ , Charnet P , Labarca C , Vogelaar NJ , Czyzyk L , Gouin A , Davidson N , Lester HA
Ref : Annals of the New York Academy of Sciences , 625 :588 , 1991
Abstract : Leonard_1991_Ann.N.Y.Acad.Sci_625_588
ESTHER : Leonard_1991_Ann.N.Y.Acad.Sci_625_588
PubMedSearch : Leonard_1991_Ann.N.Y.Acad.Sci_625_588
PubMedID: 2058913

Title : Low molecular weight mRNA encodes a protein that controls serotonin 5-HT1c and acetylcholine M1 receptor sensitivity in Xenopus oocytes - Walter_1991_J.Gen.Physiol_98_399
Author(s) : Walter AE , Hoger JH , Labarca C , Yu L , Davidson N , Lester HA
Ref : Journal of General Physiology , 98 :399 , 1991
Abstract : Walter_1991_J.Gen.Physiol_98_399
ESTHER : Walter_1991_J.Gen.Physiol_98_399
PubMedSearch : Walter_1991_J.Gen.Physiol_98_399
PubMedID: 1940855

Title : Expression of ion channels and receptors in Xenopus oocytes using vaccinia virus - Yang_1991_FASEB.J_5_2209
Author(s) : Yang XC , Karschin A , Labarca C , Elroy-Stein O , Moss B , Davidson N , Lester HA
Ref : FASEB Journal , 5 :2209 , 1991
Abstract : Yang_1991_FASEB.J_5_2209
ESTHER : Yang_1991_FASEB.J_5_2209
PubMedSearch : Yang_1991_FASEB.J_5_2209
PubMedID: 1708738

Title : Single-channel properties of mouse-Torpedo acetylcholine receptor hybrids expressed in Xenopus oocytes - Yu_1991_Brain.Res.Mol.Brain.Res_10_203
Author(s) : Yu L , Leonard RJ , Davidson N , Lester HA
Ref : Brain Research Mol Brain Res , 10 :203 , 1991
Abstract : Yu_1991_Brain.Res.Mol.Brain.Res_10_203
ESTHER : Yu_1991_Brain.Res.Mol.Brain.Res_10_203
PubMedSearch : Yu_1991_Brain.Res.Mol.Brain.Res_10_203
PubMedID: 1715966

Title : Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart - Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694
Author(s) : Karschin A , Ho BY , Labarca C , Elroy-Stein O , Moss B , Davidson N , Lester HA
Ref : Proc Natl Acad Sci U S A , 88 :5694 , 1991
Abstract : Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694
ESTHER : Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694
PubMedSearch : Karschin_1991_Proc.Natl.Acad.Sci.U.S.A_88_5694
PubMedID: 1905814

Title : An open-channel blocker interacts with adjacent turns of alpha-helices in the nicotinic acetylcholine receptor - Charnet_1990_Neuron_4_87
Author(s) : Charnet P , Labarca C , Leonard RJ , Vogelaar NJ , Czyzyk L , Gouin A , Davidson N , Lester HA
Ref : Neuron , 4 :87 , 1990
Abstract : Charnet_1990_Neuron_4_87
ESTHER : Charnet_1990_Neuron_4_87
PubMedSearch : Charnet_1990_Neuron_4_87
PubMedID: 1690017

Title : Functional expression of the yeast alpha-factor receptor in Xenopus oocytes - Yu_1989_J.Biol.Chem_264_20847
Author(s) : Yu L , Blumer KJ , Davidson N , Lester HA , Thorner J
Ref : Journal of Biological Chemistry , 264 :20847 , 1989
Abstract : Yu_1989_J.Biol.Chem_264_20847
ESTHER : Yu_1989_J.Biol.Chem_264_20847
PubMedSearch : Yu_1989_J.Biol.Chem_264_20847
PubMedID: 2556384

Title : Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor - Leonard_1988_Science_242_1578
Author(s) : Leonard RJ , Labarca CG , Charnet P , Davidson N , Lester HA
Ref : Science , 242 :1578 , 1988
Abstract : Leonard_1988_Science_242_1578
ESTHER : Leonard_1988_Science_242_1578
PubMedSearch : Leonard_1988_Science_242_1578
PubMedID: 2462281

Title : Light-flash physiology with synthetic photosensitive compounds -
Author(s) : Gurney AM , Lester HA
Ref : Physiol Rev , 67 :583 , 1987
PubMedID: 3031713

Title : Expression of mouse-Torpedo acetylcholine receptor subunit chimeras and hybrids in Xenopus oocytes - Mayne_1987_Brain.Res_388_191
Author(s) : Mayne KM , Yoshii K , Yu L , Lester HA , Davidson N
Ref : Brain Research , 388 :191 , 1987
Abstract : Mayne_1987_Brain.Res_388_191
ESTHER : Mayne_1987_Brain.Res_388_191
PubMedSearch : Mayne_1987_Brain.Res_388_191
PubMedID: 3676709

Title : Equilibrium properties of mouse-Torpedo acetylcholine receptor hybrids expressed in Xenopus oocytes - Yoshii_1987_J.Gen.Physiol_90_553
Author(s) : Yoshii K , Yu L , Mayne KM , Davidson N , Lester HA
Ref : Journal of General Physiology , 90 :553 , 1987
Abstract : Yoshii_1987_J.Gen.Physiol_90_553
ESTHER : Yoshii_1987_J.Gen.Physiol_90_553
PubMedSearch : Yoshii_1987_J.Gen.Physiol_90_553
PubMedID: 3681261

Title : Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes - Dascal_1986_Science_231_1147
Author(s) : Dascal N , Snutch TP , Lubbert H , Davidson N , Lester HA
Ref : Science , 231 :1147 , 1986
Abstract : Dascal_1986_Science_231_1147
ESTHER : Dascal_1986_Science_231_1147
PubMedSearch : Dascal_1986_Science_231_1147
PubMedID: 2418503

Title : Experiments with photoisomerizable molecules at nicotinic acetylcholine receptors in cells and membrane patches from rat muscle -
Author(s) : Lester HA , Chabala LD , Gurney AM , Sheridan RE
Ref : Soc Gen Physiol Ser , 40 :447 , 1986
PubMedID: 2424099

Title : Dose-response of acetylcholine receptor channels opened by a flash-activated agonist in voltage-clamped rat myoballs - Chabala_1986_J.Physiol_371_407
Author(s) : Chabala LD , Gurney AM , Lester HA
Ref : The Journal of Physiology , 371 :407 , 1986
Abstract : Chabala_1986_J.Physiol_371_407
ESTHER : Chabala_1986_J.Physiol_371_407
PubMedSearch : Chabala_1986_J.Physiol_371_407
PubMedID: 2422352

Title : Activation of acetylcholine receptor channels by covalently bound agonists in cultured rat myoballs - Chabala_1986_J.Physiol_379_83
Author(s) : Chabala LD , Lester HA
Ref : The Journal of Physiology , 379 :83 , 1986
Abstract : Chabala_1986_J.Physiol_379_83
ESTHER : Chabala_1986_J.Physiol_379_83
PubMedSearch : Chabala_1986_J.Physiol_379_83
PubMedID: 2435898

Title : Involvement of a GTP-binding protein in mediation of serotonin and acetylcholine responses in Xenopus oocytes injected with rat brain messenger RNA - Dascal_1986_Brain.Res_387_201
Author(s) : Dascal N , Ifune C , Hopkins R , Snutch TP , Lubbert H , Davidson N , Simon MI , Lester HA
Ref : Brain Research , 387 :201 , 1986
Abstract : Dascal_1986_Brain.Res_387_201
ESTHER : Dascal_1986_Brain.Res_387_201
PubMedSearch : Dascal_1986_Brain.Res_387_201
PubMedID: 2435359

Title : Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes - Dascal_1985_Proc.Natl.Acad.Sci.U.S.A_82_6001
Author(s) : Dascal N , Lotan I , Gillo B , Lester HA , Lass Y
Ref : Proc Natl Acad Sci U S A , 82 :6001 , 1985
Abstract : Dascal_1985_Proc.Natl.Acad.Sci.U.S.A_82_6001
ESTHER : Dascal_1985_Proc.Natl.Acad.Sci.U.S.A_82_6001
PubMedSearch : Dascal_1985_Proc.Natl.Acad.Sci.U.S.A_82_6001
PubMedID: 2994058

Title : Mouse-Torpedo hybrid acetylcholine receptors: functional homology does not equal sequence homology - White_1985_Proc.Natl.Acad.Sci.U.S.A_82_4852
Author(s) : White MM , Mayne KM , Lester HA , Davidson N
Ref : Proc Natl Acad Sci U S A , 82 :4852 , 1985
Abstract : White_1985_Proc.Natl.Acad.Sci.U.S.A_82_4852
ESTHER : White_1985_Proc.Natl.Acad.Sci.U.S.A_82_4852
PubMedSearch : White_1985_Proc.Natl.Acad.Sci.U.S.A_82_4852
PubMedID: 3860826

Title : Photoactivation and dissociation of agonist molecules at the nicotinic acetylcholine receptor in voltage-clamped rat myoballs - Chabala_1985_Biophys.J_48_241
Author(s) : Chabala LD , Gurney AM , Lester HA
Ref : Biophysical Journal , 48 :241 , 1985
Abstract : Chabala_1985_Biophys.J_48_241
ESTHER : Chabala_1985_Biophys.J_48_241
PubMedSearch : Chabala_1985_Biophys.J_48_241
PubMedID: 2413914

Title : Rates and equilibria for a photoisomerizable antagonist at the acetylcholine receptor of Electrophorus electroplaques - Krouse_1985_J.Gen.Physiol_86_235
Author(s) : Krouse ME , Lester HA , Wassermann NH , Erlanger BF
Ref : Journal of General Physiology , 86 :235 , 1985
Abstract : Krouse_1985_J.Gen.Physiol_86_235
ESTHER : Krouse_1985_J.Gen.Physiol_86_235
PubMedSearch : Krouse_1985_J.Gen.Physiol_86_235
PubMedID: 4045419

Title : cis-3,3'-Bis-[alpha-(trimethylammonium)methyl]azobenzene (cis-Bis-Q). Purification and properties at acetylcholine receptors of Electrophorus electroplaques - Nerbonne_1983_Mol.Pharmacol_23_344
Author(s) : Nerbonne JM , Sheridan RE , Chabala LD , Lester HA
Ref : Molecular Pharmacology , 23 :344 , 1983
Abstract : Nerbonne_1983_Mol.Pharmacol_23_344
ESTHER : Nerbonne_1983_Mol.Pharmacol_23_344
PubMedSearch : Nerbonne_1983_Mol.Pharmacol_23_344
PubMedID: 6835200

Title : A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart - Nargeot_1982_J.Gen.Physiol_79_657
Author(s) : Nargeot J , Lester HA , Birdsall NJ , Stockton J , Wassermann NH , Erlanger BF
Ref : Journal of General Physiology , 79 :657 , 1982
Abstract : Nargeot_1982_J.Gen.Physiol_79_657
ESTHER : Nargeot_1982_J.Gen.Physiol_79_657
PubMedSearch : Nargeot_1982_J.Gen.Physiol_79_657
PubMedID: 6978380

Title : ADP-ribosylation of membrane proteins in cholinergic nerve terminals - Lester_1982_J.Neurochem_38_1080
Author(s) : Lester HA , Steer ML , Michaelson DM
Ref : Journal of Neurochemistry , 38 :1080 , 1982
Abstract : Lester_1982_J.Neurochem_38_1080
ESTHER : Lester_1982_J.Neurochem_38_1080
PubMedSearch : Lester_1982_J.Neurochem_38_1080
PubMedID: 7062032

Title : Functional stoichiometry at the nicotinic receptor. The photon cross section for phase 1 corresponds to two bis-Q molecules per channel - Sheridan_1982_J.Gen.Physiol_80_499
Author(s) : Sheridan RE , Lester HA
Ref : Journal of General Physiology , 80 :499 , 1982
Abstract : Sheridan_1982_J.Gen.Physiol_80_499
ESTHER : Sheridan_1982_J.Gen.Physiol_80_499
PubMedSearch : Sheridan_1982_J.Gen.Physiol_80_499
PubMedID: 6292333

Title : Physiological and pharmacological manipulations with light flashes -
Author(s) : Lester HA , Nerbonne JM
Ref : Annu Rev Biophys Bioeng , 11 :151 , 1982
PubMedID: 7049061

Title : A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques - Lester_1980_J.Gen.Physiol_75_207
Author(s) : Lester HA , Krouse ME , Nass MM , Wassermann NH , Erlanger BF
Ref : Journal of General Physiology , 75 :207 , 1980
Abstract : Lester_1980_J.Gen.Physiol_75_207
ESTHER : Lester_1980_J.Gen.Physiol_75_207
PubMedSearch : Lester_1980_J.Gen.Physiol_75_207
PubMedID: 6246192

Title : Electrophysiological experiments with photoisomerizable cholinergic compounds: review and progress report -
Author(s) : Lester HA , Nass MM , Krouse ME , Nerbonne JM , Wassermann NH , Erlanger BF
Ref : Annals of the New York Academy of Sciences , 346 :475 , 1980
PubMedID: 6247953

Title : Numerical reconstruction of the quantal event at nicotinic synapses - Wathey_1979_Biophys.J_27_145
Author(s) : Wathey JC , Nass MM , Lester HA
Ref : Biophysical Journal , 27 :145 , 1979
Abstract : Wathey_1979_Biophys.J_27_145
ESTHER : Wathey_1979_Biophys.J_27_145
PubMedSearch : Wathey_1979_Biophys.J_27_145
PubMedID: 262376

Title : Voltage-dependent and voltage-independent blockade of acetylcholine receptors by local anesthetics in Electrophorus electroplaques -
Author(s) : Koblin DD , Lester HA
Ref : Molecular Pharmacology , 15 :559 , 1979
PubMedID: 492146

Title : The kinetics of tubocurarine action and restricted diffusion within the synaptic cleft - Armstrong_1979_J.Physiol_294_365
Author(s) : Armstrong DL , Lester HA
Ref : The Journal of Physiology , 294 :365 , 1979
Abstract : Armstrong_1979_J.Physiol_294_365
ESTHER : Armstrong_1979_J.Physiol_294_365
PubMedSearch : Armstrong_1979_J.Physiol_294_365
PubMedID: 229214

Title : Analysis of sodium and potassium redistribution during sustained permeability increases at the innervated face of Electrophorus electroplaques - Lester_1978_J.Gen.Physiol_72_847
Author(s) : Lester HA
Ref : Journal of General Physiology , 72 :847 , 1978
Abstract : Lester_1978_J.Gen.Physiol_72_847
ESTHER : Lester_1978_J.Gen.Physiol_72_847
PubMedSearch : Lester_1978_J.Gen.Physiol_72_847
PubMedID: 731201

Title : Role of voltage-sensitive receptors in nicotinic transmission - Lester_1978_Biophys.J_21_181
Author(s) : Lester HA , Koblin DD , Sheridan RE
Ref : Biophysical Journal , 21 :181 , 1978
Abstract : Lester_1978_Biophys.J_21_181
ESTHER : Lester_1978_Biophys.J_21_181
PubMedSearch : Lester_1978_Biophys.J_21_181
PubMedID: 630039

Title : Response of acetylcholine receptors to photoisomerizations of bound agonist molecules - Nass_1978_Biophys.J_24_135
Author(s) : Nass MM , Lester HA , Krouse ME
Ref : Biophysical Journal , 24 :135 , 1978
Abstract : Nass_1978_Biophys.J_24_135
ESTHER : Nass_1978_Biophys.J_24_135
PubMedSearch : Nass_1978_Biophys.J_24_135
PubMedID: 708818

Title : The response to acetylcholine -
Author(s) : Lester HA
Ref : Sci Am , 236 :106 , 1977
PubMedID: 190675

Title : Response of acetylcholine receptors to rapid photochemically produced increases in agonist concentration -
Author(s) : Lester HA , Chang HW
Ref : Nature , 266 :373 , 1977
PubMedID: 859605

Title : Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques: a study of neurally evoked postsynaptic currents and of voltage-jump relaxations - Sheridan_1977_J.Gen.Physiol_70_187
Author(s) : Sheridan RE , Lester HA
Ref : Journal of General Physiology , 70 :187 , 1977
Abstract : Sheridan_1977_J.Gen.Physiol_70_187
ESTHER : Sheridan_1977_J.Gen.Physiol_70_187
PubMedSearch : Sheridan_1977_J.Gen.Physiol_70_187
PubMedID: 894257

Title : Relaxation measurements on the acetylcholine receptor - Sheridan_1975_Proc.Natl.Acad.Sci.U.S.A_72_3496
Author(s) : Sheridan RE , Lester HA
Ref : Proc Natl Acad Sci U S A , 72 :3496 , 1975
Abstract : Sheridan_1975_Proc.Natl.Acad.Sci.U.S.A_72_3496
ESTHER : Sheridan_1975_Proc.Natl.Acad.Sci.U.S.A_72_3496
PubMedSearch : Sheridan_1975_Proc.Natl.Acad.Sci.U.S.A_72_3496
PubMedID: 1059136

Title : Blockade of acetylcholine receptors by cobra toxin: electrophysiological studies -
Author(s) : Lester HA
Ref : Molecular Pharmacology , 8 :623 , 1972
PubMedID: 4344997

Title : Vulnerability of desensitized or curare-treated acetylcholine receptors to irreversible blockade by cobra toxin -
Author(s) : Lester HA
Ref : Molecular Pharmacology , 8 :632 , 1972
PubMedID: 4641003

Title : Postsynaptic action of cobra toxin at the myoneural junction -
Author(s) : Lester HA
Ref : Nature , 227 :727 , 1970
PubMedID: 4317321