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| Title : Potent dual MAGL\/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain - Della Pietra_2023_J.Headache.Pain_24_38 |
| Author(s) : Della Pietra A , Krivoshein G , Ivanov K , Giniatullina R , Jyrkkanen HK , Leinonen V , Lehtonen M , van den Maagdenberg A , Savinainen J , Giniatullin R |
| Ref : J Headache Pain , 24 :38 , 2023 |
| Abstract : Della Pietra_2023_J.Headache.Pain_24_38 |
| ESTHER : Della Pietra_2023_J.Headache.Pain_24_38 |
| PubMedSearch : Della Pietra_2023_J.Headache.Pain_24_38 |
| PubMedID: 37038131 |
| Gene_locus related to this paper: human-MGLL |
| Title : In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)m ethanone (JJKK-048) - Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| Author(s) : Aaltonen N , Kedzierska E , Orzelska-Gorka J , Lehtonen M , Navia-Paldanius D , Jakupovic H , Savinainen JR , Nevalainen T , Laitinen JT , Parkkari T , Gynther M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 359 :62 , 2016 |
| Abstract : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| ESTHER : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| PubMedSearch : Aaltonen_2016_J.Pharmacol.Exp.Ther_359_62 |
| PubMedID: 27451409 |
| Title : Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi\/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase - Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| Author(s) : Navia-Paldanius D , Aaltonen N , Lehtonen M , Savinainen JR , Taschler U , Radner FP , Zimmermann R , Laitinen JT |
| Ref : Eur J Pharm Sci , 77 :180 , 2015 |
| Abstract : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| ESTHER : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| PubMedSearch : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| PubMedID: 26070239 |
| Title : Discovery of Triterpenoids as Reversible Inhibitors of alpha\/beta-hydrolase Domain Containing 12 (ABHD12) - Parkkari_2014_PLoS.One_9_e98286 |
| Author(s) : Parkkari T , Haavikko R , Laitinen T , Navia-Paldanius D , Rytilahti R , Vaara M , Lehtonen M , Alakurtti S , Yli-Kauhaluoma J , Nevalainen T , Savinainen JR , Laitinen JT |
| Ref : PLoS ONE , 9 :e98286 , 2014 |
| Abstract : Parkkari_2014_PLoS.One_9_e98286 |
| ESTHER : Parkkari_2014_PLoS.One_9_e98286 |
| PubMedSearch : Parkkari_2014_PLoS.One_9_e98286 |
| PubMedID: 24879289 |
| Gene_locus related to this paper: human-ABHD12 |
| Title : Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL) - Savinainen_2014_Mol.Pharmacol_86_522 |
| Author(s) : Savinainen JR , Kansanen E , Pantsar T , Navia-Paldanius D , Parkkari T , Lehtonen M , Laitinen T , Nevalainen T , Poso A , Levonen AL , Laitinen JT |
| Ref : Molecular Pharmacology , 86 :522 , 2014 |
| Abstract : Savinainen_2014_Mol.Pharmacol_86_522 |
| ESTHER : Savinainen_2014_Mol.Pharmacol_86_522 |
| PubMedSearch : Savinainen_2014_Mol.Pharmacol_86_522 |
| PubMedID: 25140003 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Brain regional cannabinoid CB1 receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice - Aaltonen_2014_Eur.J.Pharm.Sci_51_87 |
| Author(s) : Aaltonen N , Riera Ribas C , Lehtonen M , Savinainen JR , Laitinen JT |
| Ref : Eur J Pharm Sci , 51 :87 , 2014 |
| Abstract : Aaltonen_2014_Eur.J.Pharm.Sci_51_87 |
| ESTHER : Aaltonen_2014_Eur.J.Pharm.Sci_51_87 |
| PubMedSearch : Aaltonen_2014_Eur.J.Pharm.Sci_51_87 |
| PubMedID: 24012970 |
| Title : Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase - Aaltonen_2013_Chem.Biol_20_379 |
| Author(s) : Aaltonen N , Savinainen JR , Ribas CR , Ronkko J , Kuusisto A , Korhonen J , Navia-Paldanius D , Hayrinen J , Takabe P , Kasnanen H , Pantsar T , Laitinen T , Lehtonen M , Pasonen-Seppanen S , Poso A , Nevalainen T , Laitinen JT |
| Ref : Chemical Biology , 20 :379 , 2013 |
| Abstract : Aaltonen_2013_Chem.Biol_20_379 |
| ESTHER : Aaltonen_2013_Chem.Biol_20_379 |
| PubMedSearch : Aaltonen_2013_Chem.Biol_20_379 |
| PubMedID: 23521796 |
| Gene_locus related to this paper: human-MGLL |
| Title : Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats - Ihalainen_2011_Neuropharmacol_61_891 |
| Author(s) : Ihalainen J , Sarajarvi T , Rasmusson D , Kemppainen S , Keski-Rahkonen P , Lehtonen M , Banerjee PK , Semba K , Tanila H |
| Ref : Neuropharmacology , 61 :891 , 2011 |
| Abstract : Ihalainen_2011_Neuropharmacol_61_891 |
| ESTHER : Ihalainen_2011_Neuropharmacol_61_891 |
| PubMedSearch : Ihalainen_2011_Neuropharmacol_61_891 |
| PubMedID: 21704049 |