Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
| Title : An Antibacterial beta-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis - Lehmann_2018_Angew.Chem.Int.Ed.Engl_57_348 |
| Author(s) : Lehmann J , Cheng TY , Aggarwal A , Park AS , Zeiler E , Raju RM , Akopian T , Kandror O , Sacchettini JC , Moody DB , Rubin EJ , Sieber SA |
| Ref : Angew Chem Int Ed Engl , 57 :348 , 2018 |
| Abstract : Lehmann_2018_Angew.Chem.Int.Ed.Engl_57_348 |
| ESTHER : Lehmann_2018_Angew.Chem.Int.Ed.Engl_57_348 |
| PubMedSearch : Lehmann_2018_Angew.Chem.Int.Ed.Engl_57_348 |
| PubMedID: 29067779 |
| Title : Human lysosomal acid lipase inhibitor lalistat impairs Mycobacterium tuberculosis growth by targeting bacterial hydrolases - Lehmann_2016_Medchemcomm_7_1797 |
| Author(s) : Lehmann J , Vomacka J , Esser K , Nodwell M , Kolbe K , Ramer P , Protzer U , Reiling N , Sieber SA |
| Ref : Medchemcomm , 7 :1797 , 2016 |
| Abstract : Lehmann_2016_Medchemcomm_7_1797 |
| ESTHER : Lehmann_2016_Medchemcomm_7_1797 |
| PubMedSearch : Lehmann_2016_Medchemcomm_7_1797 |
| PubMedID: |
| Gene_locus related to this paper: myctu-cutas1 , myctu-lipG , myctu-RV0045C , myctu-rv0183 , myctu-RV0293C , myctu-RV0840C , myctu-Rv1191 , myctu-RV1192 , myctu-Rv1399c , myctu-Rv1400c , myctu-Rv1426c , myctu-Rv2045c , myctu-Rv2284 , myctu-Rv2970c , myctu-Rv3084 , myctu-YR15 , larcr-a0a0f7ir14 |
| Title : Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders - Otto_2015_J.Med.Chem_58_6710 |
| Author(s) : Otto R , Penzis R , Gaube F , Adolph O , Fohr KJ , Warncke P , Robaa D , Appenroth D , Fleck C , Enzensperger C , Lehmann J , Winckler T |
| Ref : Journal of Medicinal Chemistry , 58 :6710 , 2015 |
| Abstract : Otto_2015_J.Med.Chem_58_6710 |
| ESTHER : Otto_2015_J.Med.Chem_58_6710 |
| PubMedSearch : Otto_2015_J.Med.Chem_58_6710 |
| PubMedID: 26278660 |
| Title : Beta and gamma carboline derivatives as potential anti-Alzheimer agents: A comparison - Otto_2014_Eur.J.Med.Chem_87C_63 |
| Author(s) : Otto R , Penzis R , Gaube F , Winckler T , Appenroth D , Fleck C , Trankle C , Lehmann J , Enzensperger C |
| Ref : Eur Journal of Medicinal Chemistry , 87C :63 , 2014 |
| Abstract : Otto_2014_Eur.J.Med.Chem_87C_63 |
| ESTHER : Otto_2014_Eur.J.Med.Chem_87C_63 |
| PubMedSearch : Otto_2014_Eur.J.Med.Chem_87C_63 |
| PubMedID: 25240096 |
| Title : NO-donating tacrine derivatives as potential butyrylcholinesterase inhibitors with vasorelaxation activity - Chen_2013_Bioorg.Med.Chem.Lett_23_3162 |
| Author(s) : Chen Y , Sun J , Huang Z , Liao H , Peng S , Lehmann J , Zhang Y |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3162 , 2013 |
| Abstract : Chen_2013_Bioorg.Med.Chem.Lett_23_3162 |
| ESTHER : Chen_2013_Bioorg.Med.Chem.Lett_23_3162 |
| PubMedSearch : Chen_2013_Bioorg.Med.Chem.Lett_23_3162 |
| PubMedID: 23639542 |
| Title : Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease - Chen_2013_Arch.Pharm.(Weinheim)_346_865 |
| Author(s) : Chen Y , Sun J , Peng S , Liao H , Zhang Y , Lehmann J |
| Ref : Arch Pharm (Weinheim) , 346 :865 , 2013 |
| Abstract : Chen_2013_Arch.Pharm.(Weinheim)_346_865 |
| ESTHER : Chen_2013_Arch.Pharm.(Weinheim)_346_865 |
| PubMedSearch : Chen_2013_Arch.Pharm.(Weinheim)_346_865 |
| PubMedID: 24203864 |
| Title : Discovery of a novel acetylcholinesterase inhibitor by structure-based virtual screening techniques - Chen_2012_Bioorg.Med.Chem.Lett_22_3181 |
| Author(s) : Chen Y , Fang L , Peng S , Liao H , Lehmann J , Zhang Y |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :3181 , 2012 |
| Abstract : Chen_2012_Bioorg.Med.Chem.Lett_22_3181 |
| ESTHER : Chen_2012_Bioorg.Med.Chem.Lett_22_3181 |
| PubMedSearch : Chen_2012_Bioorg.Med.Chem.Lett_22_3181 |
| PubMedID: 22472693 |
| Title : Tacrine-ferulic acid-nitric oxide (NO) donor trihybrids as potent, multifunctional acetyl- and butyrylcholinesterase inhibitors - Chen_2012_J.Med.Chem_55_4309 |
| Author(s) : Chen Y , Sun J , Fang L , Liu M , Peng S , Liao H , Lehmann J , Zhang Y |
| Ref : Journal of Medicinal Chemistry , 55 :4309 , 2012 |
| Abstract : Chen_2012_J.Med.Chem_55_4309 |
| ESTHER : Chen_2012_J.Med.Chem_55_4309 |
| PubMedSearch : Chen_2012_J.Med.Chem_55_4309 |
| PubMedID: 22512543 |
| Title : Bivalent 5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]isoquinolines and -isoquinolinium salts: novel heterocyclic templates for butyrylcholinesterase inhibitors - Schulze_2010_Bioorg.Med.Chem.Lett_20_2946 |
| Author(s) : Schulze M , Siol O , Decker M , Lehmann J |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :2946 , 2010 |
| Abstract : Schulze_2010_Bioorg.Med.Chem.Lett_20_2946 |
| ESTHER : Schulze_2010_Bioorg.Med.Chem.Lett_20_2946 |
| PubMedSearch : Schulze_2010_Bioorg.Med.Chem.Lett_20_2946 |
| PubMedID: 20350808 |
| Title : Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents - Rook_2010_J.Med.Chem_53_3611 |
| Author(s) : Rook Y , Schmidtke KU , Gaube F , Schepmann D , Wunsch B , Heilmann J , Lehmann J , Winckler T |
| Ref : Journal of Medicinal Chemistry , 53 :3611 , 2010 |
| Abstract : Rook_2010_J.Med.Chem_53_3611 |
| ESTHER : Rook_2010_J.Med.Chem_53_3611 |
| PubMedSearch : Rook_2010_J.Med.Chem_53_3611 |
| PubMedID: 20361801 |
| Title : NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity - Fang_2008_J.Med.Chem_51_7666 |
| Author(s) : Fang L , Appenroth D , Decker M , Kiehntopf M , Lupp A , Peng S , Fleck C , Zhang Y , Lehmann J |
| Ref : Journal of Medicinal Chemistry , 51 :7666 , 2008 |
| Abstract : Fang_2008_J.Med.Chem_51_7666 |
| ESTHER : Fang_2008_J.Med.Chem_51_7666 |
| PubMedSearch : Fang_2008_J.Med.Chem_51_7666 |
| PubMedID: 19053746 |
| Title : Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates - Fang_2008_J.Med.Chem_51_713 |
| Author(s) : Fang L , Appenroth D , Decker M , Kiehntopf M , Roegler C , Deufel T , Fleck C , Peng S , Zhang Y , Lehmann J |
| Ref : Journal of Medicinal Chemistry , 51 :713 , 2008 |
| Abstract : Fang_2008_J.Med.Chem_51_713 |
| ESTHER : Fang_2008_J.Med.Chem_51_713 |
| PubMedSearch : Fang_2008_J.Med.Chem_51_713 |
| PubMedID: 18232655 |
| Title : Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates - Fang_2008_Bioorg.Med.Chem.Lett_18_2905 |
| Author(s) : Fang L , Kraus B , Lehmann J , Heilmann J , Zhang Y , Decker M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :2905 , 2008 |
| Abstract : Fang_2008_Bioorg.Med.Chem.Lett_18_2905 |
| ESTHER : Fang_2008_Bioorg.Med.Chem.Lett_18_2905 |
| PubMedSearch : Fang_2008_Bioorg.Med.Chem.Lett_18_2905 |
| PubMedID: 18406135 |
| Title : A new way of data interpretation for cognition tests in rats used to characterise six choline esterase inhibitors with heterocyclic nitrogen bridgehead structure. Application in Alzheimer therapy - Fleck_2008_Arzneimittelforschung_58_543 |
| Author(s) : Fleck C , Appenroth D , Decker M , Lehmann J |
| Ref : Arzneimittelforschung , 58 :543 , 2008 |
| Abstract : Fleck_2008_Arzneimittelforschung_58_543 |
| ESTHER : Fleck_2008_Arzneimittelforschung_58_543 |
| PubMedSearch : Fleck_2008_Arzneimittelforschung_58_543 |
| PubMedID: 19137904 |
| Title : 6-Hydroxy- and 6-methoxy-beta-carbolines as acetyl- and butyrylcholinesterase inhibitors - Schott_2006_Bioorg.Med.Chem.Lett_16_5840 |
| Author(s) : Schott Y , Decker M , Rommelspacher H , Lehmann J |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5840 , 2006 |
| Abstract : Schott_2006_Bioorg.Med.Chem.Lett_16_5840 |
| ESTHER : Schott_2006_Bioorg.Med.Chem.Lett_16_5840 |
| PubMedSearch : Schott_2006_Bioorg.Med.Chem.Lett_16_5840 |
| PubMedID: 16945529 |
| Title : Novel tricyclic quinazolinimines and related tetracyclic nitrogen bridgehead compounds as cholinesterase inhibitors with selectivity towards butyrylcholinesterase - Decker_2006_Bioorg.Med.Chem_14_1966 |
| Author(s) : Decker M , Krauth F , Lehmann J |
| Ref : Bioorganic & Medicinal Chemistry , 14 :1966 , 2006 |
| Abstract : Decker_2006_Bioorg.Med.Chem_14_1966 |
| ESTHER : Decker_2006_Bioorg.Med.Chem_14_1966 |
| PubMedSearch : Decker_2006_Bioorg.Med.Chem_14_1966 |
| PubMedID: 16289855 |
| Title : Functional screening of G protein-coupled receptors by measuring intracellular calcium with a fluorescence microplate reader - Kassack_2002_J.Biomol.Screen_7_233 |
| Author(s) : Kassack MU , Hofgen B , Lehmann J , Eckstein N , Quillan JM , Sadee W |
| Ref : J Biomol Screen , 7 :233 , 2002 |
| Abstract : Kassack_2002_J.Biomol.Screen_7_233 |
| ESTHER : Kassack_2002_J.Biomol.Screen_7_233 |
| PubMedSearch : Kassack_2002_J.Biomol.Screen_7_233 |
| PubMedID: 12097186 |
| Title : The autoinhibitory feedback control of acetylcholine release in human neocortex tissue - Feuerstein_1992_Brain.Res_572_64 |
| Author(s) : Feuerstein TJ , Lehmann J , Sauermann W , van Velthoven V , Jackisch R |
| Ref : Brain Research , 572 :64 , 1992 |
| Abstract : Feuerstein_1992_Brain.Res_572_64 |
| ESTHER : Feuerstein_1992_Brain.Res_572_64 |
| PubMedSearch : Feuerstein_1992_Brain.Res_572_64 |
| PubMedID: 1611539 |
| Title : Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons - Lehmann_1988_J.Neurochem_51_1765 |
| Author(s) : Lehmann J , Tsai C , Wood PL |
| Ref : Journal of Neurochemistry , 51 :1765 , 1988 |
| Abstract : Lehmann_1988_J.Neurochem_51_1765 |
| ESTHER : Lehmann_1988_J.Neurochem_51_1765 |
| PubMedSearch : Lehmann_1988_J.Neurochem_51_1765 |
| PubMedID: 2846784 |
| Title : Cortical Cholinergic Innervation: Distribution and Source in Monkeys - |
| Author(s) : Struble RG , Lehmann J , Mitchell SJ , Cork LC , Coyle JT , Price DL , DeLong MR , Antuono PG |
| Ref : Advances in Behavioral Biology , 30 :23 , 1986 |
| PubMedID: |
| Title : Basal forebrain neurons provide major cholinergic innervation of primate neocortex - Struble_1986_Neurosci.Lett_66_215 |
| Author(s) : Struble RG , Lehmann J , Mitchell SJ , McKinney M , Price DL , Coyle JT , DeLong MR |
| Ref : Neuroscience Letters , 66 :215 , 1986 |
| Abstract : Struble_1986_Neurosci.Lett_66_215 |
| ESTHER : Struble_1986_Neurosci.Lett_66_215 |
| PubMedSearch : Struble_1986_Neurosci.Lett_66_215 |
| PubMedID: 2425286 |
| Title : Presynaptic nicotinic cholinergic receptors labeled by [3H]acetylcholine on catecholamine and serotonin axons in brain - Schwartz_1984_J.Neurochem_42_1495 |
| Author(s) : Schwartz RD , Lehmann J , Kellar KJ |
| Ref : Journal of Neurochemistry , 42 :1495 , 1984 |
| Abstract : Schwartz_1984_J.Neurochem_42_1495 |
| ESTHER : Schwartz_1984_J.Neurochem_42_1495 |
| PubMedSearch : Schwartz_1984_J.Neurochem_42_1495 |
| PubMedID: 6707650 |
| Title : Regional heterogeneity of choline acetyltransferase activity in primate neocortex - Lehmann_1984_Brain.Res_322_361 |
| Author(s) : Lehmann J , Struble RG , Antuono PG , Coyle JT , Cork LC , Price DL |
| Ref : Brain Research , 322 :361 , 1984 |
| Abstract : Lehmann_1984_Brain.Res_322_361 |
| ESTHER : Lehmann_1984_Brain.Res_322_361 |
| PubMedSearch : Lehmann_1984_Brain.Res_322_361 |
| PubMedID: 6509325 |
| Title : Characterization of the excitatory amino acid receptor-mediated release of [3H]acetylcholine from rat striatal slices - Lehmann_1982_Brain.Res_252_77 |
| Author(s) : Lehmann J , Scatton B |
| Ref : Brain Research , 252 :77 , 1982 |
| Abstract : Lehmann_1982_Brain.Res_252_77 |
| ESTHER : Lehmann_1982_Brain.Res_252_77 |
| PubMedSearch : Lehmann_1982_Brain.Res_252_77 |
| PubMedID: 6129033 |
| Title : Anatomical Organization of Some Cholinergic Systems in the Mammalian Forebrain - |
| Author(s) : Fibiger HC , Lehmann J |
| Ref : Advances in Behavioral Biology , 25 :663\ , 1981 |
| PubMedID: |
| Title : The localization of acetylcholinesterase in the corpus striatum and substantia nigra of the rat following kainic acid lesion of the corpus striatum: a biochemical and histochemical study - |
| Author(s) : Lehmann J , Fibiger HC , Butcher LL |
| Ref : Neuroscience , 4 :217 , 1979 |
| PubMedID: 424071 |