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Title : Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK\/Akt\/mTOR - Verbrugge_2016_Oncotarget_7_5240 |
Author(s) : Verbrugge SE , Al M , Assaraf YG , Kammerer S , Chandrupatla DM , Honeywell R , Musters RP , Giovannetti E , O'Toole T , Scheffer GL , Krige D , de Gruijl TD , Niessen HW , Lems WF , Kramer PA , Scheper RJ , Cloos J , Ossenkoppele GJ , Peters GJ , Jansen G |
Ref : Oncotarget , 7 :5240 , 2016 |
Abstract : Verbrugge_2016_Oncotarget_7_5240 |
ESTHER : Verbrugge_2016_Oncotarget_7_5240 |
PubMedSearch : Verbrugge_2016_Oncotarget_7_5240 |
PubMedID: 26496029 |
Title : The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria - Skinner-Adams_2012_Antimicrob.Agents.Chemother_56_3244 |
Author(s) : Skinner-Adams TS , Peatey CL , Anderson K , Trenholme KR , Krige D , Brown CL , Stack C , Nsangou DM , Mathews RT , Thivierge K , Dalton JP , Gardiner DL |
Ref : Antimicrobial Agents & Chemotherapy , 56 :3244 , 2012 |
Abstract : Skinner-Adams_2012_Antimicrob.Agents.Chemother_56_3244 |
ESTHER : Skinner-Adams_2012_Antimicrob.Agents.Chemother_56_3244 |
PubMedSearch : Skinner-Adams_2012_Antimicrob.Agents.Chemother_56_3244 |
PubMedID: 22450967 |