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| Title : Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625\/WYE-103914) - Ghiron_2010_J.Med.Chem_53_4379 |
| Author(s) : Ghiron C , Haydar SN , Aschmies S , Bothmann H , Castaldo C , Cocconcelli G , Comery TA , Di L , Dunlop J , Lock T , Kramer A , Kowal D , Jow F , Grauer S , Harrison B , La Rosa S , Maccari L , Marquis KL , Micco I , Nencini A , Quinn J , Robichaud AJ , Roncarati R , Scali C , Terstappen GC , Turlizzi E , Valacchi M , Varrone M , Zanaletti R , Zanelli U |
| Ref : Journal of Medicinal Chemistry , 53 :4379 , 2010 |
| Abstract : Ghiron_2010_J.Med.Chem_53_4379 |
| ESTHER : Ghiron_2010_J.Med.Chem_53_4379 |
| PubMedSearch : Ghiron_2010_J.Med.Chem_53_4379 |
| PubMedID: 20465311 |
| Title : Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system - Chanda_2010_Mol.Pharmacol_78_996 |
| Author(s) : Chanda PK , Gao Y , Mark L , Btesh J , Strassle BW , Lu P , Piesla MJ , Zhang MY , Bingham B , Uveges A , Kowal D , Garbe D , Kouranova EV , Ring RH , Bates B , Pangalos MN , Kennedy JD , Whiteside GT , Samad TA |
| Ref : Molecular Pharmacology , 78 :996 , 2010 |
| Abstract : Chanda_2010_Mol.Pharmacol_78_996 |
| ESTHER : Chanda_2010_Mol.Pharmacol_78_996 |
| PubMedSearch : Chanda_2010_Mol.Pharmacol_78_996 |
| PubMedID: 20855465 |
| Title : Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders - Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| Author(s) : Roncarati R , Scali C , Comery TA , Grauer SM , Aschmi S , Bothmann H , Jow B , Kowal D , Gianfriddo M , Kelley C , Zanelli U , Ghiron C , Haydar S , Dunlop J , Terstappen GC |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 329 :459 , 2009 |
| Abstract : Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| ESTHER : Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| PubMedSearch : Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| PubMedID: 19223665 |
| Title : Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B\/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide) - Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
| Author(s) : Dunlop J , Lock T , Jow B , Sitzia F , Grauer S , Jow F , Kramer A , Bowlby MR , Randall A , Kowal D , Gilbert A , Comery TA , Larocque J , Soloveva V , Brown J , Roncarati R |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 328 :766 , 2009 |
| Abstract : Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
| ESTHER : Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
| PubMedSearch : Dunlop_2009_J.Pharmacol.Exp.Ther_328_766 |
| PubMedID: 19050173 |
| Title : Poster: In vitro pharmacological characterization and pro-cognitive effects of the selective alpha-7 nicotinic agonist WYE-103914 - |
| Author(s) : Dunlop J , Comery TA , Lock T , Kramer A , Kowal D , Yeola S , Jow F , Aschmies S , Lin Q , Beyer CE , Brennan J , Kelley C , Roncarati R , Scali C , Haydar S , Ghiron C , Marquis KL , Harrison B , Robichaud A , Terstappen GC |
| Ref : Biochemical Pharmacology , 78 :911 , 2009 |
| PubMedID: |
| Title : In vitro screening strategies for nicotinic receptor ligands - Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| Author(s) : Dunlop J , Roncarati R , Jow B , Bothmann H , Lock T , Kowal D , Bowlby M , Terstappen GC |
| Ref : Biochemical Pharmacology , 74 :1172 , 2007 |
| Abstract : Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| ESTHER : Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| PubMedSearch : Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| PubMedID: 17706607 |