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Author Report for: Kovalevsky A

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Kovalevsky Andrey
Oak Ridge National Laboratory, Oak Ridge, Tennessee
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    Title: Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering
    Gerlits O, Fajer M, Cheng X, Blumenthal DK, Radic Z, Kovalevsky A
    Ref: Structure, :, 2022 : PubMed


    Title: Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects
    Blumenthal DK, Cheng X, Fajer M, Ho KY, Rohrer J, Gerlits O, Taylor P, Juneja P, Kovalevsky A, Radic Z
    Ref: Journal of Biological Chemistry, :101007, 2021 : PubMed


    Title: Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure
    Gerlits O, Blakeley MP, Keen DA, Radic Z, Kovalevsky A
    Ref: Current Research in Structural Biology, 3:206, 2021 : PubMed


    Title: Characterization and structural analysis of a thermophilic GH11 xylanase from compost metatranscriptome
    Yi Y, Xu S, Kovalevsky A, Zhang X, Liu D, Wan Q
    Ref: Applied Microbiology & Biotechnology, 105:7757, 2021 : PubMed


    Title: Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
    Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radic Z
    Ref: Journal of Biological Chemistry, 295:4079, 2020 : PubMed


    Title: A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies
    Gerlits O, Ho KY, Cheng X, Blumenthal D, Taylor P, Kovalevsky A, Radic Z
    Ref: Chemico-Biological Interactions, :, 2019 : PubMed


    Title: Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase
    Gerlits O, Kong X, Cheng X, Wymore T, Blumenthal DK, Taylor P, Radic Z, Kovalevsky A
    Ref: Journal of Biological Chemistry, 294:10607, 2019 : PubMed


    Title: IMAGINE: neutrons reveal enzyme chemistry
    Schroder GC, O'Dell WB, Myles DAA, Kovalevsky A, Meilleur F
    Ref: Acta Crystallographica D Struct Biol, 74:778, 2018 : PubMed


    Title: Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning
    Kovalevsky A, Blumenthal DK, Cheng X, Taylor P, Radic Z
    Ref: Annals of the New York Academy of Sciences, 1378:41, 2016 : PubMed


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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