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Title : Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs - Xiao_2013_Biochem.Pharmacol_85_439 |
Author(s) : Xiao D , Shi D , Yang D , Barthel B , Koch TH , Yan B |
Ref : Biochemical Pharmacology , 85 :439 , 2013 |
Abstract : Xiao_2013_Biochem.Pharmacol_85_439 |
ESTHER : Xiao_2013_Biochem.Pharmacol_85_439 |
PubMedSearch : Xiao_2013_Biochem.Pharmacol_85_439 |
PubMedID: 23228697 |
Gene_locus related to this paper: human-CES2 |
Title : Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug - Barthel_2008_J.Med.Chem_51_298 |
Author(s) : Barthel BL , Torres RC , Hyatt JL , Edwards CC , Hatfield MJ , Potter PM , Koch TH |
Ref : Journal of Medicinal Chemistry , 51 :298 , 2008 |
Abstract : Barthel_2008_J.Med.Chem_51_298 |
ESTHER : Barthel_2008_J.Med.Chem_51_298 |
PubMedSearch : Barthel_2008_J.Med.Chem_51_298 |
PubMedID: 18173233 |