Full name : Klein Jochen
First name : Jochen
Mail : Department of Pharmacology, Goethe University of Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt
Zip Code :
City :
Country : Germany
Email : Klein@em.uni-frankfurt.de
Phone :
Fax :
Website :
Directory :
| Title : Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice - Kondak_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Kondak C , Leith M , Baddeley TC , Santos RX , Harrington CR , Wischik CM , Riedel G , Klein J |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : Kondak_2023_Int.J.Mol.Sci_24_ |
| ESTHER : Kondak_2023_Int.J.Mol.Sci_24_ |
| PubMedSearch : Kondak_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37445987 |
| Title : Central cholinergic function and metabolic changes in streptozotocin-induced rat brain injury - Yuliani_2021_J.Neurochem_158_1307 |
| Author(s) : Yuliani T , Lobentanzer S , Klein J |
| Ref : Journal of Neurochemistry , 158 :1307 , 2021 |
| Abstract : Yuliani_2021_J.Neurochem_158_1307 |
| ESTHER : Yuliani_2021_J.Neurochem_158_1307 |
| PubMedSearch : Yuliani_2021_J.Neurochem_158_1307 |
| PubMedID: 33448390 |
| Title : Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine - Kondak_2021_J.Neurochem__ |
| Author(s) : Kondak C , Riedel G , Harrington CR , Wischik CM , Klein J |
| Ref : Journal of Neurochemistry , : , 2021 |
| Abstract : Kondak_2021_J.Neurochem__ |
| ESTHER : Kondak_2021_J.Neurochem__ |
| PubMedSearch : Kondak_2021_J.Neurochem__ |
| PubMedID: 34855998 |
| Title : Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade - Winek_2020_Proc.Natl.Acad.Sci.U.S.A_117_32606 |
| Author(s) : Winek K , Lobentanzer S , Nadorp B , Dubnov S , Dames C , Jagdmann S , Moshitzky G , Hotter B , Meisel C , Greenberg DS , Shifman S , Klein J , Shenhar-Tsarfaty S , Meisel A , Soreq H |
| Ref : Proc Natl Acad Sci U S A , 117 :32606 , 2020 |
| Abstract : Winek_2020_Proc.Natl.Acad.Sci.U.S.A_117_32606 |
| ESTHER : Winek_2020_Proc.Natl.Acad.Sci.U.S.A_117_32606 |
| PubMedSearch : Winek_2020_Proc.Natl.Acad.Sci.U.S.A_117_32606 |
| PubMedID: 33288717 |
| Title : Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model - Riedel_2020_Curr.Alzheimer.Res__ |
| Author(s) : Riedel G , Klein J , Niewiadomska G , Kondak C , Schwab K , Lauer D , Magbagbeolu M , Steczkowska M , Zadrozny M , Wydrych M , Cranston A , Melis V , Santos RX , Theuring F , Harrington CR , Wischik CM |
| Ref : Curr Alzheimer Res , : , 2020 |
| Abstract : Riedel_2020_Curr.Alzheimer.Res__ |
| ESTHER : Riedel_2020_Curr.Alzheimer.Res__ |
| PubMedSearch : Riedel_2020_Curr.Alzheimer.Res__ |
| PubMedID: 32091331 |
| Title : Impaired hippocampal and thalamic acetylcholine release in P301L tau-transgenic mice - Stein_2019_Brain.Res.Bull_152_134 |
| Author(s) : Stein C , Koch K , Hopfeld J , Lobentanzer S , Lau H , Klein J |
| Ref : Brain Research Bulletin , 152 :134 , 2019 |
| Abstract : Stein_2019_Brain.Res.Bull_152_134 |
| ESTHER : Stein_2019_Brain.Res.Bull_152_134 |
| PubMedSearch : Stein_2019_Brain.Res.Bull_152_134 |
| PubMedID: 31323279 |
| Title : Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1beta via CD36 and Nicotinic Acetylcholine Receptors - Siebers_2018_Front.Immunol_9_877 |
| Author(s) : Siebers K , Fink B , Zakrzewicz A , Agne A , Richter K , Konzok S , Hecker A , Zukunft S , Kullmar M , Klein J , McIntosh JM , Timm T , Sewald K , Padberg W , Aggarwal N , Chamulitrat W , Santoso S , Xia W , Janciauskiene S , Grau V |
| Ref : Front Immunol , 9 :877 , 2018 |
| Abstract : Siebers_2018_Front.Immunol_9_877 |
| ESTHER : Siebers_2018_Front.Immunol_9_877 |
| PubMedSearch : Siebers_2018_Front.Immunol_9_877 |
| PubMedID: 29922281 |
| Title : Cholinergic activation of the murine trachealis muscle via non-vesicular acetylcholine release involving low-affinity choline transporters - Nassenstein_2015_Int.Immunopharmacol_29(1)_173 |
| Author(s) : Nassenstein C , Wiegand S , Lips KS , Li G , Klein J , Kummer W |
| Ref : Int Immunopharmacol , 29 :173 , 2015 |
| Abstract : Nassenstein_2015_Int.Immunopharmacol_29(1)_173 |
| ESTHER : Nassenstein_2015_Int.Immunopharmacol_29(1)_173 |
| PubMedSearch : Nassenstein_2015_Int.Immunopharmacol_29(1)_173 |
| PubMedID: 26278668 |
| Title : Effects of Ginkgo biloba Extract EGb 761, Donepezil and their Combination on Central Cholinergic Function in Aged Rats - Stein_2015_J.Pharm.Pharm.Sci_18_634 |
| Author(s) : Stein C , Hopfeld J , Lau H , Klein J |
| Ref : J Pharm Pharm Sci , 18 :634 , 2015 |
| Abstract : Stein_2015_J.Pharm.Pharm.Sci_18_634 |
| ESTHER : Stein_2015_J.Pharm.Pharm.Sci_18_634 |
| PubMedSearch : Stein_2015_J.Pharm.Pharm.Sci_18_634 |
| PubMedID: 26626253 |
| Title : Dysfunctional Presynaptic M2 Receptors in the Presence of Chronically High Acetylcholine Levels: Data from the PRiMA Knockout Mouse - Mohr_2015_PLoS.One_10_e0141136 |
| Author(s) : Mohr F , Krejci E , Zimmermann M , Klein J |
| Ref : PLoS ONE , 10 :e0141136 , 2015 |
| Abstract : Mohr_2015_PLoS.One_10_e0141136 |
| ESTHER : Mohr_2015_PLoS.One_10_e0141136 |
| PubMedSearch : Mohr_2015_PLoS.One_10_e0141136 |
| PubMedID: 26506622 |
| Title : Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes - Deckmann_2014_Proc.Natl.Acad.Sci.U.S.A_111_8287 |
| Author(s) : Deckmann K , Filipski K , Krasteva-Christ G , Fronius M , Althaus M , Rafiq A , Papadakis T , Renno L , Jurastow I , Wessels L , Wolff M , Schutz B , Weihe E , Chubanov V , Gudermann T , Klein J , Bschleipfer T , Kummer W |
| Ref : Proc Natl Acad Sci U S A , 111 :8287 , 2014 |
| Abstract : Deckmann_2014_Proc.Natl.Acad.Sci.U.S.A_111_8287 |
| ESTHER : Deckmann_2014_Proc.Natl.Acad.Sci.U.S.A_111_8287 |
| PubMedSearch : Deckmann_2014_Proc.Natl.Acad.Sci.U.S.A_111_8287 |
| PubMedID: 24843119 |
| Title : Choline acetyltransferase and organic cation transporters are responsible for synthesis and propionate-induced release of acetylcholine in colon epithelium - Bader_2014_Eur.J.Pharmacol_733_23 |
| Author(s) : Bader S , Klein J , Diener M |
| Ref : European Journal of Pharmacology , 733 :23 , 2014 |
| Abstract : Bader_2014_Eur.J.Pharmacol_733_23 |
| ESTHER : Bader_2014_Eur.J.Pharmacol_733_23 |
| PubMedSearch : Bader_2014_Eur.J.Pharmacol_733_23 |
| PubMedID: 24698650 |
| Title : Pathophysiological amyloid concentrations induce sustained upregulation of readthrough acetylcholinesterase mediating anti-apoptotic effects - Li_2013_Neurosci_240_349 |
| Author(s) : Li G , Klein J , Zimmermann M |
| Ref : Neuroscience , 240 :349 , 2013 |
| Abstract : Li_2013_Neurosci_240_349 |
| ESTHER : Li_2013_Neurosci_240_349 |
| PubMedSearch : Li_2013_Neurosci_240_349 |
| PubMedID: 23485809 |
| Title : Near-complete adaptation of the PRiMA knockout to the lack of central acetylcholinesterase - Farar_2012_J.Neurochem_122_1065 |
| Author(s) : Farar V , Mohr F , Legrand M , Lamotte d'Incamps B , Cendelin J , Leroy J , Abitbol M , Bernard V , Baud F , Fournet V , Houze P , Klein J , Plaud B , Tuma J , Zimmermann M , Ascher P , Hrabovska A , Myslivecek J , Krejci E |
| Ref : Journal of Neurochemistry , 122 :1065 , 2012 |
| Abstract : Farar_2012_J.Neurochem_122_1065 |
| ESTHER : Farar_2012_J.Neurochem_122_1065 |
| PubMedSearch : Farar_2012_J.Neurochem_122_1065 |
| PubMedID: 22747514 |
| Title : Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BCHE inhibition - Mohr_2012_Neuropharmacol_67C_37 |
| Author(s) : Mohr F , Zimmermann M , Klein J |
| Ref : Neuropharmacology , 67C :37 , 2012 |
| Abstract : Mohr_2012_Neuropharmacol_67C_37 |
| ESTHER : Mohr_2012_Neuropharmacol_67C_37 |
| PubMedSearch : Mohr_2012_Neuropharmacol_67C_37 |
| PubMedID: 23147415 |
| Title : Neurotransmitters and energy metabolites in amyloid-bearing APP(SWE)xPSEN1dE9 Mouse Brain - Hartmann_2010_J.Pharmacol.Exp.Ther_332_364 |
| Author(s) : Hartmann J , Kiewert C , Klein J |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 332 :364 , 2010 |
| Abstract : Hartmann_2010_J.Pharmacol.Exp.Ther_332_364 |
| ESTHER : Hartmann_2010_J.Pharmacol.Exp.Ther_332_364 |
| PubMedSearch : Hartmann_2010_J.Pharmacol.Exp.Ther_332_364 |
| PubMedID: 19846589 |
| Title : Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice - Naik_2009_J.Pharm.Pharm.Sci_12_79 |
| Author(s) : Naik RS , Hartmann J , Kiewert C , Duysen EG , Lockridge O , Klein J |
| Ref : J Pharm Pharm Sci , 12 :79 , 2009 |
| Abstract : Naik_2009_J.Pharm.Pharm.Sci_12_79 |
| ESTHER : Naik_2009_J.Pharm.Pharm.Sci_12_79 |
| PubMedSearch : Naik_2009_J.Pharm.Pharm.Sci_12_79 |
| PubMedID: 19470293 |
| Title : Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice - Hartmann_2008_Neurochem.Int_52_972 |
| Author(s) : Hartmann J , Kiewert C , Duysen EG , Lockridge O , Klein J |
| Ref : Neurochem Int , 52 :972 , 2008 |
| Abstract : Hartmann_2008_Neurochem.Int_52_972 |
| ESTHER : Hartmann_2008_Neurochem.Int_52_972 |
| PubMedSearch : Hartmann_2008_Neurochem.Int_52_972 |
| PubMedID: 18023504 |
| Title : Phenserine - Klein_2007_Expert.Opin.Investig.Drugs_16_1087 |
| Author(s) : Klein J |
| Ref : Expert Opin Investig Drugs , 16 :1087 , 2007 |
| Abstract : Klein_2007_Expert.Opin.Investig.Drugs_16_1087 |
| ESTHER : Klein_2007_Expert.Opin.Investig.Drugs_16_1087 |
| PubMedSearch : Klein_2007_Expert.Opin.Investig.Drugs_16_1087 |
| PubMedID: 17594192 |
| Title : Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity - Hartmann_2007_J.Neurochem_100_1421 |
| Author(s) : Hartmann J , Kiewert C , Duysen EG , Lockridge O , Greig NH , Klein J |
| Ref : Journal of Neurochemistry , 100 :1421 , 2007 |
| Abstract : Hartmann_2007_J.Neurochem_100_1421 |
| ESTHER : Hartmann_2007_J.Neurochem_100_1421 |
| PubMedSearch : Hartmann_2007_J.Neurochem_100_1421 |
| PubMedID: 17212694 |
| Title : Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes - Kralisch_2005_Mol.Cell.Endocrinol_240_43 |
| Author(s) : Kralisch S , Klein J , Lossner U , Bluher M , Paschke R , Stumvoll M , Fasshauer M |
| Ref : Mol Cell Endocrinol , 240 :43 , 2005 |
| Abstract : Kralisch_2005_Mol.Cell.Endocrinol_240_43 |
| ESTHER : Kralisch_2005_Mol.Cell.Endocrinol_240_43 |
| PubMedSearch : Kralisch_2005_Mol.Cell.Endocrinol_240_43 |
| PubMedID: 16009485 |
| Title : How is the brain protected against excess choline concentrations? - |
| Author(s) : Loffelholz K , Klein J |
| Ref : Cholinergic Mechanisms, CRC Press :395 , 2004 |
| PubMedID: |
| Title : Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients - Walter_2004_Neurobiol.Aging_25_1299 |
| Author(s) : Walter A , Korth U , Hilgert M , Hartmann J , Weichel O , Fassbender K , Schmitt A , Klein J |
| Ref : Neurobiology of Aging , 25 :1299 , 2004 |
| Abstract : Walter_2004_Neurobiol.Aging_25_1299 |
| ESTHER : Walter_2004_Neurobiol.Aging_25_1299 |
| PubMedSearch : Walter_2004_Neurobiol.Aging_25_1299 |
| PubMedID: 15465626 |
| Title : Conditions for a precursor control of acetylcholine release in mouse hippocampus. - |
| Author(s) : Klein J , Buchholzer ML , Kopf S , Loffelholz K |
| Ref : Cholinergic Mechanisms, CRC Press :399 , 2004 |
| PubMedID: |
| Title : Effects of septal grafts on acetylcholine release from rat hippocampus after 192 IgG-saporin lesion - Hilgert_2003_Neurochem.Res_28_467 |
| Author(s) : Hilgert M , Hartmann J , Loffelholz K , Jeltsch H , Cassel JC , Klein J |
| Ref : Neurochem Res , 28 :467 , 2003 |
| Abstract : Hilgert_2003_Neurochem.Res_28_467 |
| ESTHER : Hilgert_2003_Neurochem.Res_28_467 |
| PubMedSearch : Hilgert_2003_Neurochem.Res_28_467 |
| PubMedID: 12675132 |
| Title : A homeostatic mechanism counteracting K(+) -evoked choline release in adult brain - Klein_2002_J.Neurochem_80_843 |
| Author(s) : Klein J , Weichel O , Ruhr J , Dvorak C , Loffelholz K |
| Ref : Journal of Neurochemistry , 80 :843 , 2002 |
| Abstract : Klein_2002_J.Neurochem_80_843 |
| ESTHER : Klein_2002_J.Neurochem_80_843 |
| PubMedSearch : Klein_2002_J.Neurochem_80_843 |
| PubMedID: 11948248 |
| Title : Glucose plus choline improve passive avoidance behaviour and increase hippocampal acetylcholine release in mice - Kopf_2001_Neurosci_103_365 |
| Author(s) : Kopf SR , Buchholzer ML , Hilgert M , Loffelholz K , Klein J |
| Ref : Neuroscience , 103 :365 , 2001 |
| Abstract : Kopf_2001_Neurosci_103_365 |
| ESTHER : Kopf_2001_Neurosci_103_365 |
| PubMedSearch : Kopf_2001_Neurosci_103_365 |
| PubMedID: 11246151 |
| Title : Compensatory mechanisms enhance hippocampal acetylcholine release in transgenic mice expressing human acetylcholinesterase - Erb_2001_J.Neurochem_77_638 |
| Author(s) : Erb C , Troost J , Kopf S , Schmitt U , Loffelholz K , Soreq H , Klein J |
| Ref : Journal of Neurochemistry , 77 :638 , 2001 |
| Abstract : Erb_2001_J.Neurochem_77_638 |
| ESTHER : Erb_2001_J.Neurochem_77_638 |
| PubMedSearch : Erb_2001_J.Neurochem_77_638 |
| PubMedID: 11299326 |
| Title : KA-672 inhibits rat brain acetylcholinesterase in vitro but not in vivo - Hilgert_1999_Neurosci.Lett_263_193 |
| Author(s) : Hilgert M , Noldner M , Chatterjee SS , Klein J |
| Ref : Neuroscience Letters , 263 :193 , 1999 |
| Abstract : Hilgert_1999_Neurosci.Lett_263_193 |
| ESTHER : Hilgert_1999_Neurosci.Lett_263_193 |
| PubMedSearch : Hilgert_1999_Neurosci.Lett_263_193 |
| PubMedID: 10213168 |
| Title : Stimulatory and inhibitory effects of ethanol on hippocampal acetylcholine release - Henn_1998_Naunyn.Schmiedebergs.Arch.Pharmacol_357_640 |
| Author(s) : Henn C , Loffelholz K , Klein J |
| Ref : Naunyn Schmiedebergs Arch Pharmacol , 357 :640 , 1998 |
| Abstract : Henn_1998_Naunyn.Schmiedebergs.Arch.Pharmacol_357_640 |
| ESTHER : Henn_1998_Naunyn.Schmiedebergs.Arch.Pharmacol_357_640 |
| PubMedSearch : Henn_1998_Naunyn.Schmiedebergs.Arch.Pharmacol_357_640 |
| PubMedID: 9686940 |
| Title : Regulation of free choline in rat brain: dietary and pharmacological manipulations - Klein_1998_Neurochem.Int_32_479 |
| Author(s) : Klein J , Koppen A , Loffelholz K |
| Ref : Neurochem Int , 32 :479 , 1998 |
| Abstract : Klein_1998_Neurochem.Int_32_479 |
| ESTHER : Klein_1998_Neurochem.Int_32_479 |
| PubMedSearch : Klein_1998_Neurochem.Int_32_479 |
| PubMedID: 9676747 |
| Title : Elevated acetylcholine release in the hippocampus of transgenic mice expressing the human acetylcholinesterase - |
| Author(s) : Erb C , Klein J , Salmon A , Soreq H , Loffelholz K |
| Ref : Journal de Physiologie (Paris) , 92 :428 , 1998 |
| PubMedID: |
| Title : Stimulatory influence of ethanol on the septohippocampal cholinergic pathway. A role for GABA receptors? - |
| Author(s) : Henn C , Klein J , Loffelholz K |
| Ref : Journal de Physiologie (Paris) , 92 :439 , 1998 |
| PubMedID: |
| Title : Modulation of hippocampal acetylcholine release after fimbria-fornix lesions and septal transplantation in rats - Erb_1997_Neurosci.Lett_231_5 |
| Author(s) : Erb C , Klein J , Koppen A , Loffelholz K , Jeltsch H , Cassel JC |
| Ref : Neuroscience Letters , 231 :5 , 1997 |
| Abstract : Erb_1997_Neurosci.Lett_231_5 |
| ESTHER : Erb_1997_Neurosci.Lett_231_5 |
| PubMedSearch : Erb_1997_Neurosci.Lett_231_5 |
| PubMedID: 9280154 |
| Title : Phospholipid breakdown and choline release under hypoxic conditions: inhibition by bilobalide, a constituent of Ginkgo biloba - Klein_1997_Brain.Res_755_347 |
| Author(s) : Klein J , Chatterjee SS , Loffelholz K |
| Ref : Brain Research , 755 :347 , 1997 |
| Abstract : Klein_1997_Brain.Res_755_347 |
| ESTHER : Klein_1997_Brain.Res_755_347 |
| PubMedSearch : Klein_1997_Brain.Res_755_347 |
| PubMedID: 9175905 |
| Title : Acetylcholine release and choline availability in rat hippocampus: effects of exogenous choline and nicotinamide - Koppen_1997_J.Pharmacol.Exp.Ther_282_1139 |
| Author(s) : Koppen A , Klein J , Erb C , Loffelholz K |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 282 :1139 , 1997 |
| Abstract : Koppen_1997_J.Pharmacol.Exp.Ther_282_1139 |
| ESTHER : Koppen_1997_J.Pharmacol.Exp.Ther_282_1139 |
| PubMedSearch : Koppen_1997_J.Pharmacol.Exp.Ther_282_1139 |
| PubMedID: 9316819 |
| Title : Muscarinic activation of phosphatidylcholine hydrolysis - |
| Author(s) : Klein J , Lindmar R , Loffelholz K |
| Ref : Prog Brain Res , 109 :201 , 1996 |
| PubMedID: 9009708 |
| Title : Choline, a precursor of acetylcholine and phospholipids in the brain - |
| Author(s) : Loffelholz K , Klein J , Koppen A |
| Ref : Prog Brain Res , 98 :197 , 1993 |
| PubMedID: 8248509 |