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Title : Highly active enzymes by automated combinatorial backbone assembly and sequence design - Lapidoth_2018_Nat.Commun_9_2780 |
Author(s) : Lapidoth G , Khersonsky O , Lipsh R , Dym O , Albeck S , Rogotner S , Fleishman SJ |
Ref : Nat Commun , 9 :2780 , 2018 |
Abstract : Lapidoth_2018_Nat.Commun_9_2780 |
ESTHER : Lapidoth_2018_Nat.Commun_9_2780 |
PubMedSearch : Lapidoth_2018_Nat.Commun_9_2780 |
PubMedID: 30018322 |
Title : Directed evolution of serum paraoxonase PON3 by family shuffling and ancestor\/consensus mutagenesis, and its biochemical characterization - Khersonsky_2009_Biochemistry_48_6644 |
Author(s) : Khersonsky O , Rosenblat M , Toker L , Yacobson S , Hugenmatter A , Silman I , Sussman JL , Aviram M , Tawfik DS |
Ref : Biochemistry , 48 :6644 , 2009 |
Abstract : Khersonsky_2009_Biochemistry_48_6644 |
ESTHER : Khersonsky_2009_Biochemistry_48_6644 |
PubMedSearch : Khersonsky_2009_Biochemistry_48_6644 |
PubMedID: 19492856 |
Title : The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux - Rosenblat_2006_J.Biol.Chem_281_7657 |
Author(s) : Rosenblat M , Gaidukov L , Khersonsky O , Vaya J , Oren R , Tawfik DS , Aviram M |
Ref : Journal of Biological Chemistry , 281 :7657 , 2006 |
Abstract : Rosenblat_2006_J.Biol.Chem_281_7657 |
ESTHER : Rosenblat_2006_J.Biol.Chem_281_7657 |
PubMedSearch : Rosenblat_2006_J.Biol.Chem_281_7657 |
PubMedID: 16407304 |
Title : Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase - Amitai_2006_FEBS.J_273_1906 |
Author(s) : Amitai G , Gaidukov L , Adani R , Yishay S , Yacov G , Kushnir M , Teitlboim S , Lindenbaum M , Bel P , Khersonsky O , Tawfik DS , Meshulam H |
Ref : Febs J , 273 :1906 , 2006 |
Abstract : Amitai_2006_FEBS.J_273_1906 |
ESTHER : Amitai_2006_FEBS.J_273_1906 |
PubMedSearch : Amitai_2006_FEBS.J_273_1906 |
PubMedID: 16640555 |
Title : Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase - Khersonsky_2005_Biochemistry_44_6371 |
Author(s) : Khersonsky O , Tawfik DS |
Ref : Biochemistry , 44 :6371 , 2005 |
Abstract : Khersonsky_2005_Biochemistry_44_6371 |
ESTHER : Khersonsky_2005_Biochemistry_44_6371 |
PubMedSearch : Khersonsky_2005_Biochemistry_44_6371 |
PubMedID: 15835926 |
Title : The 'evolvability' of promiscuous protein functions - Aharoni_2005_Nat.Genet_37_73 |
Author(s) : Aharoni A , Gaidukov L , Khersonsky O , Mc QGS , Roodveldt C , Tawfik DS |
Ref : Nat Genet , 37 :73 , 2005 |
Abstract : Aharoni_2005_Nat.Genet_37_73 |
ESTHER : Aharoni_2005_Nat.Genet_37_73 |
PubMedSearch : Aharoni_2005_Nat.Genet_37_73 |
PubMedID: 15568024 |
Title : Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes - Harel_2004_Nat.Struct.Mol.Biol_11_412 |
Author(s) : Harel M , Aharoni A , Gaidukov L , Brumshtein B , Khersonsky O , Meged R , Dvir H , Ravelli RB , McCarthy A , Toker L , Silman I , Sussman JL , Tawfik DS |
Ref : Nat Struct Mol Biol , 11 :412 , 2004 |
Abstract : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
ESTHER : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
PubMedSearch : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
PubMedID: 15098021 |