Kemble G

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References (3)

Title : FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models - O'Farrell_2022_Sci.Rep_12_15661
Author(s) : O'Farrell M , Duke G , Crowley R , Buckley D , Martins EB , Bhattacharya D , Friedman SL , Kemble G
Ref : Sci Rep , 12 :15661 , 2022
Abstract : O'Farrell_2022_Sci.Rep_12_15661
ESTHER : O'Farrell_2022_Sci.Rep_12_15661
PubMedSearch : O'Farrell_2022_Sci.Rep_12_15661
PubMedID: 36123383

Title : FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression - Heuer_2017_EBioMedicine_16_51
Author(s) : Heuer TS , Ventura R , Mordec K , Lai J , Fridlib M , Buckley D , Kemble G
Ref : EBioMedicine , 16 :51 , 2017
Abstract : Heuer_2017_EBioMedicine_16_51
ESTHER : Heuer_2017_EBioMedicine_16_51
PubMedSearch : Heuer_2017_EBioMedicine_16_51
PubMedID: 28159572

Title : Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression - Ventura_2015_EBioMedicine_2_808
Author(s) : Ventura R , Mordec K , Waszczuk J , Wang Z , Lai J , Fridlib M , Buckley D , Kemble G , Heuer TS
Ref : EBioMedicine , 2 :808 , 2015
Abstract : Ventura_2015_EBioMedicine_2_808
ESTHER : Ventura_2015_EBioMedicine_2_808
PubMedSearch : Ventura_2015_EBioMedicine_2_808
PubMedID: 26425687