Full name : Jost Petr
First name : Petr
Mail : Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01,\; Biomedical Research Centre, University Hospital, Sokolska 581, 500 05, Hradec Kralove
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Country : Czech Republic
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| Title : Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity - Pulkrabkova_2023_Arch.Toxicol__ |
| Author(s) : Pulkrabkova L , Muckova L , Hrabinova M , Sorf A , Kobrlova T , Jost P , Bezdekova D , Korabecny J , Jun D , Soukup O |
| Ref : Archives of Toxicology , : , 2023 |
| Abstract : Pulkrabkova_2023_Arch.Toxicol__ |
| ESTHER : Pulkrabkova_2023_Arch.Toxicol__ |
| PubMedSearch : Pulkrabkova_2023_Arch.Toxicol__ |
| PubMedID: 37221426 |
| Title : Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness - Karasova_2020_Toxicol.Lett_320_64 |
| Author(s) : Karasova JZ , Hepnarova V , Andrys R , Lisa M , Jost P , Muckova L , Pejchal J , Herman D , Jun D , Kassa J , Kuca K |
| Ref : Toxicol Lett , 320 :64 , 2020 |
| Abstract : Karasova_2020_Toxicol.Lett_320_64 |
| ESTHER : Karasova_2020_Toxicol.Lett_320_64 |
| PubMedSearch : Karasova_2020_Toxicol.Lett_320_64 |
| PubMedID: 31794810 |
| Title : Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimes drugs dealing with cholinergic, amyloid and mitochondrial systems - Nepovimova_2020_Bioorg.Chem_107_104596 |
| Author(s) : Nepovimova E , Svobodova L , Dolezal R , Hepnarova V , Junova L , Jun D , Korabecny J , Kucera T , Gazova Z , Motykova K , Kubackova J , Bednarikova Z , Janockova J , Jesus C , Cortes L , Pina J , Rostohar D , Serpa C , Soukup O , Aitken L , Hughes RE , Musilek K , Muckova L , Jost P , Chvojkova M , Vales K , Valis M , Chrienova Z , Chalupova K , Kuca K |
| Ref : Bioorg Chem , 107 :104596 , 2020 |
| Abstract : Nepovimova_2020_Bioorg.Chem_107_104596 |
| ESTHER : Nepovimova_2020_Bioorg.Chem_107_104596 |
| PubMedSearch : Nepovimova_2020_Bioorg.Chem_107_104596 |
| PubMedID: 33421953 |
| Title : N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer's Disease Therapy - Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| Author(s) : Nepovimova E , Korabecny J , Hepnarova V , Jun D , Dolezal R , Muckova L , Jost P , Soukup O , Janockova J , Pham NL , Nguyen TD , Valis M , Kuca K |
| Ref : Curr Alzheimer Res , 16 :333 , 2019 |
| Abstract : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| ESTHER : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| PubMedSearch : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| PubMedID: 30873921 |
| Title : Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease - Chalupova_2019_Eur.J.Med.Chem_168_491 |
| Author(s) : Chalupova K , Korabecny J , Bartolini M , Monti B , Lamba D , Caliandro R , Pesaresi A , Brazzolotto X , Gastellier AJ , Nachon F , Pejchal J , Jarosova M , Hepnarova V , Jun D , Hrabinova M , Dolezal R , Karasova JZ , Mzik M , Kristofikova Z , Misik J , Muckova L , Jost P , Soukup O , Benkova M , Setnicka V , Habartova L , Chvojkova M , Kleteckova L , Vales K , Mezeiova E , Uliassi E , Valis M , Nepovimova E , Bolognesi ML , Kuca K |
| Ref : Eur Journal of Medicinal Chemistry , 168 :491 , 2019 |
| Abstract : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| ESTHER : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| PubMedSearch : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| PubMedID: 30851693 |
| Gene_locus related to this paper: torca-ACHE |
| Title : In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley? - Soukup_2018_Med.Chem_14_281 |
| Author(s) : Soukup O , Korabecny J , Malinak D , Nepovimova E , Pham NL , Musilek K , Hrabinova M , Hepnarova V , Dolezal R , Pavek P , Jost P , Kobrlova T , Jankockova J , Gorecki L , Psotka M , Nguyen TD , Box K , Outhwaite B , Ceckova M , Sorf A , Jun D , Kuca K |
| Ref : Med Chem , 14 :281 , 2018 |
| Abstract : Soukup_2018_Med.Chem_14_281 |
| ESTHER : Soukup_2018_Med.Chem_14_281 |
| PubMedSearch : Soukup_2018_Med.Chem_14_281 |
| PubMedID: 29332594 |
| Title : Cytotoxicity of acetylcholinesterase reactivators evaluated in vitro and its relation to their structure - Muckova_2018_Drug.Chem.Toxicol__1 |
| Author(s) : Muckova L , Pejchal J , Jost P , Vanova N , Herman D , Jun D |
| Ref : Drug & Chemical Toxicology , :1 , 2018 |
| Abstract : Muckova_2018_Drug.Chem.Toxicol__1 |
| ESTHER : Muckova_2018_Drug.Chem.Toxicol__1 |
| PubMedSearch : Muckova_2018_Drug.Chem.Toxicol__1 |
| PubMedID: 29421945 |
| Title : The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease - Hepnarova_2018_Eur.J.Med.Chem_150_292 |
| Author(s) : Hepnarova V , Korabecny J , Matouskova L , Jost P , Muckova L , Hrabinova M , Vykoukalova N , Kerhartova M , Kucera T , Dolezal R , Nepovimova E , Spilovska K , Mezeiova E , Pham NL , Jun D , Staud F , Kaping D , Kuca K , Soukup O |
| Ref : Eur Journal of Medicinal Chemistry , 150 :292 , 2018 |
| Abstract : Hepnarova_2018_Eur.J.Med.Chem_150_292 |
| ESTHER : Hepnarova_2018_Eur.J.Med.Chem_150_292 |
| PubMedSearch : Hepnarova_2018_Eur.J.Med.Chem_150_292 |
| PubMedID: 29533874 |
| Title : Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment - Gazova_2017_Biochim.Biophys.Acta.Mol.Basis.Dis_1863_607 |
| Author(s) : Gazova Z , Soukup O , Sepsova V , Siposova K , Drtinova L , Jost P , Spilovska K , Korabecny J , Nepovimova E , Fedunova D , Horak M , Kaniakova M , Wang ZJ , Hamouda AK , Kuca K |
| Ref : Biochimica & Biophysica Acta Mol Basis Dis , 1863 :607 , 2017 |
| Abstract : Gazova_2017_Biochim.Biophys.Acta.Mol.Basis.Dis_1863_607 |
| ESTHER : Gazova_2017_Biochim.Biophys.Acta.Mol.Basis.Dis_1863_607 |
| PubMedSearch : Gazova_2017_Biochim.Biophys.Acta.Mol.Basis.Dis_1863_607 |
| PubMedID: 27865910 |
| Title : Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation - Spilovska_2017_Molecules_22_ |
| Author(s) : Spilovska K , Korabecny J , Sepsova V , Jun D , Hrabinova M , Jost P , Muckova L , Soukup O , Janockova J , Kucera T , Dolezal R , Mezeiova E , Kaping D , Kuca K |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Spilovska_2017_Molecules_22_ |
| ESTHER : Spilovska_2017_Molecules_22_ |
| PubMedSearch : Spilovska_2017_Molecules_22_ |
| PubMedID: 28621747 |
| Title : Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy - Mezeiova_2017_Molecules_22_ |
| Author(s) : Mezeiova E , Korabecny J , Sepsova V , Hrabinova M , Jost P , Muckova L , Kucera T , Dolezal R , Misik J , Spilovska K , Pham NL , Pokrievkova L , Roh J , Jun D , Soukup O , Kaping D , Kuca K |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Mezeiova_2017_Molecules_22_ |
| ESTHER : Mezeiova_2017_Molecules_22_ |
| PubMedSearch : Mezeiova_2017_Molecules_22_ |
| PubMedID: 28788095 |
| Title : Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease - Benek_2016_ChemMedChem_11_1264 |
| Author(s) : Benek O , Soukup O , Pasdiorova M , Hroch L , Sepsova V , Jost P , Hrabinova M , Jun D , Kuca K , Zala D , Ramsay RR , Marco-Contelles J , Musilek K |
| Ref : ChemMedChem , 11 :1264 , 2016 |
| Abstract : Benek_2016_ChemMedChem_11_1264 |
| ESTHER : Benek_2016_ChemMedChem_11_1264 |
| PubMedSearch : Benek_2016_ChemMedChem_11_1264 |
| PubMedID: 26427608 |
| Title : A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication - Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| Author(s) : Nepovimova E , Korabecny J , Dolezal R , Nguyen TD , Jun D , Soukup O , Pasdiorova M , Jost P , Muckova L , Malinak D , Gorecki L , Musilek K , Kuca K |
| Ref : Toxicol Res (Camb) , 5 :1012 , 2016 |
| Abstract : Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| ESTHER : Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| PubMedSearch : Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| PubMedID: 30090408 |
| Title : Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity - Nepovimova_2015_J.Med.Chem_58_8985 |
| Author(s) : Nepovimova E , Korabecny J , Dolezal R , Babkova K , Ondrejicek A , Jun D , Sepsova V , Horova A , Hrabinova M , Soukup O , Bukum N , Jost P , Muckova L , Kassa J , Malinak D , Andrs M , Kuca K |
| Ref : Journal of Medicinal Chemistry , 58 :8985 , 2015 |
| Abstract : Nepovimova_2015_J.Med.Chem_58_8985 |
| ESTHER : Nepovimova_2015_J.Med.Chem_58_8985 |
| PubMedSearch : Nepovimova_2015_J.Med.Chem_58_8985 |
| PubMedID: 26503905 |
| Title : Cytotoxicity and genotoxicity evaluation of antidote oxime HI-6 tested on eight cell lines of human and rodent origin - Svobodova_2012_Gen.Physiol.Biophys_31_77 |
| Author(s) : Svobodova H , Jost P , Stetina R |
| Ref : Gen Physiol Biophys , 31 :77 , 2012 |
| Abstract : Svobodova_2012_Gen.Physiol.Biophys_31_77 |
| ESTHER : Svobodova_2012_Gen.Physiol.Biophys_31_77 |
| PubMedSearch : Svobodova_2012_Gen.Physiol.Biophys_31_77 |
| PubMedID: 22447833 |
| Title : Comparison of potential cytotoxicity and genotoxicity of selected antidotes against organophosphates inhibiting acetylcholinesterase - Svobodova_2011_Mil.Med.Sci.Lett_80_142 |
| Author(s) : Svobodova H , Jost P , Stetina R |
| Ref : Military Medical Science Letters , 80 :142 , 2011 |
| Abstract : Svobodova_2011_Mil.Med.Sci.Lett_80_142 |
| ESTHER : Svobodova_2011_Mil.Med.Sci.Lett_80_142 |
| PubMedSearch : Svobodova_2011_Mil.Med.Sci.Lett_80_142 |
| PubMedID: |
| Title : Photosuicide inactivation of acetylcholinesterase by nitrosamine derivatives - Eid_1981_Biochemistry_20_2251 |
| Author(s) : Eid P , Goeldner M , Hirth C , Jost P |
| Ref : Biochemistry , 20 :2251 , 1981 |
| Abstract : Eid_1981_Biochemistry_20_2251 |
| ESTHER : Eid_1981_Biochemistry_20_2251 |
| PubMedSearch : Eid_1981_Biochemistry_20_2251 |
| PubMedID: 7236595 |