Full name : Janockova Jana
First name : Jana
Mail : Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove
Zip Code :
City :
Country : Czech Republic
Email :
Phone :
Fax :
Website :
Directory :
| Title : Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities - Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| Author(s) : Chrienova Z , Nepovimova E , Andrys R , Dolezal R , Janockova J , Muckova L , Fabova L , Soukup O , Oleksak P , Valis M , Korabecny J , Marco-Contelles J , Kuca K |
| Ref : J Enzyme Inhib Med Chem , 37 :2605 , 2022 |
| Abstract : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| ESTHER : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| PubMedSearch : Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 |
| PubMedID: 36131624 |
| Title : (+\/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease - Ismaili_2021_ACS.Chem.Neurosci__ |
| Author(s) : Ismaili L , Monnin J , Etievant A , Arribas RL , Viejo L , Refouvelet B , Soukup O , Janockova J , Hepnarova V , Korabecny J , Kucera T , Jun D , Andrys R , Musilek K , Baguet A , Garcia-Frutos EM , De Simone A , Andrisano V , Bartolini M , de los Rios C , Marco-Contelles J , Haffen E |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : Ismaili_2021_ACS.Chem.Neurosci__ |
| ESTHER : Ismaili_2021_ACS.Chem.Neurosci__ |
| PubMedSearch : Ismaili_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33797877 |
| Title : Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease - Hamulakova_2021_Future.Med.Chem__ |
| Author(s) : Hamulakova S , Kudlickova Z , Janovec L , Mezencev R , Deckner ZJ , Chernoff YO , Janockova J , Ihnatova V , Bzonek P , Novakova N , Hepnarova V , Hrabinova M , Jun D , Korabecny J , Soukup O , Kuca K |
| Ref : Future Med Chem , : , 2021 |
| Abstract : Hamulakova_2021_Future.Med.Chem__ |
| ESTHER : Hamulakova_2021_Future.Med.Chem__ |
| PubMedSearch : Hamulakova_2021_Future.Med.Chem__ |
| PubMedID: 33829876 |
| Title : Huprine Y - tryptophan heterodimers with potential implication to Alzheimer's disease treatment - Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| Author(s) : Mezeiova E , Hrabinova M , Hepnarova V , Jun D , Janockova J , Muckova L , Prchal L , Kristofikova Z , Kucera T , Gorecki L , Chalupova K , Kunes J , Hroudova J , Soukup O , Korabecny J |
| Ref : Bioorganic & Medicinal Chemistry Lett , :128100 , 2021 |
| Abstract : Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| ESTHER : Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| PubMedSearch : Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| PubMedID: 33984470 |
| Title : Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells - Hudacova_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Hudacova M , Hamuakova S , Konkoova E , Jendzelovsky R , Vargova J , Sevc J , Fedorocko P , Soukup O , Janockova J , Ihnatova V , Kucera T , Bzonek P , Novakova N , Jun D , Junova L , Korabecny J , Kuca K , Kozurkova M |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : Hudacova_2021_Int.J.Mol.Sci_22_ |
| ESTHER : Hudacova_2021_Int.J.Mol.Sci_22_ |
| PubMedSearch : Hudacova_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33917200 |
| Title : Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease - Gorecki_2021_ACS.Chem.Neurosci__ |
| Author(s) : Gorecki L , Uliassi E , Bartolini M , Janockova J , Hrabinova M , Hepnarova V , Prchal L , Muckova L , Pejchal J , Karasova JZ , Mezeiova E , Benkova M , Kobrlova T , Soukup O , Petralla S , Monti B , Korabecny J , Bolognesi ML |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : Gorecki_2021_ACS.Chem.Neurosci__ |
| ESTHER : Gorecki_2021_ACS.Chem.Neurosci__ |
| PubMedSearch : Gorecki_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33852284 |
| Title : Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile - Sobolova_2020_Eur.J.Med.Chem_203_112593 |
| Author(s) : Sobolova K , Hrabinova M , Hepnarova V , Kucera T , Kobrlova T , Benkova M , Janockova J , Dolezal R , Prchal L , Benek O , Mezeiova E , Jun D , Soukup O , Korabecny J |
| Ref : Eur Journal of Medicinal Chemistry , 203 :112593 , 2020 |
| Abstract : Sobolova_2020_Eur.J.Med.Chem_203_112593 |
| ESTHER : Sobolova_2020_Eur.J.Med.Chem_203_112593 |
| PubMedSearch : Sobolova_2020_Eur.J.Med.Chem_203_112593 |
| PubMedID: 32688201 |
| Title : From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia - Mezeiova_2020_Bioorg.Chem_103_104179 |
| Author(s) : Mezeiova E , Janockova J , Konecny J , Kobrlova T , Benkova M , Dolezal R , Prchal L , Karasova-Zdarova J , Soukup O , Korabecny J |
| Ref : Bioorg Chem , 103 :104179 , 2020 |
| Abstract : Mezeiova_2020_Bioorg.Chem_103_104179 |
| ESTHER : Mezeiova_2020_Bioorg.Chem_103_104179 |
| PubMedSearch : Mezeiova_2020_Bioorg.Chem_103_104179 |
| PubMedID: 32891860 |
| Title : Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimes drugs dealing with cholinergic, amyloid and mitochondrial systems - Nepovimova_2020_Bioorg.Chem_107_104596 |
| Author(s) : Nepovimova E , Svobodova L , Dolezal R , Hepnarova V , Junova L , Jun D , Korabecny J , Kucera T , Gazova Z , Motykova K , Kubackova J , Bednarikova Z , Janockova J , Jesus C , Cortes L , Pina J , Rostohar D , Serpa C , Soukup O , Aitken L , Hughes RE , Musilek K , Muckova L , Jost P , Chvojkova M , Vales K , Valis M , Chrienova Z , Chalupova K , Kuca K |
| Ref : Bioorg Chem , 107 :104596 , 2020 |
| Abstract : Nepovimova_2020_Bioorg.Chem_107_104596 |
| ESTHER : Nepovimova_2020_Bioorg.Chem_107_104596 |
| PubMedSearch : Nepovimova_2020_Bioorg.Chem_107_104596 |
| PubMedID: 33421953 |
| Title : Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase - AlFadly_2019_Eur.J.Med.Chem_167_161 |
| Author(s) : AlFadly ED , Elzahhar PA , Tramarin A , Elkazaz S , Shaltout H , Abu-Serie MM , Janockova J , Soukup O , Ghareeb DA , El-Yazbi AF , Rafeh RW , Bakkar NZ , Kobeissy F , Iriepa I , Moraleda I , Saudi MNS , Bartolini M , Belal ASF |
| Ref : Eur Journal of Medicinal Chemistry , 167 :161 , 2019 |
| Abstract : AlFadly_2019_Eur.J.Med.Chem_167_161 |
| ESTHER : AlFadly_2019_Eur.J.Med.Chem_167_161 |
| PubMedSearch : AlFadly_2019_Eur.J.Med.Chem_167_161 |
| PubMedID: 30771604 |
| Title : N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer's Disease Therapy - Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| Author(s) : Nepovimova E , Korabecny J , Hepnarova V , Jun D , Dolezal R , Muckova L , Jost P , Soukup O , Janockova J , Pham NL , Nguyen TD , Valis M , Kuca K |
| Ref : Curr Alzheimer Res , 16 :333 , 2019 |
| Abstract : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| ESTHER : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| PubMedSearch : Nepovimova_2019_Curr.Alzheimer.Res_16_333 |
| PubMedID: 30873921 |
| Title : Orexin supplementation in narcolepsy treatment: A review - Nepovimova_2019_Med.Res.Rev_39_961 |
| Author(s) : Nepovimova E , Janockova J , Misik J , Kubik S , Stuchlik A , Vales K , Korabecny J , Mezeiova E , Dolezal R , Soukup O , Kobrlova T , Pham NL , Nguyen TD , Konecny J , Kuca K |
| Ref : Med Res Rev , 39 :961 , 2019 |
| Abstract : Nepovimova_2019_Med.Res.Rev_39_961 |
| ESTHER : Nepovimova_2019_Med.Res.Rev_39_961 |
| PubMedSearch : Nepovimova_2019_Med.Res.Rev_39_961 |
| PubMedID: 30426515 |
| Title : In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers - Janockova_2019_J.Enzyme.Inhib.Med.Chem_34_877 |
| Author(s) : Janockova J , Korabecny J , Plsikova J , Babkova K , Konkolova E , Kucerova D , Vargova J , Koval J , Jendzelovsky R , Fedorocko P , Kasparkova J , Brabec V , Rosocha J , Soukup O , Hamulakova S , Kuca K , Kozurkova M |
| Ref : J Enzyme Inhib Med Chem , 34 :877 , 2019 |
| Abstract : Janockova_2019_J.Enzyme.Inhib.Med.Chem_34_877 |
| ESTHER : Janockova_2019_J.Enzyme.Inhib.Med.Chem_34_877 |
| PubMedSearch : Janockova_2019_J.Enzyme.Inhib.Med.Chem_34_877 |
| PubMedID: 30938202 |
| Title : Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives - Jonczyk_2019_Bioorg.Chem_90_103084 |
| Author(s) : Jonczyk J , Lodarski K , Staszewski M , Godyn J , Zareba P , Soukup O , Janockova J , Korabecny J , Salat K , Malikowska-Racia N , Hebda M , Szalaj N , Filipek B , Walczynski K , Malawska B , Bajda M |
| Ref : Bioorg Chem , 90 :103084 , 2019 |
| Abstract : Jonczyk_2019_Bioorg.Chem_90_103084 |
| ESTHER : Jonczyk_2019_Bioorg.Chem_90_103084 |
| PubMedSearch : Jonczyk_2019_Bioorg.Chem_90_103084 |
| PubMedID: 31271942 |
| Title : Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy - Dgachi_2019_J.Enzyme.Inhib.Med.Chem_34_163 |
| Author(s) : Dgachi Y , Martin H , Malek R , Jun D , Janockova J , Sepsova V , Soukup O , Iriepa I , Moraleda I , Maalej E , Carreiras MC , Refouvelet B , Chabchoub F , Marco-Contelles J , Ismaili L |
| Ref : J Enzyme Inhib Med Chem , 34 :163 , 2019 |
| Abstract : Dgachi_2019_J.Enzyme.Inhib.Med.Chem_34_163 |
| ESTHER : Dgachi_2019_J.Enzyme.Inhib.Med.Chem_34_163 |
| PubMedSearch : Dgachi_2019_J.Enzyme.Inhib.Med.Chem_34_163 |
| PubMedID: 30482062 |
| Title : Profiling donepezil template into multipotent hybrids with antioxidant properties - Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| Author(s) : Mezeiova E , Spilovska K , Nepovimova E , Gorecki L , Soukup O , Dolezal R , Malinak D , Janockova J , Jun D , Kuca K , Korabecny J |
| Ref : J Enzyme Inhib Med Chem , 33 :583 , 2018 |
| Abstract : Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| ESTHER : Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| PubMedSearch : Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| PubMedID: 29529892 |
| Title : Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier - Hamulakova_2018_Curr.Alzheimer.Res_15_1096 |
| Author(s) : Hamulakova S , Janovec L , Soukup O , Jun D , Janockova J , Hrabinova M , Sepsova V , Kuca K |
| Ref : Curr Alzheimer Res , 15 :1096 , 2018 |
| Abstract : Hamulakova_2018_Curr.Alzheimer.Res_15_1096 |
| ESTHER : Hamulakova_2018_Curr.Alzheimer.Res_15_1096 |
| PubMedSearch : Hamulakova_2018_Curr.Alzheimer.Res_15_1096 |
| PubMedID: 29992880 |
| Title : Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods - Janockova_2018_Molecules_23_ |
| Author(s) : Janockova J , Dolezal R , Nepovimova E , Kobrlova T , Benkova M , Kuca K , Konecny J , Mezeiova E , Melikova M , Hepnarova V , Ring A , Soukup O , Korabecny J |
| Ref : Molecules , 23 : , 2018 |
| Abstract : Janockova_2018_Molecules_23_ |
| ESTHER : Janockova_2018_Molecules_23_ |
| PubMedSearch : Janockova_2018_Molecules_23_ |
| PubMedID: 30423961 |
| Title : Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation - Spilovska_2017_Molecules_22_ |
| Author(s) : Spilovska K , Korabecny J , Sepsova V , Jun D , Hrabinova M , Jost P , Muckova L , Soukup O , Janockova J , Kucera T , Dolezal R , Mezeiova E , Kaping D , Kuca K |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Spilovska_2017_Molecules_22_ |
| ESTHER : Spilovska_2017_Molecules_22_ |
| PubMedSearch : Spilovska_2017_Molecules_22_ |
| PubMedID: 28621747 |
| Title : Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases - Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| Author(s) : Bautista-Aguilera OM , Hagenow S , Palomino-Antolin A , Farre-Alins V , Ismaili L , Joffrin PL , Jimeno ML , Soukup O , Janockova J , Kalinowsky L , Proschak E , Iriepa I , Moraleda I , Schwed JS , Romero Martinez A , Lopez-Munoz F , Chioua M , Egea J , Ramsay RR , Marco-Contelles J , Stark H |
| Ref : Angew Chem Int Ed Engl , 56 :12765 , 2017 |
| Abstract : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| ESTHER : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| PubMedSearch : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| PubMedID: 28861918 |
| Title : Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity - Janockova_2016_Mol.Biosyst_12_2910 |
| Author(s) : Janockova J , Zilecka E , Kasparkova J , Brabec V , Soukup O , Kuca K , Kozurkova M |
| Ref : Mol Biosyst , 12 :2910 , 2016 |
| Abstract : Janockova_2016_Mol.Biosyst_12_2910 |
| ESTHER : Janockova_2016_Mol.Biosyst_12_2910 |
| PubMedSearch : Janockova_2016_Mol.Biosyst_12_2910 |
| PubMedID: 27412811 |
| Title : Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation - Panek_2016_Eur.J.Med.Chem_125_676 |
| Author(s) : Panek D , Wieckowska A , Wichur T , Bajda M , Godyn J , Jonczyk J , Mika K , Janockova J , Soukup O , Knez D , Korabecny J , Gobec S , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 125 :676 , 2016 |
| Abstract : Panek_2016_Eur.J.Med.Chem_125_676 |
| ESTHER : Panek_2016_Eur.J.Med.Chem_125_676 |
| PubMedSearch : Panek_2016_Eur.J.Med.Chem_125_676 |
| PubMedID: 27721153 |
| Title : Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy - Dgachi_2016_Eur.J.Med.Chem_126_576 |
| Author(s) : Dgachi Y , Sokolov O , Luzet V , Godyn J , Panek D , Bonet A , Martin H , Iriepa I , Moraleda I , Garcia-Iriepa C , Janockova J , Richert L , Soukup O , Malawska B , Chabchoub F , Marco-Contelles J , Ismaili L |
| Ref : Eur Journal of Medicinal Chemistry , 126 :576 , 2016 |
| Abstract : Dgachi_2016_Eur.J.Med.Chem_126_576 |
| ESTHER : Dgachi_2016_Eur.J.Med.Chem_126_576 |
| PubMedSearch : Dgachi_2016_Eur.J.Med.Chem_126_576 |
| PubMedID: 27918993 |
| Title : The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators - Benchekroun_2016_J.Med.Chem_59_9967 |
| Author(s) : Benchekroun M , Romero A , Egea J , Leon R , Michalska P , Buendia I , Jimeno ML , Jun D , Janockova J , Sepsova V , Soukup O , Bautista-Aguilera OM , Refouvelet B , Ouari O , Marco-Contelles J , Ismaili L |
| Ref : Journal of Medicinal Chemistry , 59 :9967 , 2016 |
| Abstract : Benchekroun_2016_J.Med.Chem_59_9967 |
| ESTHER : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedSearch : Benchekroun_2016_J.Med.Chem_59_9967 |
| PubMedID: 27736061 |
| Title : Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease - Dgachi_2016_Molecules_21_ |
| Author(s) : Dgachi Y , Bautista-Aguilera OM , Benchekroun M , Martin H , Bonet A , Knez D , Godyn J , Malawska B , Gobec S , Chioua M , Janockova J , Soukup O , Chabchoub F , Marco-Contelles J , Ismaili L |
| Ref : Molecules , 21 : , 2016 |
| Abstract : Dgachi_2016_Molecules_21_ |
| ESTHER : Dgachi_2016_Molecules_21_ |
| PubMedSearch : Dgachi_2016_Molecules_21_ |
| PubMedID: 27187348 |
| Title : Novel cholinesterase modulators and their ability to interact with DNA - Janockova_2013_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_115C_364 |
| Author(s) : Janockova J , Gulasova Z , Musilek K , Kuca K , Kozurkova M |
| Ref : Spectrochim Acta A Mol Biomol Spectrosc , 115C :364 , 2013 |
| Abstract : Janockova_2013_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_115C_364 |
| ESTHER : Janockova_2013_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_115C_364 |
| PubMedSearch : Janockova_2013_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_115C_364 |
| PubMedID: 23851179 |
| Title : Interaction of cholinesterase modulators with DNA and their cytotoxic activity - Janockova_2013_Int.J.Biol.Macromol_64C_53 |
| Author(s) : Janockova J , Gulasova Z , Plsikova J , Musilek K , Kuca K , Mikes J , Culka L , Fedorocko P , Kozurkova M |
| Ref : Int J Biol Macromol , 64C :53 , 2013 |
| Abstract : Janockova_2013_Int.J.Biol.Macromol_64C_53 |
| ESTHER : Janockova_2013_Int.J.Biol.Macromol_64C_53 |
| PubMedSearch : Janockova_2013_Int.J.Biol.Macromol_64C_53 |
| PubMedID: 24296409 |