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| Title : Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy - Panigrahy_2024_bioRxiv__ |
| Author(s) : Panigrahy D , Kelly A , Wang W , Yang J , Hwang SH , Gillespie M , Howard I , Bueno-Beti C , Asimaki A , Penna V , Lavine K , Edin M , Zeldin D , Hammock B , Saffitz J |
| Ref : Biorxiv , : , 2024 |
| Abstract : Panigrahy_2024_bioRxiv__ |
| ESTHER : Panigrahy_2024_bioRxiv__ |
| PubMedSearch : Panigrahy_2024_bioRxiv__ |
| PubMedID: 38463975 |
| Title : Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase - Kelly_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2314085121 |
| Author(s) : Kelly AG , Wang W , Rothenberger E , Yang J , Gilligan MM , Kipper FC , Attaya A , Gartung A , Hwang SH , Gillespie MJ , Bayer RL , Quinlivan KM , Torres KL , Huang S , Mitsiades N , Yang H , Hammock BD , Panigrahy D |
| Ref : Proc Natl Acad Sci U S A , 121 :e2314085121 , 2024 |
| Abstract : Kelly_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2314085121 |
| ESTHER : Kelly_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2314085121 |
| PubMedSearch : Kelly_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2314085121 |
| PubMedID: 38330013 |
| Title : Inhibition of Soluble Epoxide Hydrolase Reduces Paraquat Neurotoxicity in Rodents - Atone_2023_Environ.Toxicol.Pharmacol__104070 |
| Author(s) : Atone J , Wagner K , Koike S , Yang J , Hwang SH , Hammock BD |
| Ref : Environ Toxicol Pharmacol , :104070 , 2023 |
| Abstract : Atone_2023_Environ.Toxicol.Pharmacol__104070 |
| ESTHER : Atone_2023_Environ.Toxicol.Pharmacol__104070 |
| PubMedSearch : Atone_2023_Environ.Toxicol.Pharmacol__104070 |
| PubMedID: 36682504 |
| Title : Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice - Kulkarni_2023_Biochem.Biophys.Res.Commun_667_64 |
| Author(s) : Kulkarni R , Mehta R , Goswami SK , Hammock BD , Morisseau C , Hwang SH , Mallappa O , Azeemuddin MM , Rafiq M , S NM |
| Ref : Biochemical & Biophysical Research Communications , 667 :64 , 2023 |
| Abstract : Kulkarni_2023_Biochem.Biophys.Res.Commun_667_64 |
| ESTHER : Kulkarni_2023_Biochem.Biophys.Res.Commun_667_64 |
| PubMedSearch : Kulkarni_2023_Biochem.Biophys.Res.Commun_667_64 |
| PubMedID: 37209564 |
| Title : Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA - Yang_2023_J.Pharm.Anal_13_1013 |
| Author(s) : Yang H , Qi M , He Q , Hwang SH , Yang J , McCoy M , Morisseau C , Zhao S , Hammock BD |
| Ref : J Pharm Anal , 13 :1013 , 2023 |
| Abstract : Yang_2023_J.Pharm.Anal_13_1013 |
| ESTHER : Yang_2023_J.Pharm.Anal_13_1013 |
| PubMedSearch : Yang_2023_J.Pharm.Anal_13_1013 |
| PubMedID: 37842656 |
| Title : Aflatoxin B(1) Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity - Wang_2023_Int.J.Mol.Sci_24_9938 |
| Author(s) : Wang W , Wang Y , Wagner KM , Lee RD , Hwang SH , Morisseau C , Wulff H , Hammock BD |
| Ref : Int J Mol Sci , 24 :9938 , 2023 |
| Abstract : Wang_2023_Int.J.Mol.Sci_24_9938 |
| ESTHER : Wang_2023_Int.J.Mol.Sci_24_9938 |
| PubMedSearch : Wang_2023_Int.J.Mol.Sci_24_9938 |
| PubMedID: 37373086 |
| Title : Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble epoxide hydrolase in mice - Pan_2023_Front.Physiol_14_1185744 |
| Author(s) : Pan S , Karey E , Nieves-Cintron M , Chen YJ , Hwang SH , Hammock BD , Pinkerton KE , Chen CY |
| Ref : Front Physiol , 14 :1185744 , 2023 |
| Abstract : Pan_2023_Front.Physiol_14_1185744 |
| ESTHER : Pan_2023_Front.Physiol_14_1185744 |
| PubMedSearch : Pan_2023_Front.Physiol_14_1185744 |
| PubMedID: 37362438 |
| Title : Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis - Kim_2023_bioRxiv__ |
| Author(s) : Kim D , Horimatsu T , Ogbi M , Goo B , Shi H , Veerapaneni P , Chouhaita R , Moses M , Prasad R , Benson TW , Harb R , Aboud G , Seller H , Haigh S , Fulton DJ , Csanyi G , Huo Y , Long X , Coffey P , Lee R , Guha A , Zeldin D , Hwang SH , Hammock BD , Weintraub NL , Kim HW |
| Ref : Biorxiv , : , 2023 |
| Abstract : Kim_2023_bioRxiv__ |
| ESTHER : Kim_2023_bioRxiv__ |
| PubMedSearch : Kim_2023_bioRxiv__ |
| PubMedID: 37503031 |
| Title : Aflatoxin B(1) exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner - Wang_2022_Ecotoxicol.Environ.Saf_249_114417 |
| Author(s) : Wang W , Wang Y , Yang J , Wagner KM , Hwang SH , Cheng J , Singh N , Edwards P , Morisseau C , Zhang G , Panigrahy D , Hammock BD |
| Ref : Ecotoxicology & Environmental Safety , 249 :114417 , 2022 |
| Abstract : Wang_2022_Ecotoxicol.Environ.Saf_249_114417 |
| ESTHER : Wang_2022_Ecotoxicol.Environ.Saf_249_114417 |
| PubMedSearch : Wang_2022_Ecotoxicol.Environ.Saf_249_114417 |
| PubMedID: 36525946 |
| Title : Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products - Sun_2021_J.Med.Chem_64_184 |
| Author(s) : Sun CP , Zhang XY , Morisseau C , Hwang SH , Zhang ZJ , Hammock BD , Ma XC |
| Ref : Journal of Medicinal Chemistry , 64 :184 , 2021 |
| Abstract : Sun_2021_J.Med.Chem_64_184 |
| ESTHER : Sun_2021_J.Med.Chem_64_184 |
| PubMedSearch : Sun_2021_J.Med.Chem_64_184 |
| PubMedID: 33369424 |
| Title : Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative - Hammock_2021_J.Med.Chem__ |
| Author(s) : Hammock BD , McReynolds CB , Wagner K , Buckpitt A , Cortes-Puch I , Croston G , Lee KSS , Yang J , Schmidt WK , Hwang SH |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Hammock_2021_J.Med.Chem__ |
| ESTHER : Hammock_2021_J.Med.Chem__ |
| PubMedSearch : Hammock_2021_J.Med.Chem__ |
| PubMedID: 33550801 |
| Title : Dual sEH\/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity - Jankiewicz_2021_Front.Pharmacol_12_744776 |
| Author(s) : Jankiewicz WK , Barnett SD , Stavniichuk A , Hwang SH , Hammock BD , Belayet JB , Khan AH , Imig JD |
| Ref : Front Pharmacol , 12 :744776 , 2021 |
| Abstract : Jankiewicz_2021_Front.Pharmacol_12_744776 |
| ESTHER : Jankiewicz_2021_Front.Pharmacol_12_744776 |
| PubMedSearch : Jankiewicz_2021_Front.Pharmacol_12_744776 |
| PubMedID: 34955823 |
| Title : Multitarget molecule,PTUPB, to treat diabetic nephropathy in rats - Hye_2021_Br.J.Pharmacol_178_4468 |
| Author(s) : Hye Khan MA , Hwang SH , Barnett SD , Stavniichuk A , Jankiewicz WK , Hammock BD , Imig JD |
| Ref : British Journal of Pharmacology , 178 :4468 , 2021 |
| Abstract : Hye_2021_Br.J.Pharmacol_178_4468 |
| ESTHER : Hye_2021_Br.J.Pharmacol_178_4468 |
| PubMedSearch : Hye_2021_Br.J.Pharmacol_178_4468 |
| PubMedID: 34255857 |
| Title : COX-2\/sEH Dual Inhibitor PTUPB Alleviates CCl (4) -Induced Liver Fibrosis and Portal Hypertension - Zhao_2021_Front.Med.(Lausanne)_8_761517 |
| Author(s) : Zhao Z , Zhang C , Lin J , Zheng L , Li H , Qi X , Huo H , Lou X , Hammock BD , Hwang SH , Bao Y , Luo M |
| Ref : Front Med (Lausanne) , 8 :761517 , 2021 |
| Abstract : Zhao_2021_Front.Med.(Lausanne)_8_761517 |
| ESTHER : Zhao_2021_Front.Med.(Lausanne)_8_761517 |
| PubMedSearch : Zhao_2021_Front.Med.(Lausanne)_8_761517 |
| PubMedID: 35004731 |
| Title : Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development - McReynolds_2021_Molecules_26_ |
| Author(s) : McReynolds CB , Yang J , Guedes A , Morisseau C , Garcia R , Knych H , Tearney C , Hamamoto B , Hwang SH , Wagner K , Hammock BD |
| Ref : Molecules , 26 : , 2021 |
| Abstract : McReynolds_2021_Molecules_26_ |
| ESTHER : McReynolds_2021_Molecules_26_ |
| PubMedSearch : McReynolds_2021_Molecules_26_ |
| PubMedID: 34443621 |
| Title : Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain - Lee_2020_Bioorg.Med.Chem_28_115735 |
| Author(s) : Lee KSS , Ng JC , Yang J , Hwang SH , Morisseau C , Wagner K , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry , 28 :115735 , 2020 |
| Abstract : Lee_2020_Bioorg.Med.Chem_28_115735 |
| ESTHER : Lee_2020_Bioorg.Med.Chem_28_115735 |
| PubMedSearch : Lee_2020_Bioorg.Med.Chem_28_115735 |
| PubMedID: 33007552 |
| Title : Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase - Pu_2020_Proc.Natl.Acad.Sci.U.S.A__ |
| Author(s) : Pu Y , Yang J , Chang L , Qu Y , Wang S , Zhang K , Xiong Z , Zhang J , Tan Y , Wang X , Fujita Y , Ishima T , Wan D , Hwang SH , Hammock BD , Hashimoto K |
| Ref : Proc Natl Acad Sci U S A , : , 2020 |
| Abstract : Pu_2020_Proc.Natl.Acad.Sci.U.S.A__ |
| ESTHER : Pu_2020_Proc.Natl.Acad.Sci.U.S.A__ |
| PubMedSearch : Pu_2020_Proc.Natl.Acad.Sci.U.S.A__ |
| PubMedID: 32398374 |
| Title : PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice - Sun_2020_Biochem.Biophys.Res.Commun__ |
| Author(s) : Sun CC , Zhang CY , Duan JX , Guan XX , Yang HH , Jiang HL , Hammock BD , Hwang SH , Zhou Y , Guan CX , Liu SK , Zhang J |
| Ref : Biochemical & Biophysical Research Communications , : , 2020 |
| Abstract : Sun_2020_Biochem.Biophys.Res.Commun__ |
| ESTHER : Sun_2020_Biochem.Biophys.Res.Commun__ |
| PubMedSearch : Sun_2020_Biochem.Biophys.Res.Commun__ |
| PubMedID: 31973813 |
| Title : Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation - Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| Author(s) : Wang Y , Yang J , Wang W , Sanidad KZ , Cinelli MA , Wan D , Hwang SH , Kim D , Lee KSS , Xiao H , Hammock BD , Zhang G |
| Ref : Proc Natl Acad Sci U S A , 117 :8431 , 2020 |
| Abstract : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| ESTHER : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| PubMedSearch : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| PubMedID: 32220957 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : A COX-2\/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation - Yang_2020_Theranostics_10_4749 |
| Author(s) : Yang HH , Duan JX , Liu SK , Xiong JB , Guan XX , Zhong WJ , Sun CC , Zhang CY , Luo XQ , Zhang YF , Chen P , Hammock BD , Hwang SH , Jiang JX , Zhou Y , Guan CX |
| Ref : Theranostics , 10 :4749 , 2020 |
| Abstract : Yang_2020_Theranostics_10_4749 |
| ESTHER : Yang_2020_Theranostics_10_4749 |
| PubMedSearch : Yang_2020_Theranostics_10_4749 |
| PubMedID: 32308747 |
| Title : A COX-2\/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress - Zhang_2020_Biomed.Pharmacother_126_109907 |
| Author(s) : Zhang YF , Sun CC , Duan JX , Yang HH , Zhang CY , Xiong JB , Zhong WJ , Zu C , Guan XX , Jiang HL , Hammock BD , Hwang SH , Zhou Y , Guan CX |
| Ref : Biomed Pharmacother , 126 :109907 , 2020 |
| Abstract : Zhang_2020_Biomed.Pharmacother_126_109907 |
| ESTHER : Zhang_2020_Biomed.Pharmacother_126_109907 |
| PubMedSearch : Zhang_2020_Biomed.Pharmacother_126_109907 |
| PubMedID: 32114358 |
| Title : COX-2\/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence - Zhang_2020_FEBS.J_287_1666 |
| Author(s) : Zhang CY , Duan JX , Yang HH , Sun CC , Zhong WJ , Tao JH , Guan XX , Jiang HL , Hammock BD , Hwang SH , Zhou Y , Guan CX |
| Ref : Febs J , 287 :1666 , 2020 |
| Abstract : Zhang_2020_FEBS.J_287_1666 |
| ESTHER : Zhang_2020_FEBS.J_287_1666 |
| PubMedSearch : Zhang_2020_FEBS.J_287_1666 |
| PubMedID: 31646730 |
| Title : Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine - Shihadih_2020_Front.Vet.Sci_7_580 |
| Author(s) : Shihadih DS , Harris TR , Kodani SD , Hwang SH , Lee KSS , Mavangira V , Hamamoto B , Guedes A , Hammock BD , Morisseau C |
| Ref : Front Vet Sci , 7 :580 , 2020 |
| Abstract : Shihadih_2020_Front.Vet.Sci_7_580 |
| ESTHER : Shihadih_2020_Front.Vet.Sci_7_580 |
| PubMedSearch : Shihadih_2020_Front.Vet.Sci_7_580 |
| PubMedID: 33005645 |
| Title : An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease - Ghosh_2020_Sci.Transl.Med_12_ |
| Author(s) : Ghosh A , Comerota MM , Wan D , Chen F , Propson NE , Hwang SH , Hammock BD , Zheng H |
| Ref : Sci Transl Med , 12 : , 2020 |
| Abstract : Ghosh_2020_Sci.Transl.Med_12_ |
| ESTHER : Ghosh_2020_Sci.Transl.Med_12_ |
| PubMedSearch : Ghosh_2020_Sci.Transl.Med_12_ |
| PubMedID: 33298560 |
| Title : Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing beta-oxidation of fatty acid in mice - Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 |
| Author(s) : Yao L , Cao B , Cheng Q , Cai W , Ye C , Liang J , Liu W , Tan L , Yan M , Li B , He J , Hwang SH , Zhang X , Wang C , Ai D , Hammock BD , Zhu Y |
| Ref : American Journal of Physiology Gastrointest Liver Physiol , 316 :G527 , 2019 |
| Abstract : Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 |
| ESTHER : Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 |
| PubMedSearch : Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 |
| PubMedID: 30789748 |
| Title : 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells - Liang_2019_ACS.Chem.Neurosci_10_4018 |
| Author(s) : Liang Z , Zhang B , Xu M , Morisseau C , Hwang SH , Hammock BD , Li QX |
| Ref : ACS Chem Neurosci , 10 :4018 , 2019 |
| Abstract : Liang_2019_ACS.Chem.Neurosci_10_4018 |
| ESTHER : Liang_2019_ACS.Chem.Neurosci_10_4018 |
| PubMedSearch : Liang_2019_ACS.Chem.Neurosci_10_4018 |
| PubMedID: 31378059 |
| Title : Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity - Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 |
| Author(s) : Hiesinger K , Wagner KM , Hammock BD , Proschak E , Hwang SH |
| Ref : Prostaglandins Other Lipid Mediat , 140 :31 , 2019 |
| Abstract : Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 |
| ESTHER : Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 |
| PubMedSearch : Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 |
| PubMedID: 30593866 |
| Title : In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea - Wan_2019_Front.Pharmacol_10_464 |
| Author(s) : Wan D , Yang J , McReynolds CB , Barnych B , Wagner KM , Morisseau C , Hwang SH , Sun J , Blocher R , Hammock BD |
| Ref : Front Pharmacol , 10 :464 , 2019 |
| Abstract : Wan_2019_Front.Pharmacol_10_464 |
| ESTHER : Wan_2019_Front.Pharmacol_10_464 |
| PubMedSearch : Wan_2019_Front.Pharmacol_10_464 |
| PubMedID: 31143115 |
| Title : Inhibition of Pancreatic Carcinoma Growth Through Enhancing omega-3 Epoxy Polyunsaturated Fatty Acid Profile by Inhibition of Soluble Epoxide Hydrolase - Xia_2019_Anticancer.Res_39_3651 |
| Author(s) : Xia R , Sun L , Liao J , Li H , You X , Xu D , Yang J , Hwang SH , Jones RD , Hammock B , Yang GY |
| Ref : Anticancer Research , 39 :3651 , 2019 |
| Abstract : Xia_2019_Anticancer.Res_39_3651 |
| ESTHER : Xia_2019_Anticancer.Res_39_3651 |
| PubMedSearch : Xia_2019_Anticancer.Res_39_3651 |
| PubMedID: 31262891 |
| Title : Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation - Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 |
| Author(s) : Ma M , Ren Q , Yang J , Zhang K , Xiong Z , Ishima T , Pu Y , Hwang SH , Toyoshima M , Iwayama Y , Hisano Y , Yoshikawa T , Hammock BD , Hashimoto K |
| Ref : Proc Natl Acad Sci U S A , 116 :7083 , 2019 |
| Abstract : Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 |
| ESTHER : Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 |
| PubMedSearch : Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 |
| PubMedID: 30890645 |
| Title : Suppression of chemotherapy-induced cytokine\/lipid mediator surge and ovarian cancer by a dual COX-2\/sEH inhibitor - Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 |
| Author(s) : Gartung A , Yang J , Sukhatme VP , Bielenberg DR , Fernandes D , Chang J , Schmidt BA , Hwang SH , Zurakowski D , Huang S , Kieran MW , Hammock BD , Panigrahy D |
| Ref : Proc Natl Acad Sci U S A , 116 :1698 , 2019 |
| Abstract : Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 |
| ESTHER : Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 |
| PubMedSearch : Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 |
| PubMedID: 30647111 |
| Title : Effect Of Dual sEH\/COX-2 Inhibition on Allergen-Induced Airway Inflammation - Dileepan_2019_Front.Pharmacol_10_1118 |
| Author(s) : Dileepan M , Rastle-Simpson S , Greenberg Y , Wijesinghe DS , Kumar NG , Yang J , Hwang SH , Hammock BD , Sriramarao P , Rao SP |
| Ref : Front Pharmacol , 10 :1118 , 2019 |
| Abstract : Dileepan_2019_Front.Pharmacol_10_1118 |
| ESTHER : Dileepan_2019_Front.Pharmacol_10_1118 |
| PubMedSearch : Dileepan_2019_Front.Pharmacol_10_1118 |
| PubMedID: 31611798 |
| Title : Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK - Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 |
| Author(s) : Luo Y , Wu MY , Deng BQ , Huang J , Hwang SH , Li MY , Zhou CY , Zhang QY , Yu HB , Zhao DK , Zhang G , Qin L , Peng A , Hammock BD , Liu JY |
| Ref : Proc Natl Acad Sci U S A , 116 :5154 , 2019 |
| Abstract : Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 |
| ESTHER : Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 |
| PubMedSearch : Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 |
| PubMedID: 30804206 |
| Title : Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis - McReynolds_2019_Front.Pharmacol_10_533 |
| Author(s) : McReynolds CB , Hwang SH , Yang J , Wan D , Wagner K , Morisseau C , Li D , Schmidt WK , Hammock BD |
| Ref : Front Pharmacol , 10 :533 , 2019 |
| Abstract : McReynolds_2019_Front.Pharmacol_10_533 |
| ESTHER : McReynolds_2019_Front.Pharmacol_10_533 |
| PubMedSearch : McReynolds_2019_Front.Pharmacol_10_533 |
| PubMedID: 31214021 |
| Title : Design and Potency of Dual Soluble Epoxide Hydrolase\/Fatty Acid Amide Hydrolase Inhibitors - Kodani_2018_ACS.Omega_3_14076 |
| Author(s) : Kodani SD , Wan D , Wagner KM , Hwang SH , Morisseau C , Hammock BD |
| Ref : ACS Omega , 3 :14076 , 2018 |
| Abstract : Kodani_2018_ACS.Omega_3_14076 |
| ESTHER : Kodani_2018_ACS.Omega_3_14076 |
| PubMedSearch : Kodani_2018_ACS.Omega_3_14076 |
| PubMedID: 30411058 |
| Title : Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula - Kala_2018_Physiol.Res_67_401 |
| Author(s) : Kala P , Sedlakova L , Skaroupkova P , Kopkan L , Vanourkova Z , Taborsky M , Nishiyama A , Hwang SH , Hammock BD , Sadowski J , Melenovsky V , Imig JD , Cervenka L |
| Ref : Physiol Res , 67 :401 , 2018 |
| Abstract : Kala_2018_Physiol.Res_67_401 |
| ESTHER : Kala_2018_Physiol.Res_67_401 |
| PubMedSearch : Kala_2018_Physiol.Res_67_401 |
| PubMedID: 29527914 |
| Title : Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5\/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease - Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| Author(s) : Certikova Chabova V , Kujal P , Skaroupkova P , Varnourkova Z , Vackova S , Huskova Z , Kikerlova S , Sadowski J , Kompanowska-Jezierska E , Baranowska I , Hwang SH , Hammock BD , Imig JD , Tesar V , Cervenka L |
| Ref : Kidney Blood Press Res , 43 :329 , 2018 |
| Abstract : Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| ESTHER : Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| PubMedSearch : Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| PubMedID: 29529602 |
| Title : Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation - Bastan_2018_J.Leukoc.Biol_104_109 |
| Author(s) : Bastan I , Ge XN , Dileepan M , Greenberg YG , Guedes AG , Hwang SH , Hammock BD , Washabau RJ , Rao SP , Sriramarao P |
| Ref : J Leukoc Biol , 104 :109 , 2018 |
| Abstract : Bastan_2018_J.Leukoc.Biol_104_109 |
| ESTHER : Bastan_2018_J.Leukoc.Biol_104_109 |
| PubMedSearch : Bastan_2018_J.Leukoc.Biol_104_109 |
| PubMedID: 29345370 |
| Title : Soluble epoxide hydrolase inhibitor, APAU, protects dopaminergic neurons against rotenone induced neurotoxicity: Implications for Parkinson's disease - Lakkappa_2018_Neurotoxicol_70_135 |
| Author(s) : Lakkappa N , Krishnamurthy PT , M DP , Hammock BD , Hwang SH |
| Ref : Neurotoxicology , 70 :135 , 2018 |
| Abstract : Lakkappa_2018_Neurotoxicol_70_135 |
| ESTHER : Lakkappa_2018_Neurotoxicol_70_135 |
| PubMedSearch : Lakkappa_2018_Neurotoxicol_70_135 |
| PubMedID: 30472438 |
| Title : Orally Available Soluble Epoxide Hydrolase\/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain - Blocher_2018_J.Med.Chem_61_3541 |
| Author(s) : Blocher R , Wagner KM , Gopireddy RR , Harris TR , Wu H , Barnych B , Hwang SH , Xiang YK , Proschak E , Morisseau C , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 61 :3541 , 2018 |
| Abstract : Blocher_2018_J.Med.Chem_61_3541 |
| ESTHER : Blocher_2018_J.Med.Chem_61_3541 |
| PubMedSearch : Blocher_2018_J.Med.Chem_61_3541 |
| PubMedID: 29614224 |
| Title : Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase - Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
| Author(s) : Kodani SD , Bhakta S , Hwang SH , Pakhomova S , Newcomer ME , Morisseau C , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :762 , 2018 |
| Abstract : Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
| ESTHER : Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
| PubMedSearch : Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
| PubMedID: 29366648 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS\/MS method development - Lakkappa_2018_J.Pharm.Biomed.Anal_149_457 |
| Author(s) : Lakkappa N , Krishnamurthy PT , Yamjala K , Hwang SH , Hammock BD , Babu B |
| Ref : J Pharm Biomed Anal , 149 :457 , 2018 |
| Abstract : Lakkappa_2018_J.Pharm.Biomed.Anal_149_457 |
| ESTHER : Lakkappa_2018_J.Pharm.Biomed.Anal_149_457 |
| PubMedSearch : Lakkappa_2018_J.Pharm.Biomed.Anal_149_457 |
| PubMedID: 29169114 |
| Title : COX-2\/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin - Wang_2018_Mol.Cancer.Ther_17_474 |
| Author(s) : Wang F , Zhang H , Ma AH , Yu W , Zimmermann M , Yang J , Hwang SH , Zhu D , Lin TY , Malfatti M , Turteltaub KW , Henderson PT , Airhart S , Hammock BD , Yuan J , de Vere White RW , Pan CX |
| Ref : Mol Cancer Ther , 17 :474 , 2018 |
| Abstract : Wang_2018_Mol.Cancer.Ther_17_474 |
| ESTHER : Wang_2018_Mol.Cancer.Ther_17_474 |
| PubMedSearch : Wang_2018_Mol.Cancer.Ther_17_474 |
| PubMedID: 29284644 |
| Title : Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis - Guedes_2018_J.Vet.Pharmacol.Ther_41_230 |
| Author(s) : Guedes AGP , Aristizabal F , Sole A , Adedeji A , Brosnan R , Knych H , Yang J , Hwang SH , Morisseau C , Hammock BD |
| Ref : J Vet Pharmacol Ther , 41 :230 , 2018 |
| Abstract : Guedes_2018_J.Vet.Pharmacol.Ther_41_230 |
| ESTHER : Guedes_2018_J.Vet.Pharmacol.Ther_41_230 |
| PubMedSearch : Guedes_2018_J.Vet.Pharmacol.Ther_41_230 |
| PubMedID: 29067696 |
| Title : Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis - Guedes_2017_Equine.Vet.J_49_345 |
| Author(s) : Guedes A , Galuppo L , Hood D , Hwang SH , Morisseau C , Hammock BD |
| Ref : Equine Vet J , 49 :345 , 2017 |
| Abstract : Guedes_2017_Equine.Vet.J_49_345 |
| ESTHER : Guedes_2017_Equine.Vet.J_49_345 |
| PubMedSearch : Guedes_2017_Equine.Vet.J_49_345 |
| PubMedID: 27338788 |
| Title : Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats - Islam_2017_Cardiovasc.Ther_35_ |
| Author(s) : Islam O , Patil P , Goswami SK , Razdan R , Inamdar MN , Rizwan M , Mathew J , Inceoglu B , Stephen Lee KS , Hwang SH , Hammock BD |
| Ref : Cardiovasc Ther , 35 : , 2017 |
| Abstract : Islam_2017_Cardiovasc.Ther_35_ |
| ESTHER : Islam_2017_Cardiovasc.Ther_35_ |
| PubMedSearch : Islam_2017_Cardiovasc.Ther_35_ |
| PubMedID: 28296232 |
| Title : Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula - Cervenka_2015_Physiol.Res_64_857 |
| Author(s) : Cervenka L , Melenovsky V , Huskova Z , Sporkova A , Burgelova M , Skaroupkova P , Hwang SH , Hammock BD , Imig JD , Sadowski J |
| Ref : Physiol Res , 64 :857 , 2015 |
| Abstract : Cervenka_2015_Physiol.Res_64_857 |
| ESTHER : Cervenka_2015_Physiol.Res_64_857 |
| PubMedSearch : Cervenka_2015_Physiol.Res_64_857 |
| PubMedID: 26047375 |
| Title : In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors - Liu_2015_Biochem.Pharmacol_98_718 |
| Author(s) : Liu JY , Tsai HJ , Morisseau C , Lango J , Hwang SH , Watanabe T , Kim IH , Hammock BD |
| Ref : Biochemical Pharmacology , 98 :718 , 2015 |
| Abstract : Liu_2015_Biochem.Pharmacol_98_718 |
| ESTHER : Liu_2015_Biochem.Pharmacol_98_718 |
| PubMedSearch : Liu_2015_Biochem.Pharmacol_98_718 |
| PubMedID: 26494425 |
| Title : Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides - Lopez-Vicario_2015_Proc.Natl.Acad.Sci.U.S.A_112_536 |
| Author(s) : Lopez-Vicario C , Alcaraz-Quiles J , Garcia-Alonso V , Rius B , Hwang SH , Titos E , Lopategi A , Hammock BD , Arroyo V , Claria J |
| Ref : Proc Natl Acad Sci U S A , 112 :536 , 2015 |
| Abstract : Lopez-Vicario_2015_Proc.Natl.Acad.Sci.U.S.A_112_536 |
| ESTHER : Lopez-Vicario_2015_Proc.Natl.Acad.Sci.U.S.A_112_536 |
| PubMedSearch : Lopez-Vicario_2015_Proc.Natl.Acad.Sci.U.S.A_112_536 |
| PubMedID: 25550510 |
| Title : Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern - Ostermann_2015_Prostaglandins.Other.Lipid.Mediat_121_131 |
| Author(s) : Ostermann AI , Herbers J , Willenberg I , Chen R , Hwang SH , Greite R , Morisseau C , Gueler F , Hammock BD , Schebb NH |
| Ref : Prostaglandins Other Lipid Mediat , 121 :131 , 2015 |
| Abstract : Ostermann_2015_Prostaglandins.Other.Lipid.Mediat_121_131 |
| ESTHER : Ostermann_2015_Prostaglandins.Other.Lipid.Mediat_121_131 |
| PubMedSearch : Ostermann_2015_Prostaglandins.Other.Lipid.Mediat_121_131 |
| PubMedID: 26117215 |
| Title : Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy - Lee_2014_J.Med.Chem_57_7016 |
| Author(s) : Lee KS , Liu JY , Wagner KM , Pakhomova S , Dong H , Morisseau C , Fu SH , Yang J , Wang P , Ulu A , Mate CA , Nguyen LV , Hwang SH , Edin ML , Mara AA , Wulff H , Newcomer ME , Zeldin DC , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 57 :7016 , 2014 |
| Abstract : Lee_2014_J.Med.Chem_57_7016 |
| ESTHER : Lee_2014_J.Med.Chem_57_7016 |
| PubMedSearch : Lee_2014_J.Med.Chem_57_7016 |
| PubMedID: 25079952 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy - Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| Author(s) : Kim J , Yoon SP , Toews ML , Imig JD , Hwang SH , Hammock BD , Padanilam BJ |
| Ref : American Journal of Physiology Renal Physiol , :ajprenal 00531 2014 , 2014 |
| Abstract : Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| ESTHER : Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| PubMedSearch : Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| PubMedID: 25377915 |
| Title : Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis - Zhang_2014_Proc.Natl.Acad.Sci.U.S.A_111_11127 |
| Author(s) : Zhang G , Panigrahy D , Hwang SH , Yang J , Mahakian LM , Wettersten HI , Liu JY , Wang Y , Ingham ES , Tam S , Kieran MW , Weiss RH , Ferrara KW , Hammock BD |
| Ref : Proc Natl Acad Sci U S A , 111 :11127 , 2014 |
| Abstract : Zhang_2014_Proc.Natl.Acad.Sci.U.S.A_111_11127 |
| ESTHER : Zhang_2014_Proc.Natl.Acad.Sci.U.S.A_111_11127 |
| PubMedSearch : Zhang_2014_Proc.Natl.Acad.Sci.U.S.A_111_11127 |
| PubMedID: 25024195 |
| Title : Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB - Wecksler_2014_Anticancer.Drugs_25_433 |
| Author(s) : Wecksler AT , Hwang SH , Wettersten HI , Gilda JE , Patton A , Leon LJ , Carraway KL, 3rd , Gomes AV , Baar K , Weiss RH , Hammock BD |
| Ref : Anticancer Drugs , 25 :433 , 2014 |
| Abstract : Wecksler_2014_Anticancer.Drugs_25_433 |
| ESTHER : Wecksler_2014_Anticancer.Drugs_25_433 |
| PubMedSearch : Wecksler_2014_Anticancer.Drugs_25_433 |
| PubMedID: 24525589 |
| Title : Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system - Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| Author(s) : Varcabova S , Huskova Z , Kramer HJ , Hwang SH , Hammock BD , Imig JD , Kitada K , Cervenka L |
| Ref : Clinical & Experimental Pharmacology & Physiology , 40 :273 , 2013 |
| Abstract : Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| ESTHER : Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| PubMedSearch : Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| PubMedID: 23039246 |
| Title : Frster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase - Lee_2013_Anal.Biochem_434_259 |
| Author(s) : Lee KS , Morisseau C , Yang J , Wang P , Hwang SH , Hammock BD |
| Ref : Analytical Biochemistry , 434 :259 , 2013 |
| Abstract : Lee_2013_Anal.Biochem_434_259 |
| ESTHER : Lee_2013_Anal.Biochem_434_259 |
| PubMedSearch : Lee_2013_Anal.Biochem_434_259 |
| PubMedID: 23219719 |
| Title : Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides - Morisseau_2013_Bioorg.Med.Chem.Lett_23_3818 |
| Author(s) : Morisseau C , Pakhomova S , Hwang SH , Newcomer ME , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3818 , 2013 |
| Abstract : Morisseau_2013_Bioorg.Med.Chem.Lett_23_3818 |
| ESTHER : Morisseau_2013_Bioorg.Med.Chem.Lett_23_3818 |
| PubMedSearch : Morisseau_2013_Bioorg.Med.Chem.Lett_23_3818 |
| PubMedID: 23684894 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models - Liu_2013_Eur.J.Pharm.Sci_48_619 |
| Author(s) : Liu JY , Lin YP , Qiu H , Morisseau C , Rose TE , Hwang SH , Chiamvimonvat N , Hammock BD |
| Ref : Eur J Pharm Sci , 48 :619 , 2013 |
| Abstract : Liu_2013_Eur.J.Pharm.Sci_48_619 |
| ESTHER : Liu_2013_Eur.J.Pharm.Sci_48_619 |
| PubMedSearch : Liu_2013_Eur.J.Pharm.Sci_48_619 |
| PubMedID: 23291046 |
| Title : Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie - Poli_2013_Life.Sci_92_1145 |
| Author(s) : Poli G , Corda E , Martino PA , Dall'ara P , Bareggi SR , Bondiolotti G , Iulini B , Mazza M , Casalone C , Hwang SH , Hammock BD , Inceoglu B |
| Ref : Life Sciences , 92 :1145 , 2013 |
| Abstract : Poli_2013_Life.Sci_92_1145 |
| ESTHER : Poli_2013_Life.Sci_92_1145 |
| PubMedSearch : Poli_2013_Life.Sci_92_1145 |
| PubMedID: 23651659 |
| Title : Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors - Hwang_2013_Bioorg.Med.Chem.Lett_23_3732 |
| Author(s) : Hwang SH , Wecksler AT , Zhang G , Morisseau C , Nguyen LV , Fu SH , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3732 , 2013 |
| Abstract : Hwang_2013_Bioorg.Med.Chem.Lett_23_3732 |
| ESTHER : Hwang_2013_Bioorg.Med.Chem.Lett_23_3732 |
| PubMedSearch : Hwang_2013_Bioorg.Med.Chem.Lett_23_3732 |
| PubMedID: 23726028 |
| Title : Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke - Shaik_2013_Am.J.Physiol.Heart.Circ.Physiol_305_H1605 |
| Author(s) : Shaik JS , Ahmad M , Li W , Rose ME , Foley LM , Hitchens TK , Graham SH , Hwang SH , Hammock BD , Poloyac SM |
| Ref : American Journal of Physiology Heart Circ Physiol , 305 :H1605 , 2013 |
| Abstract : Shaik_2013_Am.J.Physiol.Heart.Circ.Physiol_305_H1605 |
| ESTHER : Shaik_2013_Am.J.Physiol.Heart.Circ.Physiol_305_H1605 |
| PubMedSearch : Shaik_2013_Am.J.Physiol.Heart.Circ.Physiol_305_H1605 |
| PubMedID: 24043255 |
| Title : Soluble Epoxide Hydrolase Inhibition Exhibits Antihypertensive Actions Independently of Nitric Oxide in Mice with Renovascular Hypertension - Kopkan_2012_Kidney.Blood.Press.Res_35_595 |
| Author(s) : Kopkan L , Huskova Z , Sporkova A , Varcabova S , Honetschlagerova Z , Hwang SH , Tsai HJ , Hammock BD , Imig JD , Kramer HJ , Burgelova M , Vojtiskova A , Kujal P , Vernerova Z , Cervenka L |
| Ref : Kidney Blood Press Res , 35 :595 , 2012 |
| Abstract : Kopkan_2012_Kidney.Blood.Press.Res_35_595 |
| ESTHER : Kopkan_2012_Kidney.Blood.Press.Res_35_595 |
| PubMedSearch : Kopkan_2012_Kidney.Blood.Press.Res_35_595 |
| PubMedID: 22948718 |
| Title : Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension - Neckar_2012_Clin.Sci.(Lond)_122_513 |
| Author(s) : Neckar J , Kopkan L , Huskova Z , Kolar F , Papousek F , Kramer HJ , Hwang SH , Hammock BD , Imig JD , Maly J , Netuka I , Ostadal B , Cervenka L |
| Ref : Clinical Science (Lond) , 122 :513 , 2012 |
| Abstract : Neckar_2012_Clin.Sci.(Lond)_122_513 |
| ESTHER : Neckar_2012_Clin.Sci.(Lond)_122_513 |
| PubMedSearch : Neckar_2012_Clin.Sci.(Lond)_122_513 |
| PubMedID: 22324471 |
| Title : Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats - Iyer_2012_Exp.Diabetes.Res_2012_758614 |
| Author(s) : Iyer A , Kauter K , Alam MA , Hwang SH , Morisseau C , Hammock BD , Brown L |
| Ref : Exp Diabetes Res , 2012 :758614 , 2012 |
| Abstract : Iyer_2012_Exp.Diabetes.Res_2012_758614 |
| ESTHER : Iyer_2012_Exp.Diabetes.Res_2012_758614 |
| PubMedSearch : Iyer_2012_Exp.Diabetes.Res_2012_758614 |
| PubMedID: 22007192 |
| Title : Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy - Inoue_2011_Cancer.Biol.Ther_12_827 |
| Author(s) : Inoue H , Hwang SH , Wecksler AT , Hammock BD , Weiss RH |
| Ref : Cancer Biol Ther , 12 :827 , 2011 |
| Abstract : Inoue_2011_Cancer.Biol.Ther_12_827 |
| ESTHER : Inoue_2011_Cancer.Biol.Ther_12_827 |
| PubMedSearch : Inoue_2011_Cancer.Biol.Ther_12_827 |
| PubMedID: 21878748 |
| Title : Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors - Schebb_2011_Anal.Bioanal.Chem_400_1359 |
| Author(s) : Schebb NH , Huby M , Morisseau C , Hwang SH , Hammock BD |
| Ref : Anal Bioanal Chem , 400 :1359 , 2011 |
| Abstract : Schebb_2011_Anal.Bioanal.Chem_400_1359 |
| ESTHER : Schebb_2011_Anal.Bioanal.Chem_400_1359 |
| PubMedSearch : Schebb_2011_Anal.Bioanal.Chem_400_1359 |
| PubMedID: 21479549 |
| Title : Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension - Honetschlagerova_2011_J.Physiol_589_207 |
| Author(s) : Honetschlagerova Z , Z ZH , Vanourkova Z , Sporkova A , Kramer HJ , Hwang SH , Tsai HJ , Hammock BD , Imig JD , Cervenka L , Kopkan L |
| Ref : The Journal of Physiology , 589 :207 , 2011 |
| Abstract : Honetschlagerova_2011_J.Physiol_589_207 |
| ESTHER : Honetschlagerova_2011_J.Physiol_589_207 |
| PubMedSearch : Honetschlagerova_2011_J.Physiol_589_207 |
| PubMedID: 21078594 |
| Title : Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase - Hwang_2011_J.Med.Chem_54_3037 |
| Author(s) : Hwang SH , Wagner KM , Morisseau C , Liu JY , Dong H , Wecksler AT , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 54 :3037 , 2011 |
| Abstract : Hwang_2011_J.Med.Chem_54_3037 |
| ESTHER : Hwang_2011_J.Med.Chem_54_3037 |
| PubMedSearch : Hwang_2011_J.Med.Chem_54_3037 |
| PubMedID: 21434686 |
| Title : Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model - Liu_2010_Biochem.Pharmacol_79_880 |
| Author(s) : Liu JY , Yang J , Inceoglu B , Qiu H , Ulu A , Hwang SH , Chiamvimonvat N , Hammock BD |
| Ref : Biochemical Pharmacology , 79 :880 , 2010 |
| Abstract : Liu_2010_Biochem.Pharmacol_79_880 |
| ESTHER : Liu_2010_Biochem.Pharmacol_79_880 |
| PubMedSearch : Liu_2010_Biochem.Pharmacol_79_880 |
| PubMedID: 19896470 |
| Title : Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis - Luo_2010_J.Pharmacol.Exp.Ther_334_430 |
| Author(s) : Luo P , Chang HH , Zhou Y , Zhang S , Hwang SH , Morisseau C , Wang CY , Inscho EW , Hammock BD , Wang MH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :430 , 2010 |
| Abstract : Luo_2010_J.Pharmacol.Exp.Ther_334_430 |
| ESTHER : Luo_2010_J.Pharmacol.Exp.Ther_334_430 |
| PubMedSearch : Luo_2010_J.Pharmacol.Exp.Ther_334_430 |
| PubMedID: 20439437 |
| Title : Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease - Jung_2010_PLoS.One_5_e11979 |
| Author(s) : Jung O , Jansen F , Mieth A , Barbosa-Sicard E , Pliquett RU , Babelova A , Morisseau C , Hwang SH , Tsai C , Hammock BD , Schaefer L , Geisslinger G , Amann K , Brandes RP |
| Ref : PLoS ONE , 5 :e11979 , 2010 |
| Abstract : Jung_2010_PLoS.One_5_e11979 |
| ESTHER : Jung_2010_PLoS.One_5_e11979 |
| PubMedSearch : Jung_2010_PLoS.One_5_e11979 |
| PubMedID: 20694143 |
| Title : Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury - Chaudhary_2010_J.Cardiovasc.Pharmacol_55_67 |
| Author(s) : Chaudhary KR , Abukhashim M , Hwang SH , Hammock BD , Seubert JM |
| Ref : J Cardiovasc Pharmacol , 55 :67 , 2010 |
| Abstract : Chaudhary_2010_J.Cardiovasc.Pharmacol_55_67 |
| ESTHER : Chaudhary_2010_J.Cardiovasc.Pharmacol_55_67 |
| PubMedSearch : Chaudhary_2010_J.Cardiovasc.Pharmacol_55_67 |
| PubMedID: 19834332 |
| Title : Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs - Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| Author(s) : Tsai HJ , Hwang SH , Morisseau C , Yang J , Jones PD , Kasagami T , Kim IH , Hammock BD |
| Ref : Eur J Pharm Sci , 40 :222 , 2010 |
| Abstract : Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| ESTHER : Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| PubMedSearch : Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| PubMedID: 20359531 |
| Title : Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches - Li_2009_J.Mol.Cell.Cardiol_47_835 |
| Author(s) : Li N , Liu JY , Timofeyev V , Qiu H , Hwang SH , Tuteja D , Lu L , Yang J , Mochida H , Low R , Hammock BD , Chiamvimonvat N |
| Ref : Journal of Molecular & Cellular Cardiology , 47 :835 , 2009 |
| Abstract : Li_2009_J.Mol.Cell.Cardiol_47_835 |
| ESTHER : Li_2009_J.Mol.Cell.Cardiol_47_835 |
| PubMedSearch : Li_2009_J.Mol.Cell.Cardiol_47_835 |
| PubMedID: 19716829 |
| Title : Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation - Liu_2009_Br.J.Pharmacol_156_284 |
| Author(s) : Liu JY , Tsai HJ , Hwang SH , Jones PD , Morisseau C , Hammock BD |
| Ref : British Journal of Pharmacology , 156 :284 , 2009 |
| Abstract : Liu_2009_Br.J.Pharmacol_156_284 |
| ESTHER : Liu_2009_Br.J.Pharmacol_156_284 |
| PubMedSearch : Liu_2009_Br.J.Pharmacol_156_284 |
| PubMedID: 19154430 |
| Title : Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo - Liu_2009_Mol.Cancer.Ther_8_2193 |
| Author(s) : Liu JY , Park SH , Morisseau C , Hwang SH , Hammock BD , Weiss RH |
| Ref : Mol Cancer Ther , 8 :2193 , 2009 |
| Abstract : Liu_2009_Mol.Cancer.Ther_8_2193 |
| ESTHER : Liu_2009_Mol.Cancer.Ther_8_2193 |
| PubMedSearch : Liu_2009_Mol.Cancer.Ther_8_2193 |
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| Title : Orally bioavailable potent soluble epoxide hydrolase inhibitors - Hwang_2007_J.Med.Chem_50_3825 |
| Author(s) : Hwang SH , Tsai HJ , Liu JY , Morisseau C , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 50 :3825 , 2007 |
| Abstract : Hwang_2007_J.Med.Chem_50_3825 |
| ESTHER : Hwang_2007_J.Med.Chem_50_3825 |
| PubMedSearch : Hwang_2007_J.Med.Chem_50_3825 |
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| Title : Synthesis and biological evaluation of 1-(4-[18F]fluorobenzyl)-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine for in vivo studies of acetylcholinesterase - Lee_2000_Nucl.Med.Biol_27_741 |
| Author(s) : Lee SY , Choe YS , Sugimoto H , Kim SE , Hwang SH , Lee K , Choi Y , Lee J , Kim B |
| Ref : Nucl Med Biol , 27 :741 , 2000 |
| Abstract : Lee_2000_Nucl.Med.Biol_27_741 |
| ESTHER : Lee_2000_Nucl.Med.Biol_27_741 |
| PubMedSearch : Lee_2000_Nucl.Med.Biol_27_741 |
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