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Author Report for: Humphries SE

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    Title: PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry
    Casas JP, Ninio E, Panayiotou A, Palmen J, Cooper JA, Ricketts SL, Sofat R, Nicolaides AN, Corsetti JP and Talmud PJ <16 more author(s)>
    Ref: Circulation, 121:2284, 2010 : PubMed


    Title: Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding
    Dorfmeister B, Zeng WW, Dichlberger A, Nilsson SK, Schaap FG, Hubacek JA, Merkel M, Cooper JA, Lookene A and Talmud PJ <13 more author(s)>
    Ref: Arterioscler Thromb Vasc Biol, 28:1866, 2008 : PubMed


    Title: Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men
    Humphries SE, Cooper JA, Talmud PJ, Miller GJ
    Ref: Clinical Chemistry, 53:8, 2007 : PubMed


    Title: The lipoprotein lipase gene serine 447 stop variant influences hypertension-induced left ventricular hypertrophy and risk of coronary heart disease
    Talmud PJ, Flavell DM, Alfakih K, Cooper JA, Balmforth AJ, Sivananthan M, Montgomery HE, Hall AS, Humphries SE
    Ref: Clinical Science (Lond), 112:617, 2007 : PubMed


    Title: Lipoprotein-associated phospholipase A2 A379V variant is associated with body composition changes in response to exercise training
    Wootton PT, Flavell DM, Montgomery HE, World M, Humphries SE, Talmud PJ
    Ref: Nutr Metab Cardiovasc Dis, 17:24, 2007 : PubMed


    Title: Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth
    Flavell DM, Wootton PT, Myerson SG, World MJ, Pennell DJ, Humphries SE, Talmud PJ, Montgomery HE
    Ref: J Mol Med (Berl), 84:126, 2006 : PubMed


    Title: Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men
    Waterworth DM, Jansen H, Nicaud V, Humphries SE, Talmud PJ
    Ref: Biochimica & Biophysica Acta, 1740:375, 2005 : PubMed


    Title: Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe
    Abuzeid AM, Hawe E, Humphries SE, Talmud PJ
    Ref: Atherosclerosis, 168:283, 2003 : PubMed


    Title: Genetic and environmental determinants of plasma high density lipoprotein cholesterol and apolipoprotein AI concentrations in healthy middle-aged men
    Talmud PJ, Hawe E, Robertson K, Miller GJ, Miller NE, Humphries SE
    Ref: Ann Hum Genet, 66:111, 2002 : PubMed


    Title: Polymorphisms in the lipoprotein lipase and hepatic lipase genes and plasma lipid values in the Czech population
    Hubacek JA, Waterworth DM, Pitha J, Humphries SE, Talmud PJ, Poledne R
    Ref: Physiol Res, 50:345, 2001 : PubMed


    Title: Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: the European Atherosclerosis Research Study (EARS)
    Humphries SE, Nicaud V, Margalef J, Tiret L, Talmud PJ
    Ref: Arterioscler Thromb Vasc Biol, 18:526, 1998 : PubMed


    Title: LPL promoter -93T/G transition influences fasting and postprandial plasma triglycerides response in African-Americans and Hispanics
    Talmud PJ, Hall S, Holleran S, Ramakrishnan R, Ginsberg HN, Humphries SE
    Ref: J Lipid Res, 39:1189, 1998 : PubMed


    Title: Common variation in the lipoprotein lipase gene: effects on plasma lipids and risk of atherosclerosis
    Fisher RM, Humphries SE, Talmud PJ
    Ref: Atherosclerosis, 135:145, 1997 : PubMed


    Title: Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein cholesterol concentrations: studies in the fasting and postprandial states: the European Atherosclerosis Research Studies
    Gerdes C, Fisher RM, Nicaud V, Boer J, Humphries SE, Talmud PJ, Faergeman O
    Ref: Circulation, 96:733, 1997 : PubMed


    Title: A common mutation in the lipoprotein lipase gene promoter, -93T/G, is associated with lower plasma triglyceride levels and increased promoter activity in vitro
    Hall S, Chu G, Miller G, Cruickshank K, Cooper JA, Humphries SE, Talmud PJ
    Ref: Arterioscler Thromb Vasc Biol, 17:1969, 1997 : PubMed


    Title: Familial lipoprotein lipase (LPL) deficiency: a catalogue of LPL gene mutations identified in 20 patients from the UK, Sweden, and Italy
    Mailly F, Palmen J, Muller DP, Gibbs T, Lloyd J, Brunzell J, Durrington P, Mitropoulos K, Betteridge J and Talmud PJ <4 more author(s)>
    Ref: Hum Mutat, 10:465, 1997 : PubMed


    Title: Variation at the lipoprotein lipase and apolipoprotein AI-CIII gene loci are associated with fasting lipid and lipoprotein traits in a population sample from Iceland: interaction between genotype, gender, and smoking status
    Peacock RE, Temple A, Gudnason V, Rosseneu M, Humphries SE
    Ref: Genet Epidemiol, 14:265, 1997 : PubMed


    Title: Genetic factors affecting the consistency and magnitude of changes in plasma cholesterol in response to dietary challenge
    Humphries SE, Talmud PJ, Cox C, Sutherland W, Mann J
    Ref: Qjm, 89:671, 1996 : PubMed


    Title: Association between the LPL-D9N mutation in the lipoprotein lipase gene and plasma lipid traits in myocardial infarction survivors from the ECTIM Study
    Mailly F, Fisher RM, Nicaud V, Luong LA, Evans AE, Marques-Vidal P, Luc G, Arveiler D, Bard JM and Humphries SE <2 more author(s)>
    Ref: Atherosclerosis, 122:21, 1996 : PubMed


    Title: Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia
    de Bruin TW, Mailly F, van Barlingen HH, Fisher R, Castro Cabezas M, Talmud P, Dallinga-Thie GM, Humphries SE
    Ref: European Journal of Clinical Investigation, 26:631, 1996 : PubMed


    Title: Interaction of the lipoprotein lipase asparagine 291-->serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults
    Fisher RM, Mailly F, Peacock RE, Hamsten A, Seed M, Yudkin JS, Beisiegel U, Feussner G, Miller G and et al. <1 more author(s)>
    Ref: J Lipid Res, 36:2104, 1995 : PubMed


    Title: Associations of genotypes at the apolipoprotein AI-CIII-AIV, apolipoprotein B and lipoprotein lipase gene loci with coronary atherosclerosis and high density lipoprotein subclasses
    Peacock RE, Hamsten A, Johansson J, Nilsson-Ehle P, Humphries SE
    Ref: Clin Genet, 46:273, 1994 : PubMed


    Title: Associations between lipoprotein lipase gene polymorphisms and plasma correlations of lipids, lipoproteins and lipase activities in young myocardial infarction survivors and age-matched healthy individuals from Sweden
    Peacock RE, Hamsten A, Nilsson-Ehle P, Humphries SE
    Ref: Atherosclerosis, 97:171, 1992 : PubMed


    Title: A study of the structure of the gene for lecithin: cholesterol acyltransferase in four unrelated individuals with familial lecithin: cholesterol acyltransferase deficiency
    Humphries SE, Chaves ME, Tata F, Lima VL, Owen JS, Borysiewicz LK, Catapano A, Vergani C, Gjone E and et al. <1 more author(s)>
    Ref: Clinical Science (Lond), 74:91, 1988 : PubMed


    Title: The structural gene for lecithin:cholesterol acyl transferase (LCAT) maps to 16q22
    Azoulay M, Henry I, Tata F, Weil D, Grzeschik KH, Chaves ME, McIntyre N, Williamson R, Humphries SE, Junien C
    Ref: Ann Hum Genet, 51:129, 1987 : PubMed


    Title: The isolation and characterisation of cDNA and genomic clones for human lecithin: cholesterol acyltransferase
    Tata F, Chaves ME, Markham AF, Scrace GD, Waterfield MD, McIntyre N, Williamson R, Humphries SE
    Ref: Biochimica & Biophysica Acta, 910:142, 1987 : PubMed


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