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Title : Esterases with an introduced amidase-like hydrogen bond in the transition state have increased amidase specificity - |
Author(s) : Syren PO , Hendil-Forssell P , Aumailley L , Besenmatter W , Gounine F , Svendsen A , Martinelle M , Hult K |
Ref : Chembiochem , 13 :645 , 2012 |
PubMedID: 22378481 |
Title : Rational redesign of Candida antarctica lipase B for the ring opening polymerization of D,D-lactide - Takwa_2011_Chem.Commun.(Camb)_47_7392 |
Author(s) : Takwa M , Larsen MW , Hult K , Martinelle M |
Ref : Chem Commun (Camb) , 47 :7392 , 2011 |
Abstract : Takwa_2011_Chem.Commun.(Camb)_47_7392 |
ESTHER : Takwa_2011_Chem.Commun.(Camb)_47_7392 |
PubMedSearch : Takwa_2011_Chem.Commun.(Camb)_47_7392 |
PubMedID: 21607247 |
Title : Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols - Engstrom_2011_Org.Biomol.Chem_9_81 |
Author(s) : Engstrom K , Vallin M , Syren PO , Hult K , Backvall JE |
Ref : Org Biomol Chem , 9 :81 , 2011 |
Abstract : Engstrom_2011_Org.Biomol.Chem_9_81 |
ESTHER : Engstrom_2011_Org.Biomol.Chem_9_81 |
PubMedSearch : Engstrom_2011_Org.Biomol.Chem_9_81 |
PubMedID: 21082131 |
Title : Substrate conformations set the rate of enzymatic acrylation by lipases - Syren_2010_Chembiochem_11_802 |
Author(s) : Syren PO , Hult K |
Ref : Chembiochem , 11 :802 , 2010 |
Abstract : Syren_2010_Chembiochem_11_802 |
ESTHER : Syren_2010_Chembiochem_11_802 |
PubMedSearch : Syren_2010_Chembiochem_11_802 |
PubMedID: 20301160 |
Gene_locus related to this paper: humin-cut |
Title : Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: a thermodynamic analysis of enantioselectivity - Vallin_2010_Chembiochem_11_411 |
Author(s) : Vallin M , Syren PO , Hult K |
Ref : Chembiochem , 11 :411 , 2010 |
Abstract : Vallin_2010_Chembiochem_11_411 |
ESTHER : Vallin_2010_Chembiochem_11_411 |
PubMedSearch : Vallin_2010_Chembiochem_11_411 |
PubMedID: 20049759 |
Gene_locus related to this paper: canar-LipB |
Title : Suppression of water as a nucleophile in Candida antarctica lipase B catalysis - Larsen_2010_Chembiochem_11_796 |
Author(s) : Larsen MW , Zielinska DF , Martinelle M , Hidalgo A , Jensen LJ , Bornscheuer UT , Hult K |
Ref : Chembiochem , 11 :796 , 2010 |
Abstract : Larsen_2010_Chembiochem_11_796 |
ESTHER : Larsen_2010_Chembiochem_11_796 |
PubMedSearch : Larsen_2010_Chembiochem_11_796 |
PubMedID: 20235107 |
Gene_locus related to this paper: canan-lipasA |
Title : Lactone size dependent reactivity in Candida antarctica lipase B: a molecular dynamics and docking study - Veld_2009_Chembiochem_10_1330 |
Author(s) : Veld MA , Fransson L , Palmans AR , Meijer EW , Hult K |
Ref : Chembiochem , 10 :1330 , 2009 |
Abstract : Veld_2009_Chembiochem_10_1330 |
ESTHER : Veld_2009_Chembiochem_10_1330 |
PubMedSearch : Veld_2009_Chembiochem_10_1330 |
PubMedID: 19425034 |
Title : Systematic comparison of HEA and HEMA as initiators in enzymatic ring-opening polymerizations - Xiao_2009_Macromol.Biosci_9_713 |
Author(s) : Xiao Y , Takwa M , Hult K , Koning CE , Heise A , Martinelle M |
Ref : Macromol Biosci , 9 :713 , 2009 |
Abstract : Xiao_2009_Macromol.Biosci_9_713 |
ESTHER : Xiao_2009_Macromol.Biosci_9_713 |
PubMedSearch : Xiao_2009_Macromol.Biosci_9_713 |
PubMedID: 19242919 |
Gene_locus related to this paper: canar-LipB |
Title : Understanding promiscuous amidase activity of an esterase from Bacillus subtilis - |
Author(s) : Kourist R , Bartsch S , Fransson L , Hult K , Bornscheuer UT |
Ref : Chembiochem , 9 :67 , 2008 |
PubMedID: 18022973 |
Gene_locus related to this paper: bacsu-pnbae , canar-LipB |
Title : Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification - Takwa_2008_Biomacromolecules_9_704 |
Author(s) : Takwa M , Xiao Y , Simpson N , Malmstrom E , Hult K , Koning CE , Heise A , Martinelle M |
Ref : Biomacromolecules , 9 :704 , 2008 |
Abstract : Takwa_2008_Biomacromolecules_9_704 |
ESTHER : Takwa_2008_Biomacromolecules_9_704 |
PubMedSearch : Takwa_2008_Biomacromolecules_9_704 |
PubMedID: 18198845 |
Gene_locus related to this paper: canar-LipB |
Title : Direct epoxidation in Candida antarctica lipase B studied by experiment and theory - Svedendahl_2008_Chembiochem_9_2443 |
Author(s) : Svedendahl M , Carlqvist P , Branneby C , Allner O , Frise A , Hult K , Berglund P , Brinck T |
Ref : Chembiochem , 9 :2443 , 2008 |
Abstract : Svedendahl_2008_Chembiochem_9_2443 |
ESTHER : Svedendahl_2008_Chembiochem_9_2443 |
PubMedSearch : Svedendahl_2008_Chembiochem_9_2443 |
PubMedID: 18837059 |
Title : Expression of Candida antarctica lipase B in Pichia pastoris and various Escherichia coli systems - Larsen_2008_Protein.Expr.Purif_62_90 |
Author(s) : Larsen MW , Bornscheuer UT , Hult K |
Ref : Protein Expr Purif , 62 :90 , 2008 |
Abstract : Larsen_2008_Protein.Expr.Purif_62_90 |
ESTHER : Larsen_2008_Protein.Expr.Purif_62_90 |
PubMedSearch : Larsen_2008_Protein.Expr.Purif_62_90 |
PubMedID: 18725303 |
Title : A water molecule in the stereospecificity pocket of Candida antarctica lipase B enhances enantioselectivity towards pentan-2-ol - Leonard_2007_Chembiochem_8_662 |
Author(s) : Leonard V , Fransson L , Lamare S , Hult K , Graber M |
Ref : Chembiochem , 8 :662 , 2007 |
Abstract : Leonard_2007_Chembiochem_8_662 |
ESTHER : Leonard_2007_Chembiochem_8_662 |
PubMedSearch : Leonard_2007_Chembiochem_8_662 |
PubMedID: 17328021 |
Title : Highly enantioselective kinetic resolution of two tertiary alcohols using mutants of an esterase from Bacillus subtilis - Heinze_2007_Protein.Eng.Des.Sel_20_125 |
Author(s) : Heinze B , Kourist R , Fransson L , Hult K , Bornscheuer UT |
Ref : Protein Engineering Des Sel , 20 :125 , 2007 |
Abstract : Heinze_2007_Protein.Eng.Des.Sel_20_125 |
ESTHER : Heinze_2007_Protein.Eng.Des.Sel_20_125 |
PubMedSearch : Heinze_2007_Protein.Eng.Des.Sel_20_125 |
PubMedID: 17309898 |
Gene_locus related to this paper: bacsu-pnbae |
Title : Solvent as a competitive inhibitor for Candida antarctica lipase B - Graber_2007_Biochim.Biophys.Acta_1774_1052 |
Author(s) : Graber M , Irague R , Rosenfeld E , Lamare S , Franson L , Hult K |
Ref : Biochimica & Biophysica Acta , 1774 :1052 , 2007 |
Abstract : Graber_2007_Biochim.Biophys.Acta_1774_1052 |
ESTHER : Graber_2007_Biochim.Biophys.Acta_1774_1052 |
PubMedSearch : Graber_2007_Biochim.Biophys.Acta_1774_1052 |
PubMedID: 17602903 |
Title : Molecular basis for the enhanced lipase-catalyzed N-acylation of 1-phenylethanamine with methoxyacetate - Cammenberg_2006_Chembiochem_7_1745 |
Author(s) : Cammenberg M , Hult K , Park S |
Ref : Chembiochem , 7 :1745 , 2006 |
Abstract : Cammenberg_2006_Chembiochem_7_1745 |
ESTHER : Cammenberg_2006_Chembiochem_7_1745 |
PubMedSearch : Cammenberg_2006_Chembiochem_7_1745 |
PubMedID: 16991170 |
Title : Molecular basis of perhydrolase activity in serine hydrolases - |
Author(s) : Bernhardt P , Hult K , Kazlauskas RJ |
Ref : Angew Chem Int Ed Engl , 44 :2742 , 2005 |
PubMedID: 15803517 |
Title : Creating space for large secondary alcohols by rational redesign of Candida antarctica lipase B - Magnusson_2005_Chembiochem_6_1051 |
Author(s) : Magnusson AO , Rotticci-Mulder JC , Santagostino A , Hult K |
Ref : Chembiochem , 6 :1051 , 2005 |
Abstract : Magnusson_2005_Chembiochem_6_1051 |
ESTHER : Magnusson_2005_Chembiochem_6_1051 |
PubMedSearch : Magnusson_2005_Chembiochem_6_1051 |
PubMedID: 15883973 |
Gene_locus related to this paper: canar-LipB |
Title : Exploring the active-site of a rationally redesigned lipase for catalysis of Michael-type additions - Carlqvist_2005_Chembiochem_6_331 |
Author(s) : Carlqvist P , Svedendahl M , Branneby C , Hult K , Brinck T , Berglund P |
Ref : Chembiochem , 6 :331 , 2005 |
Abstract : Carlqvist_2005_Chembiochem_6_331 |
ESTHER : Carlqvist_2005_Chembiochem_6_331 |
PubMedSearch : Carlqvist_2005_Chembiochem_6_331 |
PubMedID: 15578634 |
Title : Implications of surface charge and curvature for the binding orientation of Thermomyces lanuginosus lipase on negatively charged or zwitterionic phospholipid vesicles as studied by ESR spectroscopy - Hedin_2005_Biochemistry_44_16658 |
Author(s) : Hedin EM , Hoyrup P , Patkar SA , Vind J , Svendsen A , Hult K |
Ref : Biochemistry , 44 :16658 , 2005 |
Abstract : Hedin_2005_Biochemistry_44_16658 |
ESTHER : Hedin_2005_Biochemistry_44_16658 |
PubMedSearch : Hedin_2005_Biochemistry_44_16658 |
PubMedID: 16342956 |
Gene_locus related to this paper: humla-1lipa |
Title : Focusing mutations into the P. fluorescens esterase binding site increases enantioselectivity more effectively than distant mutations - Park_2005_Chem.Biol_12_45 |
Author(s) : Park S , Morley KL , Horsman GP , Holmquist M , Hult K , Kazlauskas RJ |
Ref : Chemical Biology , 12 :45 , 2005 |
Abstract : Park_2005_Chem.Biol_12_45 |
ESTHER : Park_2005_Chem.Biol_12_45 |
PubMedSearch : Park_2005_Chem.Biol_12_45 |
PubMedID: 15664514 |
Title : Modification of cellulose fiber surfaces by use of a lipase and a xyloglucan endotransglycosylase - Gustavsson_2005_Biomacromolecules_6_196 |
Author(s) : Gustavsson MT , Persson PV , Iversen T , Martinelle M , Hult K , Teeri TT , Brumer H, 3rd |
Ref : Biomacromolecules , 6 :196 , 2005 |
Abstract : Gustavsson_2005_Biomacromolecules_6_196 |
ESTHER : Gustavsson_2005_Biomacromolecules_6_196 |
PubMedSearch : Gustavsson_2005_Biomacromolecules_6_196 |
PubMedID: 15638521 |
Title : Polyester coating of cellulose fiber surfaces catalyzed by a cellulose-binding module-Candida antarctica lipase B fusion protein - Gustavsson_2004_Biomacromolecules_5_106 |
Author(s) : Gustavsson MT , Persson PV , Iversen T , Hult K , Martinelle M |
Ref : Biomacromolecules , 5 :106 , 2004 |
Abstract : Gustavsson_2004_Biomacromolecules_5_106 |
ESTHER : Gustavsson_2004_Biomacromolecules_5_106 |
PubMedSearch : Gustavsson_2004_Biomacromolecules_5_106 |
PubMedID: 14715015 |
Title : Interfacial orientation of Thermomyces lanuginosa lipase on phospholipid vesicles investigated by electron spin resonance relaxation spectroscopy - Hedin_2002_Biochemistry_41_14185 |
Author(s) : Hedin EM , Hoyrup P , Patkar SA , Vind J , Svendsen A , Fransson L , Hult K |
Ref : Biochemistry , 41 :14185 , 2002 |
Abstract : Hedin_2002_Biochemistry_41_14185 |
ESTHER : Hedin_2002_Biochemistry_41_14185 |
PubMedSearch : Hedin_2002_Biochemistry_41_14185 |
PubMedID: 12450382 |
Gene_locus related to this paper: humla-1lipa |
Title : Rational design of enantioselective enzymes requires considerations of entropy - Ottosson_2001_Protein.Sci_10_1769 |
Author(s) : Ottosson J , Rotticci-Mulder JC , Rotticci D , Hult K |
Ref : Protein Science , 10 :1769 , 2001 |
Abstract : Ottosson_2001_Protein.Sci_10_1769 |
ESTHER : Ottosson_2001_Protein.Sci_10_1769 |
PubMedSearch : Ottosson_2001_Protein.Sci_10_1769 |
PubMedID: 11514667 |
Title : Improved enantioselectivity of a lipase by rational protein engineering - Rotticci_2001_Chembiochem_2_766 |
Author(s) : Rotticci D , Rotticci-Mulder JC , Denman S , Norin T , Hult K |
Ref : Chembiochem , 2 :766 , 2001 |
Abstract : Rotticci_2001_Chembiochem_2_766 |
ESTHER : Rotticci_2001_Chembiochem_2_766 |
PubMedSearch : Rotticci_2001_Chembiochem_2_766 |
PubMedID: 11948859 |
Title : An active-site titration method for lipases - Rotticci_2000_Biochim.Biophys.Acta_1483_132 |
Author(s) : Rotticci D , Norin T , Hult K , Martinelle M |
Ref : Biochimica & Biophysica Acta , 1483 :132 , 2000 |
Abstract : Rotticci_2000_Biochim.Biophys.Acta_1483_132 |
ESTHER : Rotticci_2000_Biochim.Biophys.Acta_1483_132 |
PubMedSearch : Rotticci_2000_Biochim.Biophys.Acta_1483_132 |
PubMedID: 10601702 |
Title : Mass transport limitations reduce the effective stereospecificity in enzyme-catalyzed kinetic resolution - Rotticci_2000_Org.Lett_2_1373 |
Author(s) : Rotticci D , Norin T , Hult K |
Ref : Org Lett , 2 :1373 , 2000 |
Abstract : Rotticci_2000_Org.Lett_2_1373 |
ESTHER : Rotticci_2000_Org.Lett_2_1373 |
PubMedSearch : Rotticci_2000_Org.Lett_2_1373 |
PubMedID: 10814450 |
Title : The role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase - Martinelle_1996_Protein.Eng_9_519 |
Author(s) : Martinelle M , Holmquist M , Clausen IG , Patkar S , Svendsen A , Hult K |
Ref : Protein Engineering , 9 :519 , 1996 |
Abstract : Martinelle_1996_Protein.Eng_9_519 |
ESTHER : Martinelle_1996_Protein.Eng_9_519 |
PubMedSearch : Martinelle_1996_Protein.Eng_9_519 |
PubMedID: 8862552 |
Gene_locus related to this paper: humla-1lipa |
Title : Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols - Uppenberg_1995_Biochemistry_34_16838 |
Author(s) : Uppenberg J , Ohrner N , Norin M , Hult K , Kleywegt GJ , Patkar S , Waagen V , Anthonsen T , Jones TA |
Ref : Biochemistry , 34 :16838 , 1995 |
Abstract : Uppenberg_1995_Biochemistry_34_16838 |
ESTHER : Uppenberg_1995_Biochemistry_34_16838 |
PubMedSearch : Uppenberg_1995_Biochemistry_34_16838 |
PubMedID: 8527460 |
Gene_locus related to this paper: canar-LipB |
Title : On the interfacial activation of Candida antarctica lipase A and B as compared with Humicola lanuginosa lipase - Martinelle_1995_Biochim.Biophys.Acta_1258_272 |
Author(s) : Martinelle M , Holmquist M , Hult K |
Ref : Biochimica & Biophysica Acta , 1258 :272 , 1995 |
Abstract : Martinelle_1995_Biochim.Biophys.Acta_1258_272 |
ESTHER : Martinelle_1995_Biochim.Biophys.Acta_1258_272 |
PubMedSearch : Martinelle_1995_Biochim.Biophys.Acta_1258_272 |
PubMedID: 7548197 |
Title : Probing a functional role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase through transesterification reactions in organic solvent - Holmquist_1995_J.Protein.Chem_14_217 |
Author(s) : Holmquist M , Clausen IG , Patkar S , Svendsen A , Hult K |
Ref : J Protein Chem , 14 :217 , 1995 |
Abstract : Holmquist_1995_J.Protein.Chem_14_217 |
ESTHER : Holmquist_1995_J.Protein.Chem_14_217 |
PubMedSearch : Holmquist_1995_J.Protein.Chem_14_217 |
PubMedID: 7662109 |
Gene_locus related to this paper: humla-1lipa |
Title : Trp89 in the lid of Humicola lanuginosa lipase is important for efficient hydrolysis of tributyrin - Holmquist_1994_Lipids_29_599 |
Author(s) : Holmquist M , Martinelle M , Clausen IG , Patkar S , Svendsen A , Hult K |
Ref : Lipids , 29 :599 , 1994 |
Abstract : Holmquist_1994_Lipids_29_599 |
ESTHER : Holmquist_1994_Lipids_29_599 |
PubMedSearch : Holmquist_1994_Lipids_29_599 |
PubMedID: 7815893 |
Gene_locus related to this paper: humla-1lipa |
Title : Molecular dynamics simulations of an enzyme surrounded by vacuum, water, or a hydrophobic solvent - Norin_1994_Biophys.J_67_548 |
Author(s) : Norin M , Haeffner F , Hult K , Edholm O |
Ref : Biophysical Journal , 67 :548 , 1994 |
Abstract : Norin_1994_Biophys.J_67_548 |
ESTHER : Norin_1994_Biophys.J_67_548 |
PubMedSearch : Norin_1994_Biophys.J_67_548 |
PubMedID: 7948673 |
Title : Lipases from Rhizomucor miehei and Humicola lanuginosa: modification of the lid covering the active site alters enantioselectivity - Holmquist_1993_J.Protein.Chem_12_749 |
Author(s) : Holmquist M , Martinelle M , Berglund P , Clausen IG , Patkar S , Svendsen A , Hult K |
Ref : J Protein Chem , 12 :749 , 1993 |
Abstract : Holmquist_1993_J.Protein.Chem_12_749 |
ESTHER : Holmquist_1993_J.Protein.Chem_12_749 |
PubMedSearch : Holmquist_1993_J.Protein.Chem_12_749 |
PubMedID: 8136025 |
Title : The role of arginines in stabilizing the active open-lid conformation of Rhizomucor miehei lipase - Holmquist_1993_Lipids_28_721 |
Author(s) : Holmquist M , Norin M , Hult K |
Ref : Lipids , 28 :721 , 1993 |
Abstract : Holmquist_1993_Lipids_28_721 |
ESTHER : Holmquist_1993_Lipids_28_721 |
PubMedSearch : Holmquist_1993_Lipids_28_721 |
PubMedID: 8377587 |
Title : Theoretical studies of Rhizomucor miehei lipase activation - Norin_1993_Protein.Eng_6_855 |
Author(s) : Norin M , Olsen O , Svendsen A , Edholm O , Hult K |
Ref : Protein Engineering , 6 :855 , 1993 |
Abstract : Norin_1993_Protein.Eng_6_855 |
ESTHER : Norin_1993_Protein.Eng_6_855 |
PubMedSearch : Norin_1993_Protein.Eng_6_855 |
PubMedID: 8309933 |