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Author Report for: Hornberg A

Contact information:

Hornberg Andreas
Swedish Defence Research Agency, Division of CBRN Defence and Security, S-901 82 Umea
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    Title: Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6
    Allgardsson A, Berg L, Akfur C, Hornberg A, Worek F, Linusson A, Ekstrom F
    Ref: Proc Natl Acad Sci U S A, 113:5514, 2016 : PubMed


    Title: Targeting acetylcholinesterase: identification of chemical leads by high throughput screening, structure determination and molecular modeling
    Berg L, Andersson CD, Artursson E, Hornberg A, Tunemalm AK, Linusson A, Ekstrom F
    Ref: PLoS ONE, 6:e26039, 2011 : PubMed


    Title: Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad
    Hornberg A, Artursson E, Warme R, Pang YP, Ekstrom F
    Ref: Biochemical Pharmacology, 79:507, 2010 : PubMed


    Title: Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis
    Artursson E, Akfur C, Hornberg A, Worek F, Ekstrom F
    Ref: Toxicology, 265:108, 2009 : PubMed


    Title: Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design
    Ekstrom F, Hornberg A, Artursson E, Hammarstrom LG, Schneider G, Pang YP
    Ref: PLoS ONE, 4:e5957, 2009 : PubMed


    Title: Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state
    Hornberg A, Tunemalm AK, Ekstrom F
    Ref: Biochemistry, 46:4815, 2007 : PubMed


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