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| Title : Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter - Ennis_2015_ACS.Chem.Neurosci_6_417 |
| Author(s) : Ennis EA , Wright J , Retzlaff CL , McManus OB , Lin Z , Huang X , Wu M , Li M , Daniels JS , Lindsley CW , Hopkins CR , Blakely RD |
| Ref : ACS Chem Neurosci , 6 :417 , 2015 |
| Abstract : Ennis_2015_ACS.Chem.Neurosci_6_417 |
| ESTHER : Ennis_2015_ACS.Chem.Neurosci_6_417 |
| PubMedSearch : Ennis_2015_ACS.Chem.Neurosci_6_417 |
| PubMedID: 25560927 |
| Title : Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor - Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| Author(s) : Salovich JM , Vinson PN , Sheffler DJ , Lamsal A , Utley TJ , Blobaum AL , Bridges TM , Le U , Jones CK , Wood MR , Daniels JS , Conn PJ , Niswender CM , Lindsley CW , Hopkins CR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :5084 , 2012 |
| Abstract : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| ESTHER : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| PubMedSearch : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| PubMedID: 22738637 |
| Title : Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery - |
| Author(s) : Melancon BJ , Hopkins CR , Wood MR , Emmitte KA , Niswender CM , Christopoulos A , Conn PJ , Lindsley CW |
| Ref : Journal of Medicinal Chemistry , 55 :1445 , 2012 |
| PubMedID: 22148748 |
| Title : The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease - Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| Author(s) : Jones CK , Bubser M , Thompson AD , Dickerson JW , Turle-Lorenzo N , Amalric M , Blobaum AL , Bridges TM , Morrison RD , Jadhav S , Engers DW , Italiano K , Bode J , Daniels JS , Lindsley CW , Hopkins CR , Conn PJ , Niswender CM |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 340 :404 , 2012 |
| Abstract : Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| ESTHER : Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| PubMedSearch : Jones_2012_J.Pharmacol.Exp.Ther_340_404 |
| PubMedID: 22088953 |
| Title : The antipsychotic potential of muscarinic allosteric modulation - Bridges_2010_Drug.News.Perspect_23_229 |
| Author(s) : Bridges TM , LeBois EP , Hopkins CR , Wood MR , Jones CK , Conn PJ , Lindsley CW |
| Ref : Drug News Perspect , 23 :229 , 2010 |
| Abstract : Bridges_2010_Drug.News.Perspect_23_229 |
| ESTHER : Bridges_2010_Drug.News.Perspect_23_229 |
| PubMedSearch : Bridges_2010_Drug.News.Perspect_23_229 |
| PubMedID: 20520852 |