Full name : Holas Ondrej
First name : Ondrej
Mail : Department of Pharmaceutical Chemistry and Drug Control\; Faculty of Pharmacy in Hradec Kralove\; Charles University in Prague\; 50001 Hradec Kralove
Zip Code :
City :
Country : Czech Republic
Email : holas.ondrej@gmail.com
Phone : +420973251523
Fax :
Website :
Directory :
| Title : Monooxime Bispyridinium Reactivators Bearing Xylene Linker Synthesis and In Vitro Evaluation on Model of Organophosphate-Inhibited Acetylcholinesterase - Musilek_2016_Med.Chem_12_362 |
| Author(s) : Musilek K , Hambalek J , Holas O , Dohnal V , Kuca K |
| Ref : Med Chem , 12 :362 , 2016 |
| Abstract : Musilek_2016_Med.Chem_12_362 |
| ESTHER : Musilek_2016_Med.Chem_12_362 |
| PubMedSearch : Musilek_2016_Med.Chem_12_362 |
| PubMedID: 26427931 |
| Title : Evaluation of 2,6-dichlorophenolindophenol acetate as a substrate for acetylcholinesterase activity assay - Pohanka_2015_J.Enzyme.Inhib.Med.Chem_30_796 |
| Author(s) : Pohanka M , Holas O |
| Ref : J Enzyme Inhib Med Chem , 30 :796 , 2015 |
| Abstract : Pohanka_2015_J.Enzyme.Inhib.Med.Chem_30_796 |
| ESTHER : Pohanka_2015_J.Enzyme.Inhib.Med.Chem_30_796 |
| PubMedSearch : Pohanka_2015_J.Enzyme.Inhib.Med.Chem_30_796 |
| PubMedID: 25672529 |
| Title : Novel tacrine\/acridine anticholinesterase inhibitors with piperazine and thiourea linkers - Hamulakova_2014_Int.J.Biol.Macromol_70C_435 |
| Author(s) : Hamulakova S , Imrich J , Janovec L , Kristian P , Danihel I , Holas O , Pohanka M , Bohm S , Kozurkova M , Kuca K |
| Ref : Int J Biol Macromol , 70C :435 , 2014 |
| Abstract : Hamulakova_2014_Int.J.Biol.Macromol_70C_435 |
| ESTHER : Hamulakova_2014_Int.J.Biol.Macromol_70C_435 |
| PubMedSearch : Hamulakova_2014_Int.J.Biol.Macromol_70C_435 |
| PubMedID: 25036600 |
| Title : The progress in the cholinesterase quantification methods - Holas_2012_Expert.Opin.Drug.Discov_7_1207 |
| Author(s) : Holas O , Musilek K , Pohanka M , Kuca K |
| Ref : Expert Opin Drug Discov , 7 :1207 , 2012 |
| Abstract : Holas_2012_Expert.Opin.Drug.Discov_7_1207 |
| ESTHER : Holas_2012_Expert.Opin.Drug.Discov_7_1207 |
| PubMedSearch : Holas_2012_Expert.Opin.Drug.Discov_7_1207 |
| PubMedID: 23013366 |
| Title : Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment - Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| Author(s) : Komloova M , Musilek K , Horova A , Holas O , Dohnal V , Gunn-Moore F , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2505 , 2011 |
| Abstract : Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| ESTHER : Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| PubMedSearch : Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| PubMedID: 21397501 |
| Title : Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment - Musilek_2011_Eur.J.Med.Chem_46_811 |
| Author(s) : Musilek K , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K |
| Ref : Eur Journal of Medicinal Chemistry , 46 :811 , 2011 |
| Abstract : Musilek_2011_Eur.J.Med.Chem_46_811 |
| ESTHER : Musilek_2011_Eur.J.Med.Chem_46_811 |
| PubMedSearch : Musilek_2011_Eur.J.Med.Chem_46_811 |
| PubMedID: 21236521 |
| Title : The preparation, in vitro screening and molecular docking of symmetrical bisquaternary cholinesterase inhibitors containing a but-(2E)-en-1,4-diyl connecting linkage - Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| Author(s) : Musilek K , Pavlikova R , Marek J , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Dolezal M , Gunn-Moore F , Kuca K |
| Ref : J Enzyme Inhib Med Chem , 26 :245 , 2011 |
| Abstract : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| ESTHER : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| PubMedSearch : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| PubMedID: 21406034 |
| Title : Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking - Musilek_2011_Bioorg.Med.Chem_19_754 |
| Author(s) : Musilek K , Komloova M , Holas O , Horova A , Pohanka M , Gunn-Moore F , Dohnal V , Dolezal M , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 19 :754 , 2011 |
| Abstract : Musilek_2011_Bioorg.Med.Chem_19_754 |
| ESTHER : Musilek_2011_Bioorg.Med.Chem_19_754 |
| PubMedSearch : Musilek_2011_Bioorg.Med.Chem_19_754 |
| PubMedID: 21215642 |
| Title : Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties - Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| Author(s) : Korabecny J , Musilek K , Zemek F , Horova A , Holas O , Nepovimova E , Opletalova V , Hroudova J , Fisar Z , Jung YS , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :6563 , 2011 |
| Abstract : Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| ESTHER : Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| PubMedSearch : Korabecny_2011_Bioorg.Med.Chem.Lett_21_6563 |
| PubMedID: 21920739 |
| Title : Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors--analogues of SAD-128 - Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| Author(s) : Musilek K , Roder J , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Opletalova V , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :150 , 2011 |
| Abstract : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| ESTHER : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| PubMedSearch : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| PubMedID: 21144749 |
| Title : Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications - Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| Author(s) : Musilek K , Komloova M , Zavadova V , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1763 , 2010 |
| Abstract : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| ESTHER : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedSearch : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedID: 20138518 |
| Title : Synthesis and in vitro evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a cholinesterase inhibitor with regard to Alzheimer's disease treatment - Korabecny_2010_Molecules_15_8804 |
| Author(s) : Korabecny J , Musilek K , Holas O , Nepovimova E , Jun D , Zemek F , Opletalova V , Patocka J , Dohnal V , Nachon F , Hroudova J , Fisar Z , Kuca K |
| Ref : Molecules , 15 :8804 , 2010 |
| Abstract : Korabecny_2010_Molecules_15_8804 |
| ESTHER : Korabecny_2010_Molecules_15_8804 |
| PubMedSearch : Korabecny_2010_Molecules_15_8804 |
| PubMedID: 21127466 |
| Title : Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase - Kovarik_2010_Chem.Biol.Interact_187_167 |
| Author(s) : Kovarik Z , Katalinic M , Sinko G , Binder J , Holas O , Jung YS , Musilova L , Jun D , Kuca K |
| Ref : Chemico-Biological Interactions , 187 :167 , 2010 |
| Abstract : Kovarik_2010_Chem.Biol.Interact_187_167 |
| ESTHER : Kovarik_2010_Chem.Biol.Interact_187_167 |
| PubMedSearch : Kovarik_2010_Chem.Biol.Interact_187_167 |
| PubMedID: 20206154 |
| Title : Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease - Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| Author(s) : Korabecny J , Musilek K , Holas O , Binder J , Zemek F , Marek J , Pohanka M , Opletalova V , Dohnal V , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :6093 , 2010 |
| Abstract : Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| ESTHER : Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| PubMedSearch : Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| PubMedID: 20817518 |
| Title : Testing of a Referential Method Based on Indoxylacetate as a Acetylcholinesterase Substrate for Identification of Reactivation Efficacy. - Pohanka_2010_Mil.Med.Sci.Lett_79_111 |
| Author(s) : Pohanka M , Hrabinova M , Karasova JZ , Holas O , Kuca K , Cabal J |
| Ref : Military Medical Science Letters , 79 :111 , 2010 |
| Abstract : Pohanka_2010_Mil.Med.Sci.Lett_79_111 |
| ESTHER : Pohanka_2010_Mil.Med.Sci.Lett_79_111 |
| PubMedSearch : Pohanka_2010_Mil.Med.Sci.Lett_79_111 |
| PubMedID: |
| Title : Colorimetric dipstick for assay of organophosphate pesticides and nerve agents represented by paraoxon, sarin and VX - Pohanka_2010_Talanta_81_621 |
| Author(s) : Pohanka M , Karasova JZ , Kuca K , Pikula J , Holas O , Korabecny J , Cabal J |
| Ref : Talanta , 81 :621 , 2010 |
| Abstract : Pohanka_2010_Talanta_81_621 |
| ESTHER : Pohanka_2010_Talanta_81_621 |
| PubMedSearch : Pohanka_2010_Talanta_81_621 |
| PubMedID: 20188972 |
| Title : Monooxime-monocarbamoyl Bispyridinium Xylene-Linked Reactivators of Acetylcholinesterase-Synthesis, In vitro and Toxicity Evaluation, and Docking Studies - Musilek_2010_ChemMedChem_5_247 |
| Author(s) : Musilek K , Holas O , Misik J , Pohanka M , Novotny L , Dohnal V , Opletalova V , Kuca K |
| Ref : ChemMedChem , 5 :247 , 2010 |
| Abstract : Musilek_2010_ChemMedChem_5_247 |
| ESTHER : Musilek_2010_ChemMedChem_5_247 |
| PubMedSearch : Musilek_2010_ChemMedChem_5_247 |
| PubMedID: 20058292 |
| Title : Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Opletalova V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 23 :70 , 2008 |
| Abstract : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| ESTHER : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| PubMedSearch : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| PubMedID: 18341256 |
| Title : Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Opletalova V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :3172 , 2007 |
| Abstract : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| ESTHER : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| PubMedSearch : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| PubMedID: 17383875 |
| Title : Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 22 :425 , 2007 |
| Abstract : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| ESTHER : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| PubMedSearch : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| PubMedID: 17847708 |
| Title : Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2007_Bioorg.Med.Chem_15_6733 |
| Author(s) : Musilek K , Holas O , Jun D , Dohnal V , Gunn-Moore F , Opletalova V , Dolezal M , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 15 :6733 , 2007 |
| Abstract : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| ESTHER : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| PubMedSearch : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| PubMedID: 17764957 |
| Title : Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5673 , 2006 |
| Abstract : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| ESTHER : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| PubMedSearch : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| PubMedID: 16934462 |