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| Title : Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer's Disease Mouse Model upon Irradiation - Scheiner_2022_J.Am.Chem.Soc__ |
| Author(s) : Scheiner M , Sink A , Hoffmann M , Vrigneau C , Endres E , Carles A , Sotriffer C , Maurice T , Decker M |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : Scheiner_2022_J.Am.Chem.Soc__ |
| ESTHER : Scheiner_2022_J.Am.Chem.Soc__ |
| PubMedSearch : Scheiner_2022_J.Am.Chem.Soc__ |
| PubMedID: 35138833 |
| Title : Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model - Scheiner_2021_J.Med.Chem_64_9302 |
| Author(s) : Scheiner M , Hoffmann M , He F , Poeta E , Chatonnet A , Monti B , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 64(13): :9302 , 2021 |
| Abstract : Scheiner_2021_J.Med.Chem_64_9302 |
| ESTHER : Scheiner_2021_J.Med.Chem_64_9302 |
| PubMedSearch : Scheiner_2021_J.Med.Chem_64_9302 |
| PubMedID: 34152756 |
| Title : Synthesis and Initial Characterization of a Selective, Pseudo-irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer - Gentzsch_2021_ChemMedChem__ |
| Author(s) : Gentzsch C , Hoffmann M , Ohshima Y , Nose N , Chen X , Higuchi T , Decker M |
| Ref : ChemMedChem , : , 2021 |
| Abstract : Gentzsch_2021_ChemMedChem__ |
| ESTHER : Gentzsch_2021_ChemMedChem__ |
| PubMedSearch : Gentzsch_2021_ChemMedChem__ |
| PubMedID: 33645891 |
| Title : Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus - Kleine-Weber_2020_Emerg.Microbes.Infect_9_155 |
| Author(s) : Kleine-Weber H , Schroeder S , Kruger N , Prokscha A , Naim HY , Muller MA , Drosten C , Pohlmann S , Hoffmann M |
| Ref : Emerg Microbes Infect , 9 :155 , 2020 |
| Abstract : Kleine-Weber_2020_Emerg.Microbes.Infect_9_155 |
| ESTHER : Kleine-Weber_2020_Emerg.Microbes.Infect_9_155 |
| PubMedSearch : Kleine-Weber_2020_Emerg.Microbes.Infect_9_155 |
| PubMedID: 31964246 |
| Title : N-1,2,3-triazole-isatin derivatives for cholinesterase and beta-amyloid aggregation inhibition: A comprehensive bioassay study - Marques_2020_Bioorg.Chem_98_103753 |
| Author(s) : Marques CS , Lopez O , Bagetta D , Carreiro EP , Petralla S , Bartolini M , Hoffmann M , Alcaro S , Monti B , Bolognesi ML , Decker M , Fernandez-Bolanos JG , Burke AJ |
| Ref : Bioorg Chem , 98 :103753 , 2020 |
| Abstract : Marques_2020_Bioorg.Chem_98_103753 |
| ESTHER : Marques_2020_Bioorg.Chem_98_103753 |
| PubMedSearch : Marques_2020_Bioorg.Chem_98_103753 |
| PubMedID: 32200328 |
| Title : Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo - Hofmann_2020_Chemistry_26_7299 |
| Author(s) : Hofmann J , Fayez S , Scheiner M , Hoffmann M , Oerter S , Appelt-Menzel A , Maher P , Maurice T , Bringmann G , Decker M |
| Ref : Chemistry , 26 :7299 , 2020 |
| Abstract : Hofmann_2020_Chemistry_26_7299 |
| ESTHER : Hofmann_2020_Chemistry_26_7299 |
| PubMedSearch : Hofmann_2020_Chemistry_26_7299 |
| PubMedID: 32358806 |
| Title : 7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo - Gunesch_2020_Redox.Biol_29_101378 |
| Author(s) : Gunesch S , Hoffmann M , Kiermeier C , Fischer W , Pinto AFM , Maurice T , Maher P , Decker M |
| Ref : Redox Biol , 29 :101378 , 2020 |
| Abstract : Gunesch_2020_Redox.Biol_29_101378 |
| ESTHER : Gunesch_2020_Redox.Biol_29_101378 |
| PubMedSearch : Gunesch_2020_Redox.Biol_29_101378 |
| PubMedID: 31926632 |
| Title : Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo - Scheiner_2019_J.Med.Chem_62_9078 |
| Author(s) : Scheiner M , Dolles D , Gunesch S , Hoffmann M , Nabissi M , Marinelli O , Naldi M , Bartolini M , Petralla S , Poeta E , Monti B , Falkeis C , Vieth M , Hubner H , Gmeiner P , Maitra R , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 62 :9078 , 2019 |
| Abstract : Scheiner_2019_J.Med.Chem_62_9078 |
| ESTHER : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedSearch : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedID: 31609608 |
| Title : Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization - Kleine-Weber_2019_J.Virol_93_ |
| Author(s) : Kleine-Weber H , Elzayat MT , Wang L , Graham BS , Muller MA , Drosten C , Pohlmann S , Hoffmann M |
| Ref : J Virol , 93 : , 2019 |
| Abstract : Kleine-Weber_2019_J.Virol_93_ |
| ESTHER : Kleine-Weber_2019_J.Virol_93_ |
| PubMedSearch : Kleine-Weber_2019_J.Virol_93_ |
| PubMedID: 30404801 |
| Title : Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer's Disease Mouse Model - Hoffmann_2019_J.Med.Chem_62_9116 |
| Author(s) : Hoffmann M , Stiller C , Endres E , Scheiner M , Gunesch S , Sotriffer C , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 62 :9116 , 2019 |
| Abstract : Hoffmann_2019_J.Med.Chem_62_9116 |
| ESTHER : Hoffmann_2019_J.Med.Chem_62_9116 |
| PubMedSearch : Hoffmann_2019_J.Med.Chem_62_9116 |
| PubMedID: 31609115 |
| Title : Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles - Dolles_2018_J.Med.Chem_61_1646 |
| Author(s) : Dolles D , Hoffmann M , Gunesch S , Marinelli O , Moller J , Santoni G , Chatonnet A , Lohse MJ , Wittmann HJ , Strasser A , Nabissi M , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 61 :1646 , 2018 |
| Abstract : Dolles_2018_J.Med.Chem_61_1646 |
| ESTHER : Dolles_2018_J.Med.Chem_61_1646 |
| PubMedSearch : Dolles_2018_J.Med.Chem_61_1646 |
| PubMedID: 29400965 |
| Title : Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals - Hoffmann_2014_Genome.Biol.Evol_6_1046 |
| Author(s) : Hoffmann M , Zhao S , Pettengill J , Luo Y , Monday SR , Abbott J , Ayers SL , Cinar HN , Muruvanda T , Li C , Allard MW , Whichard J , Meng J , Brown EW , McDermott PF |
| Ref : Genome Biol Evol , 6 :1046 , 2014 |
| Abstract : Hoffmann_2014_Genome.Biol.Evol_6_1046 |
| ESTHER : Hoffmann_2014_Genome.Biol.Evol_6_1046 |
| PubMedSearch : Hoffmann_2014_Genome.Biol.Evol_6_1046 |
| PubMedID: 24732280 |
| Title : Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures - Storz_2013_ACS.Chem.Biol_8_2794 |
| Author(s) : Storz MP , Brengel C , Weidel E , Hoffmann M , Hollemeyer K , Steinbach A , Muller R , Empting M , Hartmann RW |
| Ref : ACS Chemical Biology , 8 :2794 , 2013 |
| Abstract : Storz_2013_ACS.Chem.Biol_8_2794 |
| ESTHER : Storz_2013_ACS.Chem.Biol_8_2794 |
| PubMedSearch : Storz_2013_ACS.Chem.Biol_8_2794 |
| PubMedID: 24099650 |
| Title : Complete Genome Sequence of a Multidrug-Resistant Salmonella enterica Serovar Typhimurium var. 5- Strain Isolated from Chicken Breast - Hoffmann_2013_Genome.Announc_1_e01068 |
| Author(s) : Hoffmann M , Muruvanda T , Allard MW , Korlach J , Roberts RJ , Timme R , Payne J , McDermott PF , Evans P , Meng J , Brown EW , Zhao S |
| Ref : Genome Announc , 1 : , 2013 |
| Abstract : Hoffmann_2013_Genome.Announc_1_e01068 |
| ESTHER : Hoffmann_2013_Genome.Announc_1_e01068 |
| PubMedSearch : Hoffmann_2013_Genome.Announc_1_e01068 |
| PubMedID: 24356834 |
| Title : Genome Sequences of Salmonella enterica Serovar Heidelberg Isolates Isolated in the United States from a Multistate Outbreak of Human Salmonella Infections - Hoffmann_2013_Genome.Announc_1_e00004 |
| Author(s) : Hoffmann M , Luo Y , Lafon PC , Timme R , Allard MW , McDermott PF , Brown EW , Zhao S |
| Ref : Genome Announc , 1 : , 2013 |
| Abstract : Hoffmann_2013_Genome.Announc_1_e00004 |
| ESTHER : Hoffmann_2013_Genome.Announc_1_e00004 |
| PubMedSearch : Hoffmann_2013_Genome.Announc_1_e00004 |
| PubMedID: 23405335 |
| Gene_locus related to this paper: salty-STY1441 |
| Title : Genome sequences of five Salmonella enterica serovar Heidelberg isolates associated with a 2011 multistate outbreak in the United States - Hoffmann_2012_J.Bacteriol_194_3274 |
| Author(s) : Hoffmann M , Zhao S , Luo Y , Li C , Folster JP , Whichard J , Allard MW , Brown EW , McDermott PF |
| Ref : Journal of Bacteriology , 194 :3274 , 2012 |
| Abstract : Hoffmann_2012_J.Bacteriol_194_3274 |
| ESTHER : Hoffmann_2012_J.Bacteriol_194_3274 |
| PubMedSearch : Hoffmann_2012_J.Bacteriol_194_3274 |
| PubMedID: 22628505 |
| Gene_locus related to this paper: salty-STY1441 , salty-YFBB |